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TEPIAAQQIRFITRLGAAMGAAHYPVSLIRQMLDRASSAYGVRNDFIALPNYVQVVGPTGAHGTIVEAAH LDHELRFAQMFPLARLVRDAMRGAVRPDDGEAQLDRVLEMPDRFPGWVAVVGYGVQSAGLALVLEPTALN LLVATVLGFLVGLFHVVVQRAGMLQHLLPAVSAFTVTAICLLGAHRLGMDHVNLRALIPPLAMFLPGAAI TLAVVELTARDVISGTSRLIAGFVQIAQLAFGILIATQFLGVDGSSLSTDAVNKIGPWAPWLGVLVYAIG VLLFLAPPLSFLPWLVVICYTAFAAQYLGGTVLGSYASGFCGGLVLTVSALAISRRRGAPPTITLILPGF WLLVPGSMGLIGVTELFGADGDSAFPATVISMISVALGLQAGLVLWQLLRLRRSTAPQRAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3837 | - | - | 100% (413) | hypothetical protein MSMEG_3837 |
| M. smegmatis MC2 155 | MSMEG_3459 | - | 2e-14 | 26.10% (341) | hypothetical protein MSMEG_3459 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3764 | - | 2e-09 | 23.28% (335) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0954 | - | 1e-10 | 24.11% (336) | hypothetical protein Mflv_0954 |
| M. tuberculosis H37Rv | Rv3737 | - | 2e-09 | 23.28% (335) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0256c | - | 7e-41 | 29.15% (398) | hypothetical protein MAB_0256c |
| M. marinum M | MMAR_3034 | - | 3e-09 | 22.42% (339) | transmembrane protein |
| M. avium 104 | MAV_3251 | - | 1e-06 | 25.45% (220) | ABC transporter efflux protein, DrrB family protein |
| M. thermoresistible (build 8) | TH_0574 | - | 1e-151 | 67.66% (402) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2274 | - | 2e-09 | 22.42% (339) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_5838 | - | 3e-12 | 25.07% (351) | hypothetical protein Mvan_5838 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3837|M.smegmatis_MC2_155 --------------------------------------------------
TH_0574|M.thermoresistible__bu --------------------------------------------------
Mflv_0954|M.gilvum_PYR-GCK ---MLPSPMVPSRQPRTPVPFRRASVSWPPMEPDSTPRFRRGLRIAMRGR
Mvan_5838|M.vanbaalenii_PYR-1 --------MGSDR-------------------SDGMARRRRALHFALKGR
Mb3764|M.bovis_AF2122/97 ---------------------------MDQDRSDNTA-LRRGLRIALRGR
Rv3737|M.tuberculosis_H37Rv ---------------------------MDQDRSDNTA-LRRGLRIALRGR
MMAR_3034|M.marinum_M MGGLAPRTVVAVVFAVRGSPSKISILPGVQDRLDGVAGSRRGLRIALRGR
MUL_2274|M.ulcerans_Agy99 ----------------------------MQDRLDGVAGSRRGLRIALRGR
MAB_0256c|M.abscessus_ATCC_199 --------------------------------MTALPRRGRALALVRKTL
MAV_3251|M.avium_104 --------------------------------------------------
MSMEG_3837|M.smegmatis_MC2_155 -----------------MTEPIAAQQIRFITRLGAAMGAAHYPVSLIRQM
TH_0574|M.thermoresistible__bu ------------------MEHPADPQVRFLARLGAAMGAANYPVTLIRQM
Mflv_0954|M.gilvum_PYR-GCK RDPATGAGQRSRRPQNTSDERHTRKVLDLTVRLAEVMLSAGSGSADVVAT
