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MSAHTEAPTTSPPTTAVSARHRRLLIAVFSISSSMGYIAMIQIIPVILVSMATDLNTSRTAIAAASTVST LIGALAAFPIGRSLDRYGGRAVMTAGAAIGAVAVALWSQATSLQLVYLSSVFIGISITMCTYEAAFAVLV FATGPTHRDRAIIAVAMIAGLATYLVYPILGWMNITLGWRTSLLILAAAFALTSVPAHLWIIPSRSEHRR HIAKNTGVPTGTALRQGRFWLLSIAFVGQAGSVSAFLFLVIAYLQDIGHPMTVATAVPVSIGVMQILSRL VMTTFAARISLVPATAIAFAIQAAGLLALPLAGLSLPLCVLCVAAVGVGQGVGVIARPSILADSFGVAHF ASVLALMTVPIALARAGMPVFAAWLADWRFLAICGVLALIATLALLPLVGNSRCGSDLLRGCQGLDRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4104 | - | - | 100% (418) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_1169 | - | 6e-33 | 28.24% (393) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_5464 | - | 1e-21 | 25.69% (362) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1699c | - | 3e-09 | 24.34% (415) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1096 | - | 1e-12 | 22.90% (393) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1672c | - | 3e-09 | 24.34% (415) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4839c | - | 3e-30 | 28.49% (358) | MFS family transporter |
| M. marinum M | MMAR_0750 | - | 6e-08 | 23.75% (320) | MFS transporter |
| M. avium 104 | MAV_1023 | - | 9e-08 | 26.63% (368) | MFS transporter |
| M. thermoresistible (build 8) | TH_0390 | - | 2e-08 | 24.47% (376) | major facilitator superfamily protein permease |
| M. ulcerans Agy99 | MUL_1382 | - | 5e-07 | 23.57% (314) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_3219 | - | 2e-32 | 27.63% (380) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4839c|M.abscessus_ATCC_199 ------MSTAAVHAQPHSITGLRGVLITLCLTEITSWGVLYYAFPVLAPR
Mvan_3219|M.vanbaalenii_PYR-1 ------MAESDRADR-------RSVLLTLCLTEITSWGVLYYAFSVLSPA
Mb1699c|M.bovis_AF2122/97 ----MATIAASPTHNALGKAARRLLPLLFVLYVINFVDRANISVAALA--
Rv1672c|M.tuberculosis_H37Rv ----MATIAASPTHNALGKAARRLLPLLFVLYVINFVDRANISVAALA--
MMAR_0750|M.marinum_M MTAVAAPAIHDPTASRSLFASRVTVLLAIALSAFTMRSAVTSMAPLLA--
MUL_1382|M.ulcerans_Agy99 -------MIHDPTASRSLFASRVTVLLAIALSAFTMRSAVTSMAPLLA--
MSMEG_4104|M.smegmatis_MC2_155 MSAHTEAPTTSPPTTAVSARHRRLLIAVFSISSSMGYIAMIQIIPVILVS
Mflv_1096|M.gilvum_PYR-GCK ----MGGPVTRFDSAAIAEWRRYGTVPLAAGLGYSMGVIHVYSLGAFMGP
TH_0390|M.thermoresistible__bu -MNPGRRARTAAGDDDERLAVRPWIVWATGLLAYIVAVLDRTTLGVSGLA
