For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AEKSAPRRTSGGPVLLDDVTTAIEKAFFEELAAVGYGRLSVDAVARRAGVGKAAIYRRWRSKQALAADLV AKVAVTAIDVPDTGSLRGDIREYLRNGREALTHRLARKIIPDLIAEAVRDPEYGALLTDLIREPRRGRGS HIFERAIERGEIAPDADIDVALDVLAGALYWRQSILQTTADDDYLDRLTEVVLMAVGMGK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5340 | - | - | 100% (201) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 6e-33 | 40.80% (174) | putative TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0465 | - | 7e-24 | 38.29% (175) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 2e-19 | 32.79% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4384 | - | 3e-19 | 30.90% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-19 | 32.79% (183) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3151 | - | 2e-28 | 40.31% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 3e-18 | 34.43% (183) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 2e-20 | 34.27% (178) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 1e-15 | 34.09% (176) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4780 | - | 9e-18 | 34.43% (183) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 8e-20 | 30.90% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0340|M.marinum_M -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MUL_4780|M.ulcerans_Agy99 -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
MAV_5165|M.avium_104 -------------------MDFGRPRDPRIDAAVLRATVELLAETGYPGL
Mflv_4384|M.gilvum_PYR-GCK MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVELLAESSYAEL
Mvan_1961|M.vanbaalenii_PYR-1 ---------------------MGRPRNRAIDDAVLRATVELISESSYAEL
Mb3192c|M.bovis_AF2122/97 --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
Rv3167c|M.tuberculosis_H37Rv --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
MSMEG_5340|M.smegmatis_MC2_155 ----------MAEKSAPRRTSGGPVLLDDVTTAIEKAFFEELAAVGYGRL
MAB_3151|M.abscessus_ATCC_1997 ----------MTKNAATQRQRTSGRLNRSLDIAILEAAFVTLAEQGYDAM
TH_4110|M.thermoresistible__bu -------VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISAL
. : *: * : . :
MMAR_0340|M.marinum_M LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAAT------AVPDTG
MUL_4780|M.ulcerans_Agy99 LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAAT------AVPDTG
MAV_5165|M.avium_104 LVSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFPVGADT------AIPDTG
Mflv_4384|M.gilvum_PYR-GCK SLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFPLGADT------AIPGSG
Mvan_1961|M.vanbaalenii_PYR-1 SLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFPVDATI------EIPRTG
Mb3192c|M.bovis_AF2122/97 SLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTA------LQAAAG
Rv3167c|M.tuberculosis_H37Rv SLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTA------LQAAAG
MSMEG_5340|M.smegmatis_MC2_155 SVDAVARRAGVGKAAIYRRWRSKQALAAD--LVAKVAVTAI--D-VPDTG
MAB_3151|M.abscessus_ATCC_1997 SMDNIAARAGVGKAAIYRRWSSKAALTADAILHGRPSLGKL--DEVPDTG
TH_4110|M.thermoresistible__bu SIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEASVS
: :* ***. *.::**** .* *. : . .
MMAR_0340|M.marinum_M SPVDDLREMVRRTTAVLSTPAAKAALPGLIGEMAADPTLHSALLVRFGEI
MUL_4780|M.ulcerans_Agy99 SPVDDLREMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEI
MAV_5165|M.avium_104 STADDLREMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGA
Mflv_4384|M.gilvum_PYR-GCK SLEADVREMTRRTLAVLSTPAALAALPGLVGEMASDPTLHTALLERFGDI
Mvan_1961|M.vanbaalenii_PYR-1 SLHGDVREMLRRTLAVLSTPAARAALPGLVGEMASDPTLHAALLERFADV
Mb3192c|M.bovis_AF2122/97 DIAADIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADL
Rv3167c|M.tuberculosis_H37Rv DIAADIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADL
MSMEG_5340|M.smegmatis_MC2_155 SLRGDIREYLRNGREALTHRLARKIIPDLIAEAVRDPEYGALLTDLIREP
MAB_3151|M.abscessus_ATCC_1997 SLRGDLHSLYEARDFGDDQVLTGNLLAGIIAEAVNDPTLAAALDDLLVSQ
TH_4110|M.thermoresistible__bu DPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYILP
. :: . : .. . ..
MMAR_0340|M.marinum_M FGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGV
MUL_4780|M.ulcerans_Agy99 FGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGV
MAV_5165|M.avium_104 IGGGLADWLAAAAARGEARPDVTAAELAETIAGVTLVALLTRPTELD---
Mflv_4384|M.gilvum_PYR-GCK LVRGLTEFLESAVRRGDVRPDVTASDLAEAVAGMTLLALLTRGTAVD---
Mvan_1961|M.vanbaalenii_PYR-1 LVRDLNNYLDSAVRRGEVRRGVTAVELAEAVTGMTLLALITRGANVD---
Mb3192c|M.bovis_AF2122/97 FAA-VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD--
Rv3167c|M.tuberculosis_H37Rv FAA-VRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD--
MSMEG_5340|M.smegmatis_MC2_155 RRGRGSHIFERAIERGEIAPDADIDVALDVLAGALYWRQSILQTTAD---
MAB_3151|M.abscessus_ATCC_1997 THKRMELVFARAVERGEITQGRDLSLVYDIPLG-LSLTAALKRTVID---
TH_4110|M.thermoresistible__bu RRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQPEPPSAR--
: * * . : *
MMAR_0340|M.marinum_M GDAWIDRTTTLLLKGIRKGTPQ----
MUL_4780|M.ulcerans_Agy99 GDAWIDRTTTLLLKGIRKGTPQ----
MAV_5165|M.avium_104 -DAWVDRTTRLLLKGISA--------
Mflv_4384|M.gilvum_PYR-GCK -EVWLDRTARLITKGISA--------
Mvan_1961|M.vanbaalenii_PYR-1 -DAWIERTAHLITKGISS--------
Mb3192c|M.bovis_AF2122/97 -DAWVDQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv -DAWVDQTTAIVVRGVHRAAPGGSVV
MSMEG_5340|M.smegmatis_MC2_155 -DDYLDRLTEVVLMAVGMGK------
MAB_3151|M.abscessus_ATCC_1997 -ETYMHRMVEEVILPLVQAPTTHT--
TH_4110|M.thermoresistible__bu ---QLRCYLEVAYRQVGLLP------
: :