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TPRSLVRIVGVVVATTLALVSAPAGGRAAHADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRS IGVYAVNYPASDDYRASASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSAMPPAVADHVAA VALFGEPSSGFSSMLWGGGSLPTIGPLYSSKTINLCAPDDPICTGGGNIMAHVSYVQSGMTSQAATFAAN RLDHAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | - | 100% (217) | PROBABLE CUTINASE PRECURSOR CFP21 |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 1e-45 | 48.37% (215) | cutinase precursor CUT4 |
| M. tuberculosis H37Rv | Rv3451 | cut3 | 6e-42 | 47.00% (217) | cutinase precursor CUT3 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2006c | cfp21 | 1e-122 | 100.00% (217) | cutinase precursor CFP21 |
| M. gilvum PYR-GCK | Mflv_3373 | - | 2e-50 | 46.88% (224) | cutinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3272c | - | 7e-41 | 46.84% (190) | cutinase Cut1 |
| M. marinum M | MMAR_2934 | cfp21 | 6e-91 | 75.70% (214) | cutinase Cfp21 |
| M. avium 104 | MAV_2741 | - | 6e-86 | 77.25% (189) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_2474 | - | 6e-46 | 45.19% (239) | cutinase Cut3 |
| M. thermoresistible (build 8) | TH_1243 | - | 8e-46 | 43.72% (247) | PROBABLE CUTINASE |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 2e-45 | 46.43% (224) | cutinase, Cut5 |
| M. vanbaalenii PYR-1 | Mvan_3105 | - | 1e-54 | 50.89% (224) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1984c|M.tuberculosis_H37Rv --------------------------MTPRSLVRIVGVVVATTLALVSAP
Mb2006c|M.bovis_AF2122/97 --------------------------MTPRSLVRIVGVVVATTLALVSAP
MMAR_2934|M.marinum_M --------------------------MIARSFARILGAAVVA-LGVLSAP
MAV_2741|M.avium_104 -----------------------------------MG-------------
TH_1243|M.thermoresistible__bu MGWVDMRVTELPNRSRSMFRLIGVISAFVLAGSMACGIGFVSAVMGVGSP
MUL_4327|M.ulcerans_Agy99 -----MRNATWTRR--------------LAVGAATAVTALVGG--GIRVP
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_2474|M.smegmatis_MC2_155 -----MNNDHATTRPS--------IVRTAFVGVTLAALGLVMGVVGLQAA
Mflv_3373|M.gilvum_PYR-GCK --------------------------MRSKRLRAVAGAVFVATAASVQTV
Mvan_3105|M.vanbaalenii_PYR-1 --------------------------MQVRRVLGIVGAAVAVSAGLWPIG
Rv1984c|M.tuberculosis_H37Rv AGGRAAHADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGV
Mb2006c|M.bovis_AF2122/97 AGGRAAHADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGV
MMAR_2934|M.marinum_M VFSPSATADPCSDVAVVFARGTHQEPGLGNIGQAFVDSLTSQVGGRSVDV
MAV_2741|M.avium_104 --NPVAAADPCSDVSVVFARGTHQEPGLGNIGQAFVDSLTSQLGGRSVDV
TH_1243|M.thermoresistible__bu ----TAAAQPCPDVEVIFARGTDEPPGVGGVGQAFIDELRPRIGDRSLSV
MUL_4327|M.ulcerans_Agy99 ----FVAAEPCPDVEVLFARGTGEPPGIGGIGGSFVAALRSDIGAKSSAV
MAB_3272c|M.abscessus_ATCC_199 ----------------MFARGTFEPPGVGGTGESFVNALRARTKGKSVEV
MSMEG_2474|M.smegmatis_MC2_155 GTASAAPSSPCADVEVVFARGTFEAPGVGDTGQAFVNALGAQLPGKNIAV
Mflv_3373|M.gilvum_PYR-GCK AGTPAAAADPCPDVEVIWARGTGAPAGLGWLGTAFVDSLRAKVGGRSVGA
Mvan_3105|M.vanbaalenii_PYR-1 VGAPAASADPCPDIEVIFARGTGAEPGLGWVGDAFVNALRPKVGGRSVGT
::**** .*:* * :*: * . :. .
