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VARPAKLSRESIVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITML NRVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFTRMPLGGDDPEYTAATRGAAAPVIAVLSSYGLDGEQ AFYAALEFWSALHGFVLLEMTGVMDDIDTDAVFTDMVLRLAAGMERRTTHGGTAST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0681 | - | - | 100% (196) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) |
| M. tuberculosis H37Rv | Rv0653c | - | 2e-07 | 25.14% (183) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0700 | - | 1e-110 | 100.00% (196) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5079 | - | 3e-83 | 81.72% (186) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3852c | - | 5e-57 | 55.85% (188) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1010 | - | 9e-95 | 86.60% (194) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4494 | - | 1e-101 | 93.68% (190) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1397 | - | 3e-88 | 83.24% (185) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1893 | - | 2e-88 | 82.35% (187) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_0762 | - | 6e-95 | 86.60% (194) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1278 | - | 4e-83 | 80.00% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5079|M.gilvum_PYR-GCK ---------------MAARPPRTAKLSRDSIVNAALTFLDREGWDALTIN
Mvan_1278|M.vanbaalenii_PYR-1 ---------------MAVRPPRTAKLSRDAIVNAALTFLDREGWDALTIN
Rv0681|M.tuberculosis_H37Rv -------------------MARPAKLSRESIVEGALTFLDREGWDSLTIN
Mb0700|M.bovis_AF2122/97 -------------------MARPAKLSRESIVEGALTFLDREGWDSLTIN
MAV_4494|M.avium_104 MAAQPEPPTAAGRQRAGRPAARPAKLSREGIIDGALTFLDREGWDALTIN
MMAR_1010|M.marinum_M MAASAEGPSAAGRPRAAKSTSRPAKLSRDAIVDGALTFLDREGWDSLTIN
MUL_0762|M.ulcerans_Agy99 MAASAEGPSAAGRPRAAKSTSRPAKLSRDAIVDGALTFLDREGWDSLTIN
MSMEG_1397|M.smegmatis_MC2_155 ----MRA-------------TRTTRLSRDTIVNAALTFLDREGWDALTIN
TH_1893|M.thermoresistible__bu VNTQMSAGPGGAPGARTKSPARAGRLSRDTIVNAALTFLDREGWDALTIN
MAB_3852c|M.abscessus_ATCC_199 -------MTTEPATAHRRTPARATRLNRDAVVNAALSFLDRAGWDALTIN
.*. :*.*: :::.**:**** ***:****
Mflv_5079|M.gilvum_PYR-GCK ALANQLGTKGPSLYNHVHSLDDLRRTVRMRVVGDIIDMLNTVAQGRNPDD
Mvan_1278|M.vanbaalenii_PYR-1 ALANQLGTKGPSLYNHVHSLDDLRRTVRMHVVGDIIEMLNTVGKGRTPDD
Rv0681|M.tuberculosis_H37Rv ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGAGRARDD
Mb0700|M.bovis_AF2122/97 ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGAGRARDD
MAV_4494|M.avium_104 ALATQLGTKGPSLYNHVDSLEDLRRAVRIRVIDDIITMLNRVGEGRARDD
MMAR_1010|M.marinum_M ALATQLGTKGPSLYNHVVSLEDLRGAVRVRVIDDIIMMLNRVGEGRSRDD
