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VKVFLVDDHEVVRRGLVDLLGSDPDLEIIGEAGSVSEAMARIPALQPDVAVLDVRLPDGNGIELCRDLLS DLPELRCLMLTSFTSDEAMLEAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLRGGA EQKDPLSGLTEQERTLLGHLSEGLTNRQIAARMFLAEKTVKNYVSRLLAKLGMERRTQAAVFASRLGQGT RPVQGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3480 | - | - | 100% (217) | two-component transcriptional regulatory protein |
| M. marinum M | MMAR_1516 | devR | 5e-95 | 84.54% (207) | two-component transcriptional regulatory protein DevR |
| M. marinum M | MMAR_3959 | - | 9e-28 | 33.17% (208) | two-component transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 1e-100 | 84.26% (216) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 1e-97 | 84.76% (210) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 1e-100 | 84.26% (216) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_00773 | mtrA | 1e-09 | 30.43% (115) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 3e-83 | 70.37% (216) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_4109 | - | 1e-101 | 90.43% (209) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 4e-97 | 85.99% (207) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 2e-95 | 81.22% (213) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 3e-95 | 84.54% (207) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | 1e-100 | 86.38% (213) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3480|M.marinum_M ----MVKVFLVDDHEVVRRGLVDLLGSD-PDLEIIGEAGSVSEAMARIPA
MAV_4109|M.avium_104 ----MVKVFLVDDHEVVRRGLCDLLSSD-PDLRIVGEAGTVAEAKARIPA
Mflv_3847|M.gilvum_PYR-GCK ----MVKVFLVDDHEVVRRGLIDLLGSD-PELDVVGEAGSVSEALTRVPT
Mvan_2548|M.vanbaalenii_PYR-1 ----MVKVFLVDDHEVVRRGLIDLLSSD-PELDVVGEAGSVAEALARIPA
MSMEG_5244|M.smegmatis_MC2_155 ----MIRVFLVDDHEVVRRGLIDLLSAD-PELDVIGEADSVSQALARIPA
TH_2159|M.thermoresistible__bu ----MVSVFLVDDHEVVRRGLIDLLDSD-PDLEVVGEAGTVAQAMARIPA
Mb3157c|M.bovis_AF2122/97 ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
Rv3133c|M.tuberculosis_H37Rv ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
MUL_2423|M.ulcerans_Agy99 ----MVTVFLVDDHEVVRRGLIDLLDAD-PQLDVVGEAGSVSEAMARIPA
MAB_3891c|M.abscessus_ATCC_199 ----MITVFLVDDHEVVRRGLADLLEEE-ADFSVIGQASSVAEAMARIPA
MLBr_00773|M.leprae_Br4923 MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDG---TQALTAVRE
:::***. : . * :* : : ::*:. ::* : :
MMAR_3480|M.marinum_M LQPDVAVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSDEAMLEAIL
MAV_4109|M.avium_104 ARPDVAVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAIL
Mflv_3847|M.gilvum_PYR-GCK AQPDVAVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAIL
Mvan_2548|M.vanbaalenii_PYR-1 LQPDVAVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAIL
MSMEG_5244|M.smegmatis_MC2_155 AQPDVAVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAIL
TH_2159|M.thermoresistible__bu AQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAIL
Mb3157c|M.bovis_AF2122/97 ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
Rv3133c|M.tuberculosis_H37Rv ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
