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PGMTSIEGKVRFGVGLGADTTPEDLPGIVDYLESSGADSVWFSELVYSPAVDPFIGMAYTLSRTTRLKAG TSVAILPGRHPVLVAKQVASLAALAPRRVLPAFGLHSALTAERDVFTVPRGRRGAVFDESLELLNAVLRG RDVSFDGEFFKVRSANVQPVPAKPVDIWLGGSGPVALARIGRLADGWLGSFLTPVEAGAARRTIEREAQA AGREIEPDHYGISLAVAAGDIPDDVYDMARRRRPEVDPAELIAADWPTLHRRIDAYVDAGLTKFVVRPVG SGDREAFLERFVGELLPRQN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3544 | - | - | 100% (301) | hypothetical protein MSMEG_3544 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 4e-23 | 30.21% (288) | hydride transferase 1 |
| M. smegmatis MC2 155 | MSMEG_4820 | - | 1e-20 | 37.68% (138) | hypothetical protein MSMEG_4820 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 1e-18 | 34.09% (176) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3246 | - | 1e-108 | 65.41% (292) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0940c | - | 1e-18 | 34.09% (176) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 5e-13 | 25.37% (272) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3792 | - | 4e-15 | 28.80% (316) | luciferase-like protein |
| M. marinum M | MMAR_5009 | - | 2e-20 | 31.84% (201) | oxidoreductase |
| M. avium 104 | MAV_2830 | - | 1e-111 | 67.12% (292) | hypothetical protein MAV_2830 |
| M. thermoresistible (build 8) | TH_3799 | - | 4e-18 | 28.80% (250) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4083 | - | 3e-20 | 31.84% (201) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5752 | - | 3e-18 | 33.33% (165) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3246|M.gilvum_PYR-GCK --------------MKIRFGVGLGAEVA---PPELPAVVDRLESTGVDSL
MAV_2830|M.avium_104 --------------MKIRFGVGLGADNA---PAELGAIVDHLESTGVDSL
MSMEG_3544|M.smegmatis_MC2_155 ------MPGMTSIEGKVRFGVGLGADTT---PEDLPGIVDYLESSGADSV
Mb0965c|M.bovis_AF2122/97 ---MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSKYP
Rv0940c|M.tuberculosis_H37Rv ---MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSKYP
MMAR_5009|M.marinum_M MSPMKYTVSIAMGPIDELIGIAKTAEEVGFDSIALPDSLFYMEKAAADYP
MUL_4083|M.ulcerans_Agy99 ---MKYTVSIAMGPIDELIGIAKTAEEVGFDSIALPDSLFYMEKAAADYP
TH_3799|M.thermoresistible__bu ---VPISYSLELPTHRVEAPDEFVSAEAIAEIVRAAEDCGFSAVHVTDHP
Mvan_5752|M.vanbaalenii_PYR-1 ---MRIGVVFPQTELGGDPGAVRAYGRR-VEELGFTHLLAYDHVVGADPA
MAB_3792|M.abscessus_ATCC_1997 ---MRFSISIPQFDTGSFDGDGVRDYLARAEELGFAGGWTLEQTVG----
MLBr_00269|M.leprae_Br4923 ---------------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSA
Mflv_3246|M.gilvum_PYR-GCK WLSELVY------SSAVEPFVGMAHALGRTSRLKVGTSVAVLPGRH-PVL
MAV_2830|M.avium_104 WFSELVY------SPAVDPVVGMAFALARTHRLKVGTSVAVLPGRH-PVL
MSMEG_3544|M.smegmatis_MC2_155 WFSELVY------SPAVDPFIGMAYTLSRTTRLKAGTSVAILPGRH-PVL
Mb0965c|M.bovis_AF2122/97 YTPDGNREF-MDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIRP-PAL
Rv0940c|M.tuberculosis_H37Rv YTPDGNREF-MDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIRP-PAL
MMAR_5009|M.marinum_M YTPDGSRMW-NQDTPWVDPLIAAAAMGAATSKLRFYTNVLKLGSRN-PLL
MUL_4083|M.ulcerans_Agy99 YTPDGSRMW-NQDTPWVDPLIAAAAMGAATSKLRFYTNVLKLGSRN-PLL
TH_3799|M.thermoresistible__bu -APDARWLD-HGGHHALDPFVALSFAAAATSTIRLLTNVYIAAYRN-PFL
Mvan_5752|M.vanbaalenii_PYR-1 VHTGWSGPY-DVDTTFHEPLVMFGYLAAVTTTLELVTGVIILPQRQ-TAL
MAB_3792|M.abscessus_ATCC_1997 ------------SSPIIAPLELLAYAAACTTRLRLGVAVLVASQHD-PLQ
MLBr_00269|M.leprae_Br4923 TVSDHFQPWRHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAV
.. * : * : .
