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MRFSISIPQFDTGSFDGDGVRDYLARAEELGFAGGWTLEQTVGSSPIIAPLELLAYAAACTTRLRLGVAV LVASQHDPLQLAAAVTAVDRLSHGRLDVGVAPGGGARNFAAFGVDKQTFIARFTEGLDLMKLAWSDEERI TFRGRFRDVADLAFQPKPVQRPHPPIWFGGHAPAALARAVRFGDAFLGAGSSTTAAFAEEVTTIHRELAI QGKDPARFTIGKRVYLMIDDDRDRAHTRVQTGLRRIYGEMKGIDAVPVSGPPEEVAAGLRAVADAGAEMI LLNPVGKDVAEDREQMERLAAEVIPQLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3792 | - | - | 100% (308) | luciferase-like protein |
| M. abscessus ATCC 19977 | MAB_0366 | - | 3e-18 | 35.88% (170) | hypothetical protein MAB_0366 |
| M. abscessus ATCC 19977 | MAB_4277 | - | 4e-18 | 28.00% (300) | luciferase-like monooxygenase superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 1e-17 | 36.92% (130) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_4097 | - | 9e-23 | 27.49% (331) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 1e-17 | 36.92% (130) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00131 | - | 6e-11 | 26.11% (157) | putative oxidoreductase |
| M. marinum M | MMAR_1055 | - | 1e-126 | 72.64% (307) | flavin-dependent oxidoreductase |
| M. avium 104 | MAV_4445 | - | 1e-126 | 72.96% (307) | hypothetical protein MAV_4445 |
| M. smegmatis MC2 155 | MSMEG_1475 | - | 1e-126 | 74.43% (305) | hypothetical protein MSMEG_1475 |
| M. thermoresistible (build 8) | TH_2146 | - | 6e-25 | 33.20% (241) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0814 | - | 1e-124 | 71.66% (307) | flavin-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5752 | - | 3e-22 | 30.21% (288) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1055|M.marinum_M ------------------MRFSIAIPQLDTDGFDAAGLRAYLARAEELGF
MUL_0814|M.ulcerans_Agy99 ------------------MRFSIAIPQLDTDGFDAAGLRAYLARAEELGF
MAV_4445|M.avium_104 ------------------MRFSIAIPQFDYDGFDGAGLRSFLTRAEQLGF
MSMEG_1475|M.smegmatis_MC2_155 MTFHMRATLTASRRTVGRVTFSISIPQFDTGRFDASGVKNYLTRAEELGF
MAB_3792|M.abscessus_ATCC_1997 ------------------MRFSISIPQFDTGSFDGDGVRDYLARAEELGF
Mflv_4097|M.gilvum_PYR-GCK --------------MQFAITHPMHSHPYNPELVTGAGIARVAVAAEKAGF
TH_2146|M.thermoresistible__bu --------------MRFAFTYPMDSHPYHPDLATGAAVARVAATAETAGF
Mb0815c|M.bovis_AF2122/97 ----------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGF
Rv0791c|M.tuberculosis_H37Rv ----------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGF
Mvan_5752|M.vanbaalenii_PYR-1 ------------------MRIGVVFPQTELGGDPG-AVRAYGRRVEELGF
MLBr_00131|M.leprae_Br4923 ---------------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGA
. . *
MMAR_1055|M.marinum_M EGGWVLEQIIGSS----------------------------------PLL
MUL_0814|M.ulcerans_Agy99 EGGWGLEQIIGSS----------------------------------PLL
MAV_4445|M.avium_104 EGGWALEQIIGPA----------------------------------PPL
MSMEG_1475|M.smegmatis_MC2_155 EGGWTLEQTVGHA----------------------------------PLI
MAB_3792|M.abscessus_ATCC_1997 AGGWTLEQTVGSS----------------------------------PII
Mflv_4097|M.gilvum_PYR-GCK GGFGFTDHPAPTQRWLEAGGH--------------------------DAL
TH_2146|M.thermoresistible__bu SGFGFTDHPAPTQKWLDHGGH--------------------------DTL
