For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2159 ()

annotation: TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY LUXR/UHPA-FAMILY)
coordinates: 4244960 - 4245607
length: 216

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2159-100% (216)TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY LUXR/UHPA-FAMILY)
M. thermoresistible (build 8)TH_3563-2e-2734.65% (202) PUTATIVE DNA-binding response regulator, LuxR family protein
M. thermoresistible (build 8)TH_3184-4e-2734.48% (203) PUTATIVE two component transcriptional regulator, LuxR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3157cdevR1e-9783.10% (213) two component transcriptional regulatory protein DevR
M. gilvum PYR-GCKMflv_3847-2e-9885.17% (209) two component LuxR family transcriptional regulator
M. tuberculosis H37RvRv3133cdevR1e-9783.10% (213) two component transcriptional regulatory protein DevR
M. leprae Br4923MLBr_00773mtrA2e-0826.00% (150) putative two-component response regulator
M. abscessus ATCC 19977MAB_3891c-9e-8472.25% (209) LuxR family transcriptional regulator
M. marinum MMMAR_1516devR6e-9683.25% (209) two-component transcriptional regulatory protein DevR
M. avium 104MAV_4109-2e-9583.25% (209) two component transcriptional regulatory protein devr
M. smegmatis MC2 155MSMEG_5244-8e-9885.17% (209) two component transcriptional regulatory protein devr
M. ulcerans Agy99MUL_2423devR4e-9683.25% (209) two component transcriptional regulatory protein DevR
M. vanbaalenii PYR-1Mvan_2548-1e-10085.58% (215) two component LuxR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3847|M.gilvum_PYR-GCK          ----MVKVFLVDDHEVVRRGLIDLLGSD-PELDVVGEAGSVSEALTRVPT
Mvan_2548|M.vanbaalenii_PYR-1       ----MVKVFLVDDHEVVRRGLIDLLSSD-PELDVVGEAGSVAEALARIPA
MSMEG_5244|M.smegmatis_MC2_155      ----MIRVFLVDDHEVVRRGLIDLLSAD-PELDVIGEADSVSQALARIPA
TH_2159|M.thermoresistible__bu      ----MVSVFLVDDHEVVRRGLIDLLDSD-PDLEVVGEAGTVAQAMARIPA
Mb3157c|M.bovis_AF2122/97           ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
Rv3133c|M.tuberculosis_H37Rv        ----MVKVFLVDDHEVVRRGLVDLLGAD-PELDVVGEAGSVAEAMARVPA
MMAR_1516|M.marinum_M               ----MVTVFLVDDHEVVRRGLIDLLDAD-PQLDVVGEAGSVSEAMARIPA
MUL_2423|M.ulcerans_Agy99           ----MVTVFLVDDHEVVRRGLIDLLDAD-PQLDVVGEAGSVSEAMARIPA
MAV_4109|M.avium_104                ----MVKVFLVDDHEVVRRGLCDLLSSD-PDLRIVGEAGTVAEAKARIPA
MAB_3891c|M.abscessus_ATCC_199      ----MITVFLVDDHEVVRRGLADLLEEE-ADFSVIGQASSVAEAMARIPA
MLBr_00773|M.leprae_Br4923          MDIMRQRILVVDDDASLAEMLTIVLRGEGFDTAVIGDG---TQALTAVRE
                                           :::***.  : . *  :*  :  :  ::*:.   ::* : :  

Mflv_3847|M.gilvum_PYR-GCK          AQPDVAVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAIL
Mvan_2548|M.vanbaalenii_PYR-1       LQPDVAVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAIL
MSMEG_5244|M.smegmatis_MC2_155      AQPDVAVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAIL
TH_2159|M.thermoresistible__bu      AQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAIL
Mb3157c|M.bovis_AF2122/97           ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
Rv3133c|M.tuberculosis_H37Rv        ARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAIL
MMAR_1516|M.marinum_M               ANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAIL
MUL_2423|M.ulcerans_Agy99           ANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAIL
MAV_4109|M.avium_104                ARPDVAVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAIL
MAB_3891c|M.abscessus_ATCC_199      LQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIM
MLBr_00773|M.leprae_Br4923          LRPDLVLLDLMLPGMNGIDVCRVLRADS-GVPIVMLTAKTDTVDVVLGLE
                                     .**:.:**: **. :*:::** * :   .:  ::**: *.   :: .: 

