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MSPMKYTVSIAMGPIDELIGIAKTAEEVGFDSIALPDSLFYMEKAAADYPYTPDGSRMWNQDTPWVDPLI AAAAMGAATSKLRFYTNVLKLGSRNPLLLARQVGSVANLTNNRFGFGVGIGWAPEEFEWCGVPYRRRGAR VDEMIDVIKLVLGGGMVEFHGQFYDFDRLQMSPAPSEPVPFYVGGHTDVALRRAARIGDGWTSAMMTGEQ LAETIGKLNQLRAEYGRAEQPFEFQAVCIDKFGVQGHRELAEAGVTDNIVIPWVFDGLGFDAPLGKKQDS MKRFADTYIHSGWQAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5009 | - | - | 100% (296) | oxidoreductase |
| M. marinum M | MMAR_3291 | - | 2e-56 | 40.93% (281) | hypothetical protein MMAR_3291 |
| M. marinum M | MMAR_4568 | - | 7e-54 | 40.89% (291) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 6e-59 | 41.46% (287) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2912 | - | 4e-56 | 39.58% (283) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0940c | - | 6e-59 | 41.46% (287) | oxidoreductase |
| M. leprae Br4923 | MLBr_00269 | - | 5e-10 | 24.50% (200) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2449 | - | 2e-60 | 44.14% (290) | hypothetical protein MAB_2449 |
| M. avium 104 | MAV_1061 | - | 3e-58 | 42.07% (290) | hypothetical protein MAV_1061 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 2e-37 | 34.75% (259) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_2326 | - | 5e-58 | 41.72% (290) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_4083 | - | 1e-173 | 99.66% (293) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3595 | - | 8e-57 | 42.55% (282) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2912|M.gilvum_PYR-GCK -----MKFYVSTAFLDTREAVEIARAADDLGYHGMAIPDHVVNLETLQTP
Mvan_3595|M.vanbaalenii_PYR-1 -----MKFYVSTAFLDTREAVEIAKAADDLGYHGMAIPDHVINLETLQTP
MMAR_5009|M.marinum_M --MSPMKYTVSIAMGPIDELIGIAKTAEEVGFDSIALPDSLFYMEKAAAD
MUL_4083|M.ulcerans_Agy99 -----MKYTVSIAMGPIDELIGIAKTAEEVGFDSIALPDSLFYMEKAAAD
MAV_1061|M.avium_104 -----MRFTYAEAMTDFRYYIPLAKAAEAAGYHAMTIADSIAYPFESDSK
TH_2326|M.thermoresistible__bu -----MRFTYAEAMTDPSYYIPLAQAAEAAGYHAMTIPDSVAYPFESDSK
Mb0965c|M.bovis_AF2122/97 -----MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSK
Rv0940c|M.tuberculosis_H37Rv -----MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSK
MAB_2449|M.abscessus_ATCC_1997 -----MRFTFAEAMTDPSYYIPLAQAAEAAGYDGMTIADSLAYPYESDAK
MSMEG_2811|M.smegmatis_MC2_155 -MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVMVDRPRSR
MLBr_00269|M.leprae_Br4923 MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWRHQGGH
: :. :*: * : .
Mflv_2912|M.gilvum_PYR-GCK YPYTKDGKRRWEAFTDWPDPWVMIGAVALVTSRLHFVTTVYLPAMR-DPY
Mvan_3595|M.vanbaalenii_PYR-1 YPYTKDGQRRWEAFTDWPDPWVMIGAIALATTRLRFVTTVYLPAMR-DPY