MUL_2423|M.ulcerans_Agy99 ANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAIL
MAB_3891c|M.abscessus_ATCC_199 LQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIM
MLBr_00773|M.leprae_Br4923 LRPDLVLLDLMLPGMNGIDVCRVLRADS-GVPIVMLTAKTDTVDVVLGLE
.**:.:**: **. :*:::** * : : ::**: *. :: .:
MMAR_3480|M.marinum_M AGASGYVVKDIKGMELARAIKD---VGAGKSLLDNRAAAALMAKLRGGAE
MAV_4109|M.avium_104 AGASGFVIKDIKGMELARAIKD---VGAGKSLLDNRAAAALMAKLRGSAA
Mflv_3847|M.gilvum_PYR-GCK AGASGYVVKDIKGMELARAIKE---VGSGRSLLDNRAAAALMAKLRGEGE
Mvan_2548|M.vanbaalenii_PYR-1 AGASGYVVKDIKGMELAQAIKD---VGSGRSLLDNRAAAALMARLRGEGE
MSMEG_5244|M.smegmatis_MC2_155 AGASGYVVKDIKGMELAQAIKD---VGAGKSLLDNRAATALMSKLRGDAE
TH_2159|M.thermoresistible__bu AGASGYVVKDIKGMELAQAIKD---VGAGRSLLDNRAAEALMAKLRGADH
Mb3157c|M.bovis_AF2122/97 AGASGYVVKDIKGMELARAVKD---VGAGRSLLDNRAAAALMAKLRGAAE
Rv3133c|M.tuberculosis_H37Rv AGASGYVVKDIKGMELARAVKD---VGAGRSLLDNRAAAALMAKLRGAAE
MUL_2423|M.ulcerans_Agy99 AGASGYVVKDIKGMELARAIKE---VGAGRSLLDNRAAAALMSRLRGVVE
MAB_3891c|M.abscessus_ATCC_199 AGAGGYVIKDIKGMELISAVRT---VGAGRSLLDNRAAAALMNRLRAAAD
MLBr_00773|M.leprae_Br4923 SGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVDIDVPAHKVT
:**..:::* :* ** :: . ... * . :
MMAR_3480|M.marinum_M QKDPLSGLTEQERTLLGHLSEG---------LTNRQIAARMFLAEKTVKN
MAV_4109|M.avium_104 QADPLSGLTEQERTLLGLLSEG---------LTNRQIAARMFLAEKTVKN
Mflv_3847|M.gilvum_PYR-GCK RTDPLSGLTDQERVLLDLLGEG---------LTNKQIAARMFLAEKTVKN
Mvan_2548|M.vanbaalenii_PYR-1 RTDPLSGLTEQERVLLGLLGEG---------LTNKQIAARMFLAEKTVKN
MSMEG_5244|M.smegmatis_MC2_155 RSDPLSGLTQQERVLLDLLGEG---------LTNKQIAARMFLAEKTVKN
TH_2159|M.thermoresistible__bu QPDPLAGLSDQERVLLSLIGEG---------LTNKQIAARMFLAEKTVKN
Mb3157c|M.bovis_AF2122/97 KQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVKN
Rv3133c|M.tuberculosis_H37Rv KQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVKN
MUL_2423|M.ulcerans_Agy99 RPDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVKN
MAB_3891c|M.abscessus_ATCC_199 NPSPLAGLTAQERTLLELIGEG---------LTNRQIAERMFLAEKTVKN
MLBr_00773|M.leprae_Br4923 RNGEHISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNV
. . .*: * ** :.. * :: . * : *:
MMAR_3480|M.marinum_M YVSRLLAKLGMERRTQAAVFASRLGQ--GTRPVQGD---
MAV_4109|M.avium_104 YVSRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
Mflv_3847|M.gilvum_PYR-GCK YVSRLLAKLGMERRTQAAVFISKLDR--GHGAGNA----
Mvan_2548|M.vanbaalenii_PYR-1 YVSRLLAKLGMERRTQAAVFVSKLER--HHRPDGE----
MSMEG_5244|M.smegmatis_MC2_155 YVSRLLAKLGMERRTQAAVFASKLDR--RN---------
TH_2159|M.thermoresistible__bu YVSRLLAKLGMERRTQAAVFVSKLDR--PIDPRG-----
Mb3157c|M.bovis_AF2122/97 YVSRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
Rv3133c|M.tuberculosis_H37Rv YVSRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
MUL_2423|M.ulcerans_Agy99 YVSRLLAKLGMERRTQAAVFAAELKR--ARSAGHR----
MAB_3891c|M.abscessus_ATCC_199 YVSRLLTKLDLERRTQVAVLATKLAR--ENQGLHG----
MLBr_00773|M.leprae_Br4923 HVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP-------
:*.** :*: : .. ..*: .