MUL_0762|M.ulcerans_Agy99 ALATQLGTKGPSLYNHVVSLEDLRGAVRVRVIDDIIMMLNRVGEGRSRDD
MSMEG_1397|M.smegmatis_MC2_155 ALANQLGTKGPSLYNHVHSLDDLRRTVRMRVIDDIISMLNRVGEGRTRDD
TH_1893|M.thermoresistible__bu ALATQLGTKGPSLYNHVQSLDDLRRSVRMRVVDDIIGMLNAAGQGRTRDD
MAB_3852c|M.abscessus_ATCC_199 ALAVELGTKGPSLYNHVDSLDDLRHEVRDRVLAEIVGMLHTVSSGRSSED
*** :************ **:*** ** :*: :*: **: .. ** :*
Mflv_5079|M.gilvum_PYR-GCK AVVVMASAYRSYAHHHPGRYSAFTRMPLGGGDDPEFTEVTRAAAAPVIAV
Mvan_1278|M.vanbaalenii_PYR-1 AVMVMASAYRSYAHHHPGRYSAFTRMPLGG-DDPEFTEATRAAAAPVISV
Rv0681|M.tuberculosis_H37Rv AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVIAV
Mb0700|M.bovis_AF2122/97 AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVIAV
MAV_4494|M.avium_104 AVLVMAGAYRSYAHHHPGRYSAFTRMPLGG-DDPEYTAATRGAAAPVISV
MMAR_1010|M.marinum_M AVLVMAGAYRSYAHHHPGRYSAFTRMPPGG-EDPEYAAATRAAAAPVIAV
MUL_0762|M.ulcerans_Agy99 AVLVMAGAYRSYAHHHPGRYSAFTRMPPGG-EDPEYAAATRAAAAPVIAV
MSMEG_1397|M.smegmatis_MC2_155 AVIAMASAYRSYAHHHPGRYSAFTRMPFGD-DDPEYSAATKAAAAPVIEV
TH_1893|M.thermoresistible__bu AVLAMASAYRSYAHHHPGRYSAFTRMPLGG-DDPEFSAAARAAAGPVIAV
MAB_3852c|M.abscessus_ATCC_199 AILAMAGAYRSYAHHHPGRYAALTRMPFLD-AVNRPTIDARELAKPATEA
*::.**.*************:*:**** . . : :: * *. .
Mflv_5079|M.gilvum_PYR-GCK LSSYGLDDEAGFYAALEFWSAMHGFVLLEMTGVMN--GIDTDAVFTDMVM
Mvan_1278|M.vanbaalenii_PYR-1 LETFGLESESAFYAALEFWSAMHGFVLLEMTGVMS--GIDTDAVFTDMVA
Rv0681|M.tuberculosis_H37Rv LSSYGLDGEQAFYAALEFWSALHGFVLLEMTGVMD--DIDTDAVFTDMVL
Mb0700|M.bovis_AF2122/97 LSSYGLDGEQAFYAALEFWSALHGFVLLEMTGVMD--DIDTDAVFTDMVL
MAV_4494|M.avium_104 LSSYGLDGEEAFHAALEFWSALHGFVLLEMTGVMD--DIDTDALFSDMVL
MMAR_1010|M.marinum_M LSSYGLEGEQAFHAALEFWSALHGFVLLEMTGLME--EIDTDAVFSDMVL
MUL_0762|M.ulcerans_Agy99 LSSYGLEGEQAFHAALEFWSALHGFVLLEMTGLME--EIDTDAVFSDMVL
MSMEG_1397|M.smegmatis_MC2_155 LASFGLEGEQAFYAALEFWSALHGFVLLEMTGVMD--DVDTDAVFTDMLL
TH_1893|M.thermoresistible__bu LGSYGLEGEEAFYAALEFWSALHGFVLLEMTGVMD--DVDSDKVFTDMVL
MAB_3852c|M.abscessus_ATCC_199 IGVYGLNEDTAFHAGVELWAAMHGFVMLEMTGFMAGIEMDPDTAFAEMVH
: :**: : .*:*.:*:*:*:****:*****.* :*.* *::*:
Mflv_5079|M.gilvum_PYR-GCK RLAAGMQTR---------
Mvan_1278|M.vanbaalenii_PYR-1 RLAAGMQLR---------
Rv0681|M.tuberculosis_H37Rv RLAAGMERRTTHGGTAST
Mb0700|M.bovis_AF2122/97 RLAAGMERRTTHGGTAST
MAV_4494|M.avium_104 RLAAGLERRTAHG-----
MMAR_1010|M.marinum_M RLAAGMEKRISHTGAESL
MUL_0762|M.ulcerans_Agy99 RLAAGMEKRISHTGAESL
MSMEG_1397|M.smegmatis_MC2_155 RLASGMERREA-------
TH_1893|M.thermoresistible__bu RLAAGMEKRS--------
MAB_3852c|M.abscessus_ATCC_199 RFASGLAERK--------
*:*:*: *