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M. avium 104 MAV_4109 (-)

annotation: two component transcriptional regulatory protein devr
coordinates: 4231757 - 4232425
length: 222

VKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAEAKARIPAARPDVAVLDVRLPDGNGIELCRDLLS
EHPDLRCLMLTSFTSDEAMLEAILAGASGFVIKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLRGSA
AQADPLSGLTEQERTLLGLLSEGLTNRQIAARMFLAEKTVKNYVSRLLAKLGMERRTQAAVFASKLNQQA
GRPPTPPDWPG*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_4109 - - 100% (222) two component transcriptional regulatory protein devr
M. avium 104 MAV_5280 - 4e-29 36.59% (205) two-component system response regulator
M. avium 104 MAV_4114 - 2e-26 32.35% (204) response regulator receiver domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3157c devR 9e-99 84.65% (215) two component transcriptional regulatory protein DevR
M. gilvum PYR-GCK Mflv_3847 - 3e-95 83.02% (212) two component LuxR family transcriptional regulator
M. tuberculosis H37Rv Rv3133c devR 9e-99 84.65% (215) two component transcriptional regulatory protein DevR
M. leprae Br4923 MLBr_00174 - 6e-09 34.78% (115) putative two-component response regulator
M. abscessus ATCC 19977 MAB_3891c - 4e-81 70.48% (210) LuxR family transcriptional regulator
M. marinum M MMAR_3480 - 1e-101 90.43% (209) two-component transcriptional regulatory protein
M. smegmatis MC2 155 MSMEG_5244 - 1e-95 83.33% (210) two component transcriptional regulatory protein devr
M. thermoresistible (build 8) TH_2159 - 2e-95 83.25% (209) TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY
M. ulcerans Agy99 MUL_2423 devR 2e-93 82.30% (209) two component transcriptional regulatory protein DevR
M. vanbaalenii PYR-1 Mvan_2548 - 1e-97 86.60% (209) two component LuxR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MAV_4109|M.avium_104                MVKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAEAKARIPAARPDV
MMAR_3480|M.marinum_M               MVKVFLVDDHEVVRRGLVDLLGSDPDLEIIGEAGSVSEAMARIPALQPDV
Mb3157c|M.bovis_AF2122/97           MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
Rv3133c|M.tuberculosis_H37Rv        MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAEAMARVPAARPDV
MUL_2423|M.ulcerans_Agy99           MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSEAMARIPAANPDV
Mflv_3847|M.gilvum_PYR-GCK          MVKVFLVDDHEVVRRGLIDLLGSDPELDVVGEAGSVSEALTRVPTAQPDV
Mvan_2548|M.vanbaalenii_PYR-1       MVKVFLVDDHEVVRRGLIDLLSSDPELDVVGEAGSVAEALARIPALQPDV
MSMEG_5244|M.smegmatis_MC2_155      MIRVFLVDDHEVVRRGLIDLLSADPELDVIGEADSVSQALARIPAAQPDV
TH_2159|M.thermoresistible__bu      MVSVFLVDDHEVVRRGLIDLLDSDPDLEVVGEAGTVAQAMARIPAAQPDV
MAB_3891c|M.abscessus_ATCC_199      MITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAEAMARIPALQPDI
MLBr_00174|M.leprae_Br4923          -MRILAVDDDRAVRESLRRSLSFNG--YSVELANDGVEALEMVARDRPDA
                                     : :: ***...**..*   *  :     :  *.   :*   :.  .** 

MAV_4109|M.avium_104                AVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDEAMLEAILAGASG
MMAR_3480|M.marinum_M               AVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSDEAMLEAILAGASG
Mb3157c|M.bovis_AF2122/97           AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
Rv3133c|M.tuberculosis_H37Rv        AVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDEAMLDAILAGASG
MUL_2423|M.ulcerans_Agy99           AVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDEAMLDAILAGASG
Mflv_3847|M.gilvum_PYR-GCK          AVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDEAMLDAILAGASG
Mvan_2548|M.vanbaalenii_PYR-1       AVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDEAMLDAILAGASG
MSMEG_5244|M.smegmatis_MC2_155      AVLDVRLPDGNGIELCRDLLSHMPNLRCLMLTSFTSDEAMLDAILAGASG
TH_2159|M.thermoresistible__bu      AVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQAMLDAILAGASG
MAB_3891c|M.abscessus_ATCC_199      AVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEHAMLDAIMAGAGG
MLBr_00174|M.leprae_Br4923          LVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADD
                                     ***: :*  :*:*:**:* :   :*  *:**:  .    : .: ***..