Mflv_3246|M.gilvum_PYR-GCK VAKQLASLAALAPKRVLPVFGLRSAMPAEREAFV---VPAGRRGAVFDES
MAV_2830|M.avium_104 VAKQLASLAAVAPKRVLPVFGLRSAIPAEREVFV---VPDGERAAVFDES
MSMEG_3544|M.smegmatis_MC2_155 VAKQVASLAALAPRRVLPAFGLHSALTAERDVFT---VPRGRRGAVFDES
Mb0965c|M.bovis_AF2122/97 VAKQAGSLAALIGNRVGLGVGTS-PWPEDYELMG---VPFAKRGKRIDEC
Rv0940c|M.tuberculosis_H37Rv VAKQAGSLAALIGNRVGLGVGTS-PWPEDYELMG---VPFAKRGKRIDEC
MMAR_5009|M.marinum_M LARQVGSVANLTNNRFGFGVGIG-WAPEEFEWCG---VPYRRRGARVDEM
MUL_4083|M.ulcerans_Agy99 LARQVGSVANLTNNRFGFGVGIG-WAPEEFEWCG---VPYRRRGARVDEM
TH_3799|M.thermoresistible__bu GAKSVQSLDVLSGGRLILGTAAG-YLKPEFRALG---VDFDNRGALLDEA
Mvan_5752|M.vanbaalenii_PYR-1 VAKQAAEVDLLSGGRLRFGVGVG-WNAVEYEALG---EQFTNRGTRSEEQ
MAB_3792|M.abscessus_ATCC_1997 LAAAVTAVDRLSHGRLDVGVAPG-GGARNFAAFG---VDKQTFIARFTEG
MLBr_00269|M.leprae_Br4923 IGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRES
. : : *. . *
Mflv_3246|M.gilvum_PYR-GCK LRLLRAS-LEGP-TTFSGEFFSVRDVEVLPKPAS--HLDIWLGGSSRAGY
MAV_2830|M.avium_104 LRLLRAALVEDS-ATFTGRYFSVTGAAVTPKPAP--PLDIWLGGSAPAAL
MSMEG_3544|M.smegmatis_MC2_155 LELLNAVLRGRD-VSFDGEFFKVRSANVQPVPAK--PVDIWLGGSGPVAL
Mb0965c|M.bovis_AF2122/97 IEIVRGLTTGDY-FEFHGEFYDIPKTKMTPAPTQ--PIPILVGGHADAAL
Rv0940c|M.tuberculosis_H37Rv IEIVRGLTTGDY-FEFHGEFYDIPKTKMTPAPTQ--PIPILVGGHADAAL
MMAR_5009|M.marinum_M IDVIKLVLGGGM-VEFHGQFYDFDRLQMSPAPSE--PVPFYVGGHTDVAL
MUL_4083|M.ulcerans_Agy99 IDVIKLVLGGGM-VEFHGQFYDFDRLQMSPAPSE--PVPFYVGGHTDVAL
TH_3799|M.thermoresistible__bu LDVLTQTLRGDD-VAYQGTTFSSRGVRLRPVPER--VPPIWIGGNSKPAV
Mvan_5752|M.vanbaalenii_PYR-1 VELLRQLWTQRT-VTFDGRHHRVTGAGIAPLPVQR-PIPLWIGAAAPRGY
MAB_3792|M.abscessus_ATCC_1997 LDLMKLAWSDEERITFRGRFRDVADLAFQPKPVQRPHPPIWFGGHAPAAL
MLBr_00269|M.leprae_Br4923 VRLMRELWRGDR-VDFDGDYYQLKGASIYDVPEG--GVPIYIAAGGPEVA
: :: : * . * : ...
