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M. thermoresistible (build 8) TH_1508 ()

annotation: Possible transcriptional regulatory protein
coordinates: 2845100 - 2845648
length: 183

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1508-100% (183)Possible transcriptional regulatory protein
M. thermoresistible (build 8)TH_4110-4e-1030.34% (145) PUTATIVE putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_2255-7e-0830.00% (120) TetR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2274c-2e-5258.76% (177) transcriptional regulator
M. gilvum PYR-GCKMflv_2773-8e-5961.54% (182) TetR family transcriptional regulator
M. tuberculosis H37RvRv2250c-8e-5258.19% (177) transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3883c-3e-3845.86% (181) TetR family transcriptional regulator
M. marinum MMMAR_3343-2e-5055.00% (180) transcriptional regulatory protein
M. avium 104MAV_2187-9e-5258.99% (178) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_4333-4e-5964.44% (180) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_1299-3e-5055.00% (180) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_3760-1e-5963.19% (182) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb2274c|M.bovis_AF2122/97           MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAEI
Rv2250c|M.tuberculosis_H37Rv        MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAEI
MMAR_3343|M.marinum_M               MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAEI
MUL_1299|M.ulcerans_Agy99           MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAEI
MAV_2187|M.avium_104                MLSIRNDRP----------DAALDTGERILAAAASCVVDFGVDRVTLAEI
MSMEG_4333|M.smegmatis_MC2_155      MVSISNDDA----------G--ESLGERILEAAASCVMAFGVDRVTLAEI
TH_1508|M.thermoresistible__bu      ------------------------VEDRILDAAAASVLAVGVNRVTLTDI
Mflv_2773|M.gilvum_PYR-GCK          MMSIRNSE---------------PVEQRILDAAAECIRAYGVERTTVTEI
Mvan_3760|M.vanbaalenii_PYR-1       MVSIRNPER--------------SVEQRILDAAAACILAYGVERTTMTEI
MAB_3883c|M.abscessus_ATCC_199      MAPLVDAGGGVTVQAMDAQASADPVTERILDAALSCVTEFGVRRTTLVEV
                                                               *** **  .:   ** *.*:.::

Mb2274c|M.bovis_AF2122/97           ARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDDREALVKQ
Rv2250c|M.tuberculosis_H37Rv        ARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQ
MMAR_3343|M.marinum_M               ARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVRAVSLDGHDRQTVVRQ
MUL_1299|M.ulcerans_Agy99           ARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVRAVFLDGHDRQTVVRQ
MAV_2187|M.avium_104                ARRAGVSRPTVYRRWPDTRSIVAALLTRHVTDVMRAAPLLGDDRESLVRQ
MSMEG_4333|M.smegmatis_MC2_155      ARRAGVSRPTVYRRFPDTRSILAALLTARIVRVLDEVESDARGREALVRR
TH_1508|M.thermoresistible__bu      ARRARVSRPTIYRRWPDTNALLASLLTTRITAVLDEVPTRGNDRESLVER
Mflv_2773|M.gilvum_PYR-GCK          ARRAGVSRPTIYRRWPDIRWVIAEVLTVRISDVLAAVPAAGPGREELVDR
Mvan_3760|M.vanbaalenii_PYR-1       ARRARVSRPTIYRRWPDIRWVIAELLTVRITGVLEAVPDRGAGRESVVGR
MAB_3883c|M.abscessus_ATCC_199      AKRAGVSRPSVYRRWPDVRTLVAELLTREMGSILPATG-RGCARERLVRS
                                    *:** ****::***:** . ::: :** .:  ::  .   .  *: :*  

Mb2274c|M.bovis_AF2122/97           IVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARLTV
Rv2250c|M.tuberculosis_H37Rv        IVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARLTV
MMAR_3343|M.marinum_M               VVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLAARLQV
MUL_1299|M.ulcerans_Agy99           VVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLAARLQV
MAV_2187|M.avium_104                IVTVADLLRQDRLVMSVLHS--ELAPIYITERLGTSQHMLIDALAARLRV
MSMEG_4333|M.smegmatis_MC2_155      IVAVAERLRHDEVIMAVLHTAPDVAMVYIAERLGTSQQILIDAVAGEIKI
TH_1508|M.thermoresistible__bu      IVGFAERLRADEVVMSVLYGAPEFTMVYITDRLGSSQRIMIEALAREIAE
Mflv_2773|M.gilvum_PYR-GCK          VVRIAEHLRRDDIVMSVIFNAPTLAMVYITERLGTSQQLLIDTLAAAIVQ
Mvan_3760|M.vanbaalenii_PYR-1       VVAVADHLRADEIVQSVIRNAPGLAMTYITDRLGTSQQILIDALAEAIKA
MAB_3883c|M.abscessus_ATCC_199      VTGLVTQVREHSIFAAILRSDPELLLTYIVQRLGTSQRALIGWTAMLIVE
                                    :. ..  :* . :. :::     .   **.:***:**: ::   *  :  

Mb2274c|M.bovis_AF2122/97           AQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHAL
Rv2250c|M.tuberculosis_H37Rv        AQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHAL
MMAR_3343|M.marinum_M               AQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAELTYSL
MUL_1299|M.ulcerans_Agy99           AQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAELTYSL
MAV_2187|M.avium_104                AQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEALATELAYSL
MSMEG_4333|M.smegmatis_MC2_155      AQEGGSVRAGDARQLATMCLLITQSAIQSAQMVAPILDADALARELAYSL
TH_1508|M.thermoresistible__bu      AQETGTVRAGDPHQLAAMCGLIAQSAVQSARIVEPFLDSEALAAELRRSL
Mflv_2773|M.gilvum_PYR-GCK          GQAHGSVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNAELAHSL
Mvan_3760|M.vanbaalenii_PYR-1       GQDEGSIRAGDPRGMAAMCLLITQSTIQSAQMVAELLDNEALNEELAHSL
MAB_3883c|M.abscessus_ATCC_199      GQADGSIRAGIPEQMAAMVLLIGQSVLQSARIVADILSPDELVDELATAI
                                    .*  *::*.* .  :.:*  ** **.:**. ::  :*.   *  **  ::

Mb2274c|M.bovis_AF2122/97           NGYLC-
Rv2250c|M.tuberculosis_H37Rv        NGYLC-
MMAR_3343|M.marinum_M               NGYLA-
MUL_1299|M.ulcerans_Agy99           NGYLA-
MAV_2187|M.avium_104                NGYLS-
MSMEG_4333|M.smegmatis_MC2_155      NGYLKP
TH_1508|M.thermoresistible__bu      NGYLKP
Mflv_2773|M.gilvum_PYR-GCK          NGYLKP
Mvan_3760|M.vanbaalenii_PYR-1       NGYLKP
MAB_3883c|M.abscessus_ATCC_199      DGYLKA
                                    :***