MAV_1023|M.avium_104 -----------MTATPRACNRDRVALQAVHFFMADMEAGMGPFLGVLLQ-
MAB_4839c|M.abscessus_ATCC_199 ITADTGWSAPAVTAAFSAALVVAAAAGIGVGRWLDRHGPRWLMTAGSLWG
Mvan_3219|M.vanbaalenii_PYR-1 ICADTGWSAPAVTAAFSAGLVISALLGIPVGRWLDRHGPRWIMTGGSVLG
Mb1699c|M.bovis_AF2122/97 MNADLRLSATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAVVLAW
Rv1672c|M.tuberculosis_H37Rv MNADLRLSATAYGTAAGVFFLGYVLFQVPANAALARFGAGRTLTAVVLAW
MMAR_0750|M.marinum_M RVADTMGFGGTVIGVFGMLPTAMFALAGFAAPLSRRFGPERLALLSVLAT
MUL_1382|M.ulcerans_Agy99 RVADTMGFGGTVIGVFGMLPTAMFALAGFAAPLSRRFGPERLALLSVLAT
MSMEG_4104|M.smegmatis_MC2_155 MATDLNTSRTAIAAASTVSTLIGALAAFPIGRSLDRYGGRAVMTAGAAIG
Mflv_1096|M.gilvum_PYR-GCK LQDEFGWSRAQASVGLTIVGMAAAVAALPIGLMVDRLGPRRVGIIGAGLM
TH_0390|M.thermoresistible__bu AADRFNAAPAALSTFVVLQVIVYALAQVPAGLLLDRFGSKALIVAGAAVM
MAV_1023|M.avium_104 ---SRGWTTGAIGAAMTLGAIVGMVTVAPAGALVDATRHKRGCVIVVGLA
MAB_4839c|M.abscessus_ATCC_199 PAALIGVAMAPNYGWFLAAWLMAGIAMAAVFYPPAFAALTRWYGP-GAVR
Mvan_3219|M.vanbaalenii_PYR-1 SIALAGVAAAPDVVSFTAAWVVAGVAMSAVFYAPAFAALTRYFRP-DAVR
Mb1699c|M.bovis_AF2122/97 GVCSAATALVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPCA-QRAR
Rv1672c|M.tuberculosis_H37Rv GVCSAATALVTSAHTLYLARFALGVAEGGFFPGVIAYLTVWFPCA-QRAR
MMAR_0750|M.marinum_M AAGTAGRSMAS-DTSELMAFTTLALVGMGIANIVIPPLVKKYFND-RVAL
MUL_1382|M.ulcerans_Agy99 AAGTAGRSMAS-DTSELMAFTTLALVGMGIANIVVPPLVKKYFND-RVAL
MSMEG_4104|M.smegmatis_MC2_155 AVAVALWSQATSLQLVYLSSVFIGISITMCTYEAAFAVLVFATGPTHRDR
Mflv_1096|M.gilvum_PYR-GCK AGAFALLGTATGTMGNWILLWSVLAFACFWVQTTVWTSAVASRFETSRGL
TH_0390|M.thermoresistible__bu ATGQLILAFTESLTLAILARAIVGLGDAVTFISVLRLVPHWFRPR-QVPL
MAV_1023|M.avium_104 AVAASAVILTSRQFWTVATAQAVMCISGATIAPAMIGITLGVVGQAAFTR
.
MAB_4839c|M.abscessus_ATCC_199 ALMVLTLVAGLASTVFVP------LTAVLASHMDWRTTYLALAVLLTIIT
Mvan_3219|M.vanbaalenii_PYR-1 ALTALTLAAGLASTVFAP------LTAAISAHMDWRETYLVLAAAMAVIT
Mb1699c|M.bovis_AF2122/97 AVATFLLAIPVANTVGLPLSGLIVGHVHMAGLPGWRAMFVIEALP-ALLL
Rv1672c|M.tuberculosis_H37Rv AVATFLLAIPVANTVGLPLSGLIVGHVHMAGLPGWRAMFVIEALP-ALLL
MMAR_0750|M.marinum_M MSAIYLACLQLGTIMPA------VAAVPLAESYGWRASLAIWALIPAVAV
MUL_1382|M.ulcerans_Agy99 MSAIYLACLQLGTIMPA------VAAVPLAESYGWRASLAIWALIPAVAV
MSMEG_4104|M.smegmatis_MC2_155 AIIAVAMIAGLATYLVYP------ILGWMNITLGWRTSLLILAAAFALTS
Mflv_1096|M.gilvum_PYR-GCK AFAVTLSGGSLAAAVFPP------LATLLIGEWGWRGALFGLGGLWGGLV
