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MMSIRNSEPVEQRILDAAAECIRAYGVERTTVTEIARRAGVSRPTIYRRWPDIRWVIAEVLTVRISDVLA AVPAAGPGREELVDRVVRIAEHLRRDDIVMSVIFNAPTLAMVYITERLGTSQQLLIDTLAAAIVQGQAHG SVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNAELAHSLNGYLKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2773 | - | - | 100% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3024 | - | 7e-09 | 36.13% (119) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0492 | - | 1e-08 | 40.86% (93) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 2e-51 | 58.76% (177) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv2250c | - | 2e-52 | 59.32% (177) | transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 7e-06 | 30.00% (120) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3883c | - | 1e-45 | 49.73% (187) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3343 | - | 1e-50 | 53.68% (190) | transcriptional regulatory protein |
| M. avium 104 | MAV_2187 | - | 2e-55 | 58.25% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4333 | - | 3e-58 | 59.79% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1508 | - | 7e-59 | 61.54% (182) | Possible transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_1299 | - | 2e-50 | 53.68% (190) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3760 | - | 2e-75 | 76.04% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2773|M.gilvum_PYR-GCK -----------------------------------MMSIRNSE-------
Mvan_3760|M.vanbaalenii_PYR-1 -----------------------------------MVSIRNPER------
Mb2274c|M.bovis_AF2122/97 -----------------------------------MLSMSNDR-------
Rv2250c|M.tuberculosis_H37Rv -----------------------------------MLSMSNDR-------
MMAR_3343|M.marinum_M -----------------------------------MLSMSNAP-------
MUL_1299|M.ulcerans_Agy99 -----------------------------------MLSMSNAP-------
MAV_2187|M.avium_104 -----------------------------------MLSIRNDRP------
MSMEG_4333|M.smegmatis_MC2_155 -----------------------------------MVSISNDDA------
TH_1508|M.thermoresistible__bu --------------------------------------------------
MAB_3883c|M.abscessus_ATCC_199 -----------------------------------MAPLVDAGGGVTVQA
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mflv_2773|M.gilvum_PYR-GCK --------PVEQRILDAAAECIRAYGVERTTVTEIARRAGVSRPTIYRRW
Mvan_3760|M.vanbaalenii_PYR-1 --------SVEQRILDAAAACILAYGVERTTMTEIARRARVSRPTIYRRW
Mb2274c|M.bovis_AF2122/97 -------ADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRW
Rv2250c|M.tuberculosis_H37Rv -------ADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRW
MMAR_3343|M.marinum_M -------EDIGDRILQAAASCVRDYGVDRVTLAEIARRAGVSRPTVYRRW
MUL_1299|M.ulcerans_Agy99 -------EDIGDRILQAAASCVRDYGVDRVTLAEIARRAGVSRPTVYRRW
MAV_2187|M.avium_104 ----DAALDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRW
MSMEG_4333|M.smegmatis_MC2_155 ----G--ESLGERILEAAASCVMAFGVDRVTLAEIARRAGVSRPTVYRRF
TH_1508|M.thermoresistible__bu ---------VEDRILDAAAASVLAVGVNRVTLTDIARRARVSRPTIYRRW
MAB_3883c|M.abscessus_ATCC_199 MDAQASADPVTERILDAALSCVTEFGVRRTTLVEVAKRAGVSRPSVYRRW
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLGP-EVSVREIAEEAGTAKPKIYRHF
.*: ** .: * ..:: ::*..* .::*.:**::
Mflv_2773|M.gilvum_PYR-GCK PDIRWVIAEVLTVR----ISDVLAAVPAAGPGREELVDR----VVRIAEH
Mvan_3760|M.vanbaalenii_PYR-1 PDIRWVIAELLTVR----ITGVLEAVPDRGAGRESVVGR----VVAVADH
Mb2274c|M.bovis_AF2122/97 PDTRSIMASMLTSH----IAAVLREVPLDGDDREALVKQ----IVAVADR
Rv2250c|M.tuberculosis_H37Rv PDTRSIMASMLTSH----IADVLREVPLDGDDREALVKQ----IVAVADR
MMAR_3343|M.marinum_M PDTRSIISALLTSH----VTDVVRAVSLDGHDRQTVVRQ----VVAVADR
MUL_1299|M.ulcerans_Agy99 PDTRSIISALLTSH----VTDVVRAVFLDGHDRQTVVRQ----VVAVADR
MAV_2187|M.avium_104 PDTRSIVAALLTRH----VTDVMRAAPLLGDDRESLVRQ----IVTVADL
MSMEG_4333|M.smegmatis_MC2_155 PDTRSILAALLTAR----IVRVLDEVESDARGREALVRR----IVAVAER
TH_1508|M.thermoresistible__bu PDTNALLASLLTTR----ITAVLDEVPTRGNDRESLVER----IVGFAER
MAB_3883c|M.abscessus_ATCC_199 PDVRTLVAELLTRE----MGSILPATG-RGCARERLVRS----VTGLVTQ
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDK
.* :. : :. . :: . ..
