For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MVTVFLVDDHELVRRGLIDLVRSDPDLDVIGEAGSVSEAMARIPALRPEVAVLDVRLPDGNGIELCRDLL SRLPDLRCLMLTSFTSDEATLDAILAGASGFVIKDIKGMDLTHAIKEVAAGHSLLDNRAAAALMKRLRET ASHSDPLTGLSDQERMLLELLGEGLTNKQIAERMFLAERTVKNYVSRLLAKLGMERRTQAAVFISKLDHG RHHDEQY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3944 | - | - | 100% (217) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_5244 | - | 2e-91 | 80.77% (208) | two component transcriptional regulatory protein devr |
| M. smegmatis MC2 155 | MSMEG_6236 | - | 7e-38 | 38.46% (208) | two-component system, regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 2e-91 | 78.20% (211) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_3847 | - | 2e-93 | 80.95% (210) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3133c | devR | 2e-91 | 78.20% (211) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | MLBr_01286 | - | 1e-09 | 28.30% (159) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_3891c | - | 1e-81 | 71.50% (207) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_1516 | devR | 4e-91 | 79.62% (211) | two-component transcriptional regulatory protein DevR |
| M. avium 104 | MAV_4109 | - | 1e-89 | 80.29% (208) | two component transcriptional regulatory protein devr |
| M. thermoresistible (build 8) | TH_2159 | - | 3e-92 | 79.81% (208) | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY |
| M. ulcerans Agy99 | MUL_2423 | devR | 3e-91 | 79.62% (211) | two component transcriptional regulatory protein DevR |
| M. vanbaalenii PYR-1 | Mvan_1427 | - | 3e-95 | 83.65% (208) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3944|M.smegmatis_MC2_155 ------------MVTVFLVDDHELVRRGLIDLVRSDPDLDVIGEAGSVSE
Mvan_1427|M.vanbaalenii_PYR-1 ------------MVRVFLVDDHEVVRRGLIDLLSTDPELDVVGEAGSVSE
Mb3157c|M.bovis_AF2122/97 ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
Rv3133c|M.tuberculosis_H37Rv ------------MVKVFLVDDHEVVRRGLVDLLGADPELDVVGEAGSVAE
MMAR_1516|M.marinum_M ------------MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSE
MUL_2423|M.ulcerans_Agy99 ------------MVTVFLVDDHEVVRRGLIDLLDADPQLDVVGEAGSVSE
Mflv_3847|M.gilvum_PYR-GCK ------------MVKVFLVDDHEVVRRGLIDLLGSDPELDVVGEAGSVSE
TH_2159|M.thermoresistible__bu ------------MVSVFLVDDHEVVRRGLIDLLDSDPDLEVVGEAGTVAQ
MAV_4109|M.avium_104 ------------MVKVFLVDDHEVVRRGLCDLLSSDPDLRIVGEAGTVAE
MAB_3891c|M.abscessus_ATCC_199 ------------MITVFLVDDHEVVRRGLADLLEEEADFSVIGQASSVAE
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLR-DEGYDIVGEAADGQE
*::.:*. ::* .* ::: : ::*:*. :
MSMEG_3944|M.smegmatis_MC2_155 AMARIPALRPEVAVLDVRLPDGNGIELCRDLLSRLPDLRCLMLTSFTSDE
Mvan_1427|M.vanbaalenii_PYR-1 ALTRIPAVAPEVAVLDVRLPDGNGIELCRDLLSRVPGLRCLMLTSFTSDE
Mb3157c|M.bovis_AF2122/97 AMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDE
Rv3133c|M.tuberculosis_H37Rv AMARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTSYTSDE
MMAR_1516|M.marinum_M AMARIPAANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDE
MUL_2423|M.ulcerans_Agy99 AMARIPAANPDVAVLDVRLPDGDGIELCRDLLSRMPNLRCLILTSYTSDE
Mflv_3847|M.gilvum_PYR-GCK ALTRVPTAQPDVAVLDVRLPDGNGIELCRELLSLMPDLRCLMLTSFTSDE
TH_2159|M.thermoresistible__bu AMARIPAAQPDVAVLDVRLPDGNGVELCRDLLARMPDLRCLMLTSYTSDQ
MAV_4109|M.avium_104 AKARIPAARPDVAVLDVRLPDGNGIELCRDLLSEHPDLRCLMLTSFTSDE
MAB_3891c|M.abscessus_ATCC_199 AMARIPALQPDIAVLDIRLPDGNGVELCRELRSKLPNLNCLMLTSFTDEH
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD
* *::.::*:::* :*:: . :: : ::**:::. .
