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M. thermoresistible (build 8) TH_4608 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 2175026 - 2175823
length: 266

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4608 - - 100% (266) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3956 - 1e-30 36.50% (274) PUTATIVE putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3102 - 7e-26 31.75% (252) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1519 fabG1 4e-22 28.24% (262) 3-oxoacyl-
M. gilvum PYR-GCK Mflv_4353 - 1e-123 81.44% (264) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv1483 fabG1 4e-22 28.24% (262) 3-oxoacyl-
M. leprae Br4923 MLBr_01807 fabG1 3e-18 28.14% (263) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_2723c - 3e-21 28.68% (258) 3-oxoacyl-
M. marinum M MMAR_1568 - 4e-70 51.67% (269) short-chain type dehydrogenase/reductase
M. avium 104 MAV_1587 - 1e-120 78.41% (264) oxidoreductase, short chain dehydrogenase/reductase family
M. smegmatis MC2 155 MSMEG_2228 - 1e-121 80.30% (264) oxidoreductase, short chain dehydrogenase/reductase family
M. ulcerans Agy99 MUL_0315 fabG2 1e-24 31.27% (259) 3-oxoacyl-
M. vanbaalenii PYR-1 Mvan_1991 - 1e-124 81.06% (264) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4353|M.gilvum_PYR-GCK          --------------MDLGLRDATVVVVGGGRGMGLAAAHCFADDGARVAL
Mvan_1991|M.vanbaalenii_PYR-1       --------------MDLGLRDATAVVVGGGRGMGLAAAHCFADDGARVAL
TH_4608|M.thermoresistible__bu      --------------MDLGFTDAAAVVVGGGRGMGLAAAQCLADDGARVAV
MAV_1587|M.avium_104                --------------MDLGLANAAAVVVGGSRGMGLATARCLADEGARVAV
MSMEG_2228|M.smegmatis_MC2_155      --------------MDLGFGGAAAAVVGGGRGMGFATAQCLADDGARVAV
MMAR_1568|M.marinum_M               --------------MDLGFSGSKAVVTGGSKGMGLAIAETLAAEGASVAV
Mb1519|M.bovis_AF2122/97            MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv         MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_2723c|M.abscessus_ATCC_199      MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKVAV
MUL_0315|M.ulcerans_Agy99           MRPDSS----------PSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
                                                             *.**  *:*:* *. :  :*  ** 

Mflv_4353|M.gilvum_PYR-GCK          VGRTRDVLDEAAAQLRGRGSPDAVGVVADCADEAAVQRAFGELAERWNGE
Mvan_1991|M.vanbaalenii_PYR-1       IGRSPEVLDGAAAQLRERGSPDAVGVVADTTDDAAVRRAFAELGERWNGE
TH_4608|M.thermoresistible__bu      IGRTRSMLDEAAADLARRGSPDALGIVADIRDEQQVERVFAELGERWQGE
MAV_1587|M.avium_104                IGRSRDALDSAVTDLTRRGSPDALGLVADIGDDAAVGQAFGELARRWDGE
MSMEG_2228|M.smegmatis_MC2_155      IGRSKDVLETAASDLARRGSPDAIAIVADTGDAEQVERAFAEIGERWDGE
MMAR_1568|M.marinum_M               IARGKRALDSAVERLSQAGAPDAVAISADMADAASITSAFAAVSERWG-Q
Mb1519|M.bovis_AF2122/97            THRGSGAPKGLFG------------VECDVTDSDAVDRAFTAVEEHQG-P
Rv1483|M.tuberculosis_H37Rv         THRGSGAPKGLFG------------VECDVTDSDAVDRAFTAVEEHQG-P
MLBr_01807|M.leprae_Br4923          THRASVVPDWFFG------------VECDVTDNDAIGAAFKAVEEHQG-P
MAB_2723c|M.abscessus_ATCC_199      THRGSGAPEGLLG------------VQCDITDNDQIDAAFKEVEEKQG-P
MUL_0315|M.ulcerans_Agy99           LDLKT--PDGGLA------------FSADVTNRSQVDAALAAIRQRLG-P
                                            .                . .*  :   :  .:  : .:    

Mflv_4353|M.gilvum_PYR-GCK          LNVLVNAVGPTVRGTFDELSDADWRQAVDEGAMGMVRCVRAALPLLRAAE
Mvan_1991|M.vanbaalenii_PYR-1       LNILVNAVGPTVRGTFDELTDADWRQAVDEGAMGMVHCVRAALPLLRAAE
TH_4608|M.thermoresistible__bu      LNVLINTVGPAVMGTVEELSDEQWRSAVDDGVLGMVHCVRSALPLLRQAE
MAV_1587|M.avium_104                LNALVITVGPGAAGTFEDLTDEQWRQAVEDGVLGMVRCVRAALPLLRKAQ
MSMEG_2228|M.smegmatis_MC2_155      LNVLINTVGPGAAGDFEELTDGQWQEAFDAGVMGMVRCVRAALPLLRKAE
MMAR_1568|M.marinum_M               LNCLVHTIGPGD-GYFEELDDAAWDAAFTLGTMSGVRAIRAALPLLRAAD
Mb1519|M.bovis_AF2122/97            VEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK
Rv1483|M.tuberculosis_H37Rv         VEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNK
MLBr_01807|M.leprae_Br4923          VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_2723c|M.abscessus_ATCC_199      VEVLVANAGITADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKR
MUL_0315|M.ulcerans_Agy99           VTILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAG
                                    :  *:   *      .  :    :  ..  .  . .:  : .   :    

