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MTQPPAGPSGPGDSAPSADATENGQNRPITREAVLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHV PNKAAVLDGVVEMIFEQLSLDTTTPDWIAALRRLGHDFRNLARAHPNVVPLLVTRPLATPLGMRPPGILR HLEQILALLTRCGFTGPDALHVYRTLFGFLYGHVLTELQEIVERPEETDHVMRLGLHRLPIGEFPHVRDL APTWAAYDGLAELDRGLDILLTGLATRLDMPGGMPTRAPEPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3332 | - | - | 100% (252) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2583 | - | 2e-19 | 29.52% (210) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2225 | - | 1e-07 | 21.91% (178) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0700 | - | 1e-08 | 24.16% (178) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2560 | - | 4e-12 | 29.49% (156) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0681 | - | 1e-08 | 24.16% (178) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3216c | - | 2e-22 | 35.09% (171) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 2e-18 | 29.27% (205) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 3e-13 | 31.97% (147) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1893 | - | 3e-10 | 25.37% (205) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_3622 | - | 2e-17 | 28.78% (205) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1315 | - | 2e-15 | 30.36% (224) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M ------------------------------MFTLRTMYLSTVWEGDVRAR
MUL_3622|M.ulcerans_Agy99 -----------------MISIRTS-----YVFTLRTMYLSTVWEGDVRAR
Mb0700|M.bovis_AF2122/97 --------------------------------------------MARPAK
Rv0681|M.tuberculosis_H37Rv --------------------------------------------MARPAK
TH_1893|M.thermoresistible__bu --------------------VNTQ-----MSAGPGGAPGARTKSPARAGR
Mvan_1315|M.vanbaalenii_PYR-1 MSYAHGCTAVRLDRMTNEEERGTP-----PLPRALEVLWHDRAGGGRARR
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
MSMEG_3332|M.smegmatis_MC2_155 ------------------MTQPPAG----PSGPGDSAPSADATENGQNRP
MAV_5055|M.avium_104 ---------------------------------------------MRRAG
MAB_3216c|M.abscessus_ATCC_199 ----------------MARAQKCTVGVTDAVDETESGTVAGGAEGRRPRS
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVR----DRR
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVR----DRR
Mb0700|M.bovis_AF2122/97 LSRESIVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRR
Rv0681|M.tuberculosis_H37Rv LSRESIVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRR
TH_1893|M.thermoresistible__bu LSRDTIVNAALTFLDREGWDALTINALATQLGTKGPSLYNHVQSLDDLRR
Mvan_1315|M.vanbaalenii_PYR-1 LSRQRIVEAAIELADRDGLGALSMARLAERLGCGTMSLYRHVAN----KD
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPG----KA
MSMEG_3332|M.smegmatis_MC2_155 ITREAVLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHVPN----KA
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPD----KD
MAB_3216c|M.abscessus_ATCC_199 LTRAEILDTAIALVDSEGLDQLTMRRLGSACGVEAMALYRHVHGRQDLLG
. : *: : * :* ::: :. * ::* ::
MMAR_3679|M.marinum_M ELEALVADAVVADVK-VPAPTDDWRADVHAIATAMWETMRQHP------N
