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APSSPVRLVLVDDHEMVIEGLKAMLAAFSDRVLVVGQAVGAEKAVSVVEELDPDIVLCDVRMQGVSGLDL CQTLLERNPERKVVMLSVYDDEQYLFQALRVGAAGYLLKSISSDDLVHQLEFAHSGETAIDPVMAARAAG TAARLQRDEFWPGARQGLTQRESEILSFVVAGLSNRGIANKLVIGEETVKTHLRSIYRKLGVSDRAGAVA TALREGIYQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1494 | - | - | 100% (220) | transcriptional regulatory protein DegU |
| M. smegmatis MC2 155 | MSMEG_6236 | - | 8e-32 | 36.74% (215) | two-component system, regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0856 | - | 8e-30 | 35.00% (220) | DNA-binding response regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 2e-27 | 35.24% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5014 | - | 8e-89 | 76.50% (217) | two component LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0844c | narL | 1e-27 | 35.24% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01286 | - | 7e-10 | 25.30% (166) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_1522 | - | 2e-29 | 34.91% (212) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_3480 | - | 7e-28 | 31.75% (211) | two-component transcriptional regulatory protein |
| M. avium 104 | MAV_5280 | - | 7e-28 | 32.41% (216) | two-component system response regulator |
| M. thermoresistible (build 8) | TH_3184 | - | 2e-99 | 83.64% (220) | PUTATIVE two component transcriptional regulator, LuxR family |
| M. ulcerans Agy99 | MUL_0351 | narL | 2e-28 | 35.38% (212) | nitrate/nitrite response regulator protein NarL |
| M. vanbaalenii PYR-1 | Mvan_1358 | - | 5e-97 | 80.91% (220) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1494|M.smegmatis_MC2_155 -------MAPSSPVRLVLVDDHEMVIEGLKAMLAAFSDRVLVVGQAVGAE
TH_3184|M.thermoresistible__bu ----MEPVAAPSPVRIVLVDDHEMVIEGLKAMLAAFEDRVCVVGHAVGAE
Mflv_5014|M.gilvum_PYR-GCK --------MSSEPVRIVLVDDHEMVIEGLKAMLAAFADRVCVVGQSVGAD
Mvan_1358|M.vanbaalenii_PYR-1 -------METASPVRIVLVDDHEMVIEGLKAMLAAFGSRVTVVGQAVGAD
Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGS-VNVVGEADDGA
Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGS-VNVVGEADDGA
MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGS-VNVVGEADDGA
MMAR_3480|M.marinum_M ------------MVKVFLVDDHEVVRRGLVDLLGSDPD-LEIIGEAGSVS
MAB_1522|M.abscessus_ATCC_1997 ------MTD--TEVGVLLVDDQELVRTGLRRILRRKDG-FAIVGECADGS
MAV_5280|M.avium_104 ------MTDPAPEITVLLVDDQDLVRSGLRRILRRKDG-FVIVAECADGD
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLR--DEGYDIVGEAADGQ
:.: :*. :. .: * ::... .
MSMEG_1494|M.smegmatis_MC2_155 KAVSVVEELDPDIVLCDVRMQGVSGLDLCQTLLERNPERKVVMLSVYDDE
TH_3184|M.thermoresistible__bu RAVEVVAELDPDIVLCDVRMQNTSGLDLCLTLREQAPHRKVVMLSVYDDE
Mflv_5014|M.gilvum_PYR-GCK QVMGVVTDLDPDIVLCDVRMQGSSGLDVCQQLRRRDPDRKIVMLSVYDDE
Mvan_1358|M.vanbaalenii_PYR-1 RVLGVVTELDPDIVLCDVRMQGSSGLDVCQQLRERDPDRKVVMLSVYDDE
Mb0867c|M.bovis_AF2122/97 AALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEP
Rv0844c|M.tuberculosis_H37Rv AALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEP
MUL_0351|M.ulcerans_Agy99 AALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTRVLLISAHDES
MMAR_3480|M.marinum_M EAMARIPALQPDVAVLDVRLPDGNGIELCRDLLSDLPELRCLMLTSFTSD
MAB_1522|M.abscessus_ATCC_1997 EVAAAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQ-GPPALALTTFDDD
MAV_5280|M.avium_104 EVPAAVAAHRPDVVVMDLRMRRVDGIEATRRLGGR---PPVLALTTFNED
MLBr_01286|M.leprae_Br4923 EAVELAERHKPDLVIMDVKMPRRDGIDAASEIASKR-IAPIVVLTAFSQR
. **:.: * :: .* : : : :: . .
