For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDKVAVLTGADGGLGRAVAQRLAKDGFTLVLGYHPGSEAPQTPEALTVPADVTSEHDVAKLTSAAVIEYG RIDALVTLAGVMEQTLLPDLDLATWNQTIAVNLTGTFLCAKAAADELMKTGGTIVTIGSQIGYVGGINCA AYTASKAGVAGLTRALARELGPTVRVNCVAPGPIETPMTAVHATPEWVEQKTRSLVMGRFGTPDEVATAV SWLVGDEASFVTGQTINVNGGGAMP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4169 | - | - | 100% (236) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_3009 | - | 7e-34 | 38.56% (236) | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 1e-33 | 38.84% (242) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 7e-35 | 35.95% (242) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4505 | - | 9e-35 | 36.82% (239) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 8e-35 | 35.95% (242) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-30 | 35.06% (231) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 5e-33 | 38.53% (231) | 3-oxoacyl- |
| M. marinum M | MMAR_4927 | - | 1e-32 | 33.88% (242) | dehydrogenase/reductase |
| M. avium 104 | MAV_2509 | - | 9e-35 | 37.66% (239) | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase |
| M. thermoresistible (build 8) | TH_2623 | - | 1e-35 | 38.27% (243) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0478 | - | 1e-31 | 33.47% (242) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 7e-34 | 37.14% (245) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2882c|M.bovis_AF2122/97 -MMDLSQRLAGRVAVITGG------GSGIGLAAGRRMRAEGATIVVGDVD
Rv2857c|M.tuberculosis_H37Rv -MMDLSQRLAGRVAVITGG------GSGIGLAAGRRMRAEGATIVVGDVD
MMAR_4927|M.marinum_M MG-----QFENKVAIVTGA------AQGIGQAYADALAREGARVVVADIN
MUL_0478|M.ulcerans_Agy99 MG-----QFENKVAIVTGA------AQGIGQAYADALAREGARVVVADIN
TH_2623|M.thermoresistible__bu MGVLDKFRLDDKVVIVTGA------SSGLGVAFARACAEAGADVVLAARR
MSMEG_4169|M.smegmatis_MC2_155 --------MTDKVAVLTGA------DGGLGRAVAQRLAKDGFTLVLGYHP
Mflv_4505|M.gilvum_PYR-GCK ----MTGRLAGKVALISGA------ARGMGASHARVMAGHGAKVVCGDIL
MAV_2509|M.avium_104 ----MAERLAGKVALVSGG------ARGMGASHVRSLVAEGAKVVFGDIL
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
MAB_2723c|M.abscessus_ATCC_199 ---------MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRL
Mvan_4185|M.vanbaalenii_PYR-1 ---------MTRVAVVTGG------ASGMGEATCHELGRRGCKVAVLDLD
. : : * :.
Mb2882c|M.bovis_AF2122/97 VEAGGAAADELS-------GLFVPTDVCDEDAVNGLFDGAAETYGRIDIA
Rv2857c|M.tuberculosis_H37Rv VEAGGAAADELS-------GLFVPTDVCDEDAVNGLFDGAAETYGRIDIA
MMAR_4927|M.marinum_M AEAAEKTAKQIVAD--GGTAIHVPVDVSDEESARAMADRTVSEFGGIDYL
MUL_0478|M.ulcerans_Agy99 AEAAEKTAKQIVAD--GGTAIHVPVDVSDEESARAMADRTVSEFGGIDYL
TH_2623|M.thermoresistible__bu VERLQQTAEQVRAT--GRRALTVATDVVDPQQCQEMVDAAMTEFGRVDVL
MSMEG_4169|M.smegmatis_MC2_155 GSEAPQTP----------EALTVPADVTSEHDVAKLTSAAVIEYGRIDAL
Mflv_4505|M.gilvum_PYR-GCK DSDGEAVAAELG-----DAARYVHLDVTSPDDWDRAVAAAVADFGGLDVL
MAV_2509|M.avium_104 DDEGKAVAAEVG-----EATRYLHLDVTKPEDWDAAVATALAEFGRIDVL
MLBr_01807|M.leprae_Br4923 VADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVL
MAB_2723c|M.abscessus_ATCC_199 AADGHKVAVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVL
Mvan_4185|M.vanbaalenii_PYR-1 GQAAQRVAEELRGDGVPA--LGVAADVTDRAAVEDAFAKVRTELGPVHIL
.. : *: . . * :.
