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TAVVEVPQPDVEGISQPQAVVVGVMAGAGVQIGVLLDANAPVSVMTEPLLKVVNSRLRELGETPLEATGR GRWALCLVDGSPLRATQSLSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLSKRFAAIDPVVAVQ VGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIGVLMLGVSVLLLMRATTQQERRVGDTLLLSSLAP VSVAAAAAPPGGVGSPQAVLGFGVLTIAAVLALRFTGRRLAIYTAIVTVSAIAALAALARMVAMTGAVTL LTCVVLVSVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPTTVVRSDGGPPVLEGPASVRDVLT QAERARSFLSGLLIGLGVLMVVSLTALSDPRTGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGTAV LIVGAVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVYSPLFRKFVEWIEYLCLMPIFPLAL WLMNVYAAIRYR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2919 | snm | - | 100% (503) | secretion protein Snm4 |
| M. avium 104 | MAV_0157 | snm | 1e-39 | 26.46% (480) | secretion protein Snm4 |
| M. avium 104 | MAV_4863 | - | 1e-13 | 23.39% (449) | hypothetical protein MAV_4863 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1823 | - | 0.0 | 79.52% (503) | hypothetical protein Mb1823 |
| M. gilvum PYR-GCK | Mflv_0764 | - | 7e-21 | 24.65% (499) | hypothetical protein Mflv_0764 |
| M. tuberculosis H37Rv | Rv1795 | - | 0.0 | 79.32% (503) | hypothetical protein Rv1795 |
| M. leprae Br4923 | MLBr_01539 | - | 0.0 | 77.93% (503) | hypothetical protein MLBr_01539 |
| M. abscessus ATCC 19977 | MAB_3757 | - | 6e-27 | 25.65% (499) | hypothetical protein MAB_3757 |
| M. marinum M | MMAR_2677 | - | 0.0 | 78.13% (503) | hypothetical protein MMAR_2677 |
| M. smegmatis MC2 155 | MSMEG_0068 | - | 7e-20 | 21.88% (512) | transmembrane protein |
| M. thermoresistible (build 8) | TH_2236 | - | 6e-22 | 23.58% (509) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3080 | - | 0.0 | 77.93% (503) | hypothetical protein MUL_3080 |
| M. vanbaalenii PYR-1 | Mvan_0081 | - | 6e-24 | 24.39% (529) | hypothetical protein Mvan_0081 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1823|M.bovis_AF2122/97 MTAVADAP--------QADIEGVASPQAVVVGVMAGEGVQIGVLLDANAP
Rv1795|M.tuberculosis_H37Rv MTAVADAP--------QADIEGVASPQAVVVGVMAGEGVQIGVLLDANAP
MMAR_2677|M.marinum_M MTAVADAP--------QAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAP
MUL_3080|M.ulcerans_Agy99 MTAVADAP--------QAELEGVSSPRAVVVGIMAGEGVQIGVLLDANAP
MAV_2919|M.avium_104 MTAVVEVP--------QPDVEGISQPQAVVVGVMAGAGVQIGVLLDANAP