Mb0815c|M.bovis_AF2122/97 DSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLL
Rv0791c|M.tuberculosis_H37Rv DSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLL
Mvan_5752|M.vanbaalenii_PYR-1 THLLAYDHVVGADPAVHTGWSG-------------------PYDVDTTFH
MLBr_00131|M.leprae_Br4923 DSYWVGDHLNALVPRSVATPKYLG-------------VAAKVVPKIDANY
::
MMAR_1055|M.marinum_M APLELLAYCAACTNR--LRLGVAVLVTSLHDPLQLASSVTAVDRLSNGRL
MUL_0814|M.ulcerans_Agy99 APLQLLAYCAACTNR--LRLGVAVLVTSLHDPLQLASSVTAVDRLSNGRL
MAV_4445|M.avium_104 APLELLAYCAACTER--LRLGVAVLVTSLHDPLQLASAVTAVDRLSHGRL
MSMEG_1475|M.smegmatis_MC2_155 APLELLSYAAAVTTR--LRLGVAVLVTSLHDPLQLASSITAVDRLSHGRL
MAB_3792|M.abscessus_ATCC_1997 APLELLAYAAACTTR--LRLGVAVLVASQHDPLQLAAAVTAVDRLSHGRL
Mflv_4097|M.gilvum_PYR-GCK DPFVAMGFAAAHTTT--LRLIPNIVVLPYRNPFVVAKAGATLDLISDGRF
TH_2146|M.thermoresistible__bu DPFVAMGFAAAHTTT--LRLIPHIVVLPYRNPFVVAKAGASVDLLSGGRF
Mb0815c|M.bovis_AF2122/97 ECWTALAALSRDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRL
Rv0791c|M.tuberculosis_H37Rv ECWTALAALSRDTTK--LRLGTSVLCNSYRHPSVLAKMAATLDVISQGRL
Mvan_5752|M.vanbaalenii_PYR-1 EPLVMFGYLAAVTTT--LELVTGVIILPQRQTALVAKQAAEVDLLSGGRL
MLBr_00131|M.leprae_Br4923 EPWTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKA
:. : . *.* : :.. * : :. :: *:
MMAR_1055|M.marinum_M DLGVAAGGGSRKFAAFGVDR---ATHVSYFTEGLQLMKAAWS-DEPRVRF
MUL_0814|M.ulcerans_Agy99 DLGVAAGGGSRKFAAFGVDR---ATHVSYFTEGLQLMKAAWS-DEPRVRF
MAV_4445|M.avium_104 DIGVAPGGGTRKFAAFGVDK---DTFVAYFTEGLKLMKAAWS-DDPRVTF
MSMEG_1475|M.smegmatis_MC2_155 DVGVAPGGGSRQFRAFGVDP---STFIANFTEGLALMKAAWS-DEPRVTF
MAB_3792|M.abscessus_ATCC_1997 DVGVAPGGGARNFAAFGVDK---QTFIARFTEGLDLMKLAWS-DEERITF
Mflv_4097|M.gilvum_PYR-GCK TLAVGVGYLKREFAALGVEF---DERAAVFEEALDVITQIWT-TDD-LSY
TH_2146|M.thermoresistible__bu TLGVGVGYLKREFAALGVDF---EERAALFEEALEVIRAIWT-TDN-VSY
Mb0815c|M.bovis_AF2122/97 DLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWT-EPN-PTY
Rv0791c|M.tuberculosis_H37Rv DLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWT-EPN-PTY
Mvan_5752|M.vanbaalenii_PYR-1 RFGVGVGWNAVEYEALGEQF---TNRGTRSEEQVELLRQLWT-QRT-VTF
MLBr_00131|M.leprae_Br4923 MLGIGVG-EREGNEPYGVEW---TKPVARFQEALATIRALWDSNGELVSR
..:. * . * : * : : *
MMAR_1055|M.marinum_M HGRFRDVDDLPIQPKPVQRPHPPIWFGGRAPKALARAVRHGDAFLGAGSS
MUL_0814|M.ulcerans_Agy99 HGRFRDVDDLPIQPKRVQRPHPPIWFGGRAPKALARAVRHGDAFLGAGSS
MAV_4445|M.avium_104 HGRFRDVDDLPIAPKPVQRPHPPIWFGGLAPKALARAVRHGDAFMGAGSS
MSMEG_1475|M.smegmatis_MC2_155 HGRFRDVDGLPITPKPVQRPHPPIWFGANAPKALARAVRLGDAFLGAGSS
MAB_3792|M.abscessus_ATCC_1997 RGRFRDVADLAFQPKPVQRPHPPIWFGGHAPAALARAVRFGDAFLGAGSS
Mflv_4097|M.gilvum_PYR-GCK DGRNFSAKGITAHPKPLTTPHPPIWVGGNTSAARARVAKYAQGWC-----
TH_2146|M.thermoresistible__bu TGRHFTADGITAHPHPVTKPHPPIWIGGNTGAARQRVADHGAGWC-----
Mb0815c|M.bovis_AF2122/97 AGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLN-VRWW
Rv0791c|M.tuberculosis_H37Rv AGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLN-VRWW
Mvan_5752|M.vanbaalenii_PYR-1 DGRHHRVTGAGIAPLPVQRPIP-LWIGAAAPRGYARAGRIADGWFPLVGP
MLBr_00131|M.leprae_Br4923 ESQFFPLHNALFDLPPYRGKWPEIWVAAHGPRMLQATGRYADAWIPIVLV
.: . * :*... . . .