MSMEG_3944|M.smegmatis_MC2_155 ATLDAILAGASGFVIKDIKGMDLTHAIKEVAAGHSLLDNRAAAALMKRLR
Mvan_1427|M.vanbaalenii_PYR-1 AMLDAILAGASGYVIKDIKGMELAEAIKDVGAGRSLLDNRAAAALMSRLR
Mb3157c|M.bovis_AF2122/97 AMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR
Rv3133c|M.tuberculosis_H37Rv AMLDAILAGASGYVVKDIKGMELARAVKDVGAGRSLLDNRAAAALMAKLR
MMAR_1516|M.marinum_M AMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLR
MUL_2423|M.ulcerans_Agy99 AMLDAILAGASGYVVKDIKGMELARAIKEVGAGRSLLDNRAAAALMSRLR
Mflv_3847|M.gilvum_PYR-GCK AMLDAILAGASGYVVKDIKGMELARAIKEVGSGRSLLDNRAAAALMAKLR
TH_2159|M.thermoresistible__bu AMLDAILAGASGYVVKDIKGMELAQAIKDVGAGRSLLDNRAAEALMAKLR
MAV_4109|M.avium_104 AMLEAILAGASGFVIKDIKGMELARAIKDVGAGKSLLDNRAAAALMAKLR
MAB_3891c|M.abscessus_ATCC_199 AMLDAIMAGAGGYVIKDIKGMELISAVRTVGAGRSLLDNRAAAALMNRLR
MLBr_01286|M.leprae_Br4923 LVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----ALEREVA
* *** .:::* :. :* *: . : * * ** .:
MSMEG_3944|M.smegmatis_MC2_155 ETASHSDPLTGLSDQERMLLELLGEGLTNKQIAERMFLAERTVKNYVSRL
Mvan_1427|M.vanbaalenii_PYR-1 DTAERADPLLGLSSQERVLLDLLGEGLTNKQIADRMFLAEKTVKNYVSRL
Mb3157c|M.bovis_AF2122/97 GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
Rv3133c|M.tuberculosis_H37Rv GAAEKQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
MMAR_1516|M.marinum_M GVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
MUL_2423|M.ulcerans_Agy99 GVVERPDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTVKNYVSRL
Mflv_3847|M.gilvum_PYR-GCK GEGERTDPLSGLTDQERVLLDLLGEGLTNKQIAARMFLAEKTVKNYVSRL
TH_2159|M.thermoresistible__bu GADHQPDPLAGLSDQERVLLSLIGEGLTNKQIAARMFLAEKTVKNYVSRL
MAV_4109|M.avium_104 GSAAQADPLSGLTEQERTLLGLLSEGLTNRQIAARMFLAEKTVKNYVSRL
MAB_3891c|M.abscessus_ATCC_199 AAADNPSPLAGLTAQERTLLELIGEGLTNRQIAERMFLAEKTVKNYVSRL
MLBr_01286|M.leprae_Br4923 TLADRLETRK-LVERAKGLLQVKQG------------MTEPEAFKWIQRA
. .. * : : ** : ::* . :::.*
MSMEG_3944|M.smegmatis_MC2_155 LAKLGMERRTQAAVFISKLD----HGRHHDEQY-
Mvan_1427|M.vanbaalenii_PYR-1 LAKLGMERRTQAAVFVSRLD----RAGR------
Mb3157c|M.bovis_AF2122/97 LAKLGMERRTQAAVFATELK----RSRPPGDGP-
Rv3133c|M.tuberculosis_H37Rv LAKLGMERRTQAAVFATELK----RSRPPGDGP-
MMAR_1516|M.marinum_M LAKLGMERRTQAAVFAAELK----RARSAGHR--
MUL_2423|M.ulcerans_Agy99 LAKLGMERRTQAAVFAAELK----RARSAGHR--
Mflv_3847|M.gilvum_PYR-GCK LAKLGMERRTQAAVFISKLD----RGHGAGNA--
TH_2159|M.thermoresistible__bu LAKLGMERRTQAAVFVSKLD----RPIDPRG---
MAV_4109|M.avium_104 LAKLGMERRTQAAVFASKLNQQAGRPPTPPDWPG
MAB_3891c|M.abscessus_ATCC_199 LTKLDLERRTQVAVLATKLA----RENQGLHG--
MLBr_01286|M.leprae_Br4923 AMDRRTTMKRVAEVVLETLD----TPKDT-----
. : . *. *