MAV_4109|M.avium_104                FVIKDIKGMELARAIKDVGAGKSLLDNRAAAAL------MAKLRGSAAQA
MMAR_3480|M.marinum_M               YVVKDIKGMELARAIKDVGAGKSLLDNRAAAAL------MAKLRGGAEQK
Mb3157c|M.bovis_AF2122/97           YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
Rv3133c|M.tuberculosis_H37Rv        YVVKDIKGMELARAVKDVGAGRSLLDNRAAAAL------MAKLRGAAEKQ
MUL_2423|M.ulcerans_Agy99           YVVKDIKGMELARAIKEVGAGRSLLDNRAAAAL------MSRLRGVVERP
Mflv_3847|M.gilvum_PYR-GCK          YVVKDIKGMELARAIKEVGSGRSLLDNRAAAAL------MAKLRGEGERT
Mvan_2548|M.vanbaalenii_PYR-1       YVVKDIKGMELAQAIKDVGSGRSLLDNRAAAAL------MARLRGEGERT
MSMEG_5244|M.smegmatis_MC2_155      YVVKDIKGMELAQAIKDVGAGKSLLDNRAATAL------MSKLRGDAERS
TH_2159|M.thermoresistible__bu      YVVKDIKGMELAQAIKDVGAGRSLLDNRAAEAL------MAKLRGADHQP
MAB_3891c|M.abscessus_ATCC_199      YVIKDIKGMELISAVRTVGAGRSLLDNRAAAAL------MNRLRAAADNP
MLBr_00174|M.leprae_Br4923          YLPKPFALEELLARIRALLRRTKPDDAAESVAMSFSDLTLDPVTREVARG
                                    :: * :   **   :: :    .  *   : *:      :  :     . 

MAV_4109|M.avium_104                DPLSGLTEQERTLLGLLSEG----LTNRQIAARMF-----LAEKTVKNYV
MMAR_3480|M.marinum_M               DPLSGLTEQERTLLGHLSEG----LTNRQIAARMF-----LAEKTVKNYV
Mb3157c|M.bovis_AF2122/97           DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
Rv3133c|M.tuberculosis_H37Rv        DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
MUL_2423|M.ulcerans_Agy99           DPLSGLTDQERTLLGLLSEG----LTNKQIADRMF-----LAEKTVKNYV
Mflv_3847|M.gilvum_PYR-GCK          DPLSGLTDQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
Mvan_2548|M.vanbaalenii_PYR-1       DPLSGLTEQERVLLGLLGEG----LTNKQIAARMF-----LAEKTVKNYV
MSMEG_5244|M.smegmatis_MC2_155      DPLSGLTQQERVLLDLLGEG----LTNKQIAARMF-----LAEKTVKNYV
TH_2159|M.thermoresistible__bu      DPLAGLSDQERVLLSLIGEG----LTNKQIAARMF-----LAEKTVKNYV
MAB_3891c|M.abscessus_ATCC_199      SPLAGLTAQERTLLELIGEG----LTNRQIAERMF-----LAEKTVKNYV
MLBr_00174|M.leprae_Br4923          QRWISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYV
                                    .   .*:  * .**  :  .    **. :*  .::      : :::: **

MAV_4109|M.avium_104                SRLLAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MMAR_3480|M.marinum_M               SRLLAKLGMERRTQAAVFASRLGQ--GTRPVQGD---
Mb3157c|M.bovis_AF2122/97           SRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
Rv3133c|M.tuberculosis_H37Rv        SRLLAKLGMERRTQAAVFATELKR--SRPPGDGP---
MUL_2423|M.ulcerans_Agy99           SRLLAKLGMERRTQAAVFAAELKR--ARSAGHR----
Mflv_3847|M.gilvum_PYR-GCK          SRLLAKLGMERRTQAAVFISKLDR--GHGAGNA----
Mvan_2548|M.vanbaalenii_PYR-1       SRLLAKLGMERRTQAAVFVSKLER--HHRPDGE----
MSMEG_5244|M.smegmatis_MC2_155      SRLLAKLGMERRTQAAVFASKLDR--RN---------
TH_2159|M.thermoresistible__bu      SRLLAKLGMERRTQAAVFVSKLDR--PIDPRG-----
MAB_3891c|M.abscessus_ATCC_199      SRLLTKLDLERRTQVAVLATKLAR--ENQGLHG----
MLBr_00174|M.leprae_Br4923          GYLRRKTEADGESRLIHTVRGVGYVLRETPP------
                                    . *  *   : .::       :

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_4109	-	-	100% (222)	two component transcriptional regulatory protein devr
M. avium 104	MAV_5280	-	4e-29	36.59% (205)	two-component system response regulator
M. avium 104	MAV_4114	-	2e-26	32.35% (204)	response regulator receiver domain-containing protein