Mvan_5838|M.vanbaalenii_PYR-1 RDPASGAGQR-RRTSGRLSERHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Mb3764|M.bovis_AF2122/97 RDPLPVAGRRSRTSGG-IGDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
Rv3737|M.tuberculosis_H37Rv RDPLPVAGRRSRTSGG-IDDLHTRKVLDLTIRLAEVMLSSGSGTADVVAT
MMAR_3034|M.marinum_M RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MUL_2274|M.ulcerans_Agy99 RDPVPVAGQRSRTSSG-MGDQHVRKVLDLTIRLAEVMLSSGSGTADVVAT
MAB_0256c|M.abscessus_ATCC_199 KDKP--------VPLADARHFPDAEVVTMLRMLGIAMLEVGQPTNLVLAK
MAV_3251|M.avium_104 --------------------------------------------------
MSMEG_3837|M.smegmatis_MC2_155 LDRASSAYGVRNDFIALPNYVQVVGPTGAHGTIVEAAHLDHELR---FAQ
TH_0574|M.thermoresistible__bu LDRASAAYGTSHEVVALPNSVQVTGPAPG-GTATAAAHQDAELR---FDQ
Mflv_0954|M.gilvum_PYR-GCK AQDVAQAYRLNDCVVDVFVTTVFVSAPPTTESPAVTIVRSVRARSTDYSR
Mvan_5838|M.vanbaalenii_PYR-1 AQDVAQAYQLTDCVVDVFVTTIFVSALPTADSPPVTIVRAVQARSTDYTR
Mb3764|M.bovis_AF2122/97 AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
Rv3737|M.tuberculosis_H37Rv AQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSR
MMAR_3034|M.marinum_M ANDVAQAYQITDCVVDITVTTIIVSALPTAESAPVTIVRSVRTRSTNFTR
MUL_2274|M.ulcerans_Agy99 ANDVAQAYQITDCVVDITVTTIIVSALPTAESTPVTIVRSVRTRSTNFTR
MAB_0256c|M.abscessus_ATCC_199 LHDIAPQYTDKELRAVVLPTVLIIQIDGVTGQLEVEESTRNTAQ---LDQ
MAV_3251|M.avium_104 --------------------------------------------------
MSMEG_3837|M.smegmatis_MC2_155 MFPLARLVRDAMRGAVRPDDGEAQLDRVLEMPDRFPGWVAVVGYGVQSAG
TH_0574|M.thermoresistible__bu MFPLARLVSAAMRGAVSPTDGNDRLDRILARPAPYPPWLTVLGYGVWSTG
Mflv_0954|M.gilvum_PYR-GCK LAALDELVRRITSGGVSVDQAHDAMDELSERPHPYPRWVATAGWAGFALG
Mvan_5838|M.vanbaalenii_PYR-1 LADLDRLVRRITSGGVSVDEAHEAMDELSEQPHPYPRWIATAGWAGFALG
Mb3764|M.bovis_AF2122/97 LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
Rv3737|M.tuberculosis_H37Rv LAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALG
MMAR_3034|M.marinum_M LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
MUL_2274|M.ulcerans_Agy99 LAELDRLVQEITAGGVTVDEAHEAMDELTQRPHPYPRWLATVCWAGFSLG
MAB_0256c|M.abscessus_ATCC_199 AGHIDAIADMAVVGAIAPADAIARIYEIRCLKPRFGTVLTVVGHTILTLG
MAV_3251|M.avium_104 MSALAALTERSLKSAARDGE----------------MIFEILSPAAYLAG
: :. .. : . *
MSMEG_3837|M.smegmatis_MC2_155 LALVLEPTALNLLVATVLGFLVGLFHVVVQRAGMLQHLLPAVSAFTVTAI
TH_0574|M.thermoresistible__bu LGLVLEPSPLNLLGAAALGLIVGVLAVAGQRFGQLGPLVPVTAAFVVATV
Mflv_0954|M.gilvum_PYR-GCK IAILLGGNWLVCLLAAATSAVIDQTGRRLNRAGTPLFFQQVAGALIATLV
Mvan_5838|M.vanbaalenii_PYR-1 IAMLLGGTWLTCILAAGTSVLIDRSGRLLNRVGTPMFFQQAAGASIATLV
Mb3764|M.bovis_AF2122/97 VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLV
Rv3737|M.tuberculosis_H37Rv VAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLV
MMAR_3034|M.marinum_M IAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLV
MUL_2274|M.ulcerans_Agy99 IAMMLGANWRTCAIAALTAATIDRLGRVLNRIGTPYFFQRVTGAAVATLV
MAB_0256c|M.abscessus_ATCC_199 FGLALAPTSSALPAYLVLGLIVGVLMLATNPMPTLAATMPAVAAFVVTVI
MAV_3251|M.avium_104 FSVALHG------------------LIDTGRISYSQYLLPAVVAQSMIFV
..: * . * :
MSMEG_3837|M.smegmatis_MC2_155 CLLGAHRLGMDHVNLRALIPPLAMFLPGAAITLAVVELTARDVISGTSRL
TH_0574|M.thermoresistible__bu SIAVVEHLELDHVGLRALIPPLAMFLPGAAITLAVIELTARDIVSGSARL
Mflv_0954|M.gilvum_PYR-GCK AVAAYRLAGLGPTALVATG--IVMLLSGMTLVGSVQDALTGYMITAAARL
Mvan_5838|M.vanbaalenii_PYR-1 AVAAFLFAGQGPTTLVATG--IVMLLAGMTLVGSVQDALTGYMLTAVARL
Mb3764|M.bovis_AF2122/97 AVAAYLIAGQDPTALVATG--IVVLLSGMTLVGSMQDAVTGYMLTALARL
Rv3737|M.tuberculosis_H37Rv AVAAYLIAGQDPTALVATG--IVVLLSGMTLVGSMQDAVTGYMLTALARL
MMAR_3034|M.marinum_M AVAAYLFTGEGLAALVATG--IVMLLSGLTLVGAMQDAITGYMVTAVARI
MUL_2274|M.ulcerans_Agy99 AVAAYLFTGEGLAALVATG--IVMLLSGLTLVGAMQDAITGYMVTAVARI
MAB_0256c|M.abscessus_ATCC_199 STLIVANVPSEGLARVLAP-ALIAVLPGMTLTIGALELTSTQLMAGSTRI
MAV_3251|M.avium_104 GLMTADRAARDHLFGFGER----------IRTLPVPAAATVTARVTATLM
. : : :
MSMEG_3837|M.smegmatis_MC2_155 IAGFVQIAQLAFGILIATQFLGVD--GSSLSTDAVNKIGPWAPWLGVLVY
TH_0574|M.thermoresistible__bu MAGFVQLAQLAFGILIAAQLLGED--ESRLSAEPLNKLGSWAPWLGVAVY
Mflv_0954|M.gilvum_PYR-GCK GEVLFLTAGIVVGILAGLQVASLAGITIELQVDATEIMVLPNQPASIAWA
Mvan_5838|M.vanbaalenii_PYR-1 GDVLFLTLGIVVGILAGLQIAALAGIQIQLRVDATEYFVVPTTPRQIVVA
Mb3764|M.bovis_AF2122/97 GDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVA
Rv3737|M.tuberculosis_H37Rv GDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVA
MMAR_3034|M.marinum_M GEALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLT
MUL_2274|M.ulcerans_Agy99 GEALFLTSGIVVGILAGLQIAKTAGVEIELRVHGSGGFVVPQGPLPILLT
MAB_0256c|M.abscessus_ATCC_199 VYGIAQLMLLALGVVIGVKVAGPP-----QPSPLGPPLGSWTIALAVPVI
MAV_3251|M.avium_104 RGSFCLVMALVAGYVLGFRLAGGL--------------------------
: :. * : . :
MSMEG_3837|M.smegmatis_MC2_155 AIGVLLF--------LAPPLSFLPWLVVICYTAFAAQYLGGTVLGSYASG
TH_0574|M.thermoresistible__bu ALGVMLF--------FAPPRSFLPWLLAVCYAAFTAQFLGDLALGSYASG
Mflv_0954|M.gilvum_PYR-GCK VFGATVAGACLTIASYARLRAVATAGLAAGLAELVLIALWSGGLGSVIAT
Mvan_5838|M.vanbaalenii_PYR-1 VSGAALAGACLVIASYAKWRSVLTAGVAAGLAEAVLIGLGRAGVGQVVAT
Mb3764|M.bovis_AF2122/97 VSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVAT
Rv3737|M.tuberculosis_H37Rv VSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVAT
MMAR_3034|M.marinum_M VLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIAT
MUL_2274|M.ulcerans_Agy99 VLGAMLAGACLTVASYAPLRSAVTAGFAAGLADLVLIGLGTAGFGQVIAT
MAB_0256c|M.abscessus_ATCC_199 AVGFYLY--------KSAPRGSLIWLVLAIGVAMLGQRLGSLFLAPAMTG
MAV_3251|M.avium_104 --------------------VYSAAFVFISLLLCLAVTLGADALGSSAKS
. * ..
