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LRPGPDGGFAPYPPPQAYPVHPGYASAPGFGAPVPGIVALRPLSLSDIFNGAVAYIRRNPKATLGLTTIV VVLAQLVTLLLQVGPLAAMGGLGSEVQGEAPSTGAVAMFSGATLAGVLVTQLASVLLTGMLTVIIGRSIF GGTVTIGQAWERLRGRLLALIGLTLLEAVVLLAVVLVVIGLIAAAGAVGGAVAAFVMGVPLVLAAVLGAL FGLTVLLFAPVLIVLERLDVFAAIARSFALVKTGFWRVLGIWLLASLVASVIASAVGAPFSIVGQLLTMS PDGVGMSIVGLVLVAVGGTIGQIVTAPFAAGVDVLLYTDRRIRAEAFDLVLRTGAYTPAPPAAPAESTDQ LWLVRHF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6216 | - | - | 100% (357) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 2e-08 | 22.97% (296) | hypothetical protein MSMEG_5268 |
| M. smegmatis MC2 155 | MSMEG_3459 | - | 4e-05 | 28.63% (248) | hypothetical protein MSMEG_3459 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3714 | - | 2e-95 | 53.02% (381) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1340 | - | 4e-97 | 51.64% (366) | putative transmembrane protein |
| M. tuberculosis H37Rv | Rv3689 | - | 1e-95 | 54.45% (371) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0392c | - | 1e-67 | 42.42% (363) | hypothetical protein MAB_0392c |
| M. marinum M | MMAR_5199 | - | 7e-96 | 54.55% (363) | hypothetical protein MMAR_5199 |
| M. avium 104 | MAV_0415 | - | 3e-95 | 53.37% (356) | hypothetical protein MAV_0415 |
| M. thermoresistible (build 8) | TH_3239 | - | 3e-92 | 57.63% (321) | PUTATIVE putative putative conserved transmembrane protein |
| M. ulcerans Agy99 | MUL_4272 | - | 9e-97 | 54.50% (367) | hypothetical protein MUL_4272 |
| M. vanbaalenii PYR-1 | Mvan_5452 | - | 3e-97 | 52.30% (369) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1340|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5452|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3714|M.bovis_AF2122/97 MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
Rv3689|M.tuberculosis_H37Rv MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
MMAR_5199|M.marinum_M --------------------------------------MSTLPPPGYPVE
MUL_4272|M.ulcerans_Agy99 --------------------------------------MSTLPPPGYPVE
MAV_0415|M.avium_104 -------------------MCATLRAG----ARVNVVKWSGRRQDGAHDE
MSMEG_6216|M.smegmatis_MC2_155 -----------------------------------------MRP------
TH_3239|M.thermoresistible__bu --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK MTYDAGGYGPAGFPP-------PRYP-------------PPPGYGPPPG-
Mvan_5452|M.vanbaalenii_PYR-1 MTYNAGGYGPAGPPP-------PGYPAPGY------PGYPPAGYGAPPQY
Mb3714|M.bovis_AF2122/97 PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
Rv3689|M.tuberculosis_H37Rv PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
MMAR_5199|M.marinum_M PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPPPG
MUL_4272|M.ulcerans_Agy99 PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPP-G
MAV_0415|M.avium_104 PPVHEPRGSVSAPPPGYPVGPPPAYGSQSHYG--TQYGAQYPGQYGVH--
MSMEG_6216|M.smegmatis_MC2_155 ----GPDGGFAPYPP------PQAYPVH----------------------
TH_3239|M.thermoresistible__bu --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199 MSNDEGGVTPSPLPP----GPSPAYPPP-------APGYPPAGTAGYP--
Mflv_1340|M.gilvum_PYR-GCK WQPP----GYGAPGYPPPYGGP------------PVLKPGVVPLRPLTLS
Mvan_5452|M.vanbaalenii_PYR-1 WQPPGYAPGYGAPGYPPQFGLP------------PVIKPGVVPLRPLTLS
Mb3714|M.bovis_AF2122/97 YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPLAPGAVKPGIIPLRPLTLS
Rv3689|M.tuberculosis_H37Rv YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPVAPGAVKPGIIPLRPLTLS
MMAR_5199|M.marinum_M YGPPP-GYGPPPPGYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MUL_4272|M.ulcerans_Agy99 YAPPPPGYGPPP-GYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MAV_0415|M.avium_104 YGPPP---TYPPPGYPPAPAFG-PPPGYG------VLKPGIIPLRPLTLG
MSMEG_6216|M.smegmatis_MC2_155 ------------PGYASAPGFG-------------APVPGIVALRPLSLS
TH_3239|M.thermoresistible__bu --------------VNPMAPMR-----------QTALKPGVIPLRPLTLS
MAB_0392c|M.abscessus_ATCC_199 --PPGFAYQPPPPGYQNPSAVP-----YWVTPEPPALKPGVIPLRPLDLS
. **::.**** *.