MMAR_1055|M.marinum_M TTADFATAVTTLRHELAEQGRDPAGFTIGKRVYLMVDDDPERARERVLAG
MUL_0814|M.ulcerans_Agy99 TTADFATAVTTLRHELAEQGRDPAGFTIGKRVYLMVDDDPERARERVLAG
MAV_4445|M.avium_104 TTEAFAGAVAVLRRELDEQQRDPAEFTIGKRVYLTVDDDAARARERVLAG
MSMEG_1475|M.smegmatis_MC2_155 TTAHFAEAVRIVREELDKQGKDPQSFRIGKRVYLIVDDDGARARERVAEG
MAB_3792|M.abscessus_ATCC_1997 TTAAFAEEVTTIHRELAIQGKDPARFTIGKRVYLMIDDDRDRAHTRVQTG
Mflv_4097|M.gilvum_PYR-GCK ---PFRAPAMLAQTARTAALETTEHLAKGIDDLRRRLEDAGRDPADVDIT
TH_2146|M.thermoresistible__bu ---PFPAPAVLAQTARTAAMDSAEALAAGITDLHRRLEATGRDPADVDVV
Mb0815c|M.bovis_AF2122/97 SPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQ-SGEEEVRIREE
Rv0791c|M.tuberculosis_H37Rv SPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQ-SGEEEVRIREE
Mvan_5752|M.vanbaalenii_PYR-1 GP-ALDEAKGAVDAAAREAGRDPSEIGMEGRVRWRHDL------------
MLBr_00131|M.leprae_Br4923 RPTDYSCALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVDEALDSV
. :
MMAR_1055|M.marinum_M LRSIYGK-------------------------------------------
MUL_0814|M.ulcerans_Agy99 LRSIYGK-------------------------------------------
MAV_4445|M.avium_104 LSRIYGR-------------------------------------------
MSMEG_1475|M.smegmatis_MC2_155 LRRIYGP-------------------------------------------
MAB_3792|M.abscessus_ATCC_1997 LRRIYGE-------------------------------------------
Mflv_4097|M.gilvum_PYR-GCK FTNDAGG-------------------------------------------
TH_2146|M.thermoresistible__bu FSNLTGG-------------------------------------------
Mb0815c|M.bovis_AF2122/97 FASIP---------------------------------------------
Rv0791c|M.tuberculosis_H37Rv FASIP---------------------------------------------
Mvan_5752|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_00131|M.leprae_Br4923 LVRMIALGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKV
MMAR_1055|M.marinum_M -MGGLDAVAVAGTPDDVTRGLAEVIAAGAQTLLLNPVGPDVGQNHEQMER
MUL_0814|M.ulcerans_Agy99 -MGGLDAVAVAGTPDDVTRGLAEVIAAGAQTLLLNPVGPDVGQNHEQTER
MAV_4445|M.avium_104 -MPGVADVPVSGTPGDVVRGLREVIDAGAQTLLLNPVGADVAENHEQMER
MSMEG_1475|M.smegmatis_MC2_155 -KADYADVAVAGTPGEVVRGLREVIEAGAQTVLLNPTGVDVAEDREQMER
MAB_3792|M.abscessus_ATCC_1997 -MKGIDAVPVSGPPEEVAAGLRAVADAGAEMILLNPVGKDVAEDREQMER
Mflv_4097|M.gilvum_PYR-GCK -APGTDDFNA----DEFLAGAEELERAGVTWLQVNVPGDSLAHAVEAIEG
TH_2146|M.thermoresistible__bu -TPGRADFNA----DAYLDGVAKLGALGVTWLQVPIPGDSLNHALEAIEA
Mb0815c|M.bovis_AF2122/97 -----EPGLIVGTPDRCVERIREYQDRGVGHFLFTIP---HVVKSDYLHI
Rv0791c|M.tuberculosis_H37Rv -----EPGLIVGTPDRCVERIREYQDRGVGHFLFTIP---HVVKSDYLHI
Mvan_5752|M.vanbaalenii_PYR-1 --------------DQTAADIGEWAEHGASHLSVDTMRAGLRTVNEHLAV
MLBr_00131|M.leprae_Br4923 PAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSA
* . . .
MMAR_1055|M.marinum_M LAAEVIPRLR------
MUL_0814|M.ulcerans_Agy99 LAAEVIPRLR------
MAV_4445|M.avium_104 LAAEVIPQLN------
MSMEG_1475|M.smegmatis_MC2_155 LAAEVIPQLT------
MAB_3792|M.abscessus_ATCC_1997 LAAEVIPQLA------
Mflv_4097|M.gilvum_PYR-GCK FGETVIAQR-------
TH_2146|M.thermoresistible__bu FGSEVIGKL-------
Mb0815c|M.bovis_AF2122/97 IGSDIIPRVKTEVTIP
Rv0791c|M.tuberculosis_H37Rv IGSDIIPRVKTEVTIP
Mvan_5752|M.vanbaalenii_PYR-1 LEAIADRVGLR-----
MLBr_00131|M.leprae_Br4923 LLPHARVLRGLKKL--
: