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TKSWPSRRSTPTVRKGDLREQQILDAAEDLLTTTGYADMTVADIAESVGITRAALYFYFGSKQEVLTALV ARTVQVLRDRAAGAARDQTRPVDEAIGAALERTAELWRDHGPVMRMAVDLASTVPAIDELWSEAAEVSID AMADVLRRAGVPTGTAPGDAPGLARALCWMIERTFYQASKISPDAIADAKLTCETVWRQVAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3425 | - | - | 100% (204) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4022 | - | 7e-56 | 54.08% (196) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1967 | - | 7e-37 | 47.47% (198) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 2e-13 | 31.63% (215) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_0963 | - | 2e-15 | 34.39% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 2e-13 | 31.63% (215) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_01070 | - | 7e-14 | 33.51% (188) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4089c | - | 2e-13 | 32.12% (193) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5405 | ethR | 2e-12 | 33.33% (177) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1977 | - | 4e-56 | 53.57% (196) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_1150 | - | 1e-16 | 33.84% (198) | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR |
| M. ulcerans Agy99 | MUL_5027 | ethR | 6e-12 | 33.73% (166) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5684 | - | 4e-12 | 31.76% (170) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3425|M.smegmatis_MC2_155 -MTKSWPS--------------RRSTPTVRKGDLREQQILDAAEDLLTTT
MAV_1977|M.avium_104 -MT-------------------RRRAGEPRKGDLREAAILDAAEELLGAI
Mb3885|M.bovis_AF2122/97 -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
Rv3855|M.tuberculosis_H37Rv -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
MMAR_5405|M.marinum_M MVSTSTASQAS---------PSRGRRSARPSGDERELAILNTAEKLLEDR
MUL_5027|M.ulcerans_Agy99 -MSTSTASQAS---------LSRGRRSARPSGDERELAILNTAEKLLEDR
Mvan_5684|M.vanbaalenii_PYR-1 -MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLADR
Mflv_0963|M.gilvum_PYR-GCK -MSSTTRTG-------------RGRRAARPSGDDRESAILTTAEQLLEQR
TH_1150|M.thermoresistible__bu -MSTASPVRS------------RGRRSTRPSGDDRELAILTTAEKLLAER
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSN------YVPASRGRRSSQLSGDDREQAILAVAERLLAER
MAB_4089c|M.abscessus_ATCC_199 -MSGR-----------------PRRISPIREGNSTRDEILDASAELFTTD
: .*: . ** .: *:
MSMEG_3425|M.smegmatis_MC2_155 GYADMTVADIAESVGITRAALYFYFGSKQEVLTALVARTVQVLRDRAAGA
MAV_1977|M.avium_104 GYDAMTIADIAARAGITRGALYFYFGSKQEVITALFARTVAVLHEKSR-A
Mb3885|M.bovis_AF2122/97 PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MMAR_5405|M.marinum_M PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
MUL_5027|M.ulcerans_Agy99 PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
Mvan_5684|M.vanbaalenii_PYR-1 SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
Mflv_0963|M.gilvum_PYR-GCK PLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRVIAEANARADAA
TH_1150|M.thermoresistible__bu PLAEISVDDLAKGAGLSRPTFYFYFPSKDAVLLALVERVIAEADQRADAA
MLBr_01070|M.leprae_Br4923 PLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEAL
MAB_4089c|M.abscessus_ATCC_199 GFAATTTRRIAESVGIQQASLYYHFKTKDDILDALLAMTIDQPLHYAALI
: :* .*: : ::*::* :*: :: :*.