Mflv_1340|M.gilvum_PYR-GCK DIFNGAVAYVRANPKATLGLTTIVVVAAQILSLVLSLVPFTF--TDMVAD
Mvan_5452|M.vanbaalenii_PYR-1 DIFNGAVAYIRTNPKATLGLTAIVVIASQIVALLLSLWPFAF--TGQVAS
Mb3714|M.bovis_AF2122/97 DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVT
Rv3689|M.tuberculosis_H37Rv DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVT
MMAR_5199|M.marinum_M DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLATIGPLEA--ASRFDT
MUL_4272|M.ulcerans_Agy99 DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLAAIGPLEA--ASRFDT
MAV_0415|M.avium_104 DIFNGAVGYIRANPKATLGLTAIVVIAMQIITKAAVLGPLAA--YGRFTG
MSMEG_6216|M.smegmatis_MC2_155 DIFNGAVAYIRRNPKATLGLTTIVVVLAQLVTLLLQVGPLAA--MGGLGS
TH_3239|M.thermoresistible__bu DIFNGAVAYIRTNPKATLGLTAIVVVVAQLLALVLQIGSLAA--TGDLVS
MAB_0392c|M.abscessus_ATCC_199 SLYNGAIAAIRANPKTTLGLTAIVVIVSQLLIFGIQAAPATAVLTGAASF
.::***:. :* ***:*****::**: *:: . .
Mflv_1340|M.gilvum_PYR-GCK GLGEDEASVQVIVG-WVASSLAGGIATALAATVLAGMLTVVIGRSVFGAG
Mvan_5452|M.vanbaalenii_PYR-1 TLDGDEASTEVLVS-WMASSLATAITTGLSTTLLSGLLTVVIGRSVFGAD
Mb3714|M.bovis_AF2122/97 GEPDELT-GAVVGG-WSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
Rv3689|M.tuberculosis_H37Rv GEPDELT-GAVVGG-WSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
MMAR_5199|M.marinum_M -HPSELS-WGVVGA-WTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MUL_4272|M.ulcerans_Agy99 -HPSELS-WGVVGA-WTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MAV_0415|M.avium_104 DRSDELT-AGVLGA-WSVSVGAGVLVGWLGGMLLSGMLTVIVGRAVFGSS
MSMEG_6216|M.smegmatis_MC2_155 EVQGEAPSTGAVAM-FSGATLAGVLVTQLASVLLTGMLTVIIGRSIFGGT
TH_3239|M.thermoresistible__bu SVRGDDVSTVGLSW-ADLASVTTAVANTLALLVLSGMLTVVIGRAVFGAG
MAB_0392c|M.abscessus_ATCC_199 DKNTEDSFGAAFGLGYIGGQLIGAVVTSLVTIILSGMLTVTIGRSVFGER
: . . :. * :*:*:*** :**::**
Mflv_1340|M.gilvum_PYR-GCK ITVGEAWKRLRPRFWPLIGFTVLKMLVFLVGLVLVVGIIGATGALTTGVV
Mvan_5452|M.vanbaalenii_PYR-1 ITIGEAWRRLRPRLWALIGFTVLKTLALIVWFGVVLLIVVLAVAVIDGPA
Mb3714|M.bovis_AF2122/97 ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
Rv3689|M.tuberculosis_H37Rv ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
MMAR_5199|M.marinum_M ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MUL_4272|M.ulcerans_Agy99 ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MAV_0415|M.avium_104 ITVGETWTKIRGRLPALLGLALLEAVVVAAIAGLVVVVIAILAAIGNAAA
MSMEG_6216|M.smegmatis_MC2_155 VTIGQAWERLRGRLLALIGLTLLEAVVLLAVVLVVIGLIAAAGAVGGAVA
TH_3239|M.thermoresistible__bu ITISEAWERLRGRLWALIGFSVLELLAVVVIVVLAVVMGAALAAAGGAGA
MAB_0392c|M.abscessus_ATCC_199 TTIKEAWQRAKPRIWALLGVAVVELVLFAVVLGFGVAVVVGLALTVGPAG
*: ::* : : *: .*:*.:::: . . . : :
Mflv_1340|M.gilvum_PYR-GCK AFAVAIPLVLAAVLAAVWLSVMLTFAPVIIVLERRDIVTAVKRSFTLIKA
Mvan_5452|M.vanbaalenii_PYR-1 AFLIAAPLVLASILAAVWVSVMLTFAPAVIVLERRDIVTSVKRSFALIKS
Mb3714|M.bovis_AF2122/97 AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
