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VKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDVAVLDVRLPDGNGIELCRDLLS RMPDLRCLILTSYTSDEAMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLRGAA EKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRLLAKLGMERRTQAAVFATELKRSR PPGDGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3133c | devR | - | 100% (217) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY LUXR/UHPA-FAMILY) |
| M. tuberculosis H37Rv | Rv0844c | narL | 5e-24 | 32.02% (203) | nitrate/nitrite response transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1626 | - | 4e-09 | 27.19% (114) | two-component system transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 1e-118 | 100.00% (217) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 1e-99 | 85.12% (215) | two component LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00174 | - | 4e-10 | 34.75% (118) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 3e-83 | 71.77% (209) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_1516 | devR | 1e-105 | 89.72% (214) | two-component transcriptional regulatory protein DevR |
| M. avium 104 | MAV_4109 | - | 1e-98 | 84.65% (215) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 2e-97 | 84.69% (209) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 1e-97 | 83.10% (213) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 1e-105 | 89.72% (214) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | 1e-101 | 85.65% (216) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3133c|M.tuberculosis_H37Rv MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
Mb3157c|M.bovis_AF2122/97 MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
MMAR_1516|M.marinum_M MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSEAMARIPAANPDV
MUL_2423|M.ulcerans_Agy99 MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSEAMARIPAANPDV
Mflv_3847|M.gilvum_PYR-GCK MVKVFLVDDHEVVRRGLIDLLGSDPELDVVGEAGSVSEALTRVPTAQPDV
Mvan_2548|M.vanbaalenii_PYR-1 MVKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAEALARIPALQPDV
MSMEG_5244|M.smegmatis_MC2_155 MIRVFLVDDHEVVRRGLIDLLSADPELDVIGEADSVSQALARIPAAQPDV
TH_2159|M.thermoresistible__bu MVSVFLVDDHEVVRRGLIDLLDSDPDLEVVGEAGTVAQAMARIPAAQPDV
MAV_4109|M.avium_104 MVKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAEAKARIPAARPDV
MAB_3891c|M.abscessus_ATCC_199 MITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAEAMARIPALQPDI
MLBr_00174|M.leprae_Br4923 -MRILAVDDDRAVRESLRRSLSFNG--YSVELANDGVEALEMVARDRPDA
: :: ***...**..* * : : *. :* :. .**
Rv3133c|M.tuberculosis_H37Rv AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
Mb3157c|M.bovis_AF2122/97 AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
MMAR_1516|M.marinum_M AVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAILAGASG
MUL_2423|M.ulcerans_Agy99 AVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAILAGASG
Mflv_3847|M.gilvum_PYR-GCK AVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAILAGASG
Mvan_2548|M.vanbaalenii_PYR-1 AVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAILAGASG
MSMEG_5244|M.smegmatis_MC2_155 AVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAILAGASG
TH_2159|M.thermoresistible__bu AVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAILAGASG
MAV_4109|M.avium_104 AVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAILAGASG
MAB_3891c|M.abscessus_ATCC_199 AVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIMAGAGG
MLBr_00174|M.leprae_Br4923 LVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADD
***: :* :*:*:**:* : :* *:**: . : .: ***..
Rv3133c|M.tuberculosis_H37Rv YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
Mb3157c|M.bovis_AF2122/97 YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
MMAR_1516|M.marinum_M YVVKDIKGMELARAIKEVGAGRSLLDNRAAAAL------MSRLRGVVERP
MUL_2423|M.ulcerans_Agy99 YVVKDIKGMELARAIKEVGAGRSLLDNRAAAAL------MSRLRGVVERP
Mflv_3847|M.gilvum_PYR-GCK YVVKDIKGMELARAIKEVGSGRSLLDNRAAAAL------MAKLRGEGERT
Mvan_2548|M.vanbaalenii_PYR-1 YVVKDIKGMELAQAIKDVGSGRSLLDNRAAAAL------MARLRGEGERT
MSMEG_5244|M.smegmatis_MC2_155 YVVKDIKGMELAQAIKDVGAGKSLLDNRAATAL------MSKLRGDAERS
TH_2159|M.thermoresistible__bu YVVKDIKGMELAQAIKDVGAGRSLLDNRAAEAL------MAKLRGADHQP
MAV_4109|M.avium_104 FVIKDIKGMELARAIKDVGAGKSLLDNRAAAAL------MAKLRGSAAQA
MAB_3891c|M.abscessus_ATCC_199 YVIKDIKGMELISAVRTVGAGRSLLDNRAAAAL------MNRLRAAADNP
MLBr_00174|M.leprae_Br4923 YLPKPFALEELLARIRALLRRTKPDDAAESVAMSFSDLTLDPVTREVARG
:: * : ** :: : . * : *: : : .
Rv3133c|M.tuberculosis_H37Rv DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
Mb3157c|M.bovis_AF2122/97 DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
MMAR_1516|M.marinum_M DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
MUL_2423|M.ulcerans_Agy99 DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
Mflv_3847|M.gilvum_PYR-GCK DPLSGLTDQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
Mvan_2548|M.vanbaalenii_PYR-1 DPLSGLTEQERVLLGLLGEG----LTNKQIAARMF-----LAEKTVKNYV
MSMEG_5244|M.smegmatis_MC2_155 DPLSGLTQQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
TH_2159|M.thermoresistible__bu DPLAGLSDQERVLLSLIGEG----LTNKQIAARMF-----LAEKTVKNYV
MAV_4109|M.avium_104 DPLSGLTEQERTLLGLLSEG----LTNRQIAARMF-----LAEKTVKNYV
MAB_3891c|M.abscessus_ATCC_199 SPLAGLTAQERTLLELIGEG----LTNRQIAERMF-----LAEKTVKNYV
MLBr_00174|M.leprae_Br4923 QRWISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYV
. .*: * .** :: . **. :* .:: : :::: **
Rv3133c|M.tuberculosis_H37Rv SRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
Mb3157c|M.bovis_AF2122/97 SRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
MMAR_1516|M.marinum_M SRLLAKLGMERRTQAAVFAAELKRARSAGHR------
MUL_2423|M.ulcerans_Agy99 SRLLAKLGMERRTQAAVFAAELKRARSAGHR------
Mflv_3847|M.gilvum_PYR-GCK SRLLAKLGMERRTQAAVFISKLDRGHGAGNA------
Mvan_2548|M.vanbaalenii_PYR-1 SRLLAKLGMERRTQAAVFVSKLERHHRPDGE------
MSMEG_5244|M.smegmatis_MC2_155 SRLLAKLGMERRTQAAVFASKLDRRN-----------
TH_2159|M.thermoresistible__bu SRLLAKLGMERRTQAAVFVSKLDRPIDPRG-------
MAV_4109|M.avium_104 SRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MAB_3891c|M.abscessus_ATCC_199 SRLLTKLDLERRTQVAVLATKLARENQGLHG------
MLBr_00174|M.leprae_Br4923 GYLRRKTEADGESRLIHTVRGVGYVLRETPP------
. * * : .:: :