MMAR_5009|M.marinum_M YPYTPDGSRMWNQDTPWVDPLIAAAAMGAATSKLRFYTNVLKLGSR-NPL
MUL_4083|M.ulcerans_Agy99 YPYTPDGSRMWNQDTPWVDPLIAAAAMGAATSKLRFYTNVLKLGSR-NPL
MAV_1061|M.avium_104 YPYTPDGSREFLDGKEFIETFVLTSALGAVTSKLRFNFFVLKLPIR-PPA
TH_2326|M.thermoresistible__bu YPYTPDGDREFLDGKAFIESFVLASALCAATTTLRFNFFVLKLPIR-PPA
Mb0965c|M.bovis_AF2122/97 YPYTPDGNREFMDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIR-PPA
Rv0940c|M.tuberculosis_H37Rv YPYTPDGNREFMDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIR-PPA
MAB_2449|M.abscessus_ATCC_1997 YPYTPDGNREFLEGKPFIEALTLTAALGAVTSTLRFNIFVLKLPIR-PPA
MSMEG_2811|M.smegmatis_MC2_155 YPYSADGRIAVAADADWLDPMIALSFAAAATSTIRIATGVLLLPEH-NPV
MLBr_00269|M.leprae_Br4923 ASFS----------------LSWMTAVGERTNRILLGTSVLTPTFRYNPA
.:: *. : : * : *
Mflv_2912|M.gilvum_PYR-GCK SAAKAIGTAAVLASGRLELGIGVGWCR----EEFELLGQQFERRGKRTDE
Mvan_3595|M.vanbaalenii_PYR-1 SAAKAIGTAAVLAGGRLELGVGVGWCR----EEFELLGQQFERRGRRTDE
MMAR_5009|M.marinum_M LLARQVGSVANLTNNRFGFGVGIGWAP----EEFEWCGVPYRRRGARVDE
MUL_4083|M.ulcerans_Agy99 LLARQVGSVANLTNNRFGFGVGIGWAP----EEFEWCGVPYRRRGARVDE
MAV_1061|M.avium_104 LVAKQIGSLAAMTDNRVGFGVGTSPWP----EDYELLGVPFARRGKRMDE
TH_2326|M.thermoresistible__bu LVAKQAGSLAAMFDNRLGLGVGTSPWP----EDYEVMGVPYAKRGKRMDE
Mb0965c|M.bovis_AF2122/97 LVAKQAGSLAALIGNRVGLGVGTSPWP----EDYELMGVPFAKRGKRIDE
Rv0940c|M.tuberculosis_H37Rv LVAKQAGSLAALIGNRVGLGVGTSPWP----EDYELMGVPFAKRGKRIDE
MAB_2449|M.abscessus_ATCC_1997 LVAKQASSIAALTGNRLGLGVGTSPWP----EDYELMNVPFAKRGKRMDE
MSMEG_2811|M.smegmatis_MC2_155 IMAKQAASVDQLSGGRLLLGVGIGWSR----EEFEALGVPFARRGARTAE
MLBr_00269|M.leprae_Br4923 VIGQAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRE
.: .: : .*. :*:* . :: : .* * *
Mflv_2912|M.gilvum_PYR-GCK MLELMKALWSPGWTEFSGEFYTAPRLEMEPTPP--PIPVYVGGLSDIALR
Mvan_3595|M.vanbaalenii_PYR-1 MLELMKALWSPGWTEFSGEFYTAPRMEMEPTPP--PIPIYVGGLSDIALR
MMAR_5009|M.marinum_M MIDVIKLVLGGGMVEFHGQFYDFDRLQMSPAPSE-PVPFYVGGHTDVALR
MUL_4083|M.ulcerans_Agy99 MIDVIKLVLGGGMVEFHGQFYDFDRLQMSPAPSE-PVPFYVGGHTDVALR
MAV_1061|M.avium_104 CIEIIQGLTTGEYFEFHGEFYDIPKTKMTPAPTK-PIPVLVGGHADAALR
TH_2326|M.thermoresistible__bu CIDIIRGLTTGDYFEYHGEFYDIPKTKMTPAPSK-PIPILIGGHADAALR
Mb0965c|M.bovis_AF2122/97 CIEIVRGLTTGDYFEFHGEFYDIPKTKMTPAPTQ-PIPILVGGHADAALR
Rv0940c|M.tuberculosis_H37Rv CIEIVRGLTTGDYFEFHGEFYDIPKTKMTPAPTQ-PIPILVGGHADAALR
MAB_2449|M.abscessus_ATCC_1997 CIEIIQGLTTGDYFEFHGEFYDIPKTKMCPAPTA-PIPILVGGHADAALR
MSMEG_2811|M.smegmatis_MC2_155 YVEAMRTLWRQDVADFTGEFAAFDAVRLHPKPSAGSIPIIVGGNGDRALA
MLBr_00269|M.leprae_Br4923 SVRLMRELWRGDRVDFDGDYYQLKGASIYDVPEG-GVPIYIAAGGPEVAK
: :: : :: *:: : * :*. :.. .
