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KIRFGVGLGADNAPAELGAIVDHLESTGVDSLWFSELVYSPAVDPVVGMAFALARTHRLKVGTSVAVLPG RHPVLVAKQLASLAAVAPKRVLPVFGLRSAIPAEREVFVVPDGERAAVFDESLRLLRAALVEDSATFTGR YFSVTGAAVTPKPAPPLDIWLGGSAPAALRRIGALADGWLGSFLTPAEARAGREAIERAAAAAGRHIEPD HFGISLAVADGELPPPAIAAVRRRRPDLDPDELIASGWDQLHRKLDAYLDAGLTKFVIRPAGTAPWDGFL DRFVTELVGRQN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2830 | - | - | 100% (293) | hypothetical protein MAV_2830 |
| M. avium 104 | MAV_3045 | - | 3e-21 | 31.69% (243) | hypothetical protein MAV_3045 |
| M. avium 104 | MAV_5129 | - | 8e-20 | 35.76% (165) | hypothetical protein MAV_5129 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 1e-16 | 35.76% (165) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3246 | - | 1e-115 | 72.35% (293) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0940c | - | 1e-16 | 35.76% (165) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 8e-10 | 23.95% (334) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4908c | - | 5e-14 | 35.29% (136) | putative luciferase-like oxidoreductase |
| M. marinum M | MMAR_0393 | - | 9e-22 | 35.55% (211) | hypothetical protein MMAR_0393 |
| M. smegmatis MC2 155 | MSMEG_3544 | - | 1e-111 | 67.12% (292) | hypothetical protein MSMEG_3544 |
| M. thermoresistible (build 8) | TH_3030 | - | 6e-19 | 30.42% (286) | PUTATIVE putative luciferase family protein |
| M. ulcerans Agy99 | MUL_1043 | - | 6e-22 | 35.55% (211) | hypothetical protein MUL_1043 |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 3e-21 | 38.93% (149) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2830|M.avium_104 -----------MKIRFGVGLGADNAPAELG-----------AIVDHLEST
Mflv_3246|M.gilvum_PYR-GCK -----------MKIRFGVGLGAEVAPPELP-----------AVVDRLEST
MSMEG_3544|M.smegmatis_MC2_155 ---MPGMTSIEGKVRFGVGLGADTTPEDLP-----------GIVDYLESS
MMAR_0393|M.marinum_M --MRFIITHPMHSHPYHPELASGAGVAAVA--A-AAERAGFHGFGFTDHP
MUL_1043|M.ulcerans_Agy99 ----------MHSHPYHPELASGAGVAAVA--A-AAERAGFHGFGFTDHP
TH_3030|M.thermoresistible__bu --MHFTLEYPSDVPTANPELREPAVLRALS--V-HAEAVGFDAIALADHP
Mb0965c|M.bovis_AF2122/97 --MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMT-IPDSIAYPFESDSKYP
Rv0940c|M.tuberculosis_H37Rv --MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMT-IPDSIAYPFESDSKYP
Mvan_5167|M.vanbaalenii_PYR-1 MRLVFALPHMLRLPAMSQPWEASVTGADQTRMARCADQWGYDMIAVPEHF
MAB_4908c|M.abscessus_ATCC_199 -----MTGFGISTTSADGYVSPDVLARAVE-------ERGFEWLLFDDHS
MLBr_00269|M.leprae_Br4923 ------MAELRLGYKASAEQFAPRELVELG----------VAAEAHGMDS
MAV_2830|M.avium_104 GVDSLWFSELVYSP------AVDPVVGMAFALARTHRLKVGTSVAVLPGR
