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QISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVMVDRPRSRYPYSADGRIAVAADADWLDPMI ALSFAAAATSTIRIATGVLLLPEHNPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRGAR TAEYVEAMRTLWRQDVADFTGEFAAFDAVRLHPKPSAGSIPIIVGGNGDRALARVASWGDGWYGFNLDGV AAVGERMDMLRRLCARAGRDVDDLHCAVALQAPAVGDIPALVDLGVDELVIVESPPQDPDVAADWVDALA DRWITCI*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2811 | - | - | 100% (288) | hydride transferase 1 |
M. smegmatis MC2 155 | MSMEG_5520 | - | 6e-34 | 34.85% (264) | hypothetical protein MSMEG_5520 |
M. smegmatis MC2 155 | MSMEG_6621 | - | 3e-32 | 36.25% (251) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3099c | - | 1e-43 | 76.58% (111) | hypothetical protein Mb3099c |
M. gilvum PYR-GCK | Mflv_4839 | - | 1e-88 | 58.21% (268) | luciferase family protein |
M. tuberculosis H37Rv | Rv3072c | - | 2e-43 | 76.58% (111) | hypothetical protein Rv3072c |
M. leprae Br4923 | MLBr_00348 | - | 2e-13 | 31.08% (148) | putative coenzyme F420-dependent oxidoreductase |
M. abscessus ATCC 19977 | MAB_0366 | - | 3e-39 | 40.97% (227) | hypothetical protein MAB_0366 |
M. marinum M | MMAR_1586 | - | 1e-112 | 67.47% (289) | oxidoreductase |
M. avium 104 | MAV_2935 | - | 2e-44 | 37.77% (278) | hypothetical protein MAV_2935 |
M. thermoresistible (build 8) | TH_4081 | - | 2e-37 | 35.93% (270) | PUTATIVE putative hydride transferase 1 |
M. ulcerans Agy99 | MUL_3448 | - | 1e-111 | 66.78% (289) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_4864 | - | 2e-35 | 35.23% (264) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1586|M.marinum_M --------MQLGLHALGIGAGADRSMIDAVACAADDAGFATLWAGEHVVM MUL_3448|M.ulcerans_Agy99 --------MQLGLHALEIGAGADRSMIDAVACAADDAGFATLWAGEHVVM MSMEG_2811|M.smegmatis_MC2_155 --------MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVM Mb3099c|M.bovis_AF2122/97 MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM Rv3072c|M.tuberculosis_H37Rv MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM Mflv_4839|M.gilvum_PYR-GCK -------------------------MIDAVAASAERSGFETLWFGDQVVM MAB_0366|M.abscessus_ATCC_1997 -------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVV MAV_2935|M.avium_104 ------------MAPVADGVTADPDWMVAFARHLEACGFESIVAVEHTVL TH_4081|M.thermoresistible__bu ------------VKFGISLFPLRPRQMVDVAVAAERLGYDSVWLGEHVVT Mvan_4864|M.vanbaalenii_PYR-1 -----------MNYGLVLFTSDRGITPAAAAKLADEHGFETFYVPEHTHI MLBr_00348|M.leprae_Br4923 ---------------------------MVERANAMKLGLQLGYWAAQPPG * : MMAR_1586|M.marinum_M VDRHTSRYPYSED-GVIAIPPQADWLDPMIALSFAAAASSRITVATGVLL MUL_3448|M.ulcerans_Agy99 VDRHTSRYPYSED-GVIAIPPQADWLDPMIALSFAAASSSRITVATGVLL MSMEG_2811|M.smegmatis_MC2_155 VDRPRSRYPYSAD-GRIAVAADADWLDPMIALSFAAAATSTIRIATGVLL Mb3099c|M.bovis_AF2122/97 VDRPASRYPYSRD-GVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLL Rv3072c|M.tuberculosis_H37Rv