Mflv_2912|M.gilvum_PYR-GCK RAARH-DGWIGDLISLDRAL--ERVSAVRALRAENGLDMDGFEVITPLTD
Mvan_3595|M.vanbaalenii_PYR-1 RAARH-DGWIGDLITTDKAL--ERIATLRGLRAENGLDMHGFEVITPLTD
MMAR_5009|M.marinum_M RAARIGDGWTSAMMTGEQLA--ETIGKLNQLRAEYGRAEQPFEFQAVCID
MUL_4083|M.ulcerans_Agy99 RAARIGDGWTSAMTTGEQLA--ETIGKLNQLRAEYGRAEQPFEFQAVCID
MAV_1061|M.avium_104 RAARL-DGWMHGGGDPEELD--HLLAKLKRFREEAGKTG-PFEIHVISAD
TH_2326|M.thermoresistible__bu RAARN-DGWMHGGGDGEELD--HLLAKLKRFREEAGATG-PFEIHVISMD
Mb0965c|M.bovis_AF2122/97 RAARA-DGWMHGGGDPDELD--RLIARVKRLREEAGKTS-PFEIHVISLD
Rv0940c|M.tuberculosis_H37Rv RAARA-DGWMHGGGDPDELD--RLIARVKRLREEAGKTS-PFEIHVISLD
MAB_2449|M.abscessus_ATCC_1997 RAARC-DGWMHGGG-TEDLD--ELLATLNKFREEEGTVEKPFEVHVISVD
MSMEG_2811|M.smegmatis_MC2_155 RVASWGDGWYGFNLDGVAAVG-ERMDMLRRLCARAGRDVDDLHC-AVALQ
MLBr_00269|M.leprae_Br4923 YAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKM
.. :*: . : : * :.
Mflv_2912|M.gilvum_PYR-GCK AFTPEHYARAA--------------AGGITGIITMPWMFYS-GPD-----
Mvan_3595|M.vanbaalenii_PYR-1 AFTAEHYERAE--------------AGGITGIITMPWMFYS-GPD-----
MMAR_5009|M.marinum_M KFGVQGHRELA--------------EAGVTDNIVIPWVFDGLGFD-----
MUL_4083|M.ulcerans_Agy99 KFGVQGHRELA--------------EAGVTDNIVIPWVFDGLGFD-----
MAV_1061|M.avium_104 AYTPDGIKRLE--------------DKGVTDVIVGFRIPYIKGKDT----
TH_2326|M.thermoresistible__bu AYTVDGIKRLQ--------------DKGVTDVIVGFRVPYIKGPDT----
Mb0965c|M.bovis_AF2122/97 GFTVDGVKRLE--------------DKGVTDVIVGFRVPYTMGPDT----
Rv0940c|M.tuberculosis_H37Rv GFTVDGVKRLE--------------DKGVTDVIVGFRVPYTMGPDT----
MAB_2449|M.abscessus_ATCC_1997 GFTVDGVKRLE--------------DKGVTDVIVGFRIPYIVGPDT----
MSMEG_2811|M.smegmatis_MC2_155 APAVGDIPALV--------------DLGVDELVIVE-------SPP----
MLBr_00269|M.leprae_Br4923 SYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKR
.: :
Mflv_2912|M.gilvum_PYR-GCK ----------------------------APLDQKIDGMRRFREDLGLD--
Mvan_3595|M.vanbaalenii_PYR-1 ----------------------------ASLPDKVDGMRRFRKDLGLD--
MMAR_5009|M.marinum_M ----------------------------APLGKKQDSMKRFADTYIHSGW
MUL_4083|M.ulcerans_Agy99 ----------------------------APLGKKQDSMKRFADTYIHSGW
MAV_1061|M.avium_104 ----------------------------EPLDTKIRNLEMFAENVIAKV-
TH_2326|M.thermoresistible__bu ----------------------------EPLADKIRNLEMFAENVIAKL-
Mb0965c|M.bovis_AF2122/97 ----------------------------EPLQTKIRNLEMFAENVIAKV-
Rv0940c|M.tuberculosis_H37Rv ----------------------------EPLQTKIRNLEMFAENVIAKV-
MAB_2449|M.abscessus_ATCC_1997 ----------------------------EPLDTKIRNLESFAEHVISKVN
MSMEG_2811|M.smegmatis_MC2_155 ----------------------------QDPDVAADWVDALADRWITCI-
MLBr_00269|M.leprae_Br4923 WIVVSDPDEAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLR
: : .
Mflv_2912|M.gilvum_PYR-GCK ---
Mvan_3595|M.vanbaalenii_PYR-1 ---
MMAR_5009|M.marinum_M QAA
MUL_4083|M.ulcerans_Agy99 QAA
MAV_1061|M.avium_104 ---
TH_2326|M.thermoresistible__bu ---
Mb0965c|M.bovis_AF2122/97 ---
Rv0940c|M.tuberculosis_H37Rv ---
MAB_2449|M.abscessus_ATCC_1997 P--
MSMEG_2811|M.smegmatis_MC2_155 ---
MLBr_00269|M.leprae_Br4923 RLG