Mflv_3246|M.gilvum_PYR-GCK RRIGELGDGWLGS--FVTPDEARDAVRTIRAFAEAAGREVPEDHYGINLA
MAV_2830|M.avium_104 RRIGALADGWLGS--FLTPAEARAGREAIERAAAAAGRHIEPDHFGISLA
MSMEG_3544|M.smegmatis_MC2_155 ARIGRLADGWLGS--FLTPVEAGAARRTIEREAQAAGREIEPDHYGISLA
Mb0965c|M.bovis_AF2122/97 RRAARA-DGWMHG--GGDPDELDRLIARVKRLREEAGKTS-PFEIHVISL
Rv0940c|M.tuberculosis_H37Rv RRAARA-DGWMHG--GGDPDELDRLIARVKRLREEAGKTS-PFEIHVISL
MMAR_5009|M.marinum_M RRAARIGDGWTSA--MMTGEQLAETIGKLNQLRAEYGRAEQPFEFQAVCI
MUL_4083|M.ulcerans_Agy99 RRAARIGDGWTSA--MTTGEQLAETIGKLNQLRAEYGRAEQPFEFQAVCI
TH_3799|M.thermoresistible__bu RRAVSRFQGWAPF--NTFGYATASRTAEISTLDELEAAISWARSYAREIG
Mvan_5752|M.vanbaalenii_PYR-1 ARAGRIADGWFPL--VGPGPALDEAKGAVDAAAREAGRDPSEIGMEGRVR
MAB_3792|M.abscessus_ATCC_1997 ARAVRFGDAFLGAG-SSTTAAFAEEVTTIHRELAIQGKDPARFTIGKRVY
MLBr_00269|M.leprae_Br4923 KYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIK
:.: : .
Mflv_3246|M.gilvum_PYR-GCK VGDGDLPAPVIAAIRTRRP---------------------DLDPEELVAR
MAV_2830|M.avium_104 VADGELPPPAIAAVRRRRP---------------------DLDPDELIAS
MSMEG_3544|M.smegmatis_MC2_155 VAAGDIPDDVYDMARRRRP---------------------EVDPAELIAA
Mb0965c|M.bovis_AF2122/97 DGFT-------VDGVKRLE---------------------DKGVTDVIVG
Rv0940c|M.tuberculosis_H37Rv DGFT-------VDGVKRLE---------------------DKGVTDVIVG
MMAR_5009|M.marinum_M DKFG-------VQGHRELA---------------------EAGVTDNIVI
MUL_4083|M.ulcerans_Agy99 DKFG-------VQGHRELA---------------------EAGVTDNIVI
TH_3799|M.thermoresistible__bu RTDP--LDICFSAGNLIDD---------------------NRSLDERQAG
Mvan_5752|M.vanbaalenii_PYR-1 WRHD--------LDQTAAD---------------------IGEWAEHGAS
MAB_3792|M.abscessus_ATCC_1997 LMIDDDRDRAHTRVQTGLRRIYGEMKGIDAVP-------VSGPPEEVAAG
MLBr_00269|M.leprae_Br4923 MSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAK
: .
Mflv_3246|M.gilvum_PYR-GCK DWAQLHRRLDRYIDA-----GLTKFVIRPAGRGSIDAFLDAFVTELLPRE
MAV_2830|M.avium_104 GWDQLHRKLDAYLDA-----GLTKFVIRPAGTAPWDGFLDRFVTELVGRQ
MSMEG_3544|M.smegmatis_MC2_155 DWPTLHRRIDAYVDA-----GLTKFVVRPVGSGDREAFLERFVGELLPRQ
Mb0965c|M.bovis_AF2122/97 FRVPYTMGPDT--------------EPLQTKIRNLEMFAENVIAKV----
Rv0940c|M.tuberculosis_H37Rv FRVPYTMGPDT--------------EPLQTKIRNLEMFAENVIAKV----
MMAR_5009|M.marinum_M PWVFDGLGFD---------------APLGKKQDSMKRFADTYIHSGWQAA
MUL_4083|M.ulcerans_Agy99 PWVFDGLGFD---------------APLGKKQDSMKRFADTYIHSGWQAA
TH_3799|M.thermoresistible__bu IDRMASAGVTWLT-----------VAPGGDDRAELIERARSFAKEFIRG-
Mvan_5752|M.vanbaalenii_PYR-1 HLSVDTMRAG--------------LRTVNEHLAVLEAIADRVGLR-----
MAB_3792|M.abscessus_ATCC_1997 LRAVADAGAEMIL-----------LNPVGKDVAEDREQMERLAAEVIPQL
MLBr_00269|M.leprae_Br4923 RWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRL
Mflv_3246|M.gilvum_PYR-GCK N---
MAV_2830|M.avium_104 N---
MSMEG_3544|M.smegmatis_MC2_155 N---
Mb0965c|M.bovis_AF2122/97 ----
Rv0940c|M.tuberculosis_H37Rv ----
MMAR_5009|M.marinum_M ----
MUL_4083|M.ulcerans_Agy99 ----
TH_3799|M.thermoresistible__bu ----
Mvan_5752|M.vanbaalenii_PYR-1 ----
MAB_3792|M.abscessus_ATCC_1997 A---
MLBr_00269|M.leprae_Br4923 RRLG