TH_0390|M.thermoresistible__bu VTQLTGICGQLGQVLSAV------LFLALLTARGWTPAYLSVVALGVLTI
MAV_1023|M.avium_104 QNGRNQAYNHAGNMAGAA------LGGVAGWVFGYAGIFWLAAGFAVATI
. .:
MAB_4839c|M.abscessus_ATCC_199 VPAHIIGLRRPWP-----------SLPATHLAESPTRIARSR-PFISLII
Mvan_3219|M.vanbaalenii_PYR-1 VPAHFFGLRRPWP-----------HIEHHHLVEPPTRIARSR-QFVALTV
Mb1699c|M.bovis_AF2122/97 APLLRRLLPDNPQRASWLTPEERAELSARLTEDTPAPTGRSSGAGWDLVL
Rv1672c|M.tuberculosis_H37Rv APLLRRLLPDNPQRASWLTPEERAELSARLTEDTPAPTGRSSGAGWDLVL
MMAR_0750|M.marinum_M LPWILVLVRRRTN----------GTDHAARTGKKIGPIWRSP-ISWGLTF
MUL_1382|M.ulcerans_Agy99 LPWILVLVRRRTN----------GTDHAARTGKKIGPIWRSP-ISWGLTF
MSMEG_4104|M.smegmatis_MC2_155 VPAHLWIIPSRSE----------HRRHIAKNTGVPTGTALRQGRFWLLSI
Mflv_1096|M.gilvum_PYR-GCK LIVVLLFFRGAQDDKK-PAPARTVIAPTAAAADLPGVTLAEGLRSATFYK
TH_0390|M.thermoresistible__bu ALTLALVQNTPDG---------RAAPATMGTVREIAASLKTVWLRAGTRL
MAV_1023|M.avium_104 AAVLAIPGGDIDH--------HVARGEARAAGEAPVKAMRVLARSRPLLV
MAB_4839c|M.abscessus_ATCC_199 AFALAS---CASYAVIVNLVPLMNQRG--LDGTVAATALALGGVGQVIGR
Mvan_3219|M.vanbaalenii_PYR-1 AFAMAG---LASYAVIVNLVPLMTAHG--ISTQAAALALGLGGAGQVLGR
Mb1699c|M.bovis_AF2122/97 FAVVYGGLYFALYALQFFLPQLVASLAHGTATLTAATLAALPYGVAALAM
Rv1672c|M.tuberculosis_H37Rv FAVVYGGLYFALYALQFFLPQLVASLAHGTATLTAATLAALPYGVAALAM
MMAR_0750|M.marinum_M MFSMTS---LITYAMFAWLPVIVTSAG-GSEALGGAMVATFS-GVGFLAT
MUL_1382|M.ulcerans_Agy99 MFSMTS---LITYAMFAWLPVIVTSAG-GSEALGGAMVATFS-GVGFLAT
MSMEG_4104|M.smegmatis_MC2_155 AFVGQAG---SVSAFLFLVIAYLQDIG-HPMTVATAVPVSIG-VMQILSR
Mflv_1096|M.gilvum_PYR-GCK LLVAAGLFAFTTLGIVVHLVPILRDAG--AEPLAAAGTAALVGIFSIVGR
TH_0390|M.thermoresistible__bu GFFTHMGTQFSVTVFALMWGVPYLTVGQGLSTQMAGAMLTLSVAVAIVAG
MAV_1023|M.avium_104 LAAAMVLFHLGNAAMLPLYGLAVVATHANPFTTVASTVVVAQAVMVPASL
. . .
MAB_4839c|M.abscessus_ATCC_199 FGYPALAQCISV---VPRTLLIMGVVAATTALLGVFASAVSLIAVAVAAG
Mvan_3219|M.vanbaalenii_PYR-1 LGYQRMVRHLSV---VPRTALIMAGVAVTTALLGLLTSVATLITVAVVAG
Mb1699c|M.bovis_AF2122/97 LAWSHRSIDRSG---AQAGHITLPTTAAGSAALGAALSPMS-PIVTLSW-
Rv1672c|M.tuberculosis_H37Rv LAWSHRSIDRSG---AQAGHITLPTTAAGSAALGAALSPMS-PIVTLSW-
MMAR_0750|M.marinum_M LVTP-RLCARAA---NPFPIVAASALCFLVGFAGLLWAPLTAPIVWAIF-
MUL_1382|M.ulcerans_Agy99 LVTP-RLCARAA---NPFPIVAASALCFLVGFAGLLWAPLTAPIVWAIF-
MSMEG_4104|M.smegmatis_MC2_155 LVMTTFAARISL---VPATAIAFAIQAAGLLALPLAGLSLPLCVLCVAAV
