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PRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAFE ALRPVFEAQGRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQSLLRRISAIWEDRFRPVLTEV IAQGVAEGVFDTFDPEGVGDMIQGLAATMGTAVQRIIAAPDAPARAQAIDAAVLRQRLYGIATDRILGLP DGTVEVLDRDQIEALVAML*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3586c | - | - | 100% (230) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4046c | - | 1e-10 | 30.30% (198) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0599 | - | 3e-09 | 28.28% (145) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 8e-12 | 33.77% (154) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1483 | - | 5e-09 | 28.86% (149) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 9e-12 | 33.77% (154) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 2e-08 | 36.92% (65) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_5046 | - | 2e-10 | 32.05% (156) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 3e-12 | 34.93% (146) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 9e-10 | 27.22% (158) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 1e-11 | 27.92% (154) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2648 | - | 1e-08 | 38.46% (65) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4729 | - | 5e-82 | 65.50% (229) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3586c|M.abscessus_ATCC_199 -----------------------------MPR-VVKHPELRRTELLDLAM
Mvan_4729|M.vanbaalenii_PYR-1 -----------------------------MPR-VVKPKDVRRAEVLDRAL
Mflv_1483|M.gilvum_PYR-GCK -----------------------------MDRALPS----RRDELLQLAA
MSMEG_6009|M.smegmatis_MC2_155 -----------------------------MAPDTPSQPASRRDELLQLAA
Mb3587c|M.bovis_AF2122/97 -----------------------------MDR-VAGQVNSRRGELLELAA
Rv3557c|M.tuberculosis_H37Rv -----------------------------MDR-VAGQVNSRRGELLELAA
MMAR_5046|M.marinum_M -----------------------------MER-MTGQANSRRGELLGLAA
MAV_0603|M.avium_104 ---------------------------------MTGPANSRRDELLELAA
MLBr_00717|M.leprae_Br4923 ----------------------------MTTARRRLSPEDRRAELLALGA
MUL_2648|M.ulcerans_Agy99 ----------------------------MATARRRLSPEDRRAELLALGA
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVSAAA
* *:: .
MAB_3586c|M.abscessus_ATCC_199 TLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAF
Mvan_4729|M.vanbaalenii_PYR-1 ALFLERGYENVSLNDLLAVSGTSKGAFYHYFPSKEALVVALAQRSAGEAF
Mflv_1483|M.gilvum_PYR-GCK TMFADRGLRATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLKDFLDWLF
MSMEG_6009|M.smegmatis_MC2_155 TMFADRGLKATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLF
Mb3587c|M.bovis_AF2122/97 AMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLF
Rv3557c|M.tuberculosis_H37Rv AMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLF
MMAR_5046|M.marinum_M VMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLF
MAV_0603|M.avium_104 AMFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLF
MLBr_00717|M.leprae_Br4923 EVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLY
MUL_2648|M.ulcerans_Agy99 EVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLY
TH_2855|M.thermoresistible__bu EFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTKEPN
.* . . : :: * . :**:* .*. :. :
MAB_3586c|M.abscessus_ATCC_199 EALRPVFEAQGRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQ
Mvan_4729|M.vanbaalenii_PYR-1 EVLRPVFDQPGKNALERLNAGLAASYQVKLGMGVPEPIAAMRSLLMPENQ
Mflv_1483|M.gilvum_PYR-GCK TRYDEIVAATT-DPLERVSGLFMVSFEAIEHRHAQVVIYQDEAKRLNSLP
MSMEG_6009|M.smegmatis_MC2_155 GRYQQILDTAT-SPLEKLTGLFMASFEAIEHRHAQVVIYQDEAKRLSDLP
Mb3587c|M.bovis_AF2122/97 ARYRDIVDSTA-NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQP
Rv3557c|M.tuberculosis_H37Rv ARYRDIVDSTA-NPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQP
MMAR_5046|M.marinum_M ARYLEIVDGEP-NPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSSQP
MAV_0603|M.avium_104 ARYREIIDSES-NPLERLKGLFMASFEAIEHRHAQVVIYQDEAKRLLSQP
MLBr_00717|M.leprae_Br4923 AAT-NIPPPAGLTMFEEVRVGVLA--YMAYHKQNPEAAWAAYVGLGRSDP
MUL_2648|M.ulcerans_Agy99 EAT-SIESPVGMTMFEEIRLGVLA--YMAYHQQNPEAAWAAYVGLGRSDP
TH_2855|M.thermoresistible__bu ELNLPLLDAAG-TPAERLSALIRAHLEHLIRRRVEHLVALHDINSLTPEH
: *.: . .
