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MELRFTESDSVLITGGSRGIGAATAQVFAAEGVGRIHLVGRDKDSLEQLRGSIDADVTCHALDLSSPSDR AELSETLAEIDILINNAGAIPQGSLDEADLAAWQRAWDLKVWGYLELSQLALKAMRSRRSGVIVNVVGLS GERPDAGYLAGSMANSALMTFTRAVGAYSLDDGLRVVAVNPGPVQTQRLLDALHVRARTELGASDRWSEF VEHYPAQRMATAEEVADTIAFLASRRSSYTSGTVVTLDGGMAWRGRAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3395 | - | - | 100% (258) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6753 | - | 7e-30 | 33.61% (244) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_3994 | - | 6e-29 | 33.33% (249) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 7e-21 | 29.96% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_3658 | - | 8e-22 | 32.67% (251) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 7e-21 | 29.96% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-17 | 28.11% (249) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4335 | - | 3e-19 | 32.60% (181) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 4e-21 | 29.55% (247) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3655 | fabG | 3e-21 | 30.89% (246) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_4608 | - | 4e-21 | 30.68% (264) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 5e-22 | 29.96% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1212 | - | 5e-23 | 32.78% (241) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGA-HVV
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGA-HVV
MMAR_1952|M.marinum_M -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGA-NVV
MUL_2173|M.ulcerans_Agy99 -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGA-NVV
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGA-NVV
Mvan_1212|M.vanbaalenii_PYR-1 ----------------MELTGQTALITGGTAGIGLACAQLMAREGA-DVV
Mflv_3658|M.gilvum_PYR-GCK MT-STENTAGESVAGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGH-KVA
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGH-RVA
MSMEG_3395|M.smegmatis_MC2_155 -------------MELRFTESDSVLITGGSRGIGAATAQVFAAEGVGRIH
TH_4608|M.thermoresistible__bu --------------MDLGFTDAAAVVVGGGRGMGLAAAQCLADDGA-RVA
MAB_4335|M.abscessus_ATCC_1997 ------------MGTAVQLAGKVVAVTGGARGIGRAIATAFAAEGA-KVA
. :.*. *:* * * :. * :
Mb2788c|M.bovis_AF2122/97 LTARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFG-
Rv2766c|M.tuberculosis_H37Rv LTARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFG-
MMAR_1952|M.marinum_M LTARKQESADAAAAEVG----ERAVGVGAHAVDEEAARGCVDLALERFG-
MUL_2173|M.ulcerans_Agy99 LTARKQESADAAAAEVG----ERAVGVGAHAVDEEAARGCVDLALERFG-
MAV_3655|M.avium_104 LTARKQEAADEAAAQVG----PQALGVGAHAVDEDAARQCVQLTLERFG-
Mvan_1212|M.vanbaalenii_PYR-1 ITGR-DPGRGEAAAASD----PRLR----FLRCDLADRTSIESLVQQAP-
Mflv_3658|M.gilvum_PYR-GCK VTHR--------GSGAP----DGLFGVVCDVTDNDAVDRAFKEVEEHQG-
MLBr_01807|M.leprae_Br4923 VTHR--------ASVVP----DWFFGVECDVTDNDAIGAAFKAVEEHQG-
MSMEG_3395|M.smegmatis_MC2_155 LVGRDKDSLEQLRGSID----ADVTCHALDLSSPSDR----AELSETLA-
TH_4608|M.thermoresistible__bu VIGRTRSMLDEAAADLARRGSPDALGIVADIRDEQQVERVFAELGERWQG
MAB_4335|M.abscessus_ATCC_1997 IGDIDKKLCENTAAEIG----NSAIGLPLDVTDHGSFEAFFDTIAATVG-
: .
Mb2788c|M.bovis_AF2122/97 SVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
Rv2766c|M.tuberculosis_H37Rv SVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMG
MMAR_1952|M.marinum_M SVDILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMG
MUL_2173|M.ulcerans_Agy99 SVDILINNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMG
MAV_3655|M.avium_104 SVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMG
Mvan_1212|M.vanbaalenii_PYR-1 PVDILVNNAASFPG-AMTVDQDAATFQRTFDTNVGGTYFLTAAVVPAMLL
Mflv_3658|M.gilvum_PYR-GCK PVEVLVSNAG-ISKDAFLMRMTEDRFTDVIDANLTGAFRVAQRASRSMQR
MLBr_01807|M.leprae_Br4923 PVEVLVANAG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
MSMEG_3395|M.smegmatis_MC2_155 EIDILINNAGAIPQ-GSLDEADLAAWQRAWDLKVWGYLELSQLALKAMRS
TH_4608|M.thermoresistible__bu ELNVLINTVG-PAVMGTVEELSDEQWRSAVDDGVLGMVHCVRSALPLLRQ
MAB_4335|M.abscessus_ATCC_1997 PVDVIVNNAG-IMPITPFDDESLESIQRQLDINVRGVMWGSQLAIKRMKP
::::: ... * : . .