Mflv_1096|M.gilvum_PYR-GCK LGVGLLLDRFPG---RVVGACAYLVPILGCAALLIDGSSPLSQTVAAALF
TH_0390|M.thermoresistible__bu VLIGIFTGRHPHRRSRLVLAIIASNAAAWTAVLALPDRAPLWLLITLIVV
MAV_1023|M.avium_104 LAMRIAATRGYW----PAILIALTALPVRGVLAASVITSWGVIPVQVLDG
. :
MAB_4839c|M.abscessus_ATCC_199 -MARGIMTLLQATAITERWGSTHYG-----HLSGLLTAPIMLTTALAPFT
Mvan_3219|M.vanbaalenii_PYR-1 -VVRGVMTLLQATAVTERWGITHYG-----QLSGILSAPVMLSTALGPFV
Mb1699c|M.bovis_AF2122/97 -LTIAVAGILAAMPAFWSRCTAALAGPRVAVAIATVNAVASLASFAGPYA
Rv1672c|M.tuberculosis_H37Rv -LTIAVAGILAAMPAFWSRCTAALAGPRVAVAIATVNAVASLASFAGPYA
MMAR_0750|M.marinum_M -LGLGPSTFPAAITLINLRSRTESG---SAALSGFTQGMGYLLASPGPLI
MUL_1382|M.ulcerans_Agy99 -LGLGPSTFPAAITLINLRSRTESG---SAALSGFTQGMGYLLASPGPLI
MSMEG_4104|M.smegmatis_MC2_155 GVGQGVGVIARPSILADSFGVAHFA-----SVLALMTVPIALARAGMPVF
Mflv_1096|M.gilvum_PYR-GCK GLTLGAEVDVIAYLASRYFGLRNFG-----GLFGGLVAALSLGTAFGPLA
TH_0390|M.thermoresistible__bu ISVGGPGSMVGFDFARTFNPSATLGTAQGMVNMGGFLASLLVMQAMGQIL
MAV_1023|M.avium_104 IGAGMLSVAVPGLVARILDGTGHIN-----VGQGAVMAAQGLGGALSPVL
. :
MAB_4839c|M.abscessus_ATCC_199 GAALAQLLH----GYPAMFVALGVAGIIGAAAA--------------TAT
Mvan_3219|M.vanbaalenii_PYR-1 GAGLATLLG----GYGAMFVVLGAVALAAALLA--------------TAT
Mb1699c|M.bovis_AF2122/97 TGHLKDATG----TYHLALLTVAAVLAAAAACS---------LLLRHAGR
Rv1672c|M.tuberculosis_H37Rv TGHLKDATG----TYHLALLTVAAVLAAAAACS---------LLLRHAGR
MMAR_0750|M.marinum_M FGILYNATGRWELSFGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSGS
MUL_1382|M.ulcerans_Agy99 FGILYNATGRWELSFGFLLVPLIALLAGGYHACKPRYLEDTLTPSRKSGS
MSMEG_4104|M.smegmatis_MC2_155 AAWLADWRFLAICGVLALIATLALLPLVGNSRC---------------GS
Mflv_1096|M.gilvum_PYR-GCK AGATSDHFGGYTNFLILTMVLMGLSSMALASLK----------PPPVWTV
TH_0390|M.thermoresistible__bu DAAGGYSFDSFRLAWTVQYVVWVVAAVGILITRKKARRQMALEQERMLLE
MAV_1023|M.avium_104 GGAVAQHLGFRAAFLLLAGLSLGALIIWVTFAP---------MLRRAARL
.
MAB_4839c|M.abscessus_ATCC_199 NPSQ-----------------
Mvan_3219|M.vanbaalenii_PYR-1 RVRPVDADG------------
Mb1699c|M.bovis_AF2122/97 TVCANDSEIMLHPSPATPFV-
Rv1672c|M.tuberculosis_H37Rv TVCANDSEIMLHPSPATPFV-
MMAR_0750|M.marinum_M DAVEDVVEGERLQECSTSCA-
MUL_1382|M.ulcerans_Agy99 DAVEDVVEGERLQECSTSCA-
MSMEG_4104|M.smegmatis_MC2_155 DLLRGCQGLDRS---------
Mflv_1096|M.gilvum_PYR-GCK TSPGEDARADRFPQP------
TH_0390|M.thermoresistible__bu SFEPGPRRHTGPDRTNRPHG-
MAV_1023|M.avium_104 PAAPSDRAGAPPTATADNQAK