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VSIRNPERSVEQRILDAAAACILAYGVERTTMTEIARRARVSRPTIYRRWPDIRWVIAELLTVRITGVLE AVPDRGAGRESVVGRVVAVADHLRADEIVQSVIRNAPGLAMTYITDRLGTSQQILIDALAEAIKAGQDEG SIRAGDPRGMAAMCLLITQSTIQSAQMVAELLDNEALNEELAHSLNGYLKP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3760 | - | - | 100% (192) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 1e-07 | 29.66% (145) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4342 | - | 5e-07 | 41.43% (70) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 8e-52 | 54.21% (190) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2773 | - | 1e-75 | 76.04% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 1e-51 | 54.21% (190) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3883c | - | 2e-44 | 50.28% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3343 | - | 3e-52 | 54.74% (190) | transcriptional regulatory protein |
| M. avium 104 | MAV_2187 | - | 4e-53 | 57.73% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4333 | - | 2e-61 | 61.34% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1508 | - | 8e-60 | 63.19% (182) | Possible transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_1299 | - | 4e-52 | 54.74% (190) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3760|M.vanbaalenii_PYR-1 MVSIRNPER--------------SVEQRILDAAAACILAYGVERTTMTEI
Mflv_2773|M.gilvum_PYR-GCK MMSIRNSE---------------PVEQRILDAAAECIRAYGVERTTVTEI
Mb2274c|M.bovis_AF2122/97 MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAEI
Rv2250c|M.tuberculosis_H37Rv MLSMSNDR--------------ADTGGRILRAAASCVVDYGVDRVTLAEI
MMAR_3343|M.marinum_M MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAEI
MUL_1299|M.ulcerans_Agy99 MLSMSNAP--------------EDIGDRILQAAASCVRDYGVDRVTLAEI
MAV_2187|M.avium_104 MLSIRNDRP----------DAALDTGERILAAAASCVVDFGVDRVTLAEI
MSMEG_4333|M.smegmatis_MC2_155 MVSISNDDA----------G--ESLGERILEAAASCVMAFGVDRVTLAEI
TH_1508|M.thermoresistible__bu ------------------------VEDRILDAAAASVLAVGVNRVTLTDI
MAB_3883c|M.abscessus_ATCC_199 MAPLVDAGGGVTVQAMDAQASADPVTERILDAALSCVTEFGVRRTTLVEV
*** ** .: ** *.*:.::
Mvan_3760|M.vanbaalenii_PYR-1 ARRARVSRPTIYRRWPDIRWVIAELLTVRITGVLEAVPDRGAGRESVVGR
Mflv_2773|M.gilvum_PYR-GCK ARRAGVSRPTIYRRWPDIRWVIAEVLTVRISDVLAAVPAAGPGREELVDR
Mb2274c|M.bovis_AF2122/97 ARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREVPLDGDDREALVKQ
Rv2250c|M.tuberculosis_H37Rv ARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQ
MMAR_3343|M.marinum_M ARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVRAVSLDGHDRQTVVRQ
MUL_1299|M.ulcerans_Agy99 ARRAGVSRPTVYRRWPDTRSIISALLTSHVTDVVRAVFLDGHDRQTVVRQ
MAV_2187|M.avium_104 ARRAGVSRPTVYRRWPDTRSIVAALLTRHVTDVMRAAPLLGDDRESLVRQ
MSMEG_4333|M.smegmatis_MC2_155 ARRAGVSRPTVYRRFPDTRSILAALLTARIVRVLDEVESDARGREALVRR
TH_1508|M.thermoresistible__bu ARRARVSRPTIYRRWPDTNALLASLLTTRITAVLDEVPTRGNDRESLVER
MAB_3883c|M.abscessus_ATCC_199 AKRAGVSRPSVYRRWPDVRTLVAELLTREMGSILPATG-RGCARERLVRS
*:** ****::***:** . ::: :** .: :: . . *: :*
Mvan_3760|M.vanbaalenii_PYR-1 VVAVADHLRADEIVQSVIRNAPGLAMTYITDRLGTSQQILIDALAEAIKA
Mflv_2773|M.gilvum_PYR-GCK VVRIAEHLRRDDIVMSVIFNAPTLAMVYITERLGTSQQLLIDTLAAAIVQ
Mb2274c|M.bovis_AF2122/97 IVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARLTV
Rv2250c|M.tuberculosis_H37Rv IVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARLTV
MMAR_3343|M.marinum_M VVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLAARLQV
MUL_1299|M.ulcerans_Agy99 VVAVADRLRGDELVKALMHS--DLARVYITERLGASQHFLLEGLAARLQV
MAV_2187|M.avium_104 IVTVADLLRQDRLVMSVLHS--ELAPIYITERLGTSQHMLIDALAARLRV
MSMEG_4333|M.smegmatis_MC2_155 IVAVAERLRHDEVIMAVLHTAPDVAMVYIAERLGTSQQILIDAVAGEIKI
TH_1508|M.thermoresistible__bu IVGFAERLRADEVVMSVLYGAPEFTMVYITDRLGSSQRIMIEALAREIAE
MAB_3883c|M.abscessus_ATCC_199 VTGLVTQVREHSIFAAILRSDPELLLTYIVQRLGTSQRALIGWTAMLIVE
:. .. :* . :. ::: . **.:***:**: :: * :
Mvan_3760|M.vanbaalenii_PYR-1 GQDEGSIRAGDPRGMAAMCLLITQSTIQSAQMVAELLDNEALNEELAHSL
Mflv_2773|M.gilvum_PYR-GCK GQAHGSVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNAELAHSL
Mb2274c|M.bovis_AF2122/97 AQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHAL
Rv2250c|M.tuberculosis_H37Rv AQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHAL
MMAR_3343|M.marinum_M AQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAELTYSL
MUL_1299|M.ulcerans_Agy99 AQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAELTYSL
MAV_2187|M.avium_104 AQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEALATELAYSL
MSMEG_4333|M.smegmatis_MC2_155 AQEGGSVRAGDARQLATMCLLITQSAIQSAQMVAPILDADALARELAYSL
TH_1508|M.thermoresistible__bu AQETGTVRAGDPHQLAAMCGLIAQSAVQSARIVEPFLDSEALAAELRRSL
MAB_3883c|M.abscessus_ATCC_199 GQADGSIRAGIPEQMAAMVLLIGQSVLQSARIVADILSPDELVDELATAI
.* *::*.* . :.:* ** **.:**. :: :*. * ** ::
Mvan_3760|M.vanbaalenii_PYR-1 NGYLKP
Mflv_2773|M.gilvum_PYR-GCK NGYLKP
Mb2274c|M.bovis_AF2122/97 NGYLC-
Rv2250c|M.tuberculosis_H37Rv NGYLC-
MMAR_3343|M.marinum_M NGYLA-
MUL_1299|M.ulcerans_Agy99 NGYLA-
MAV_2187|M.avium_104 NGYLS-
MSMEG_4333|M.smegmatis_MC2_155 NGYLKP
TH_1508|M.thermoresistible__bu NGYLKP
MAB_3883c|M.abscessus_ATCC_199 DGYLKA
:***