MUL_3622|M.ulcerans_Agy99 ELEALVADAVVADVK-VPAPIDDWRADVHAIATAMWETMRQHP------N
Mb0700|M.bovis_AF2122/97 AVRIRVIDDIITMLN-RVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFT
Rv0681|M.tuberculosis_H37Rv AVRIRVIDDIITMLN-RVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFT
TH_1893|M.thermoresistible__bu SVRMRVVDDIIGMLN-AAGQGRTRDDAVLAMASAYRSYAHHHPGRYSAFT
Mvan_1315|M.vanbaalenii_PYR-1 ELVTFMVSAAPGHPP-GTTDRADWRDALTDWAVGLWDVYHRHP------W
Mflv_2560|M.gilvum_PYR-GCK ELLDLMLDSVYGQMSRGDLSGLPWRHRVTAIADENRALLDEHP------W
MSMEG_3332|M.smegmatis_MC2_155 AVLDGVVEMIFEQLS-LDTTTPDWIAALRRLGHDFRNLARAHPNVVPLLV
MAV_5055|M.avium_104 ALIDVVVDESLAVVP-VPDPSGSVTAELLRCFGGLYDLLLDHPG------
MAB_3216c|M.abscessus_ATCC_199 GIVDHLVDKLYDDQLAARRQEDGWQDYLVRLAHGVREIAIGHPHLFPTLA
: : . : **
MMAR_3679|M.marinum_M AIPLVLTRRTVSASSYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGS
MUL_3622|M.ulcerans_Agy99 AIPLVLTRRTVWASSYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGS
Mb0700|M.bovis_AF2122/97 RMPLGGDDPEYTAATRGAAAPVIAVLSSYGLDGEQAFYAALEFWSALHGF
Rv0681|M.tuberculosis_H37Rv RMPLGGDDPEYTAATRGAAAPVIAVLSSYGLDGEQAFYAALEFWSALHGF
TH_1893|M.thermoresistible__bu RMPLGGDDPEFSAAARAAAGPVIAVLGSYGLEGEEAFYAALEFWSALHGF
Mvan_1315|M.vanbaalenii_PYR-1 ILHATVIGPPADPGQLAWLDAGLAALSGTGLSERDKLAAVMALLHFVRGA
Mflv_2560|M.gilvum_PYR-GCK VTQLATTRPPLGPGTAAKYDHELRAFDGLGLSDLDMDSALTYVLGFVTSV
MSMEG_3332|M.smegmatis_MC2_155 TRPLATPLGMRPPGILRHLEQILALLTRCGFTGPDALHVYRTLFGFLYGH
MAV_5055|M.avium_104 LARAAGERPLEGPFATRLGNNVLTLLQHNKIDEADAANLLVSAFSLTLGC
MAB_3216c|M.abscessus_ATCC_199 TRPPEAPWVRPPLRSMKWMETFLDTLISYGFDDRAAVSAYRAYTTFLLGQ
: : . .
MMAR_3679|M.marinum_M AQAELAGPLAGTGREKEQVAVAARIGGLAGAEH-------PHIAALAQAS
MUL_3622|M.ulcerans_Agy99 AQAELAGPLAGTGREKEQVAVAARIGGLAGAEH-------PHIAALAQAS
Mb0700|M.bovis_AF2122/97 VLLEMTGVMDDIDTDAVFTDMVLRLA--AGMER-------RTTHGGTAST
Rv0681|M.tuberculosis_H37Rv VLLEMTGVMDDIDTDAVFTDMVLRLA--AGMER-------RTTHGGTAST
TH_1893|M.thermoresistible__bu VLLEMTGVMDDVDSDKVFTDMVLRLA--AGMEK-------RS--------
Mvan_1315|M.vanbaalenii_PYR-1 SALDIE-AADHHDTAPDYPALLRRLV--TGERF-------PALAAALQAE
Mflv_2560|M.gilvum_PYR-GCK ARIADDAREARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQ
MSMEG_3332|M.smegmatis_MC2_155 VLTELQEIVERPEETDHVMRLGLHRLPIGEFPHVR-----DLAPTWAAYD
MAV_5055|M.avium_104 ALYRTS--RSGRTASSRLSQVGDEAPAVRRLRG-------RLTVASADDT
MAB_3216c|M.abscessus_ATCC_199 LLLEVSARGASLSSVEDELPEKTLRS-------------LSSYPNLQRMQ
MMAR_3679|M.marinum_M QRSTP---AADFERALDILLAGIESFERRRDRR--
MUL_3622|M.ulcerans_Agy99 QRSTP---AADFERALDILLAGIESFERRRDRR--
Mb0700|M.bovis_AF2122/97 -----------------------------------
Rv0681|M.tuberculosis_H37Rv -----------------------------------
TH_1893|M.thermoresistible__bu -----------------------------------
Mvan_1315|M.vanbaalenii_PYR-1 AFDADGDRLADFRSGLDQFLDGIDSRVRRSR----
Mflv_2560|M.gilvum_PYR-GCK AFGSAYDADHAYRFGLARVLDGLEPVINRTAR---
MSMEG_3332|M.smegmatis_MC2_155 GLAELDRGLDILLTGLATRLDMPGGMPTRAPEPG-
MAV_5055|M.avium_104 ----------VFRDALTRLIAGYVTTAAKTGGRRR
MAB_3216c|M.abscessus_ATCC_199 KQLSEDHSATEFEEALESLLDRLENGAPR------