MLBr_01539|M.leprae_Br4923 MTAVADAP--------RTDIEGTSSPRVVVVGIVAGEGAQISVLLDANAP
Mflv_0764|M.gilvum_PYR-GCK ------------------------------MTILTGR-RMTDLVLPSAAP
Mvan_0081|M.vanbaalenii_PYR-1 MTATVAP------PTSSN--VTPGRPTTTRVTILTGR-RMTDLVLPSAAP
MSMEG_0068|M.smegmatis_MC2_155 MTSTAAA-----ADTSS---VTPGRPSTTRVTILTGK-RMTDLVLPATAP
TH_2236|M.thermoresistible__bu LTATASASAPGAAATASGTGATPARPATTRVTILTGR-RMTDLVLPAAAP
MAB_3757|M.abscessus_ATCC_1997 MTHAQSGAE-----------QRSAVLELCRVSIQAER-TQVDLALPTSVP
: : : .: * : .*
Mb1823|M.bovis_AF2122/97 VSVMTDPLLKVVNSRLRELG---EAPLEATGRGRWALCLVDGAPLRATQS
Rv1795|M.tuberculosis_H37Rv VSVMTDPLLKVVNSRLRELG---EAPLEATGRGRWALCLVDGAPLRATQS
MMAR_2677|M.marinum_M VSVMTDPLLKVVNSRLRELG---ESTLEAAGRGRWALCLIDGSPLRATQS
MUL_3080|M.ulcerans_Agy99 VSVMTDPLLKVVNSRLRELG---ESTLEAAGRGRWALCLIDGSPLRATQS
MAV_2919|M.avium_104 VSVMTEPLLKVVNSRLRELG---ETPLEATGRGRWALCLVDGSPLRATQS
MLBr_01539|M.leprae_Br4923 VSVMTDPLLKVINSRLCELG---EGTLEPTGRGRWALCLIDGTPLWPTQS
Mflv_0764|M.gilvum_PYR-GCK IETYVDETVAVLGDILSDTPPDVLAGFDFTAQGVWSFARPGAPPIKLTDS
Mvan_0081|M.vanbaalenii_PYR-1 IETYVDETVSVLADILADTPENVLADFDFKAQGVWSFARPGAPPIKLTES
MSMEG_0068|M.smegmatis_MC2_155 IETYIDETVSFLAELLEDAPKDVLAGFNFGEQGVWAFARPGAPPLKADES
TH_2236|M.thermoresistible__bu IESYIDETVSVLAELLEDTPSDVLAGFDFKAQGVWAFARPGAPPLKSDES
MAB_3757|M.abscessus_ATCC_1997 LALLVGSIVDIINQHVGVPE---LTSPEDAVETHWRLSRPGQPPLQMSST
: : .: . : : . * :. . .*: .:
Mb1823|M.bovis_AF2122/97 LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVA
Rv1795|M.tuberculosis_H37Rv LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVASDLSKRFARIDPIVA
MMAR_2677|M.marinum_M LTEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVASNLSKRFASIDPVVA
MUL_3080|M.ulcerans_Agy99 LTEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVASNLSKRFASIDPVVA
MAV_2919|M.avium_104 LSEQDVYDGDRLWIRFIPDTEHRSQVIEHISTAVAANLSKRFAAIDPVVA
MLBr_01539|M.leprae_Br4923 LTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVSANLSKRFAAIDSIVA
Mflv_0764|M.gilvum_PYR-GCK LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAV-LDETPEFDRRALY
Mvan_0081|M.vanbaalenii_PYR-1 LDDAGVVDGSLLTVVSVSRTERYRPLVEDVIDAIAV-LDETPEFDRSALY
MSMEG_0068|M.smegmatis_MC2_155 LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAV-LDESPVFDRTALK
TH_2236|M.thermoresistible__bu LDDAGVVDGSLLTLVSVSRTERYRPLVEDVIDAIAV-LDESPEFDRSALN
MAB_3757|M.abscessus_ATCC_1997 LGELEVRDGD-LLILTRSDVAAPDPLFDDVFLAVSTFRTVSAHPWSRNAA
* : * **. * : . . :.:.: *::
Mb1823|M.bovis_AF2122/97 VQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVLVLAVAMLLL
Rv1795|M.tuberculosis_H37Rv VQVGASMVATGVVLATGVLGWWRWHHNTWLTTIYTAVIGVLVLAVAMLLL
MMAR_2677|M.marinum_M VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MUL_3080|M.ulcerans_Agy99 VQVGAGMVGTGVILASGVLGWWRWHHNTWLTTIFASVIAVLVLMVAMMLL
MAV_2919|M.avium_104 VQVGATMVAVGVTAASGLLGWWRWHHNSWLPTVYAGVIGVLMLGVSVLLL
MLBr_01539|M.leprae_Br4923 VQVGALMVATGVLASSVLLVWWRWHHGFWLSVIYATVIALLILVMSTLVL
Mflv_0764|M.gilvum_PYR-GCK RFVGLVLPLVALLTTVMAVLSWSSTGRDWWWAAALGVLGTGLLGGSALSQ
Mvan_0081|M.vanbaalenii_PYR-1 RFVGLILPLAAFMVACVAILSWSSTGRDWWWAVALGVLGAGLMGGSVLAQ
MSMEG_0068|M.smegmatis_MC2_155 HFVAIALPIVATIITVATLIAWTRSGHGWWWAVALGVLGLGLLGGSMAAK
TH_2236|M.thermoresistible__bu RYIAVAIPIVSLIVTIVGLLSWANSGQSWWWALGLGLLGLGVLGGSMLAK
MAB_3757|M.abscessus_ATCC_1997 RILGASVCGLSALLGATALLRAGATNPGLLLPIIAVAIALVAMTAAVFAN
:. : . : :. : :
Mb1823|M.bovis_AF2122/97 MRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGS-PQAVLGFGVLTV
Rv1795|M.tuberculosis_H37Rv MRAKTDADRRVADIMLMSAIMPVTVAAAAAPPGPVGS-PQAVLGFGVLTV
MMAR_2677|M.marinum_M MRATTDADRRVADIMLVSGLAPLTVAAASAPPGSVGS-PQAVLGFGVLSI
MUL_3080|M.ulcerans_Agy99 MRATTDADRRVADIMLVSGLAPLTVAAASAPPGSVGS-PQAALGFGVLSI
MAV_2919|M.avium_104 MRATTQQERRVGDTLLLSSLAPVSVAAAAAPPGGVGS-PQAVLGFGVLTI
MLBr_01539|M.leprae_Br4923 MRATTREDRRAGDIMLLSGIAPVTAAAAAAPPGPLGS-PHAVMGFGVFAI
Mflv_0764|M.gilvum_PYR-GCK RRYGNFDMAESLLVSALVTLTGAVVLAVPLPDGVESLGAPQVAGAGALIL
Mvan_0081|M.vanbaalenii_PYR-1 NRYRHLDMAESLLVSSLVTLVGAVVLAVPLPEGVDSLGAPQVAGAGALVL
MSMEG_0068|M.smegmatis_MC2_155 SRYNSLDMSESLLLAATPALAGAVGLAVPLPRGVDGLGAPQLAGAAAVVL
TH_2236|M.thermoresistible__bu SRYDNIDMTESLLVGSMPLLAGAAALAVPLPRGVTSLGAPQLAAVGAVIL
MAB_3757|M.abscessus_ATCC_1997 ---RVYDDSLASVMLSHCAVGFSAVAGALFVPGKYGA-PHAMLALMVAMV
: .. * . . . . :
Mb1823|M.bovis_AF2122/97 AAALALRFTGRRLGIYTAIVIIDALTMLAALARMVAATSAVTLLSSLLLI
Rv1795|M.tuberculosis_H37Rv AAALALRFTGRRLGIYTTIVIIGALTMLAALARMVAATSAVTLLSSLLLI
MMAR_2677|M.marinum_M AAALALRFTGRRLAIYTAIVTICGLTTLASLSRMVAATSAVTLFATMLLI
MUL_3080|M.ulcerans_Agy99 AAALALRFTGRRLAIYTAIVTICGLTTLASLSRMVAATSAVTLFATMLLI
MAV_2919|M.avium_104 AAVLALRFTGRRLAIYTAIVTVSAIAALAALARMVAMTGAVTLLTCVVLV
MLBr_01539|M.leprae_Br4923 AAMLALRFTGRQLSIYTAMITISVVVAIASLARMVAMTSAVTLLSCVMLA
Mflv_0764|M.gilvum_PYR-GCK LMVLATRGGPHRRAEVAAFLAVVALALTFAAVAYGYGWNAWVPAGAIAFG
Mvan_0081|M.vanbaalenii_PYR-1 LMVLATRGGPRRRAEVAAFLAVIALALTIAAVAFGYGWNDWVPAGAIAFG
MSMEG_0068|M.smegmatis_MC2_155 LLTLATRGGPRKRAEVASFVAVTSIAVTAAAIAFGYGWQEWVPAGAIAFG
TH_2236|M.thermoresistible__bu LITLASRGGPRRRAELASFIAVTALAVTAAAVAYGYGWEYWVPVGAIAFG
MAB_3757|M.abscessus_ATCC_1997 VSILAMRATGTGTTSLVAVASASFLGFAAALGYVLFEPPIYSLGAVLGSV
** * .:. : : :
Mb1823|M.bovis_AF2122/97 CVVAYHAAPALSRRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAP
Rv1795|M.tuberculosis_H37Rv CVVAYHAAPALSRRLAGIRLPVFPSATSRWVFEARPDLPTTVVVSGGSAP
MMAR_2677|M.marinum_M CVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAVAAGGPP
MUL_3080|M.ulcerans_Agy99 CVVMYHASPALSRRLSGIRLPVFPSATSRWVFEARPDLPTTVAVAAGGPP
MAV_2919|M.avium_104 SVLIYQSAPAISRRLAGIRLPVFPSATSRWVFEARPDLPTTVVRSDGGPP
MLBr_01539|M.leprae_Br4923 CVLLYHCAPALSRRLAGIRLPVFPSATSRWVFEARPDLPNTVVRSDGGPP
Mflv_0764|M.gilvum_PYR-GCK LIVVTNAA-KMTVAVARIALPPIPAPGESVTNDELLDPVATTDAS-EESE
Mvan_0081|M.vanbaalenii_PYR-1 LIVVTNAA-KLTVAVARIALPPIPAPGETVTNDELLDPVTTTDAS-EESE
MSMEG_0068|M.smegmatis_MC2_155 LIVVTNAA-KLTVAVARIALPPIPAPGEHVSNDELLDPVVTPDSIDDASP
TH_2236|M.thermoresistible__bu LIVVTNAA-KLTVAVARIALPPIPAPGETVTNDDLLDPVITPDGSDEETS
MAB_3757|M.abscessus_ATCC_1997 GICAVALSPRVAMVLARLPLPPVPTQGAPSRPEHSTAPIEAIEGLDGLDT
: : :: :: : ** .*: : :
Mb1823|M.bovis_AF2122/97 ------VLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCD--
Rv1795|M.tuberculosis_H37Rv ------VLEGPSSVRDVLLQAERARSFLSGLLTGLGVMVVVCMTSLCD--
MMAR_2677|M.marinum_M ------VLEGPASVRDVVLQAERARSFLSGLLVGLGVLMVVSLTSLCN--
MUL_3080|M.ulcerans_Agy99 ------VLEGPASVRDVVLQAERARSFLSGLLVGLGVLMVVSLTSLCN--
MAV_2919|M.avium_104 ------VLEGPASVRDVLTQAERARSFLSGLLIGLGVLMVVSLTALSD--
MLBr_01539|M.leprae_Br4923 ------VLEGPASVRDVLLQSERARSYLSGLLLGLGVLLVVSLTALSN--
Mflv_0764|M.gilvum_PYR-GCK TWQ-AIIASVPDSAARLTERSRLAKRLLIGFLS-AGALILVLGSVFVV--
Mvan_0081|M.vanbaalenii_PYR-1 TWQ-AIIASVPSSAARLTERSRLAKRLLIGFLS-AGALILAAGSIAVV--
MSMEG_0068|M.smegmatis_MC2_155 TWQ-AIIASVPESAARLQERSQLTRQLLIGFLS-AGALILTVGAIAVV--
TH_2236|M.thermoresistible__bu TWQ-AIIASVPESAQRLQERSTLAKQLLIGFLT-AGAVVLSAGAIAVV--
MAB_3757|M.abscessus_ATCC_1997 EGDDVEDATALPPLPDLREKALRAHAVLTGLVCGTSAVTAVGAMLAALTF
. : :: :: * *:: ..:
Mb1823|M.bovis_AF2122/97 -------PHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTAVII
Rv1795|M.tuberculosis_H37Rv -------PHTGQRWLPLILAGFTSGFLLLRGRSYVDRWQSITLAGTAVII
MMAR_2677|M.marinum_M -------PHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIV
MUL_3080|M.ulcerans_Agy99 -------PHTSERWLPLMLAGFTSGFLMLRGRSYVDRWQSITLAVTAVIV
MAV_2919|M.avium_104 -------PRTGQRWLPVLLAGFCAGFLLLRGRSYVDRWQAITLAGTAVLI
MLBr_01539|M.leprae_Br4923 -------PHVGQRWLPLLLAGFTSGFLLLRGRSYVDRWQAITLAATAVLI
Mflv_0764|M.gilvum_PYR-GCK -------VQGHFFVHSMIVAGLVTMLAGFRSRLYVERWCAWALMAAAVAI
Mvan_0081|M.vanbaalenii_PYR-1 -------VQGHFFLHSMIVAGLVTMLCGFRSRLYAERWCAWALMAAAVAV
MSMEG_0068|M.smegmatis_MC2_155 -------VQGHFFVHSMIVASLVTVICGFRSRLYAERWCAWALLAATVAV
TH_2236|M.thermoresistible__bu -------VQGHFFVHSLIVAGLVTMICAFRSRLYAERWCAWALLAACTAI
MAB_3757|M.abscessus_ATCC_1997 SGAGGHHPTGAHRLSGVVLAGLIALAMMLRARSHADLAQTVAINLGGIAI
:::*.: : :*.* :.: : :: :
Mb1823|M.bovis_AF2122/97 AAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRK
Rv1795|M.tuberculosis_H37Rv AAAVCVRYALELSSPLAVSIVAAILVLLPAAGMAAAAHVPHTIYSPLFRK
MMAR_2677|M.marinum_M VAAVSVRYALVLSSPLSVSIVASLLVLLPAAGMTAAAVVPNTIYSPLFRK
MUL_3080|M.ulcerans_Agy99 VAAVSVRYALVLSSPLSVSIVASLLVLLPAAGMTAAAVVPNTIYSPLFRK
MAV_2919|M.avium_104 VGAVVVRYALVLQSPLAVSISAAILVLVPVAGLTSAAVVPNTVYSPLFRK
MLBr_01539|M.leprae_Br4923 VAAVVVRYALVLSSPLAVSIGAAILVLLPAAGLIAAAVVPNTIYSPLFRK
Mflv_0764|M.gilvum_PYR-GCK PSGIAVRMSLWYP-DRAWWVLGIYTVAAAVALIVVGATDGVRRISPVTKR
Mvan_0081|M.vanbaalenii_PYR-1 PTGVVVRLCLWYP-ERAWLLLAIYTALALLAVIVIGASEGVRRISPVTKR
MSMEG_0068|M.smegmatis_MC2_155 PTGLMIKLSMWWP-DSAWIVMGIYTMLALIALIVVGATDGVRRVSPVTKR
TH_2236|M.thermoresistible__bu PTGVMVKLCMWYP-ERAAVVLGIYVAAVLVAVIAVGATHGVRRMSPVTKR
MAB_3757|M.abscessus_ATCC_1997 PAAAFAFVAVAYP--TAAVFTTVLAAIAAGSAIALGFLVSARKYSPVARR
. .: : . : : . **: ::
Mb1823|M.bovis_AF2122/97 FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
Rv1795|M.tuberculosis_H37Rv FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
MMAR_2677|M.marinum_M FVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MUL_3080|M.ulcerans_Agy99 FVEWTEYLCLMPIFPLAFWLMNVYAAIRYR---
MAV_2919|M.avium_104 FVEWIEYLCLMPIFPLALWLMNVYAAIRYR---
MLBr_01539|M.leprae_Br4923 LVEWIEYLCLVPIFPLALWLMDVYTAIRYR---
Mflv_0764|M.gilvum_PYR-GCK ILELLDGATIAAVIPLLLWISGVYDVLRNLRF-
Mvan_0081|M.vanbaalenii_PYR-1 ILELLDGATIAAVIPMLLWIAGVYDVLRNLRF-
MSMEG_0068|M.smegmatis_MC2_155 ILELFDGAAIAAVIPLLLWIAGVYDLLRNLRLH
TH_2236|M.thermoresistible__bu ILELVDGAAIAATIPMLLWIGSVFDILRNIRF-
MAB_3757|M.abscessus_ATCC_1997 TVEIIEYIALSLIVPIAVWVCGVYSAVRGLNLP
:* : : .*: .*: .*: :*