MSMEG_3425|M.smegmatis_MC2_155 ARDQT---RPVDEAIGAALERTAELWR---DHGPVMRMAVDLASTVPAID
MAV_1977|M.avium_104 ATEDA---ASGAKAIDTAMRRTEDLWR---EHGVVMRTAIDLAATVPQLD
Mb3885|M.bovis_AF2122/97 AENPA--DTDRENMWRTGINVFFETFG---SHKAVTRAGQAARATSVEVA
Rv3855|M.tuberculosis_H37Rv AENPA--DTDRENMWRTGINVFFETFG---SHKAVTRAGQAARATSVEVA
MMAR_5405|M.marinum_M AQAP---DVDHVTMWRNGINVFFETFG---SHRAVVQGGQGVRSISAEVR
MUL_5027|M.ulcerans_Agy99 AQAP---DVDHVTMWRNGINVFFETFG---SHRAVVQGGQGVRSISTEVR
Mvan_5684|M.vanbaalenii_PYR-1 IAER---SSDRRTIWRRGINVFFETFG---AHRAVCATTVGVKSTNSEAR
Mflv_0963|M.gilvum_PYR-GCK LGGRDDRPLEPAGVWQ-AIKALFETFA---AHRAVMLAGAAMRPNNPEVQ
TH_1150|M.thermoresistible__bu LNGMDARAVDPAGVWR-AINALFETFG---AHRAVTLAGAAARTTNTEVD
MLBr_01070|M.leprae_Br4923 AEQLP---ADPAAVWRSAITAFFEVCG---THRAVAVAGAAAKATSPEVR
MAB_4089c|M.abscessus_ATCC_199 ADRPE---APVVRLYALALGDAAQLAASRWNLGALYLLPDLRAERFSAFR
.: : :
MSMEG_3425|M.smegmatis_MC2_155 ELWSEAAEVSIDAMADVLRRAGVPTGTAPG--DAPGLARALCWMIERTFY
MAV_1977|M.avium_104 ALWKQTADIFVVAITAILEHMGVPAGKGPD--KSAAIAEALCWMIERNFY
Mb3885|M.bovis_AF2122/97 ELWSTFMQKWIAYTAAVIDAE-RDRGAAPRTLPAHELATALNLMNERTLF
Rv3855|M.tuberculosis_H37Rv ELWSTFMQKWIAYTAAVIDAE-RDRGAAPRTLPAHELATALNLMNERTLF
MMAR_5405|M.marinum_M ELWSTFMQKWIAYTAKIIEAE-RERGAAPVTLPALELATALNLMNERTLS
MUL_5027|M.ulcerans_Agy99 ELWSTFMQKWIAYTAKIIEAE-RERGAAPVTLPALELATALNLMNERTLS
Mvan_5684|M.vanbaalenii_PYR-1 ELWSRSMQRWIDHIAAVIEAE-RADGAAPVTVPARELSTALNLMNESVMT
Mflv_0963|M.gilvum_PYR-GCK RVWSHFMQKWIDYTAASIRAE-RERGAAPDTLPAEDLAIALNLMNERIML
TH_1150|M.thermoresistible__bu ALWSRFMKKWIDYTAESIRAE-RERGAAPDTIPAEDLAVSLNLMNERTMF
MLBr_01070|M.leprae_Br4923 RLWSTVMQQWIDYNTAAIQAE-RKCGVAPDTIPAEDLAVALQLMTERVMA
MAB_4089c|M.abscessus_ATCC_199 RKRDQLRTHYQELAAAACRASMLRAGVERLPFRLVESVIMLRADGDSIAP
. : * * :
MSMEG_3425|M.smegmatis_MC2_155 QASKISPDAIA----DAKLTCETVWRQVAVR---------
MAV_1977|M.avium_104 QASRVSPARLT----RARQTCTEIWLRVAS----------
Mb3885|M.bovis_AF2122/97 ASFAGEQPSVP----EARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv ASFAGEQPSVP----EARVLDTLVHIWVTSIYGENR----
MMAR_5405|M.marinum_M ASFLAEEPSVP----ETHVVDTLVHIWVSSIYGEAR----
MUL_5027|M.ulcerans_Agy99 ASFLAEEPSVP----ETHVVDTLVHVWVSSIYGAAR----
Mvan_5684|M.vanbaalenii_PYR-1 ATFTGHQPAIP----DDRVLDNLVHIWTTSIYGKTD----
Mflv_0963|M.gilvum_PYR-GCK SAFASEQAAVT----ADRLVGTLAHIWVSSIYGTPRA---
TH_1150|M.thermoresistible__bu AAFADEKPAVP----EDRIVDTLAHIWLTSIYGTGR----
MLBr_01070|M.leprae_Br4923 ATFSDEKPLIP----DKKVIDTLVHIWLASIYGS------
MAB_4089c|M.abscessus_ATCC_199 EALADATLRVVGVTGDAGEIEGAARVLLGQLGWPVAIPKR
: :