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MRIGVVFPQTELGGDPGAVRAYGRRVEELGFTHLLAYDHVVGADPAVHTGWSGPYDVDTTFHEPLVMFGY LAAVTTTLELVTGVIILPQRQTALVAKQAAEVDLLSGGRLRFGVGVGWNAVEYEALGEQFTNRGTRSEEQ VELLRQLWTQRTVTFDGRHHRVTGAGIAPLPVQRPIPLWIGAAAPRGYARAGRIADGWFPLVGPGPALDE AKGAVDAAAREAGRDPSEIGMEGRVRWRHDLDQTAADIGEWAEHGASHLSVDTMRAGLRTVNEHLAVLEA IADRVGLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5752 | - | - | 100% (288) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 3e-28 | 31.65% (278) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 4e-26 | 33.51% (188) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 2e-20 | 29.82% (228) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4839 | - | 5e-30 | 34.66% (251) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 2e-20 | 29.82% (228) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00348 | - | 2e-15 | 33.33% (168) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 3e-36 | 36.59% (287) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1586 | - | 3e-31 | 34.54% (249) | oxidoreductase |
| M. avium 104 | MAV_0122 | - | 1e-119 | 70.21% (282) | hypothetical protein MAV_0122 |
| M. smegmatis MC2 155 | MSMEG_3609 | - | 7e-32 | 34.62% (260) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_2146 | - | 8e-29 | 36.12% (227) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3448 | - | 7e-31 | 33.33% (261) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5752|M.vanbaalenii_PYR-1 ------------------------------MRIGVVFP-----QTELGGD
MAV_0122|M.avium_104 ------------------------------MRIGVVFP-----QTEIGSD
MAB_0366|M.abscessus_ATCC_1997 ------------------------------MKIGVVAPV----ELGVTAE
Mb3106c|M.bovis_AF2122/97 ------------------------------MQFGVLTF-----VTDEGIG
Rv3079c|M.tuberculosis_H37Rv ------------------------------MQFGVLTF-----VTDEGIG
MMAR_1586|M.marinum_M ------------------------------MQLGLHAL-----GIGAGAD
MUL_3448|M.ulcerans_Agy99 ------------------------------MQLGLHAL-----EIGAGAD
Mflv_4839|M.gilvum_PYR-GCK --------------------------------------------------
TH_2146|M.thermoresistible__bu ------------------------------MRFAFTYPMDSHPYHPDLAT
MSMEG_3609|M.smegmatis_MC2_155 MVWGNRVFSRYLFSDTPGAAIEPAIGRCAGYPCHVLGFALPQFGSAAFAA
MLBr_00348|M.leprae_Br4923 -----------------------MVERANAMKLGLQLG------YWAAQP
Mvan_5752|M.vanbaalenii_PYR-1 PGAVRAYGRRVEELGFTHLLAYDHVVGADPAVHTGWSGP-----YDVDTT
MAV_0122|M.avium_104 PAVLRSYAQRVEELGFTHILAYDHVAGADPRVHRGWRGP-----YDIDST
MAB_0366|M.abscessus_ATCC_1997 PDKILEFARAAERLGFSEISVVEHAVVIGDTQSTYPYSPTGQSHLPDDID
Mb3106c|M.bovis_AF2122/97 ---PAELGAALEHRGFESLFLAEHTHIPVN--TQSPYPGGGPIPEKYYR-
Rv3079c|M.tuberculosis_H37Rv ---PAELGAALEHRGFESLFLAEHTHIPVN--TQSPYPGGGPIPEKYYR-
MMAR_1586|M.marinum_M RSMIDAVACAADDAGFATLWAGEHVVMVDRHTSRYPYSEDGVIAIPPQAD
MUL_3448|M.ulcerans_Agy99 RSMIDAVACAADDAGFATLWAGEHVVMVDRHTSRYPYSEDGVIAIPPQAD
Mflv_4839|M.gilvum_PYR-GCK --MIDAVAASAERSGFETLWFGDQVVMADEDGPHHPYRDDGEIPASAQTD
