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M. thermoresistible (build 8) TH_0641 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 1388929 - 1389540
length: 204

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0641--100% (204)transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_4015-1e-1527.59% (203) PUTATIVE -
M. thermoresistible (build 8)TH_3297-3e-1048.44% (64) PUTATIVE transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0279c-2e-2031.63% (196) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_4467-7e-8778.61% (201) TetR family transcriptional regulator
M. tuberculosis H37RvRv0273c-2e-2031.63% (196) transcriptional regulatory protein
M. leprae Br4923MLBr_01070-2e-0723.08% (195) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_0314c-8e-2333.15% (184) TetR family transcriptional regulator
M. marinum MMMAR_1492-2e-8677.34% (203) transcriptional regulatory protein
M. avium 104MAV_4026-5e-9282.18% (202) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2071-9e-8676.73% (202) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_2448-4e-8676.85% (203) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_1893-5e-8578.50% (200) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0279c|M.bovis_AF2122/97           -----------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATT
Rv0273c|M.tuberculosis_H37Rv        -----------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATT
MAB_0314c|M.abscessus_ATCC_199      ---------------------------------MDAARVVISRVGYAETR
Mflv_4467|M.gilvum_PYR-GCK          ------------MPPGS-SDALSAKGRQTRDALAQAARKLFAERGFHGTT
Mvan_1893|M.vanbaalenii_PYR-1       ------------MPPGP-AESLSAKGRQTRDAIEQAARKLFAERGFHGTT
MAV_4026|M.avium_104                ------------MP----AELLTAKGRQTRQAIEQAARKLFAERGFHGTT
MMAR_1492|M.marinum_M               ------------MPARQESRELSSKGRQTRQAIEQAARKLFAERGFHGTT
MUL_2448|M.ulcerans_Agy99           ------------MPARQESRELSSKGRQTRQAIEQVARKLFAERGFHGTT
MSMEG_2071|M.smegmatis_MC2_155      ------------MA----SGELGSKGRQTRTAIELAARKLFAERGFHGTT
TH_0641|M.thermoresistible__bu      ------------MA----AETLSSKGRQTRLALEQAARKLFAERGFHGTT
MLBr_01070|M.leprae_Br4923          MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
                                                                       .*. :. .       

Mb0279c|M.bovis_AF2122/97           VADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS
Rv0273c|M.tuberculosis_H37Rv        VADITAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS
MAB_0314c|M.abscessus_ATCC_199      VIDITTEAGKSVGVFYNYFTDKAELLRTMVDEFRDDAYARGDTVATSDRP
Mflv_4467|M.gilvum_PYR-GCK          LSDITSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVAPSGLSVPLPES
Mvan_1893|M.vanbaalenii_PYR-1       LGDITSAAGKSPAVFYRYFADKEDLLAALAESFLHDVVAPSGLSVPLPES
MAV_4026|M.avium_104                LADITSAAGKSPAVFYRYFADKEDLLAALAESFLHEVVTPSGLSVHLPDS
MMAR_1492|M.marinum_M               LADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTPSGVSLQLPDS
MUL_2448|M.ulcerans_Agy99           LADITSAAGKSSAVFYRYFTDKEDLLAALAQSFLHDVVTPSGVSLQLPDS
MSMEG_2071|M.smegmatis_MC2_155      LADITSAAGKSPAVFYRYFTDKEDLLAALAESFLHDVVEPSGLNLHLPDS
TH_0641|M.thermoresistible__bu      LADITSAAGKSPAVFYRYFVDKEDLLAALAESFLREVLAPGWLSVRLPDS
MLBr_01070|M.leprae_Br4923          VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRS-AVEALAEQLP
                                    : :::  ** *   ** *: .*  ::      :  .    .        .