Mflv_3246|M.gilvum_PYR-GCK GVDSLWLSELVYSS------AVEPFVGMAHALGRTSRLKVGTSVAVLPGR
MSMEG_3544|M.smegmatis_MC2_155 GADSVWFSELVYSP------AVDPFIGMAYTLSRTTRLKAGTSVAILPGR
MMAR_0393|M.marinum_M -APSQRWLEAGGHD------SLDPFVALGFAAAQTTSLRLIPNIVVLPYR
MUL_1043|M.ulcerans_Agy99 -APSQRWLEAGGHD------SLDPFVALGFAAAQTTSLRLIPNIVVLPYR
TH_3030|M.thermoresistible__bu -APSAKWRRSGGHS------TFDPAVALAFFAAATSTIRLMTHLWVLPFR
Mb0965c|M.bovis_AF2122/97 YTPDGNREFMDGKP------FIETFVLTAALGAVTTRLRFNFFVLKLPIR
Rv0940c|M.tuberculosis_H37Rv YTPDGNREFMDGKP------FIETFVLTAALGAVTTRLRFNFFVLKLPIR
Mvan_5167|M.vanbaalenii_PYR-1 VIPAEH-VELSGPH------YLQSTVAQAYLAGATERIRLNSCITVLPLQ
MAB_4908c|M.abscessus_ATCC_199 YFPVDTPDSIDAEFRARLPLIRDLPVVLAYAASATERLIVGSGVALLPQR
MLBr_00269|M.leprae_Br4923 ATVSDHFQPWRHQGG----HASFSLSWMTAVGERTNRILLGTSVLTPTFR
* : : . :
MAV_2830|M.avium_104 H-PVLVAKQLASLAAVAPKRVLPVFGLRSAIPAEREVFV---VPDGERAA
Mflv_3246|M.gilvum_PYR-GCK H-PVLVAKQLASLAALAPKRVLPVFGLRSAMPAEREAFV---VPAGRRGA
MSMEG_3544|M.smegmatis_MC2_155 H-PVLVAKQVASLAALAPRRVLPAFGLHSALTAERDVFT---VPRGRRGA
MMAR_0393|M.marinum_M N-PFVVAKSAATLDLLSGGRFILAVGVG-YLKREFAALG---VDHAERAE
MUL_1043|M.ulcerans_Agy99 N-PFVVAKSAATLDLLSGGRFILAVGVG-YLKREFAALG---VDHAERAE
TH_3030|M.thermoresistible__bu T-PYLTAKTLSSLDEVSGGRLIAAVGAG-YLRSEFAALG---VEFENRVT
Mb0965c|M.bovis_AF2122/97 P-PALVAKQAGSLAALIGNRVGLGVGTS-PWPEDYELMG---VPFAKRGK
Rv0940c|M.tuberculosis_H37Rv P-PALVAKQAGSLAALIGNRVGLGVGTS-PWPEDYELMG---VPFAKRGK
Mvan_5167|M.vanbaalenii_PYR-1 H-PVVLAKALATADWMSGGRMMVTFGVG-WLQGEFEALG---VPFRERGR
MAB_4908c|M.abscessus_ATCC_199 D-VLHTAKAWATVATLSGGRTVLGVGVG-WNLGEVRNHG---IDPAKRGA
MLBr_00269|M.leprae_Br4923 YNPAVIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFA
.: .: : * .* .*
MAV_2830|M.avium_104 VFDESLRLLRAALVEDSATFTGRYFSVTGAAVTPKPAPP--LDIWLGGSA
Mflv_3246|M.gilvum_PYR-GCK VFDESLRLLRAS-LEGPTTFSGEFFSVRDVEVLPKPASH--LDIWLGGSS
MSMEG_3544|M.smegmatis_MC2_155 VFDESLELLNAVLRGRDVSFDGEFFKVRSANVQPVPAKP--VDIWLGGSG
MMAR_0393|M.marinum_M LFEEALQVIRAVWTSDDISFEGRHFSARGITAHPRPASNPYPPIWVGGNT
MUL_1043|M.ulcerans_Agy99 LFDEALQVIRAVWTSDDISFEGRHFSARGITAHPRPASNPYPPIWVGGNT
TH_3030|M.thermoresistible__bu LFDEYLAALRAIWLHPETPVTGTTFAAAGEMAVTTPVQKPHPPLWIGGNS
Mb0965c|M.bovis_AF2122/97 RIDECIEIVRGLTTGDYFEFHGEFYDIPKTKMTPAPTQP--IPILVGGHA
Rv0940c|M.tuberculosis_H37Rv RIDECIEIVRGLTTGDYFEFHGEFYDIPKTKMTPAPTQP--IPILVGGHA
Mvan_5167|M.vanbaalenii_PYR-1 MADEYLAVIKELWTSDAPSFEGKYVSFREVAFEPKPVQKPHLPIWIGGDA
MAB_4908c|M.abscessus_ATCC_199 VLDEQLAALHALWTQEQAEFHGEHVDFGPVVARPRPARP--LPVHVGGPS
MLBr_00269|M.leprae_Br4923 RLRESVRLMRELWRGDRVDFDGDYYQLKGASIYDVPEGG--VPIYIAAGG
* : :. . * * : :..
