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VIDKPCRGLRKDAERNRQRVLTAARELFAVEGMEASLNDVARHAGVGVGTVYRRFATKEELVEAIFESGV DEVVCLAEAALRHQDSWEGFVWFVERQCLLTATDRGLREMVYSKAYGGNRVERVRERLAPLMKELVERAR RDGYLRPDVESTDMPVIGLLAGTVGEWAGDVDPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAM HGWDPSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1059 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1060 | - | 2e-72 | 58.60% (215) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 6e-23 | 36.84% (190) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 4e-19 | 32.07% (184) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 9e-18 | 33.33% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 4e-19 | 32.07% (184) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 3e-16 | 32.11% (190) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4384 | - | 9e-76 | 62.56% (211) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1637 | - | 8e-08 | 45.76% (59) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4593 | - | 8e-21 | 32.40% (179) | TetR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1380 | - | 7e-78 | 64.19% (215) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_2712 | - | 5e-08 | 50.00% (54) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 5e-08 | 45.76% (59) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRARVLE
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRARVLE
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRARVLE
Mvan_1059|M.vanbaalenii_PYR-1 ----------------------------MIDKPCRGLRKDAERNRQRVLT
MSMEG_1380|M.smegmatis_MC2_155 --------------------------MSAPETPERPLRKDAERNRKRVLE
MAB_4384|M.abscessus_ATCC_1997 --------------------------MNGREVAHRPLRKDAERNRKRVIA
MAV_4593|M.avium_104 ----------------------------------MVGRSDARRNRQRLLE
MMAR_1637|M.marinum_M --------------------MSGVEGLGELPVSARQERGDAARNRELLLQ
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ
TH_2712|M.thermoresistible__bu ----VSLMSADELLP----ARPATDVAAPTATTAPPEREDAARNRALLLD
* ** *** ::
Mb0068c|M.bovis_AF2122/97 VAYQTFAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
Rv0067c|M.tuberculosis_H37Rv VAYQTFAADGLSVP-VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
MLBr_00316|M.leprae_Br4923 VAYEAFATEGLSVP-IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
Mflv_0142|M.gilvum_PYR-GCK VAYDTFAAEGLTVP-IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR
Mvan_1059|M.vanbaalenii_PYR-1 AARELFAVEGMEAS-LNDVARHAGVGVGTVYRRFATKEELVEAIFESGVD
MSMEG_1380|M.smegmatis_MC2_155 AARELFAAKGLEPN-LNDVARHAGVGVGTVYRRFATKEELLEAIFEDAMN
MAB_4384|M.abscessus_ATCC_1997 AARELFAVHGLEST-LNEVAHHAGLGVGTVYRRFPTKEALFEAIYVDGMD
MAV_4593|M.avium_104 AATAAFTAHGASVS-LESIARDAGVGIGTLYRHFPNREALVEAVYRAELA
MMAR_1637|M.marinum_M AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
MUL_3399|M.ulcerans_Agy99 AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
TH_2712|M.thermoresistible__bu AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET
.* .: * :.:* **:* **::*:* .: * :
Mb0068c|M.bovis_AF2122/97 RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
Rv0067c|M.tuberculosis_H37Rv RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
MLBr_00316|M.leprae_Br4923 HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDIL
Mflv_0142|M.gilvum_PYR-GCK RIAERARTLLAVEGPGQALFVFFRDMVRS-AAVDHGLVDALMNQG-LDLE
Mvan_1059|M.vanbaalenii_PYR-1 EVVCLAEAALRHQDSWEG-FVWFVERQCLLTATDRGLREMVYSKA--YGG
MSMEG_1380|M.smegmatis_MC2_155 QLTDLAEEALRKSDSWQG-FAWFVEQQCQLTVTDRGLREIAFSKC--YGG
MAB_4384|M.abscessus_ATCC_1997 QLSGLAEAALRHENSWEG-FEWFVHQMCEITATNRGLREIAFSKA--HGG
MAV_4593|M.avium_104 EVAAAAAQLLQR-HPPKAALRRWMDRYATFVATKRGMAESLQAIF-ESGA
MMAR_1637|M.marinum_M ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
MUL_3399|M.ulcerans_Agy99 ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
TH_2712|M.thermoresistible__bu AFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALLTDVS-REPQ
. :
Mb0068c|M.bovis_AF2122/97 SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
Rv0067c|M.tuberculosis_H37Rv SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQSYN
MLBr_00316|M.leprae_Br4923 GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN
Mflv_0142|M.gilvum_PYR-GCK AVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQVFD
Mvan_1059|M.vanbaalenii_PYR-1 NRVERVRERLAPLMKELVERARRDGYLRPDVESTDMPVIGLLAGTVGEWA
MSMEG_1380|M.smegmatis_MC2_155 DRVKAAQDRLSVVTTELVERAQRDGHLRPGVSATDLPLLALLAGTVTEFA
MAB_4384|M.abscessus_ATCC_1997 DHVEAGRARLLPLLSKVVERAQEDGYLRPEASATDMPFFGVLTGAVSEFA
MAV_4593|M.avium_104 LVPSQTRDSIVGAVETLLRAGADDASLRADVQADDVVSSLIGIFLVSGSP
MMAR_1637|M.marinum_M TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR
MUL_3399|M.ulcerans_Agy99 TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLNDR
TH_2712|M.thermoresistible__bu TRFGPPMTLHHTHIRSLLAAADADGDLDVQADALLALTDPDYVRHQVTDR
:: . . .
Mb0068c|M.bovis_AF2122/97 ----AELAAKVTDVALDGLRANRK--------------------------
Rv0067c|M.tuberculosis_H37Rv ----AELAAKVTDVALDGLRANRK--------------------------
MLBr_00316|M.leprae_Br4923 ----SALAERVTDVVVDGLRAAR---------------------------
Mflv_0142|M.gilvum_PYR-GCK ----SEVTERVTRVIEDGLRPLR---------------------------
Mvan_1059|M.vanbaalenii_PYR-1 GDVDPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAMHGWDPSG-
MSMEG_1380|M.smegmatis_MC2_155 GHVDADLWRRYTSILLEGMRHHPGQEPVAVFALDRPALEAAMRTWEPAGP
MAB_4384|M.abscessus_ATCC_1997 GEVNADLWRRYMAILIEGMRRRDDQERLEVDALDEAQIDAAMTTWQPAGS
MAV_4593|M.avium_104 -----EQTGRMLDLLVAGVTR-----------------------------
MMAR_1637|M.marinum_M GHTLRTLGDAWEDLARKLCGR-----------------------------
MUL_3399|M.ulcerans_Agy99 GHTLRTLGDAWEDLARKLCGR-----------------------------
TH_2712|M.thermoresistible__bu GVALDALADSWGDVARKLCRR-----------------------------
:
Mb0068c|M.bovis_AF2122/97 --------------
Rv0067c|M.tuberculosis_H37Rv --------------
MLBr_00316|M.leprae_Br4923 --------------
Mflv_0142|M.gilvum_PYR-GCK --------------
Mvan_1059|M.vanbaalenii_PYR-1 --------------
MSMEG_1380|M.smegmatis_MC2_155 PSHRPRPPCPPCAT
MAB_4384|M.abscessus_ATCC_1997 G-------------
MAV_4593|M.avium_104 --------------
MMAR_1637|M.marinum_M --------------
MUL_3399|M.ulcerans_Agy99 --------------
TH_2712|M.thermoresistible__bu --------------