MAB_3586c|M.abscessus_ATCC_199 SLLRRISAIWEDRFRPVLT---EVIAQGVAEGVFDTFDPEGVGDMIQGLA
Mvan_4729|M.vanbaalenii_PYR-1 ALFRKIVTIWEDLFRPVLT---EVITQGVREGVFDTFDPEGVGDMIQGFA
Mflv_1483|M.gilvum_PYR-GCK QFG--FLDDRNRQQRRMWV---EVLKQGIAEGSFR---PDIDVDLVYRFI
MSMEG_6009|M.smegmatis_MC2_155 QFD--FVETRNKEQRKMWV---DILQEGVADGSFR---PDLDVDLVYRFI
Mb3587c|M.bovis_AF2122/97 RFS--YIEDRNKQQRKMWV---DVLNQGIEEGYFR---PDLDVDLVYRFI
Rv3557c|M.tuberculosis_H37Rv RFS--YIEDRNKQQRKMWV---DVLNQGIEEGYFR---PDLDVDLVYRFI
MMAR_5046|M.marinum_M RFS--YLEDRNKEQRKMWV---DVLNQGIEEGYFR---PDLDVDLVYRFI
MAV_0603|M.avium_104 RFS--YIEDMNRQQRKMWL---EVLNQGVDEGYFR---PDLDVDLVYRFI
MLBr_00717|M.leprae_Br4923 VLLGIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERDLRVIVHGWL
MUL_2648|M.ulcerans_Agy99 VLLGIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERDLRVIIYGWL
TH_2855|M.thermoresistible__bu RAI---IDDLRRYYQRRVR---DVIVAGVRSGEFDVPDPKLAALLILDAL
. . ::: . : ::
MAB_3586c|M.abscessus_ATCC_199 ATMGTAVQRIIAAPDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEV
Mvan_4729|M.vanbaalenii_PYR-1 ASIQDYLVRMFDAADAKSRRKTIDDCVKRLKLYGIATDRILGLPDGATVV
Mflv_1483|M.gilvum_PYR-GCK RDTTWVSVRWYQPGGP-LTAEQVGRQYLAIVLGGITE--------GSK--
MSMEG_6009|M.smegmatis_MC2_155 RDTTWVSVRWYKPGGP-LSAEQVGQQYLAIVLGGITQS------QGDKHA
Mb3587c|M.bovis_AF2122/97 RDTTWVSVRWYRPGGP-LTAQQVGQQYLAIVLGGITK-------EGV---
Rv3557c|M.tuberculosis_H37Rv RDTTWVSVRWYRPGGP-LTAQQVGQQYLAIVLGGITK-------EGV---
MMAR_5046|M.marinum_M RDTTWVSVRWYKPGGA-LTAQQVGQKYLAIVLGGIQK-------EGV---
MAV_0603|M.avium_104 RDTTWVSVRWYQPGGP-LTAEQVGQQYLAIVLGGITV-------DAKKD-
MLBr_00717|M.leprae_Br4923 AFTFEVCRQRIMDPST--DADRLADSCAHALLDAIARVPEISKELADAMA
MUL_2648|M.ulcerans_Agy99 AFTFEICRQRIMDPGT--DADRLADACAHTLLDSIARVPEIPGELAEAMA
TH_2855|M.thermoresistible__bu NG----VSGWFHPDRG-HSLPDVIAAYTEMIVERVLR--------ARIS-
: : : .
MAB_3586c|M.abscessus_ATCC_199 LDRDQIEALVAML----------
Mvan_4729|M.vanbaalenii_PYR-1 LERKQVEAMMTLFMPSRPAGSLP
Mflv_1483|M.gilvum_PYR-GCK -----------------------
MSMEG_6009|M.smegmatis_MC2_155 -----------------------
Mb3587c|M.bovis_AF2122/97 -----------------------
Rv3557c|M.tuberculosis_H37Rv -----------------------
MMAR_5046|M.marinum_M -----------------------
MAV_0603|M.avium_104 -----------------------
MLBr_00717|M.leprae_Br4923 IARQPPQ----------------
MUL_2648|M.ulcerans_Agy99 TARHTPQ----------------
TH_2855|M.thermoresistible__bu -----------------------