Mb2882c|M.bovis_AF2122/97 FNNAGIS-PPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGK
Rv2857c|M.tuberculosis_H37Rv FNNAGIS-PPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLAGK
MMAR_4927|M.marinum_M VNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKRGG
MUL_0478|M.ulcerans_Agy99 VNNAAIYGGMKLDLQLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKRGG
TH_2623|M.thermoresistible__bu VNNAGV--GTAVPATRETP-EEFRTVIDINLNGSYWAAQACGRVMRP--G
MSMEG_4169|M.smegmatis_MC2_155 VTLAGV---MEQTLLPDLDLATWNQTIAVNLTGTFLCAKAAADELMKT-G
Mflv_4505|M.gilvum_PYR-GCK VNNAGI---LNIGTVEDYELSEWHRILDVNLTGVFLGIRAATPTMKAAGR
MAV_2509|M.avium_104 VNNAGI---INIGTLEDYALSEWQRILDINLTGVFLGIRAVVKPMKKAGR
MLBr_01807|M.leprae_Br4923 VANAGIT---SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
MAB_2723c|M.abscessus_ATCC_199 VANAGIT---ADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRF
Mvan_4185|M.vanbaalenii_PYR-1 VTSAGLV---DFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGW
. *.: : * . : :
Mb2882c|M.bovis_AF2122/97 GSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQG-IRVNA
Rv2857c|M.tuberculosis_H37Rv GSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQG-IRVNA
MMAR_4927|M.marinum_M GAIVNQSS----TAAWLYSNFYGLAKVGVNGLTQQLSRELGGMK-IRINA
MUL_0478|M.ulcerans_Agy99 GAIVNQSS----TAAWLYSNFYGLAKVGVNGLTQQLSRELGGMK-IRINA
TH_2623|M.thermoresistible__bu SSIVNISSILGITTASLPQAAYSASKAGVIGLTRDLAQQWTPRKGIRVNA
MSMEG_4169|M.smegmatis_MC2_155 GTIVTIGSQIG-YVGGINCAAYTASKAGVAGLTRALARELGPTV--RVNC
Mflv_4505|M.gilvum_PYR-GCK GSIINIASIEG-MAGTVGCHGYTATKFAVRGLTKSTALELGPFG-IRVNS
MAV_2509|M.avium_104 GSIINISSIEG-MAGTIACHGYTATKFAVRGLTKSAALELGPSG-IRVNS
MLBr_01807|M.leprae_Br4923 GRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRS-ITANV
MAB_2723c|M.abscessus_ATCC_199 GRLIFMGSVAG-QIGLPGQANYSASKAGLVGMARALTRELGSRS-ITANV
Mvan_4185|M.vanbaalenii_PYR-1 GRIVMISSSSA-QRGSPGMAHYAASKGALISFTRSLAREYGPAG-ITVNN
. : .* . * :* .: .::: : *
Mb2882c|M.bovis_AF2122/97 LCPGPVNTPLLQELFAKN-PERAARRMVHVPLGRFAEPDEIAAAVAFLAS
Rv2857c|M.tuberculosis_H37Rv LCPGPVNTPLLQELFAKN-PERAARRMVHVPLGRFAEPDEIAAAVAFLAS
MMAR_4927|M.marinum_M IAPGPIDTEATRTVTP---GEFVKDMVKQIPLSRMGTPEDLVGMCLFLLG
MUL_0478|M.ulcerans_Agy99 IAPGPIDTEATRTVTP---GEFVKDMVKQIPLSRMGTPEDLVGMCLFLLG
TH_2623|M.thermoresistible__bu IAPGFFKSEMTDQYKP---G-YLDSQMPRVLMGRTGDPEELAATLVWLVS
MSMEG_4169|M.smegmatis_MC2_155 VAPGPIETPMTAVHAT---PEWVEQKTRSLVMGRFGTPDEVATAVSWLVG
Mflv_4505|M.gilvum_PYR-GCK VHPGLVKTPMA---------DWVPEDIFQSALGRIAQPHEVSNLVVYLAS
MAV_2509|M.avium_104 IHPGLIKTPMT---------EWVPEDIFQSALGRAAEPKEVSNLVVYLAS
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLAS
MAB_2723c|M.abscessus_ATCC_199 VAPGFIDTDMTRELGEK----HVETALTAIPMGRIGEPSEVAGVVSWLAS
Mvan_4185|M.vanbaalenii_PYR-1 VPPSGIETPMQHQSQAAGFLPPNEQMAASIPVGHLGTGDDIAAAVGFLCS
: *. ..: :.: . :: :* .
Mb2882c|M.bovis_AF2122/97 DDASFITASTFLVDGGISSAYVTPL--------------
Rv2857c|M.tuberculosis_H37Rv DDASFITASTFLVDGGISSAYVTPL--------------
MMAR_4927|M.marinum_M DQASWITGQIFNVDGGQIIRS------------------
MUL_0478|M.ulcerans_Agy99 DQASRITGQIFNVDGGQIIRS------------------
TH_2623|M.thermoresistible__bu DAGGYVTGQTIVVDGGITIT-------------------
MSMEG_4169|M.smegmatis_MC2_155 DEASFVTGQTINVNGGGAMP-------------------
Mflv_4505|M.gilvum_PYR-GCK DESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQPEWIT
MAV_2509|M.avium_104 DESSYSTGSEFVVDGGTTAGLGHKDFSNVETDAQPDWVT
MLBr_01807|M.leprae_Br4923 EDAGYISGAVIPVDGGLGMGH------------------
MAB_2723c|M.abscessus_ATCC_199 PDAAYVSGAVIPVDGGLGMGH------------------
Mvan_4185|M.vanbaalenii_PYR-1 EEAGFITGQTLGVNGGSVMA-------------------
.. :. : *:**