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VKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAEALARIPALQPDVAVLDVRLPDGNGIELCRDLLS RLPDLRCLMLTSFTSDEAMLDAILAGASGYVVKDIKGMELAQAIKDVGSGRSLLDNRAAAALMARLRGEG ERTDPLSGLTEQERVLLGLLGEGLTNKQIAARMFLAEKTVKNYVSRLLAKLGMERRTQAAVFVSKLERHH RPDGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2548 | - | - | 100% (216) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1427 | - | e-100 | 87.74% (212) | two component LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5474 | - | 1e-36 | 39.42% (208) | two component LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 1e-101 | 85.65% (216) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 1e-105 | 91.94% (211) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 1e-101 | 85.65% (216) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_01286 | - | 2e-09 | 31.68% (161) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_3891c | - | 2e-84 | 71.70% (212) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_3480 | - | 1e-100 | 86.38% (213) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_4109 | - | 8e-98 | 86.60% (209) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 1e-102 | 88.15% (211) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 1e-100 | 85.58% (215) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 1e-97 | 86.12% (209) | two component transcriptional regulatory protein DevR |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2548|M.vanbaalenii_PYR-1 ------------MVKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAE
Mflv_3847|M.gilvum_PYR-GCK ------------MVKVFLVDDHEVVRRGLIDLLGSDPELDVVGEAGSVSE
MSMEG_5244|M.smegmatis_MC2_155 ------------MIRVFLVDDHEVVRRGLIDLLSADPELDVIGEADSVSQ
Mb3157c|M.bovis_AF2122/97 ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
Rv3133c|M.tuberculosis_H37Rv ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
MUL_2423|M.ulcerans_Agy99 ------------MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSE
MMAR_3480|M.marinum_M ------------MVKVFLVDDHEVVRRGLVDLLGSDPDLEIIGEAGSVSE
MAV_4109|M.avium_104 ------------MVKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAE
TH_2159|M.thermoresistible__bu ------------MVSVFLVDDHEVVRRGLIDLLDSDPDLEVVGEAGTVAQ
MAB_3891c|M.abscessus_ATCC_199 ------------MITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAE
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLR-DEGYDIVGEAADGQE
*::.:*. ::* .* ::* : ::*:* :
Mvan_2548|M.vanbaalenii_PYR-1 ALARIPALQPDVAVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDE
Mflv_3847|M.gilvum_PYR-GCK ALTRVPTAQPDVAVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDE
MSMEG_5244|M.smegmatis_MC2_155 ALARIPAAQPDVAVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDE
Mb3157c|M.bovis_AF2122/97 AMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDE
Rv3133c|M.tuberculosis_H37Rv AMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDE
MUL_2423|M.ulcerans_Agy99 AMARIPAANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDE
MMAR_3480|M.marinum_M AMARIPALQPDVAVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSDE
MAV_4109|M.avium_104 AKARIPAARPDVAVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDE
TH_2159|M.thermoresistible__bu AMARIPAAQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQ
MAB_3891c|M.abscessus_ATCC_199 AMARIPALQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEH
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD
* .**:.::*:::* :*:: . :: : ::**:::. .
Mvan_2548|M.vanbaalenii_PYR-1 AMLDAILAGASGYVVKDIKGMELAQAIKDVGSGRSLLDNRAAAALMARLR
Mflv_3847|M.gilvum_PYR-GCK AMLDAILAGASGYVVKDIKGMELARAIKEVGSGRSLLDNRAAAALMAKLR
MSMEG_5244|M.smegmatis_MC2_155 AMLDAILAGASGYVVKDIKGMELAQAIKDVGAGKSLLDNRAATALMSKLR
Mb3157c|M.bovis_AF2122/97 AMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR
Rv3133c|M.tuberculosis_H37Rv AMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR
MUL_2423|M.ulcerans_Agy99 AMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLR
MMAR_3480|M.marinum_M AMLEAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLR
MAV_4109|M.avium_104 AMLEAILAGASGFVIKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLR
TH_2159|M.thermoresistible__bu AMLDAILAGASGYVVKDIKGMELAQAIKDVGAGRSLLDNRAAEALMAKLR
MAB_3891c|M.abscessus_ATCC_199 AMLDAIMAGAGGYVIKDIKGMELISAVRTVGAGRSLLDNRAAAALMNRLR
MLBr_01286|M.leprae_Br4923 LVERARDAGAMAYLVKPFT----------------------ISDLIPAIA
: * *** .:::* :. *: :
Mvan_2548|M.vanbaalenii_PYR-1 GEGERTDPLSGLTEQERVLLGLLGEGLTNKQIAARMFLAEKTVKNYVSRL
Mflv_3847|M.gilvum_PYR-GCK GEGERTDPLSGLTDQERVLLDLLGEGLTNKQIAARMFLAEKTVKNYVSRL
MSMEG_5244|M.smegmatis_MC2_155 GDAERSDPLSGLTQQERVLLDLLGEGLTNKQIAARMFLAEKTVKNYVSRL
Mb3157c|M.bovis_AF2122/97 GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
Rv3133c|M.tuberculosis_H37Rv GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
MUL_2423|M.ulcerans_Agy99 GVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
MMAR_3480|M.marinum_M GGAEQKDPLSGLTEQERTLLGHLSEGLTNRQIAARMFLAEKTVKNYVSRL
MAV_4109|M.avium_104 GSAAQADPLSGLTEQERTLLGLLSEGLTNRQIAARMFLAEKTVKNYVSRL
TH_2159|M.thermoresistible__bu GADHQPDPLAGLSDQERVLLSLIGEGLTNKQIAARMFLAEKTVKNYVSRL
MAB_3891c|M.abscessus_ATCC_199 AAADNPSPLAGLTAQERTLLELIGEGLTNRQIAERMFLAEKTVKNYVSRL
MLBr_01286|M.leprae_Br4923 LAMSRFSELTALEREVATLADRLETRKLVERAKGLLQVKQGMTEPEAFKW
. . *:.* : .* : .: : : : .: . :
Mvan_2548|M.vanbaalenii_PYR-1 LAKLGMERRTQAAVFVSKLER--HHRPDGE----
Mflv_3847|M.gilvum_PYR-GCK LAKLGMERRTQAAVFISKLDR--GHGAGNA----
MSMEG_5244|M.smegmatis_MC2_155 LAKLGMERRTQAAVFASKLDR--RN---------
Mb3157c|M.bovis_AF2122/97 LAKLGMERRTQAAVFATELKR--SRPPGDGP---
Rv3133c|M.tuberculosis_H37Rv LAKLGMERRTQAAVFATELKR--SRPPGDGP---
MUL_2423|M.ulcerans_Agy99 LAKLGMERRTQAAVFAAELKR--ARSAGHR----
MMAR_3480|M.marinum_M LAKLGMERRTQAAVFASRLGQ--GTRPVQGD---
MAV_4109|M.avium_104 LAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
TH_2159|M.thermoresistible__bu LAKLGMERRTQAAVFVSKLDR--PIDPRG-----
MAB_3891c|M.abscessus_ATCC_199 LTKLDLERRTQVAVLATKLAR--ENQGLHG----
MLBr_01286|M.leprae_Br4923 IQRAAMDRRTTMKRVAEVVLETLDTPKDT-----
: : ::*** . : .