Mb2788c|M.bovis_AF2122/97 EHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
Rv2766c|M.tuberculosis_H37Rv EHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
MMAR_1952|M.marinum_M EHGGVVINTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVN
MUL_2173|M.ulcerans_Agy99 EHGGVVINTASIGGMHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVN
MAV_3655|M.avium_104 EHGGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVN
Mvan_1212|M.vanbaalenii_PYR-1 RGRGAIVNVTSMVAWKGVPGASVYSASKAAVESLTRTWAAEFAPH-VRVN
Mflv_3658|M.gilvum_PYR-GCK KRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELSKAGVTAN
MLBr_01807|M.leprae_Br4923 QRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
MSMEG_3395|M.smegmatis_MC2_155 RRSGVIVNVVGLSGERPDAGYLAGSMANSALMTFTRAVGAYSLDDGLRVV
TH_4608|M.thermoresistible__bu AEWARIVNLSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLAKDEILVN
MAB_4335|M.abscessus_ATCC_1997 RGGGVIVNIASAAGKAGFPGLATYCATKHAVVGLSESLSLEYEPAGISVV
. : . :: : .:. . : .
Mb2788c|M.bovis_AF2122/97 AICPGVVRTR--------------LAEALWKDHEDPLAA-TIALGRIGEP
Rv2766c|M.tuberculosis_H37Rv AICPGVVRTR--------------LAEALWKDHEDPLAA-TIALGRIGEP
MMAR_1952|M.marinum_M AICPGVVRTK--------------LAEALWKDHEDPLAA-NIALGRIGEP
MUL_2173|M.ulcerans_Agy99 AICPGVVRTK--------------LAEALWKDHEDPLAA-NIALGRIGEP
MAV_3655|M.avium_104 AIAPGVVRTR--------------LAEALWKDHEDPLSS-SIALGRIGEP
Mvan_1212|M.vanbaalenii_PYR-1 SVAPGPTDTE--------------GVVAEWGDTNDELGR-ALPLGRTATP
Mflv_3658|M.gilvum_PYR-GCK VVAPGYIDTE--------------MTRALDERIQAGALE-FIPAKRVGTA
MLBr_01807|M.leprae_Br4923 VVAPGFIDTE--------------MTRAMDSKYQEAALQ-AIPLGRIGAV
MSMEG_3395|M.smegmatis_MC2_155 AVNPGPVQTQRLLDALHVR----ARTELGASDRWSEFVE-HYPAQRMATA
TH_4608|M.thermoresistible__bu VVSPGSIASEALVGWADSIGVDGTDPYALMSAIDEHFGH-PAHLPRAGLP
MAB_4335|M.abscessus_ATCC_1997 CVMPGMVNTELISGLDTHWLLKTVEPEDIANAVVKAVRRGVFPVFVPKMF
: ** :.
Mb2788c|M.bovis_AF2122/97 ADIASAVAFLVSDAASWITGET------MIIDGGLLLGNALGFRAAPSTE
Rv2766c|M.tuberculosis_H37Rv ADIASAVAFLVSDAASWITGET------MIIDGGLLLGNALGFRAAPSTE
MMAR_1952|M.marinum_M VDVAEAVGFLVSDAASWITGET------MVIDGGLLLGSAAGFQSRPGSA
MUL_2173|M.ulcerans_Agy99 VDVAEAVGFLVSDAASWITGET------MVIDGGLLLGSAAGFQSRPGSA
MAV_3655|M.avium_104 IDVAAAVAFLVSDAASWITGET------LVIDGGTVLGAAQGFRSAPTPS
Mvan_1212|M.vanbaalenii_PYR-1 GEIAQAVLFLASPRAGFVTGSV------LHADGG---GTAI---------
Mflv_3658|M.gilvum_PYR-GCK DEVAGAVSFLASEDASYIAGAV------IPVDGGMGMGH-----------
MLBr_01807|M.leprae_Br4923 EEIAGAVSFLASEDAGYISGAV------IPVDGGLGMGH-----------
MSMEG_3395|M.smegmatis_MC2_155 EEVADTIAFLASRRSSYTSGTV------VTLDGGMAWRGRAL--------
TH_4608|M.thermoresistible__bu EEIGPVIAFLASRRNSYMTGAN------VNVDGGSDFV------------
MAB_4335|M.abscessus_ATCC_1997 GGMYRTMSVLPRSTGKFLTRKLGIQDFMLNAHGSDARKAYEDRASHSGPS
: .: .* : : : .*.
Mb2788c|M.bovis_AF2122/97 H-
Rv2766c|M.tuberculosis_H37Rv H-
MMAR_1952|M.marinum_M S-
MUL_2173|M.ulcerans_Agy99 S-
MAV_3655|M.avium_104 --
Mvan_1212|M.vanbaalenii_PYR-1 --
Mflv_3658|M.gilvum_PYR-GCK --
MLBr_01807|M.leprae_Br4923 --
MSMEG_3395|M.smegmatis_MC2_155 --
TH_4608|M.thermoresistible__bu --
MAB_4335|M.abscessus_ATCC_1997 TE