MAV_2830|M.avium_104 PAALRRIGALADGWLGSFLTPA--EARAGREAIERAAAAAGRHIEPDHFG
Mflv_3246|M.gilvum_PYR-GCK RAGYRRIGELGDGWLGSFVTPD--EARDAVRTIRAFAEAAGREVPEDHYG
MSMEG_3544|M.smegmatis_MC2_155 PVALARIGRLADGWLGSFLTPV--EAGAARRTIEREAQAAGREIEPDHYG
MMAR_0393|M.marinum_M AAARRRVAAHGDGWCPFPAPAP--LAQTAGTAAIDSADRLAAGIDDLRRK
MUL_1043|M.ulcerans_Agy99 AAARRRVAVHGDGWCPFPAPAP--LAQTAGTAAIDSADRLAAGIDDLRRK
TH_3030|M.thermoresistible__bu PATLRRVVEHGSGWCPMVNPAA--VASSVRTAAIETVDDFARTADKLRQL
Mb0965c|M.bovis_AF2122/97 DAALRRAAR-ADGWMHGGG----------------DPDELDRLIARVKRL
Rv0940c|M.tuberculosis_H37Rv DAALRRAAR-ADGWMHGGG----------------DPDELDRLIARVKRL
Mvan_5167|M.vanbaalenii_PYR-1 DAALRRAAKYASGWWSFLTPPE--KLAERLDFIKSQPDYDGRPFDVVHGL
MAB_4908c|M.abscessus_ATCC_199 RAAQARALRVGDGWLPYAG---------------------TSTPDDVRRA
MLBr_00269|M.leprae_Br4923 PEVAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKM
..*:
MAV_2830|M.avium_104 ISLAVADGELPPPAIAAVRRRR---------------------------P
Mflv_3246|M.gilvum_PYR-GCK INLAVGDGDLPAPVIAAIRTRR---------------------------P
MSMEG_3544|M.smegmatis_MC2_155 ISLAVAAGDIPDDVYDMARRRR---------------------------P
MMAR_0393|M.marinum_M CDAAGRDFSAIDVTFTNFDGGG---------------------------P
MUL_1043|M.ulcerans_Agy99 CDAAGRDFSAIDVTFTNFDGGG---------------------------P
TH_3030|M.thermoresistible__bu LADAGRDPAQIEIQVA---------------------------------V
Mb0965c|M.bovis_AF2122/97 REEAGKT-SPFEIHVISLDGFT---------------------------V
Rv0940c|M.tuberculosis_H37Rv REEAGKT-SPFEIHVISLDGFT---------------------------V
Mvan_5167|M.vanbaalenii_PYR-1 GTNRVGEGHVAQ--------HD---------------------------P
MAB_4908c|M.abscessus_ATCC_199 CGWFAEQ-------------------------------------------
MLBr_00269|M.leprae_Br4923 IEIKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIE
MAV_2830|M.avium_104 DLDPDELIASGWDQLHRKLDAYLDAGLTKFVIRPAGT--APWDGFLDRFV
Mflv_3246|M.gilvum_PYR-GCK DLDPEELVARDWAQLHRRLDRYIDAGLTKFVIRPAGR--GSIDAFLDAFV
MSMEG_3544|M.smegmatis_MC2_155 EVDPAELIAADWPTLHRRIDAYVDAGLTKFVVRPVGS--GDREAFLERFV
MMAR_0393|M.marinum_M ASAD-FNADAYLGGLEKLA----TLGVTWVHVGLPGDGLAHALECIDRFR
MUL_1043|M.ulcerans_Agy99 ASAD-FNADAYLGGLEKLA----MLGVTWVHVGLPGDGLAHALECIDRFR
TH_3030|M.thermoresistible__bu PAVD-FDDAAAVGELDRFVSAVGAAGATRILAHVHASSASAAETYMTRFA
Mb0965c|M.bovis_AF2122/97 DGVKRLEDKGVTDVIVGFR--------VPYTMGPDTEPLQTKIRNLEMFA
Rv0940c|M.tuberculosis_H37Rv DGVKRLEDKGVTDVIVGFR--------VPYTMGPDTEPLQTKIRNLEMFA
Mvan_5167|M.vanbaalenii_PYR-1 DARPGMSAAEIVDRLSWLG---AQGVTVSAVPIPKVRGVEEYLDYAQWVI
MAB_4908c|M.abscessus_ATCC_199 GRADLPVTVSGVPGDHQLAGEYLGAGAERVLFDVHPLNEADTLRALDRLT
MLBr_00269|M.leprae_Br4923 QVAKRWIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDL
MAV_2830|M.avium_104 TELVGRQN
Mflv_3246|M.gilvum_PYR-GCK TELLPREN
MSMEG_3544|M.smegmatis_MC2_155 GELLPRQN
MMAR_0393|M.marinum_M VQVIEAA-
MUL_1043|M.ulcerans_Agy99 VQVIEAA-
TH_3030|M.thermoresistible__bu EHFGL---
Mb0965c|M.bovis_AF2122/97 ENVIAKV-
Rv0940c|M.tuberculosis_H37Rv ENVIAKV-
Mvan_5167|M.vanbaalenii_PYR-1 EEIKPQVP
MAB_4908c|M.abscessus_ATCC_199 EVVARLT-
MLBr_00269|M.leprae_Br4923 APRLRRLG