MSMEG_3837|M.smegmatis_MC2_155 FCGGLVLTVSALAISRRRGAPPTITLILPGFWLLVPGSMGLIGVTELFGA
TH_0574|M.thermoresistible__bu FAGGLVLTGCALMLSRRPGAPPAITMILPGFWLLVPGSMGLIGFAELFGA
Mflv_0954|M.gilvum_PYR-GCK GCAAVGVGFLATLISIRR-QAPALVTATAGITPMLPGMAVFRAVFYFAVE
Mvan_5838|M.vanbaalenii_PYR-1 GTAAVGVGLLATLISIRR-QAPALVTATAGITPMLPGMAVFRAVFYFAVE
Mb3764|M.bovis_AF2122/97 WTAAIGVGFLATLISIRR-QAPALVTATAGIMPMLPGLAVFRAVFAFAVN
Rv3737|M.tuberculosis_H37Rv WTAAIGVGFLATLISIRR-QAPALVTATAGIMPMLPGLAVFRAVFAFAVN
MMAR_3034|M.marinum_M GIAAVGVGFLATLISIRR-QALALVTATAGIVPMLPGLAVFRAVFYFAAD
MUL_2274|M.ulcerans_Agy99 GIAAVGVGFLATLISIRR-QALALVTATAGIVPMLPGLAVFRAVFYFAAD
MAB_0256c|M.abscessus_ATCC_199 FVGAVAVVPFALFAARFKGAPSAIVLLLAAFWCLVPGALSFVNVSEVAAT
MAV_3251|M.avium_104 VQGASHLLFVPQLLLFMLSTGIAPEQTFPG---WLRPYVRNQPVSQFAET
.. : . : .. : . .
MSMEG_3837|M.smegmatis_MC2_155 DGDSAFPATVISMISVALGLQAGLVLWQLLRLRRSTAPQRAAR-------
TH_0574|M.thermoresistible__bu DGDSALGVTFISMISVALGLQAGLVLWQLLRRAR----RRAG--------
Mflv_0954|M.gilvum_PYR-GCK KDFAAGMTQAMVAAATALAIGAGVVMGELLGSPLRYRAGRIGQFLQVQGP
Mvan_5838|M.vanbaalenii_PYR-1 RDFAAGMAQALAAAATALAIGAGVVMGELAGSPLRYRAGRISDFLRVEGP
Mb3764|M.bovis_AF2122/97 DTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGP
Rv3737|M.tuberculosis_H37Rv DTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGP
MMAR_3034|M.marinum_M SHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGP
MUL_2274|M.ulcerans_Agy99 SHFDEAQSQLLSAAATALALGSGVVLGEFVGSPLRYRAGRIGHLLRIEGP
MAB_0256c|M.abscessus_ATCC_199 G--HANLTALLDTCMAIFSIALGLLVGASLHRGMRYALTVSR--------
MAV_3251|M.avium_104 LRGLARGHVIVGNVAATLAWCVGAVL---VFGAITLRMQRRG--------
: . :. * ::
MSMEG_3837|M.smegmatis_MC2_155 --------------------------------------------------
TH_0574|M.thermoresistible__bu --------------------------------------------------
Mflv_0954|M.gilvum_PYR-GCK PGLRRAVGRVVRLGPAEDQDATPASPYQRSWSVALEPLPAEPALEGSHTD
Mvan_5838|M.vanbaalenii_PYR-1 PGLRRAVGNVVALRPAADQQSS-RSPHQRSWSVALEPELSEVATEANGED
Mb3764|M.bovis_AF2122/97 PGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTTADDVDAGYRGD
Rv3737|M.tuberculosis_H37Rv PGLRRAVGRVVRLQPAKSQQPT-GTGGQRWRSVALEPTTADDVDAGYRGD
MMAR_3034|M.marinum_M PGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPASTDHSDAAEDND
MUL_2274|M.ulcerans_Agy99 PGLRRAVGRVVRLEPTKNAQST-NTRGQQSRSVALEPASTDHSDAAEDND
MAB_0256c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3251|M.avium_104 --------------------------------------------------
MSMEG_3837|M.smegmatis_MC2_155 ------------------
TH_0574|M.thermoresistible__bu ------------------
Mflv_0954|M.gilvum_PYR-GCK TPGTEDAPDAT-------
Mvan_5838|M.vanbaalenii_PYR-1 PAPERDATGER-------
Mb3764|M.bovis_AF2122/97 WPATCTSATEVR------
Rv3737|M.tuberculosis_H37Rv WPATCTSATEVR------
MMAR_3034|M.marinum_M RTGGHGGHGGHGGHRDES
MUL_2274|M.ulcerans_Agy99 RTGGHGGHGGHGGHRDES
MAB_0256c|M.abscessus_ATCC_199 ------------------
MAV_3251|M.avium_104 ------------------