MSMEG_1494|M.smegmatis_MC2_155 QYLFQALRVGAAGYLLKSISSDDLVHQLEFAHSGETAIDPVMAARAAGTA
TH_3184|M.thermoresistible__bu QYLYQALRVGASGYLLKSISSDELVRQLEMVHRGQTALDPGMAARAVDTA
Mflv_5014|M.gilvum_PYR-GCK QYLFQAMRVGASGYLLKSISSEDLVEQLESVHSGKTAIDPTMAARAVE--
Mvan_1358|M.vanbaalenii_PYR-1 QYLFQALRVGASGYLLKSISSEELVKQLESVHGGQTAIDPSMAARAADTA
Mb0867c|M.bovis_AF2122/97 AIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAG--
Rv0844c|M.tuberculosis_H37Rv AIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAG--
MUL_0351|M.ulcerans_Agy99 AIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAG--
MMAR_3480|M.marinum_M EAMLEAILAGASGYVVKDIKGMELARAIKDVGAGKSLLDNRAAAALMAK-
MAB_1522|M.abscessus_ATCC_1997 ELLSGALRAGAAGFILKDSPAEELVRAVHAVARGEAYLDPAVTSRVLNAY
MAV_5280|M.avium_104 ELLSGALRAGAAGFVLKDSSAEELIRAVRAVARGEGYLDPAVTSRVLTTY
MLBr_01286|M.leprae_Br4923 DLVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----------
: * ** .:::* :: : :
MSMEG_1494|M.smegmatis_MC2_155 ARLQRDEFWPGARQGLTQRESEILSFVVAGLSNRGIANKLVIGEETVKTH
TH_3184|M.thermoresistible__bu ARLQRDEFWPGARHGLTQRESEILSYVVNGLSNRGIAAKLVIGDETVKSH
Mflv_5014|M.gilvum_PYR-GCK --------WPGARQGLTQRESEILALVVNGLSNRAIAAKLIIGDETVKTH
Mvan_1358|M.vanbaalenii_PYR-1 ARMQRDEFWPGARRGLTQRESEILALVVNGLSNRAIAAKLIIGDETVKTH
Mb0867c|M.bovis_AF2122/97 ---EIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTH
Rv0844c|M.tuberculosis_H37Rv ---EIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTH
MUL_0351|M.ulcerans_Agy99 ---EIRQRAAPMAPVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTH
MMAR_3480|M.marinum_M --LRGGAEQKDPLSGLTEQERTLLGHLSEGLTNRQIAARMFLAEKTVKNY
MAB_1522|M.abscessus_ATCC_1997 R-RAPAAVSGDAQDKLTARELDVLALIASGATNSEIAEQLVISEVTVKSH
MAV_5280|M.avium_104 R-KAAPGPHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISGVTVKSH
MLBr_01286|M.leprae_Br4923 -------ALEREVATLADR-LETRKLVERAKGLLQVKQGMTEPEAFKWIQ
*: : : . : :
MSMEG_1494|M.smegmatis_MC2_155 LRSIYRKLGVSDRAGAVATALREGIYQ------
TH_3184|M.thermoresistible__bu LRSIYRKLGVSDRAAAVATALREGIYQ------
Mflv_5014|M.gilvum_PYR-GCK LSSIYRKLGVSDRTAAVATALREGIFQ------
Mvan_1358|M.vanbaalenii_PYR-1 LSSIYRKLGVSDRTAAAATALREGIYQ------
Mb0867c|M.bovis_AF2122/97 VQRLYEKLGVSDRAAAVAEAMRQRLLD------
Rv0844c|M.tuberculosis_H37Rv VQRLYEKLGVSDRAAAVAEAMRQRLLD------
MUL_0351|M.ulcerans_Agy99 VQRLYEKLGVSDRAAAVAEAMRQGLLD------
MMAR_3480|M.marinum_M VSRLLAKLGMERRTQAAVFASRLGQGTRPVQGD
MAB_1522|M.abscessus_ATCC_1997 IGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
MAV_5280|M.avium_104 IGRIFGKLDLRDRAAAIVYAYDNGIVAPR----
MLBr_01286|M.leprae_Br4923 RAAMDRRTTMKRVAEVVLETLDTPKDT------
: : : : . :