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MPTVTWARVDPARRAAIVEAAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLYAYIADIANQR VRTHIEGLIRELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATLEVDTDARISVRSVIHRHYLEVL RPLVRDALARGDLRADSDTDALLSLLLMIFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLTAA YSPSLTVEVRKVT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1152 | - | - | 100% (223) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4765 | - | 6e-07 | 29.65% (172) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_0910 | - | 1e-06 | 30.13% (156) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 1e-108 | 91.00% (211) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3060 | - | 3e-90 | 74.54% (216) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 1e-108 | 91.00% (211) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 6e-05 | 25.41% (122) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 9e-10 | 28.74% (167) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_0489 | - | 1e-123 | 99.55% (223) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4938 | - | 1e-106 | 87.85% (214) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 2e-10 | 33.33% (159) | TetR-type regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 4e-08 | 33.04% (112) | TetR-family protein transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3467 | - | 3e-94 | 78.40% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3060|M.gilvum_PYR-GCK --------------------------MPTVTWSRLGADR-----RAAVVA
Mvan_3467|M.vanbaalenii_PYR-1 --------------------------MPTVTWSRLNEDR-----RAAVVA
MUL_1152|M.ulcerans_Agy99 --------------------------MPTVTWARVDPAR-----RAAIVE
MMAR_0489|M.marinum_M --------------------------MPTVTWARVDPAR-----RAAIVE
Mb0237|M.bovis_AF2122/97 --------------------------MPTVTWARVDPAR-----RAAVVE
Rv0232|M.tuberculosis_H37Rv --------------------------MPTVTWARVDPAR-----RAAVVE
MAV_4938|M.avium_104 --------------------------MPTVTWARVDPAR-----RAAIIE
MSMEG_3807|M.smegmatis_MC2_155 -------------------------MTSSVKPARADATRN----REALLA
MAB_4946|M.abscessus_ATCC_1997 ---------------------MEDPAEPPIRMADRQRARRSELVKEEVVE
TH_2255|M.thermoresistible__bu ------------------------------MPERPDPAR------QAILD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKR----RGQLLI
: ::
Mflv_3060|M.gilvum_PYR-GCK AAETEFAAHGFSGGSLNVIARRAGVAKGSLFQYFADKRDLYAHITEVGSQ
Mvan_3467|M.vanbaalenii_PYR-1 AAEAEFAAHGFSQGSLNVIARRAGVAKGSLFQYFADKRDLYAHITDVGSQ
MUL_1152|M.ulcerans_Agy99 AAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLYAYIADIANQ
MMAR_0489|M.marinum_M AAEAEFGAHGFSQGSLNVIARRARVAKGSLFQYFADKRDLYAYIADIASQ
Mb0237|M.bovis_AF2122/97 AAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQ
Rv0232|M.tuberculosis_H37Rv AAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQYFADKRDLYAFIADIASQ
MAV_4938|M.avium_104 AAESEFGAHGFSRGSLNVIARKAGVAKGSLFQYFADKRDLYAFIADIGSQ
MSMEG_3807|M.smegmatis_MC2_155 AAEEEFAERGLA-ASVADIARRAGVAKGTVFRHFPTKEDLIAAIVTAHTA
MAB_4946|M.abscessus_ATCC_1997 AALAEFSERGYHQTSIAHIAERLGTGHSMFYRYFTNKRDILEHVVQHATQ
TH_2255|M.thermoresistible__bu AAVVEFEQHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENA
MLBr_00815|M.leprae_Br4923 VASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMN
.* * :* .: :* : ..: .:: *. : :: :
Mflv_3060|M.gilvum_PYR-GCK RVRRHMEDQIR-ILDPGRPFFEFLTDLLDVWVAYFAEHPQDRALHAAASF
Mvan_3467|M.vanbaalenii_PYR-1 RVRCYMEDQIR-VLDPTRPFFAFLTDLLDVWVAYFAEHPRERSLHAAASF
MUL_1152|M.ulcerans_Agy99 RVRTHIEGLIR-ELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
MMAR_0489|M.marinum_M RVRTHIEGLIR-ELDSSRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
Mb0237|M.bovis_AF2122/97 RVRSYMEDLIR-ELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
Rv0232|M.tuberculosis_H37Rv RVRSYMEDLIR-ELDPNRPFFEFLTDLLDGWVAYFAEHPRERALHAAATL
MAV_4938|M.avium_104 RVRGYIEQLIR-ELDPTRPFFEFLTDLLDGWVAYFADHPHERALHAAATL
MSMEG_3807|M.smegmatis_MC2_155 TLSETARSLVD-APDPGAALLEFLTEAAD--------QRRQHDLTFLQAA
MAB_4946|M.abscessus_ATCC_1997 RTIETLSHTLPGRITSLNEFHDFSVNLGLAYIDLVVADPRLSRLLLQQGA
TH_2255|M.thermoresistible__bu ALFADIAAELK----HSGPQGDYYVEAFTLAILKFRRHRVLHRMITDEPG
MLBr_00815|M.leprae_Br4923 NLVSSVQQALR----TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDN
: . :
Mflv_3060|M.gilvum_PYR-GCK EVDTDARVSVRAVVHRHYLQVLRPLVHAAGTRGDLRPDADTDTMLSLLLM
Mvan_3467|M.vanbaalenii_PYR-1 EVDTDTRVSVRAVIHRHYLEVLRPLVRDARGRGDLRPDADTDALLSLLLM
MUL_1152|M.ulcerans_Agy99 EVDTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLM
MMAR_0489|M.marinum_M EVDTDARISVRSVIHRHYLEVLRPLVRDALARGDLRADSDTDALLSLLLM
Mb0237|M.bovis_AF2122/97 EVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLL
Rv0232|M.tuberculosis_H37Rv EVDTDARISVRSVLHRHYLDVLRPLVRDAHARGDLRADSDTGALMSLLLL
MAV_4938|M.avium_104 EVDTEARISVQNVIHRHYLEVLRPLVRDARLRGDLRADSDTDALLSLLLL
MSMEG_3807|M.smegmatis_MC2_155 SADDSSVTAARDELHG----YVEQLVAAAREAGAIRADVTGTDVF--LLM
MAB_4946|M.abscessus_ATCC_1997 AVDAEMTAQFCGVFDAG-AAVLGGLLRDGIESGYVREDIDVEAVADSVVG
TH_2255|M.thermoresistible__bu FILHLAQQHWGAAVER-----MAEALRVIFPAG-FAERIGEAAVIEFADT
MLBr_00815|M.leprae_Br4923 ITEPRVAAQVRVATES-CIDAVFALISADSRLDPHRARMVAVGLVGISVD
. : : . :
Mflv_3060|M.gilvum_PYR-GCK ILPHLALAPYVRGMDPVLGLDEIAPEQPALVVRRYVAVLAAAFADTPTPG
Mvan_3467|M.vanbaalenii_PYR-1 ILPHLALAPYVRGMDPVLGLDELSPDQPALVVRRYVAVLAAAFA--PQPL
MUL_1152|M.ulcerans_Agy99 IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSP----S
MMAR_0489|M.marinum_M IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLTAAYSP----S
Mb0237|M.bovis_AF2122/97 IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
Rv0232|M.tuberculosis_H37Rv IFPHLALAPYMRGLDPILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPAT
MAV_4938|M.avium_104 IFPHLALAPYMRGLDPVLGLDEPTPEQPALAVRRLVAVLAAAFSP--APA
MSMEG_3807|M.smegmatis_MC2_155 CTP----------IHVVENLPDPSPD----LWQRYLGILFDGLRP--EGA
MAB_4946|M.abscessus_ATCC_1997 IPLG---------ILARYGHE-PNQDILAARVRATADLVCRGIAP-----
TH_2255|M.thermoresistible__bu ILRYAAMALLLPSVQPLDTADDIRAFATRHFLPSLPAALHTGSA------
MLBr_00815|M.leprae_Br4923 CAR------YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------
Mflv_3060|M.gilvum_PYR-GCK PRQPQPKENSHE
Mvan_3467|M.vanbaalenii_PYR-1 TTATPGGAQSHG
MUL_1152|M.ulcerans_Agy99 LTVEVR--KVT-
MMAR_0489|M.marinum_M LTVEVR--KVT-
Mb0237|M.bovis_AF2122/97 NSAQTRSEEIT-
Rv0232|M.tuberculosis_H37Rv NSAQTRSEEIT-
MAV_4938|M.avium_104 HFATPRSEEVT-
MSMEG_3807|M.smegmatis_MC2_155 HPLPQPPPRLT-
MAB_4946|M.abscessus_ATCC_1997 ------------
TH_2255|M.thermoresistible__bu ------------
MLBr_00815|M.leprae_Br4923 ------------