Mb0279c|M.bovis_AF2122/97           DRER--AYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPI
Rv0273c|M.tuberculosis_H37Rv        DRER--AYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPI
MAB_0314c|M.abscessus_ATCC_199      PHEV--IRDIVTVYWTTYREHAPVLSGVFQAAQVDPTFVDYWRNLRAPAR
Mflv_4467|M.gilvum_PYR-GCK          PDDDAFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQNEFRRFGM
Mvan_1893|M.vanbaalenii_PYR-1       PDDDAFFTMVVTGYWTMFKQNIGIMIAVAQLAATQSRFALVQNEFRRFGM
MAV_4026|M.avium_104                PDDDAFFTAVVTGYWNMFKQNIGIMIAVAQLAATQQRFAAVQNEFRRFGI
MMAR_1492|M.marinum_M               PDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQNQFRRFGM
MUL_2448|M.ulcerans_Agy99           PDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAATQQRFAAVQNQFRRFGM
MSMEG_2071|M.smegmatis_MC2_155      PDDAEFFTSVVTGYWNMFKQNIGIMIAVAQLAATQQRFAEVQNSFRRFGI
TH_0641|M.thermoresistible__bu      PDDDEFFTTVVGGYWNMFKQNIGIMIAVDQLAATQQRFADVQNEFRRFGM
MLBr_01070|M.leprae_Br4923          ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWI
                                                 .:     .     .      ..  .      .     

Mb0279c|M.bovis_AF2122/97           SFITETVKRAQAHGYCVGDDP-QLMAEAIVAMFNQFCYLQLS-GKRSR--
Rv0273c|M.tuberculosis_H37Rv        SFITETVKRAQAHGYCVGDDP-QLMAEAIVAMFNQFCYLQLS-GKRSR--
MAB_0314c|M.abscessus_ATCC_199      TMIANNIRHLQARGYCPGMDP-DITASAIGAMLDYFCYVWLVEGGERG--
Mflv_4467|M.gilvum_PYR-GCK          DIVAASVRRAQEQGYGTELNP-EHTAAAIALLFENFTTVFVGASG-----
Mvan_1893|M.vanbaalenii_PYR-1       DIVAASVRRAQEQGYGRELNA-EHTAAAIALLFENFTTVFVGASG-----
MAV_4026|M.avium_104                DLVAASVRRAQEQGYGTELHP-QHTAAAIALLFENFTTVFVGPSG-----
MMAR_1492|M.marinum_M               DIIAASVRHAQDQGYGTELNP-DHTAVAIALLFENFTSVLVGTSGSSGPG
MUL_2448|M.ulcerans_Agy99           DIIAASVRHAQDQGYGTELNP-DHTAVAIALLFENFTSVLVGTSGSSGPG
MSMEG_2071|M.smegmatis_MC2_155      DIVVASVRRAQEQGHAVGLVP-EHIGAAIALLFENFTTVFVGSSG-----
TH_0641|M.thermoresistible__bu      DIVAASVRHAQQQGYGTDLDP-QHIAAAIALMFENFTAVFVGRGG-----
MLBr_01070|M.leprae_Br4923          DYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEK-----
                                       .  ::  :  *      . :  . *:  : : .    .         

Mb0279c|M.bovis_AF2122/97           --RGQPDDQACIQTLANIYYRAIYSKEDSSN---
Rv0273c|M.tuberculosis_H37Rv        --RGQPDDQACIQTLANIYYRAIYSKEDSSN---
MAB_0314c|M.abscessus_ATCC_199      --RSAVTDEEAIDTLARIWFNALWWKSEGAHGAT
Mflv_4467|M.gilvum_PYR-GCK          -LGVQMTDQDAIATLSRIWKKTLYGY--------
Mvan_1893|M.vanbaalenii_PYR-1       -LDVDIDDEAAIATLSRIWKKTLYGY--------
MAV_4026|M.avium_104                -LGIEISDEDAIATLSTIWKKTLYGV--------
MMAR_1492|M.marinum_M               GLGVTITDEDAITTLSRIWKKTLYGF--------
MUL_2448|M.ulcerans_Agy99           GLGVTITDEDAITTLSRIWKKTLYGF--------
MSMEG_2071|M.smegmatis_MC2_155      -LGVELDDREAITTLATIWKKTLYGF--------
TH_0641|M.thermoresistible__bu      -PGLQISDADAVRTLATIWKKTLYGC--------
MLBr_01070|M.leprae_Br4923          ---PLIPDKKVIDTLVHIWLASIYGS--------
                                           *   : **  *:  :::