VDRPASRYPYSRD-GVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLL Mflv_4839|M.gilvum_PYR-GCK ADEDGPHHPYRDD-GEIPASAQTDWLDPLIALSFAAAATNRIELATGVLV MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPT-GQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLV MAV_2935|M.avium_104 LTRYDSVYPYDSS-GRVGLAPDCPIPDPLDLLAFLAGHTTRLGLATGVLV TH_4081|M.thermoresistible__bu PIHSDSTFPYAEDDAHAAFHGQLPFYDPFAALGYLAAQTSTLRLVLSISI Mvan_4864|M.vanbaalenii_PYR-1 PIKRQAAHPTTGD-ESLPDDRYMRTLDPWVSLGTAAAVTSRVRLSTAVAL MLBr_00348|M.leprae_Br4923 NAAELVAAAEGAG-FDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQ . *. *. .. : : : .: MMAR_1586|M.marinum_M LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRAGR MUL_3448|M.ulcerans_Agy99 LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGR MSMEG_2811|M.smegmatis_MC2_155 LPEHNPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRGAR Mb3099c|M.bovis_AF2122/97 LPEHNPVIVAKEAASLDRLSGRRLTLGVAS-------------------- Rv3072c|M.tuberculosis_H37Rv LPEHNPVIVAKEAASLDRLSGRRLTLGVAS-------------------- Mflv_4839|M.gilvum_PYR-GCK LPERNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRGAR MAB_0366|M.abscessus_ATCC_1997 LPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRA MAV_2935|M.avium_104 LPNHHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNRGRR TH_4081|M.thermoresistible__bu VPVHDPFHLARSVTTLDLFSEGRFWFGMGAGWLREEFEILQKPFDGRGRI Mvan_4864|M.vanbaalenii_PYR-1 PVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVPPGRRRTM MLBr_00348|M.leprae_Br4923 LSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSR : * * ::* :: * : . MMAR_1586|M.marinum_M TAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPV----------R MUL_3448|M.ulcerans_Agy99 TAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPV----------R MSMEG_2811|M.smegmatis_MC2_155 TAEYVEAMRTLWRQ---DVADFTGEFAAFDAVRLHPKPS----------A Mb3099c|M.bovis_AF2122/97 -------------------------------------------------- Rv3072c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4839|M.gilvum_PYR-GCK LAEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQ----------G MAB_0366|M.abscessus_ATCC_1997 ADEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPV----------R MAV_2935|M.avium_104 ADEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPV----------A TH_4081|M.thermoresistible__bu LDETIDIMNRLFTQ---DVTTYRGRHFTVPPVGLQPKPL----------T Mvan_4864|M.vanbaalenii_PYR-1 LREYLEAMRALWTQ---EEAEFDGEFVKFGPSWAWPKPV----------Q MLBr_00348|M.leprae_Br4923 TREYIDIVRQVWAR--EAPVVSDGQHYPLPLTGAGATGLGKALKPITHPL MMAR_1586|M.marinum_M DRRVPVMVGGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAE MUL_3448|M.ulcerans_Agy99 DRRVPVMVGGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAE MSMEG_2811|M.smegmatis_MC2_155 G-SIPIIVGGNGDRALARVASWGDGWYGFNLDGVAAVGERMDMLRRLCAR Mb3099c|M.bovis_AF2122/97 -------------------------------DGP-----RRSSTRSECHS Rv3072c|M.tuberculosis_H37Rv -------------------------------DGP-----RRSSTRSECHS