Mflv_3847|M.gilvum_PYR-GCK          AGASGYVVKDIKGMELARAIKEVGSGR----SLLDNRAAAALMAKLRGEG
Mvan_2548|M.vanbaalenii_PYR-1       AGASGYVVKDIKGMELAQAIKDVGSGR----SLLDNRAAAALMARLRGEG
MSMEG_5244|M.smegmatis_MC2_155      AGASGYVVKDIKGMELAQAIKDVGAGK----SLLDNRAATALMSKLRGDA
TH_2159|M.thermoresistible__bu      AGASGYVVKDIKGMELAQAIKDVGAGR----SLLDNRAAEALMAKLRGAD
Mb3157c|M.bovis_AF2122/97           AGASGYVVKDIKGMELARAVKDVGAGR----SLLDNRAAAALMAKLRGAA
Rv3133c|M.tuberculosis_H37Rv        AGASGYVVKDIKGMELARAVKDVGAGR----SLLDNRAAAALMAKLRGAA
MMAR_1516|M.marinum_M               AGASGYVVKDIKGMELARAIKEVGAGR----SLLDNRAAAALMSRLRGVV
MUL_2423|M.ulcerans_Agy99           AGASGYVVKDIKGMELARAIKEVGAGR----SLLDNRAAAALMSRLRGVV
MAV_4109|M.avium_104                AGASGFVIKDIKGMELARAIKDVGAGK----SLLDNRAAAALMAKLRGSA
MAB_3891c|M.abscessus_ATCC_199      AGAGGYVIKDIKGMELISAVRTVGAGR----SLLDNRAAAALMNRLRAAA
MLBr_00773|M.leprae_Br4923          SGADDYIMKPFKPKELVARVRARLRRNDDEPAEMLSIADVDIDVPAHKVT
                                    :**..:::* :*  **   ::     .    : : . *   :    :   

Mflv_3847|M.gilvum_PYR-GCK          ERTDPLSGLTDQERVLLDLLGEG---------LTNKQIAARMFLAEKTVK
Mvan_2548|M.vanbaalenii_PYR-1       ERTDPLSGLTEQERVLLGLLGEG---------LTNKQIAARMFLAEKTVK
MSMEG_5244|M.smegmatis_MC2_155      ERSDPLSGLTQQERVLLDLLGEG---------LTNKQIAARMFLAEKTVK
TH_2159|M.thermoresistible__bu      HQPDPLAGLSDQERVLLSLIGEG---------LTNKQIAARMFLAEKTVK
Mb3157c|M.bovis_AF2122/97           EKQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
Rv3133c|M.tuberculosis_H37Rv        EKQDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MMAR_1516|M.marinum_M               ERPDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MUL_2423|M.ulcerans_Agy99           ERPDPLSGLTDQERTLLGLLSEG---------LTNKQIADRMFLAEKTVK
MAV_4109|M.avium_104                AQADPLSGLTEQERTLLGLLSEG---------LTNRQIAARMFLAEKTVK
MAB_3891c|M.abscessus_ATCC_199      DNPSPLAGLTAQERTLLELIGEG---------LTNRQIAERMFLAEKTVK
MLBr_00773|M.leprae_Br4923          RNGEHIS-LTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVN
                                     . . :: *:  *  **  :..          * ::  . *     : *:

Mflv_3847|M.gilvum_PYR-GCK          NYVSRLLAKLGMERRTQAAVFISKLDRGHGAGNA------
Mvan_2548|M.vanbaalenii_PYR-1       NYVSRLLAKLGMERRTQAAVFVSKLERHHRPDGE------
MSMEG_5244|M.smegmatis_MC2_155      NYVSRLLAKLGMERRTQAAVFASKLDRRN-----------
TH_2159|M.thermoresistible__bu      NYVSRLLAKLGMERRTQAAVFVSKLDRPIDPRG-------
Mb3157c|M.bovis_AF2122/97           NYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
Rv3133c|M.tuberculosis_H37Rv        NYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP-----
MMAR_1516|M.marinum_M               NYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR------
MUL_2423|M.ulcerans_Agy99           NYVSRLLAKLGMERRTQAAVFAAELKRARSAGHR------
MAV_4109|M.avium_104                NYVSRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MAB_3891c|M.abscessus_ATCC_199      NYVSRLLTKLDLERRTQVAVLATKLARENQGLHG------
MLBr_00773|M.leprae_Br4923          VHVQRLRAKVEKDPENPTVVLTVRGVGYKAGPP-------
                                     :*.** :*:  : .. ..*:  .