Mflv_2773|M.gilvum_PYR-GCK LR-------------RDDIVMSVIFNAPTLAMVYITERLGTSQQLLIDTL
Mvan_3760|M.vanbaalenii_PYR-1 LR-------------ADEIVQSVIRNAPGLAMTYITDRLGTSQQILIDAL
Mb2274c|M.bovis_AF2122/97 LR-------------GDDLIMSVMHS--ELARVYITERLGTSQQVLIEGL
Rv2250c|M.tuberculosis_H37Rv LR-------------GDDLIMSVMHS--ELARVYITERLGTSQQVLIEGL
MMAR_3343|M.marinum_M LR-------------GDELVKALMHS--DLARVYITERLGASQHFLLEGL
MUL_1299|M.ulcerans_Agy99 LR-------------GDELVKALMHS--DLARVYITERLGASQHFLLEGL
MAV_2187|M.avium_104 LR-------------QDRLVMSVLHS--ELAPIYITERLGTSQHMLIDAL
MSMEG_4333|M.smegmatis_MC2_155 LR-------------HDEVIMAVLHTAPDVAMVYIAERLGTSQQILIDAV
TH_1508|M.thermoresistible__bu LR-------------ADEVVMSVLYGAPEFTMVYITDRLGSSQRIMIEAL
MAB_3883c|M.abscessus_ATCC_199 VR-------------EHSIFAAILRSDPELLLTYIVQRLGTSQRALIGWT
MLBr_01733|M.leprae_Br4923 HPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRA
: . . :. :
Mflv_2773|M.gilvum_PYR-GCK AAAIVQGQAHGSVRAG---------DPHQMGAMCLLIAQSTIQSAQMVEK
Mvan_3760|M.vanbaalenii_PYR-1 AEAIKAGQDEGSIRAG---------DPRGMAAMCLLITQSTIQSAQMVAE
Mb2274c|M.bovis_AF2122/97 AARLTVAQRSGSVRSG---------DARRLATMVLLIAQSTIQSADIVDS
Rv2250c|M.tuberculosis_H37Rv AARLTVAQRSGSVRSG---------DARRLATMVLLIAQSTIQSADIVDS
MMAR_3343|M.marinum_M AARLQVAQGTGSVRAG---------DPRKLAAMVLLITQSTIQSVDIIDP
MUL_1299|M.ulcerans_Agy99 AARLQVAQGTGSVRAG---------DPRKLAAMVLLITQSTIQSVDIIDP
MAV_2187|M.avium_104 AARLRVAQRNGSVRPG---------DPVQMATMVLLIAQSTIQSAQIVEP
MSMEG_4333|M.smegmatis_MC2_155 AGEIKIAQEGGSVRAG---------DARQLATMCLLITQSAIQSAQMVAP
TH_1508|M.thermoresistible__bu AREIAEAQETGTVRAG---------DPHQLAAMCGLIAQSAVQSARIVEP
MAB_3883c|M.abscessus_ATCC_199 AMLIVEGQADGSIRAG---------IPEQMAAMVLLIGQSVLQSARIVAD
MLBr_01733|M.leprae_Br4923 ASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVG
* : *:: .. . . :: : .: ::
Mflv_2773|M.gilvum_PYR-GCK FLDRDALNAELAHSLNGYLKP-----
Mvan_3760|M.vanbaalenii_PYR-1 LLDNEALNEELAHSLNGYLKP-----
Mb2274c|M.bovis_AF2122/97 ILDSAALATELTHALNGYLC------
Rv2250c|M.tuberculosis_H37Rv ILDSAALATELTHALNGYLC------
MMAR_3343|M.marinum_M ILDSEALAAELTYSLNGYLA------
MUL_1299|M.ulcerans_Agy99 ILDSEALAAELTYSLNGYLA------
MAV_2187|M.avium_104 LLDAEALATELAYSLNGYLS------
MSMEG_4333|M.smegmatis_MC2_155 ILDADALARELAYSLNGYLKP-----
TH_1508|M.thermoresistible__bu FLDSEALAAELRRSLNGYLKP-----
MAB_3883c|M.abscessus_ATCC_199 ILSPDELVDELATAIDGYLKA-----
MLBr_01733|M.leprae_Br4923 TAETLGISMNPDRPIHDAVPLDRSAS
. : : .:.. :