TH_2146|M.thermoresistible__bu GAAVARVAATAETAGFSGFGFTDHPAPTQKWLDHGGHDT-----------
MSMEG_3609|M.smegmatis_MC2_155 GGELARFASTAEQLGAQSLWVGDRLLAAVDPTVGYAGGDTIP---EQFRA
MLBr_00348|M.leprae_Br4923 PGNAAELVAAAEGAGFDAVFTGEAWG------------------------
: * . :
Mvan_5752|M.vanbaalenii_PYR-1 FHEPLVMFGYLAAVTTTLELVTGVIILPQRQTALVAKQAAEVDLLSGGRL
MAV_0122|M.avium_104 FHEPFVLFGYLAAITS-LELVTGVIILPQRQSVLVAKQAAEVDLLTGGRF
MAB_0366|M.abscessus_ATCC_1997 IPDPLELLSFVAAATTTLGLSTGVLVLPDHHPVVLAKRLATLDRLSRGRL
Mb3106c|M.bovis_AF2122/97 TLDPFVALAAAAATTQSLVLGTGIALIPERDPIVTAKEVASLDLVSQGRF
Rv3079c|M.tuberculosis_H37Rv TLDPFVALAAAAATTQSLVLGTGIALIPERDPIVTAKEVASLDLVSQGRF
MMAR_1586|M.marinum_M WLDPMIALSFAAAASSRITVATGVLLLPEHNPVVVAKQAASLDRLSGGRL
MUL_3448|M.ulcerans_Agy99 WLDPMIALSFAAASSSRITVATGVLLLPEHNPVVVAKQAASLDRLSGGRL
Mflv_4839|M.gilvum_PYR-GCK WLDPLIALSFAAAATNRIELATGVLVLPERNPVVTAKQAASLDRMTGGRL
TH_2146|M.thermoresistible__bu -LDPFVAMGFAAAHTTTLRLIPHIVVLPYRNPFVVAKAGASVDLLSGGRF
MSMEG_3609|M.smegmatis_MC2_155 CLDPFTALAVAAAATSTARLGSSVFVAPWYPPVQLARQLASIDAVSGGRL
MLBr_00348|M.leprae_Br4923 -SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRH
:. :. .: : : . : . . * :* :: **
Mvan_5752|M.vanbaalenii_PYR-1 RFGVGVGWNAVEYEALGEQFTNRGTRSEEQVELLRQLWTQR-TVTFDGRH
MAV_0122|M.avium_104 RLGIGLGWNAVEYEALGETFTNRGKRSEEQVELMRRLWTER-SVTFDGKY
MAB_0366|M.abscessus_ATCC_1997 RICAGVGWMREEIEACGGDFDRRGRAADEAIAVMRALWSTDGPTSHDGEF
Mb3106c|M.bovis_AF2122/97 RFGVGVGWLREEVANHGVDPAVRGRVIDERLRAIIEIWTQE-QAEFHGTY
Rv3079c|M.tuberculosis_H37Rv RFGVGVGWLREEVANHGVDPAVRGRVIDERLRAIIEIWTQE-QAEFHGTY
MMAR_1586|M.marinum_M TLGVGVGWSREEFAALGVPFQDRAGRTAEYVAAMRTLWRDD-LASFTGEF
MUL_3448|M.ulcerans_Agy99 TLGVGVGWSREEFAALGVPFQDRVGRTAEYVAAMRTLWRDD-LASFTGEF
Mflv_4839|M.gilvum_PYR-GCK TLGVGIGISPQEYDALGVPFASRGARLAEYVGAMRTLWRDD-DASFAGRY
TH_2146|M.thermoresistible__bu TLGVGVGYLKREFAALGVDFEERAALFEEALEVIRAIWTTD-NVSYTGRH
MSMEG_3609|M.smegmatis_MC2_155 IPGFGIGWSPEEYQAAGAPFDGRGAQLDEILDALEALWTDD-PVRHEGKR
MLBr_00348|M.leprae_Br4923 ILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQH
*:. * * : : :* . *
Mvan_5752|M.vanbaalenii_PYR-1 HRVTGAGIAP-------LPVQRP----IPLWIGAAAPRGYARAGRIADGW
MAV_0122|M.avium_104 HTVTAAGLAP-------LPVQRP----IPVWFGAASDRAFERAGRLGDGW
MAB_0366|M.abscessus_ATCC_1997 YSFRNAYSYP-------KPVRPQG---VPLYIGGHSKAAARRAGRLGSGF
Mb3106c|M.bovis_AF2122/97 VDFDPIYCWP-------KPVTKPY---PPLYVGGGP-ANFPRIARLNAGW
Rv3079c|M.tuberculosis_H37Rv VDFDPIYCWP-------KPVTKPY---PPLYVGGGP-ANFPRIARLNAGW
MMAR_1586|M.marinum_M VRFDSVRVNP-------KPVRDRR---VPVMVGGNSDAALRRVAAWADGW
MUL_3448|M.ulcerans_Agy99 VRFDSVRVNP-------KPVRDRR---VPVMVGGNSDAALRRVAAWADGW
Mflv_4839|M.gilvum_PYR-GCK VAFDGVRANP-------KPQ-GRS---IPVVLGGNSDAALRRVAEWGDGW
TH_2146|M.thermoresistible__bu FTADGITAHP-------HPVTKPH---PPIWIGGNTGAARQRVADHGAGW
MSMEG_3609|M.smegmatis_MC2_155 WSVPESWVGL-------KPVQRPR---LPICLGAFTPAGLRRIGRRGDGW
MLBr_00348|M.leprae_Br4923 YPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGW
* *: .*. . *:
Mvan_5752|M.vanbaalenii_PYR-1 FPLVGPG-----PALDEAKGAVDAAAREAGRDPSEIGMEGRVRWRHDLDQ