Rv3689|M.tuberculosis_H37Rv AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
MMAR_5199|M.marinum_M AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MUL_4272|M.ulcerans_Agy99 AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MAV_0415|M.avium_104 AVVLGIPLVLTVIAVLVYLYTVVLFAPVLIVLERLPVLDAITRSFRLVRR
MSMEG_6216|M.smegmatis_MC2_155 AFVMGVPLVLAAVLGALFGLTVLLFAPVLIVLERLDVFAAIARSFALVKT
TH_3239|M.thermoresistible__bu GALI-VLLFLGTVALLAYLATVLSFGPPVIVLERLGVFAAIARSFGLVRN
MAB_0392c|M.abscessus_ATCC_199 AIPAGLLLALAYFLFYLYLIPVFSLVPSVLILEQQSVFGAIGRSVSLVRK
. * * : :. : * :::**: :. :: **. *:
Mflv_1340|M.gilvum_PYR-GCK DFWRVFGIWLLAAIVAQFIAGAVSIPFTLGGQIAFSA-SAT---TASAML
Mvan_5452|M.vanbaalenii_PYR-1 DFWRVFGIWLLAAIVAQFIAGAVSIPFSIGGQAVLTA-SAT---TTAAMI
Mb3714|M.bovis_AF2122/97 GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
Rv3689|M.tuberculosis_H37Rv GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
MMAR_5199|M.marinum_M GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MUL_4272|M.ulcerans_Agy99 GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MAV_0415|M.avium_104 GFWRVLGIRALAFLVTAVVANAVAVPFSIVGQVFQIS-SSG----TAFLI
MSMEG_6216|M.smegmatis_MC2_155 GFWRVLGIWLLASLVASVIASAVGAPFSIVGQLLTMS-PDG---VGMSIV
TH_3239|M.thermoresistible__bu SFWRVFGIRLLAWLVAGVISVAVAVPFSVAGGLFGLS-ADS---SALAII
MAB_0392c|M.abscessus_ATCC_199 GFWRLLGILVLTGFIVGFVSMIIGMPFILVGEVAAFAGSDPNNLGPKMLL
.***::** *: ::. .:. :. ** : * . ::
Mflv_1340|M.gilvum_PYR-GCK AFALFAIGGAIGQIITGPFTAGVSVLQYADRRIRAEAFDLVLQTG---AT
Mvan_5452|M.vanbaalenii_PYR-1 SMVLFSVGGAVGQIITGPFSAGVTVLQYTDRRIRAEAFDLVLQTG---AA
Mb3714|M.bovis_AF2122/97 GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
Rv3689|M.tuberculosis_H37Rv GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
MMAR_5199|M.marinum_M GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MUL_4272|M.ulcerans_Agy99 GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MAV_0415|M.avium_104 STAILSVGAAIGEIITAPFNAGVIVLLYTDRRMRAEAFDLLQS-----GA
MSMEG_6216|M.smegmatis_MC2_155 GLVLVAVGGTIGQIVTAPFAAGVDVLLYTDRRIRAEAFDLVLRTG-AYTP
TH_3239|M.thermoresistible__bu SLTLIAIGGAVGQIITTPFNAGVIVLLYADRRIRAEAFDLVLQT----GA
MAB_0392c|M.abscessus_ATCC_199 IFALAAVGAVIAQIISLPFKAAVNVLLYTDQRMRTEALDLVLQTEAR-TR
.: ::* .:.:*:: ** *.* ** *:*:*:*:**:**:
Mflv_1340|M.gilvum_PYR-GCK AGPYAPADSTDDLWLTR-----------
Mvan_5452|M.vanbaalenii_PYR-1 AGPQAPADSTDDLWLTGPR---------
Mb3714|M.bovis_AF2122/97 AGGPAPVESTDNLWLTRPF---------
Rv3689|M.tuberculosis_H37Rv AGGPAPVESTDNLWLTRPF---------
MMAR_5199|M.marinum_M AGGPAAVESTDNLWLTRPL---------
MUL_4272|M.ulcerans_Agy99 AGGPAAVESTDTLWLTRPL---------
MAV_0415|M.avium_104 AQGSYAAASTDNLWLTRPR---------
MSMEG_6216|M.smegmatis_MC2_155 APPAAPAESTDQLWLVRHF---------
TH_3239|M.thermoresistible__bu TAGPAHAESTDQLWLPRPTTPWAAHHPR
MAB_0392c|M.abscessus_ATCC_199 ERLGQPGIDPDSLWLPMRPPVQV-----
..* ***