Rv1984c|M.tuberculosis_H37Rv YAVNYPASDDYRA------SASNGSDDASAHIQRTVASCPNTRIVLGGYS
Mb2006c|M.bovis_AF2122/97 YAVNYPASDDYRA------SASNGSDDASAHIQRTVASCPNTRIVLGGYS
MMAR_2934|M.marinum_M YAVNYPANDDYHT------SASLGSDDASAHIQGTVANCPNTKIVLGGYS
MAV_2741|M.avium_104 YAVNYPANDDYHN------SANAGADDASAHVQDTVAACPNSRIVLGGYS
TH_1243|M.thermoresistible__bu YAVNYPASSNFGAGIEFARTVVDGIRDAADRVQTTAANCPDTRIVLGGYS
MUL_4327|M.ulcerans_Agy99 YAIDYPASSDFSS-SDFPRTVIDGIRDASSHIESMAAKCPATREVLGGYS
MAB_3272c|M.abscessus_ATCC_199 YPVEYPASLAFAT-------AADGVIDASNRVKDVAARCPNTKIVMGGFS
MSMEG_2474|M.smegmatis_MC2_155 YAVNYPASLDFND-------AALGVADAAREVQAVAAGCPDTQIVLGGYS
Mflv_3373|M.gilvum_PYR-GCK YGVNYPASFDFDA------SAPMGAADAAGRVQWMADNCPDTRLVLGGNS
Mvan_3105|M.vanbaalenii_PYR-1 YAVNYPAGFDFDN------SAPLGAADASGRVQWMAGNCPDTKLVLGGMS
* ::***. : . * **: .:: . ** :: *:** *
Rv1984c|M.tuberculosis_H37Rv QGATVIDLSTS-----------------AMPPAVADHVAAVALFGEPSSG
Mb2006c|M.bovis_AF2122/97 QGATVIDLSTS-----------------AMPPAVADHVAAVALFGEPSSG
MMAR_2934|M.marinum_M QGATVIDLAST-----------------AMPSTVADHVAAVALFGEPSSG
MAV_2741|M.avium_104 QGSTVIDLATN-----------------AMPPSVADHVAAVALFGEPSSG
TH_1243|M.thermoresistible__bu QGAALAGYVTAAAVPEEVPVEFRSYVPEPMPREVADHVAAVVLFAQPSSA
MUL_4327|M.ulcerans_Agy99 QGAAVAGYVTSASVPPGVPAAA---VPKPMAPDIADYVAAVTLFGTPSEQ
MAB_3272c|M.abscessus_ATCC_199 QGAAVVAYTTADAVPPGFELPEG--ITGPMPAEVADHVAAVALFGKPSSG
MSMEG_2474|M.smegmatis_MC2_155 QGAAVAGYTTSGAVPAGYALPAG--ITGPMPPAIAPHVAAVVLFGTPSPF
Mflv_3373|M.gilvum_PYR-GCK QGAGVIDLITLDATPRGR------FTPTPLAPHLSDRVAAVAVFGNP---
Mvan_3105|M.vanbaalenii_PYR-1 QGAGVIDLITVDPRPLGR------FTPTPMPPNVADHVAAVVVFGNP---
**: : : .:. :: ****.:*. *
Rv1984c|M.tuberculosis_H37Rv FSSMLWGGGSLPTIGPLYSSKTINLCAPDDPICT-GGGNIM---AHVSYV
Mb2006c|M.bovis_AF2122/97 FSSMLWGGGSLPTIGPLYSSKTINLCAPDDPICT-GGGNIM---AHVSYV
MMAR_2934|M.marinum_M FSSMLWGGQPLPTINPLYGAKTINLCAADDPICT-GGGNIM---AHVSYI
MAV_2741|M.avium_104 FSTMLWGGQPLPTINPLYGGKTISLCAPDDPICS-GGGNIM---AHVSYI
TH_1243|M.thermoresistible__bu LLQRYG--APPIAIGSVYQDKTLELCTEGDTICN-GVADVMPTFAHVTYT
MUL_4327|M.ulcerans_Agy99 FLQHYG--APPITIGPLYQPRTIELCASGDPVCS-GGNDAA---AHALYA
MAB_3272c|M.abscessus_ATCC_199 FLQRIDNTAPPINIGHLYVAKTMDMCVPEDPICSPDGSDNA---AHGSYG
MSMEG_2474|M.smegmatis_MC2_155 FLGLVDHSAPPLVIGPAYAAKTLQLCNTGDPVCYPGGLDRA---AHSAYK
Mflv_3373|M.gilvum_PYR-GCK -LRDLPGGGPLSQVSGVFGSRSIDLCGLDDPFCS-SGLNFP---AHFSYI
Mvan_3105|M.vanbaalenii_PYR-1 -LRDIRGGGPLPQMSGTYGSKSIDLCAFDDPFCS-PGFNLP---AHFAYV
. :. : :::.:* *..* : ** *
Rv1984c|M.tuberculosis_H37Rv QSGMTSQAATFAANRLDHAG--------------
Mb2006c|M.bovis_AF2122/97 QSGMTSQAATFAANRLDHAG--------------
MMAR_2934|M.marinum_M QAGMTDQAASFAAGKLN-----------------
MAV_2741|M.avium_104 DAGMTAHAATFAANHLNQGSPRT-----------
TH_1243|M.thermoresistible__bu WNGMPAEGAAFAADRL------------------
MUL_4327|M.ulcerans_Agy99 VNGMTGQGADFAAHHL------------------
MAB_3272c|M.abscessus_ATCC_199 DNGMTSQAADFAARQINS-----PTDTVSAAG--
MSMEG_2474|M.smegmatis_MC2_155 SNGMADQAAQFVVDHLGATSTATPAQVVSATTHP
Mflv_3373|M.gilvum_PYR-GCK KNGMVEEATNFVAGRLQ-----------------
Mvan_3105|M.vanbaalenii_PYR-1 DNGMVEEAANFAAGRLG-----------------
** ..: *.. ::