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MTEPSHALRLLLGTRPPRADAERNLNSLLAATKQIVLDGELNPSAAQIADAAGVGVGTLYRRTLGKETLL AAAVIDLLDEVCERATLAATGESWSAFEQFALDYLRIRKITCSITHALEDEFDGGVADAKKRTRKAFEVL TRRLHESGIVDPDVDAADLMVLLASIDVTEDTLGLSPNPKRRQRVVQRMLAGIRTGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3406 | - | - | 100% (197) | putative transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1380 | - | 9e-13 | 33.12% (160) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 1e-10 | 30.81% (185) | TetR-type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 2e-07 | 26.49% (185) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 4e-09 | 30.43% (161) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 2e-07 | 26.49% (185) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 4e-06 | 37.68% (69) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4384 | - | 3e-13 | 31.08% (148) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2984 | - | 2e-06 | 40.35% (57) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4593 | - | 8e-07 | 27.07% (181) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4015 | - | 3e-05 | 25.33% (150) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1059 | - | 3e-12 | 28.33% (180) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 ------------------------MAPTDRRVRADAARNRARVLEVAYQT
Rv0067c|M.tuberculosis_H37Rv ------------------------MAPTDRRVRADAARNRARVLEVAYQT
MLBr_00316|M.leprae_Br4923 -------------MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEA
Mflv_0142|M.gilvum_PYR-GCK ---------------------------MTRPLRADAARNRARVLEVAYDT
MAB_4384|M.abscessus_ATCC_1997 ---------------------MNGREVAHRPLRKDAERNRKRVIAAAREL
Mvan_1059|M.vanbaalenii_PYR-1 ---------------------MIDK--PCRGLRKDAERNRQRVLTAAREL
MAV_4593|M.avium_104 -----------------------------MVGRSDARRNRQRLLEAATAA
MSMEG_3406|M.smegmatis_MC2_155 ---------------MTEPSHALRLLLGTRPPRADAERNLNSLLAATKQI
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
MMAR_2984|M.marinum_M -----------------MTTSDRGAPAQANRSERRKRRTRTALLRAAQRL
*. :: .:
Mb0068c|M.bovis_AF2122/97 FAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDK
Rv0067c|M.tuberculosis_H37Rv FAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDK
MLBr_00316|M.leprae_Br4923 FATEGLSVP-IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDD
Mflv_0142|M.gilvum_PYR-GCK FAAEGLTVP-IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAER
MAB_4384|M.abscessus_ATCC_1997 FAVHGLEST-LNEVAHHAGLGVGTVYRRFPTKEALFEAIYVDGMDQLSGL
Mvan_1059|M.vanbaalenii_PYR-1 FAVEGMEAS-LNDVARHAGVGVGTVYRRFATKEELVEAIFESGVDEVVCL
MAV_4593|M.avium_104 FTAHGASVS-LESIARDAGVGIGTLYRHFPNREALVEAVYRAELAEVAAA
MSMEG_3406|M.smegmatis_MC2_155 VLDGELNPS-AAQIADAAGVGVGTLYRRTLGKETLLAAAVIDLLDEVCER
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
MMAR_2984|M.marinum_M IAEGKLNVP-VLEITQAADVGMGSFYNHFDSKEQLFEAAVADVLDAHGAL
. . .:: *. . *:.*. :* : :
Mb0068c|M.bovis_AF2122/97 G--HALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG--IEISSA
Rv0067c|M.tuberculosis_H37Rv G--HALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG--IEISSA
MLBr_00316|M.leprae_Br4923 G--YVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGG-IDILGV
Mflv_0142|M.gilvum_PYR-GCK A--RTLLAVEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG--LDLEAV
MAB_4384|M.abscessus_ATCC_1997 A--EAALRHENSWEG-FEWFVHQMCEITATNRGLREIAFSKA---HGGDH
Mvan_1059|M.vanbaalenii_PYR-1 A--EAALRHQDSWEG-FVWFVERQCLLTATDRGLREMVYSKA---YGGNR
MAV_4593|M.avium_104 A--AQLLQR-HPPKAALRRWMDRYATFVATKRGMAESLQAIF--ESGALV
MSMEG_3406|M.smegmatis_MC2_155 ----ATLAATGESWSAFEQFALDYLRIRKITCSITHALEDEF-----DGG
TH_4015|M.thermoresistible__bu VRTDAGTEPKNPYERILRANRTYLEAYRANRAIMIVWEQVASLNEHVEQL
MMAR_2984|M.marinum_M LD-RCTASIEDPAETFAASFRLTGRLFRRRPQESEILLANGAALLSSDRG
Mb0068c|M.bovis_AF2122/97 APEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN--
Rv0067c|M.tuberculosis_H37Rv APEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN--
MLBr_00316|M.leprae_Br4923 APDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN--
Mflv_0142|M.gilvum_PYR-GCK APGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFD--
MAB_4384|M.abscessus_ATCC_1997 VEAGRARLLPLLSKVVERAQEDGYLRPEASATDMPFFGVLTGAVSEFAGE
Mvan_1059|M.vanbaalenii_PYR-1 VERVRERLAPLMKELVERARRDGYLRPDVESTDMPVIGLLAGTVGEWAGD
MAV_4593|M.avium_104 PSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIGIFLVSGSP--
MSMEG_3406|M.smegmatis_MC2_155 VADAKKRTRKAFEVLTRRLHESGIVDPDVDAADLMVLLASIDVTEDTLGL
TH_4015|M.thermoresistible__bu RREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGMLSNFAYRWS
MMAR_2984|M.marinum_M LAPRALRDIKAASDAGRFRVEDPELALAMAGGALLGLGTLLRADPQRDGC
Mb0068c|M.bovis_AF2122/97 ---AELAAKVTDVALDGLRANRK---------------------------
Rv0067c|M.tuberculosis_H37Rv ---AELAAKVTDVALDGLRANRK---------------------------
MLBr_00316|M.leprae_Br4923 ---SALAERVTDVVVDGLRAAR----------------------------
Mflv_0142|M.gilvum_PYR-GCK ---SEVTERVTRVIEDGLRPLR----------------------------
MAB_4384|M.abscessus_ATCC_1997 V-NADLWRRYMAILIEGMRRRDDQERLEVDALDEAQIDAAMTTWQPAGSG
Mvan_1059|M.vanbaalenii_PYR-1 V-DPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAMHGWDPSG--
MAV_4593|M.avium_104 ----EQTGRMLDLLVAGVTR------------------------------
MSMEG_3406|M.smegmatis_MC2_155 SPNPKRRQRVVQRMLAGIRTGH----------------------------
TH_4015|M.thermoresistible__bu VQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA--------------
MMAR_2984|M.marinum_M AAADAVTEDLLRLFGLDAEQARAICRRPLPDLDGWDQPDSAA--------