Mflv_4353|M.gilvum_PYR-GCK          WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
Mvan_1991|M.vanbaalenii_PYR-1       WARIVNFSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLARDEILVNVV
TH_4608|M.thermoresistible__bu      WARIVNLSAHSTQRQSVILPAYTAAKAMVTSISKNLSLLLAKDEILVNVV
MAV_1587|M.avium_104                WARIVNFSAHSTQRQSVLLPAYTAAKSMLTSVSKNLSLLLAKDEILVNVI
MSMEG_2228|M.smegmatis_MC2_155      WARIVNFSAHSTQRQSTRLPAYTAAKAAVNSVSKNLSLLLAKDEIMVNVV
MMAR_1568|M.marinum_M               WARVVTLSAHSIQRQNPRLVAYTASKAALSSVTKNLSKSLAKEGILVNCV
Mb1519|M.bovis_AF2122/97            FGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVV
Rv1483|M.tuberculosis_H37Rv         FGRMIFIGSVSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVV
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MAB_2723c|M.abscessus_ATCC_199      FGRLIFMGSVAGQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVV
MUL_0315|M.ulcerans_Agy99           WGRIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAV
                                    :.* : :.:            * *:*: : .::: ::   .   : .* :

Mflv_4353|M.gilvum_PYR-GCK          SPGSIAS----EALVGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
Mvan_1991|M.vanbaalenii_PYR-1       SPGSIAS----EALLGWADSVGVDGSDPYALMAAIDEHFGHPAHLPRAGL
TH_4608|M.thermoresistible__bu      SPGSIAS----EALVGWADSIGVDGTDPYALMSAIDEHFGHPAHLPRAGL
MAV_1587|M.avium_104                SPGSIAS----ESLVGWANSVGVDGRDPYALMEAIGKHFGHPAHMPRAGL
MSMEG_2228|M.smegmatis_MC2_155      SPGSISS----EALVGWAESVGVDGSDPYQLMAAIDEHFGHPAHLPRAGL
MMAR_1568|M.marinum_M               CPGTIVTASFTEQLKDLLAADGLDATNPYDVMAWIDKYFHQPCDLGRAGL
Mb1519|M.bovis_AF2122/97            APGYIDT-----DMTRALDER-------------IQQGALQFIPAKRVGT
Rv1483|M.tuberculosis_H37Rv         APGYIDT-----DMTRALDER-------------IQQGALQFIPAKRVGT
MLBr_01807|M.leprae_Br4923          APGFIDT-----EMTRAMDSK-------------YQEAALQAIPLGRIGA
MAB_2723c|M.abscessus_ATCC_199      APGFIDT-----DMTRELGEK-------------HVETALTAIPMGRIGE
MUL_0315|M.ulcerans_Agy99           PPGFIDT-----PMLRNAAAQGHLG---------DIEQNIARTPVRRIGK
                                     ** * :      :                      :         * * 

Mflv_4353|M.gilvum_PYR-GCK          PTEIGSVVAFLASRRNSYMTGADINVDGGSDFT-
Mvan_1991|M.vanbaalenii_PYR-1       PTEIGPVVAFLASRRNSYMTGANINVDGGSDFT-
TH_4608|M.thermoresistible__bu      PEEIGPVIAFLASRRNSYMTGANVNVDGGSDFV-
MAV_1587|M.avium_104                PEEIGPVAAFLASRRNSYMTGANINVDGGSDFT-
MSMEG_2228|M.smegmatis_MC2_155      PSEIGPVAAFLASRRNSYMTGANINVDGGSDFT-
MMAR_1568|M.marinum_M               PEEVASITAYLVSRRNGYVTGATVNADGGSDFI-
Mb1519|M.bovis_AF2122/97            PAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
Rv1483|M.tuberculosis_H37Rv         PAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
MLBr_01807|M.leprae_Br4923          VEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
MAB_2723c|M.abscessus_ATCC_199      PSEVAGVVSWLASPDAAYVSGAVIPVDGGLGMGH
MUL_0315|M.ulcerans_Agy99           PEDIAAACAFLVSEEAGYITGQILGVNGGRNT--
                                      ::.   ::*.*   .*::*  : .:** .

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4608	-	-	100% (266)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3956	-	1e-30	36.50% (274)	PUTATIVE putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3102	-	7e-26	31.75% (252)	PUTATIVE short-chain dehydrogenase/reductase SDR