MAV_0122|M.avium_104 FPMTEPG-----PGLDHALEQVTRAAEAAGRDPTSLGMEGRVSWTDDRDK
MAB_0366|M.abscessus_ATCC_1997 QPLGLVG-----DDLTAAVGVMRAAAVDAGRDPRGLDLVLGHGLHR-VDQ
Mb3106c|M.bovis_AF2122/97 IAISPS--------PQRLSGPLQRLRAMAGGDVP--VTVCQWGEAAAKDL
Rv3079c|M.tuberculosis_H37Rv IAISPS--------PQRLSGPLQRLRAMAGGDVP--VTVCQWGEAAAKDL
MMAR_1586|M.marinum_M YGFNLDG----VGAVRERVGTLDRLCAESGRNRDELRLSVALRCPQPCDV
MUL_3448|M.ulcerans_Agy99 YGFNLDG----VGAVRERVGTLDRLCAESGRNRDELRLSVALRCPQPCDV
Mflv_4839|M.gilvum_PYR-GCK YGFDLAD----VEEAAFRASKLRSMCREFGRDPTELKLSVALHDPVPADA
TH_2146|M.thermoresistible__bu CPFPAPA----VLAQTARTAAMDSAEALAAGITDLHRRLEATGRDPADVD
MSMEG_3609|M.smegmatis_MC2_155 LPAVFVPGAVSIDALRAQRRVIDAAAEAAGRDPANIATHVRINVAPGSSV
MLBr_00348|M.leprae_Br4923 LPIFFSP-----RMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTE
: .
Mvan_5752|M.vanbaalenii_PYR-1 TAADIGE-------------WAEHGASHLSVDTMRAGLRTVNEHLAVLEA
MAV_0122|M.avium_104 LAGDIAA-------------WRAAGATHLSVNTMKAGFAGVDEHLAALER
MAB_0366|M.abscessus_ATCC_1997 AALDQAA-------------HAGAGRMLLSASRRATTLEAVLEEMAGCAT
Mb3106c|M.bovis_AF2122/97 EGYRHLG-------------VER-VLLELPTEPRDPTLRYLDKLQAELAR
Rv3079c|M.tuberculosis_H37Rv EGYRHLG-------------VER-VLLELPTEPRDPTLRYLDKLQAELAR
MMAR_1586|M.marinum_M DALAELG-------------IDELVLVETPPEAADAAQNWVSALAERWLS
MUL_3448|M.ulcerans_Agy99 DALAELG-------------IDELVLVETPPEAADAAQNWVSALAERWLS
Mflv_4839|M.gilvum_PYR-GCK VRLADAG-------------IDELVLVAGPPADPIAAEAWIADLAGQWMR
TH_2146|M.thermoresistible__bu VVFSNLT-------------GGTPGRADFNADAYLDGVAKLGALGVTWLQ
MSMEG_3609|M.smegmatis_MC2_155 SQVADAV-------------KILAEGGYPDAFVDLMYVETDVDAVLGWVE
MLBr_00348|M.leprae_Br4923 DRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRS
Mvan_5752|M.vanbaalenii_PYR-1 IADRVGLR------------------------------------------
MAV_0122|M.avium_104 VAADLR--------------------------------------------
MAB_0366|M.abscessus_ATCC_1997 RLELGGPR------------------------------------------
Mb3106c|M.bovis_AF2122/97 LA------------------------------------------------
Rv3079c|M.tuberculosis_H37Rv LA------------------------------------------------
MMAR_1586|M.marinum_M TVWVR---------------------------------------------
MUL_3448|M.ulcerans_Agy99 TVWVR---------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK ---VRT--------------------------------------------
TH_2146|M.thermoresistible__bu VPIPGDSLNHALEAIEAFGSEVIGKL------------------------
MSMEG_3609|M.smegmatis_MC2_155 KLVA----------------------------------------------
MLBr_00348|M.leprae_Br4923 NQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVE
Mvan_5752|M.vanbaalenii_PYR-1 ---------
MAV_0122|M.avium_104 ---------
MAB_0366|M.abscessus_ATCC_1997 ---------
Mb3106c|M.bovis_AF2122/97 ---------
Rv3079c|M.tuberculosis_H37Rv ---------
MMAR_1586|M.marinum_M ---------
MUL_3448|M.ulcerans_Agy99 ---------
Mflv_4839|M.gilvum_PYR-GCK ---------
TH_2146|M.thermoresistible__bu ---------
MSMEG_3609|M.smegmatis_MC2_155 ---------
MLBr_00348|M.leprae_Br4923 QVRDLAGLF