Mflv_4839|M.gilvum_PYR-GCK R-SIPVVLGGNSDAALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCRE MAB_0366|M.abscessus_ATCC_1997 PQGVPLYIGGHSKAAARRAGRLGSGFQPLGLVGD-DLTAAVGVMRAAAVD MAV_2935|M.avium_104 AERFPVHIGGHSRAAARRAGRFGDGFQPLGVTGA-RLASLIGLMRDEAVA TH_4081|M.thermoresistible__bu RPHPPYLFGGHSRKALERAAARGQGWLSSGMSPE-RNAEAIAFLRRERRR Mvan_4864|M.vanbaalenii_PYR-1 AHIPVLVGAAGTEKNFKWIAKSADGWITTPRDFT--IDEPVKLLQDTWAA MLBr_00348|M.leprae_Br4923 RADIPIMLGAEGPKNVALAAEICDGWLPIFFSPR-MADMYNEWLDEGFAR MMAR_1586|M.marinum_M SGRNRDELRLSVALRCPQPCDVDALAELGIDELVLVETPPEAADAAQNWV MUL_3448|M.ulcerans_Agy99 SGRNRDELRLSVALRCPQPCDVDALAELGIDELVLVETPPEAADAAQNWV MSMEG_2811|M.smegmatis_MC2_155 AGRDVDDLHCAVALQAPAVGDIPALVDLGVDELVIVESPPQDPDVAADWV Mb3099c|M.bovis_AF2122/97 SGAQS--------------------------------APPNTSLQCAHYG Rv3072c|M.tuberculosis_H37Rv SGAQS--------------------------------APPNTSLQCAHYG Mflv_4839|M.gilvum_PYR-GCK FGRDPTELKLSVALHDPVPADAVRLADAGIDELVLVAGPPADPIAAEAWI MAB_0366|M.abscessus_ATCC_1997 AGRDPRGLDLVLGHGLHRVDQAALDQAAHAGAGRMLLSASRRATTLEAVL MAV_2935|M.avium_104 AGRDPAALEVSLGHSVSKIDAERAARLADQGADRLVLAMPP-TSDIEQAK TH_4081|M.thermoresistible__bu LGVDDQPFECST-HLVGPVDRGLVDAYREAGVDRLVVRPWRKGGQAVEAI Mvan_4864|M.vanbaalenii_PYR-1 AGRDGAPQIVALDFKPDP--EKLAHWREIGVTEVLFGLPDKSEADVAAYV MLBr_00348|M.leprae_Br4923 TGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFH * MMAR_1586|M.marinum_M SALAERWLSTVWVR------------------------------------ MUL_3448|M.ulcerans_Agy99 SALAERWLSTVWVR------------------------------------ MSMEG_2811|M.smegmatis_MC2_155 DALADRWITCI--------------------------------------- Mb3099c|M.bovis_AF2122/97 ATTSHRSTATVGS------------------------------------- Rv3072c|M.tuberculosis_H37Rv ATTSHRSTATVGS------------------------------------- Mflv_4839|M.gilvum_PYR-GCK ADLAGQWMRVRT-------------------------------------- MAB_0366|M.abscessus_ATCC_1997 EEMAGCATRLELG---GPR------------------------------- MAV_2935|M.avium_104 DMLSACAQRLSLRPVSGP-------------------------------- TH_4081|M.thermoresistible__bu TRLADDLGVTRTDRVTDCSTHTI--------------------------- Mvan_4864|M.vanbaalenii_PYR-1 ERLAGKLGALT--------------------------------------- MLBr_00348|M.leprae_Br4923 ADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVC MMAR_1586|M.marinum_M ------------------------------- MUL_3448|M.ulcerans_Agy99 ------------------------------- MSMEG_2811|M.smegmatis_MC2_155 ------------------------------- Mb3099c|M.bovis_AF2122/97 ------------------------------- Rv3072c|M.tuberculosis_H37Rv ------------------------------- Mflv_4839|M.gilvum_PYR-GCK ------------------------------- MAB_0366|M.abscessus_ATCC_1997 ------------------------------- MAV_2935|M.avium_104 ------------------------------- TH_4081|M.thermoresistible__bu ------------------------------- Mvan_4864|M.vanbaalenii_PYR-1 ------------------------------- MLBr_00348|M.leprae_Br4923 KQIAAWSAAGVTMMMVSASSVEQVRDLAGLF