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IRVFLVDDHEVVRRGLIDLLSADPELDVIGEADSVSQALARIPAAQPDVAVLDVRLPDGNGIELCRDLLS HMPNLRCLMLTSFTSDEAMLDAILAGASGYVVKDIKGMELAQAIKDVGAGKSLLDNRAATALMSKLRGDA ERSDPLSGLTQQERVLLDLLGEGLTNKQIAARMFLAEKTVKNYVSRLLAKLGMERRTQAAVFASKLDRRN *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5244 | - | - | 100% (211) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_3944 | - | 1e-91 | 80.77% (208) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_6236 | - | 5e-39 | 40.87% (208) | two-component system, regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 1e-97 | 84.69% (209) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 1e-101 | 88.52% (209) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 1e-97 | 84.69% (209) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_00174 | - | 3e-09 | 29.34% (167) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 2e-84 | 72.04% (211) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_3480 | - | 4e-97 | 85.99% (207) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4109 | - | 8e-96 | 83.33% (210) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 5e-98 | 85.17% (209) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 8e-97 | 85.65% (209) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | 1e-102 | 88.15% (211) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3157c|M.bovis_AF2122/97 MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
Rv3133c|M.tuberculosis_H37Rv MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
MUL_2423|M.ulcerans_Agy99 MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSEAMARIPAANPDV
MMAR_3480|M.marinum_M MVKVFLVDDHEVVRRGLVDLLGSDPDLEIIGEAGSVSEAMARIPALQPDV
MAV_4109|M.avium_104 MVKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAEAKARIPAARPDV
Mflv_3847|M.gilvum_PYR-GCK MVKVFLVDDHEVVRRGLIDLLGSDPELDVVGEAGSVSEALTRVPTAQPDV
Mvan_2548|M.vanbaalenii_PYR-1 MVKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAEALARIPALQPDV
MSMEG_5244|M.smegmatis_MC2_155 MIRVFLVDDHEVVRRGLIDLLSADPELDVIGEADSVSQALARIPAAQPDV
TH_2159|M.thermoresistible__bu MVSVFLVDDHEVVRRGLIDLLDSDPDLEVVGEAGTVAQAMARIPAAQPDV
MAB_3891c|M.abscessus_ATCC_199 MITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAEAMARIPALQPDI
MLBr_00174|M.leprae_Br4923 -MRILAVDDDRAVRESLRRSLSFNG--YSVELANDGVEALEMVARDRPDA
: :: ***...**..* * : : *. :* :. .**
Mb3157c|M.bovis_AF2122/97 AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
Rv3133c|M.tuberculosis_H37Rv AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
MUL_2423|M.ulcerans_Agy99 AVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAILAGASG
MMAR_3480|M.marinum_M AVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSDEAMLEAILAGASG
MAV_4109|M.avium_104 AVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAILAGASG
Mflv_3847|M.gilvum_PYR-GCK AVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAILAGASG
Mvan_2548|M.vanbaalenii_PYR-1 AVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAILAGASG
MSMEG_5244|M.smegmatis_MC2_155 AVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAILAGASG
TH_2159|M.thermoresistible__bu AVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAILAGASG
MAB_3891c|M.abscessus_ATCC_199 AVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIMAGAGG
MLBr_00174|M.leprae_Br4923 LVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADD
***: :* :*:*:**:* : :* *:**: . : .: ***..
Mb3157c|M.bovis_AF2122/97 YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
Rv3133c|M.tuberculosis_H37Rv YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
MUL_2423|M.ulcerans_Agy99 YVVKDIKGMELARAIKEVGAGRSLLDNRAAAAL------MSRLRGVVERP
MMAR_3480|M.marinum_M YVVKDIKGMELARAIKDVGAGKSLLDNRAAAAL------MAKLRGGAEQK
MAV_4109|M.avium_104 FVIKDIKGMELARAIKDVGAGKSLLDNRAAAAL------MAKLRGSAAQA
Mflv_3847|M.gilvum_PYR-GCK YVVKDIKGMELARAIKEVGSGRSLLDNRAAAAL------MAKLRGEGERT
Mvan_2548|M.vanbaalenii_PYR-1 YVVKDIKGMELAQAIKDVGSGRSLLDNRAAAAL------MARLRGEGERT
MSMEG_5244|M.smegmatis_MC2_155 YVVKDIKGMELAQAIKDVGAGKSLLDNRAATAL------MSKLRGDAERS
TH_2159|M.thermoresistible__bu YVVKDIKGMELAQAIKDVGAGRSLLDNRAAEAL------MAKLRGADHQP
MAB_3891c|M.abscessus_ATCC_199 YVIKDIKGMELISAVRTVGAGRSLLDNRAAAAL------MNRLRAAADNP
MLBr_00174|M.leprae_Br4923 YLPKPFALEELLARIRALLRRTKPDDAAESVAMSFSDLTLDPVTREVARG
:: * : ** :: : . * : *: : : .
Mb3157c|M.bovis_AF2122/97 DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
Rv3133c|M.tuberculosis_H37Rv DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
MUL_2423|M.ulcerans_Agy99 DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
MMAR_3480|M.marinum_M DPLSGLTEQERTLLGHLSEG----LTNRQIAARMF-----LAEKTVKNYV
MAV_4109|M.avium_104 DPLSGLTEQERTLLGLLSEG----LTNRQIAARMF-----LAEKTVKNYV
Mflv_3847|M.gilvum_PYR-GCK DPLSGLTDQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
Mvan_2548|M.vanbaalenii_PYR-1 DPLSGLTEQERVLLGLLGEG----LTNKQIAARMF-----LAEKTVKNYV
MSMEG_5244|M.smegmatis_MC2_155 DPLSGLTQQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
TH_2159|M.thermoresistible__bu DPLAGLSDQERVLLSLIGEG----LTNKQIAARMF-----LAEKTVKNYV
MAB_3891c|M.abscessus_ATCC_199 SPLAGLTAQERTLLELIGEG----LTNRQIAERMF-----LAEKTVKNYV
MLBr_00174|M.leprae_Br4923 QRWISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYV
. .*: * .** : . **. :* .:: : :::: **
Mb3157c|M.bovis_AF2122/97 SRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
Rv3133c|M.tuberculosis_H37Rv SRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
MUL_2423|M.ulcerans_Agy99 SRLLAKLGMERRTQAAVFAAELKR--ARSAGHR----
MMAR_3480|M.marinum_M SRLLAKLGMERRTQAAVFASRLGQ--GTRPVQGD---
MAV_4109|M.avium_104 SRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
Mflv_3847|M.gilvum_PYR-GCK SRLLAKLGMERRTQAAVFISKLDR--GHGAGNA----
Mvan_2548|M.vanbaalenii_PYR-1 SRLLAKLGMERRTQAAVFVSKLER--HHRPDGE----
MSMEG_5244|M.smegmatis_MC2_155 SRLLAKLGMERRTQAAVFASKLDR--RN---------
TH_2159|M.thermoresistible__bu SRLLAKLGMERRTQAAVFVSKLDR--PIDPRG-----
MAB_3891c|M.abscessus_ATCC_199 SRLLTKLDLERRTQVAVLATKLAR--ENQGLHG----
MLBr_00174|M.leprae_Br4923 GYLRRKTEADGESRLIHTVRGVGYVLRETPP------
. * * : .:: :