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MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQRTSVDAVVAAAVGIADTQGLS AVTIRAVAGVLGLAPMAIYTYVPGKAELLDLMLDSVYGQMSRGDLSGLPWRHRVTAIADENRALLDEHPW VTQLATTRPPLGPGTAAKYDHELRAFDGLGLSDLDMDSALTYVLGFVTSVARIADDAREARRDSGVSDQA WWDRAGPLLAEVFDDEKFPLAARIGAAAGQAFGSAYDADHAYRFGLARVLDGLEPVINRTAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2560 | - | - | 100% (272) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1322 | - | 2e-05 | 24.83% (149) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2957c | - | 3e-13 | 34.92% (126) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3679 | - | 1e-14 | 29.17% (192) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 7e-12 | 38.00% (100) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3332 | - | 6e-12 | 29.49% (156) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3256 | - | 4e-07 | 31.93% (119) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3622 | - | 2e-14 | 29.17% (192) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4078 | - | 1e-108 | 75.10% (257) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
Mvan_4078|M.vanbaalenii_PYR-1 -----------MVTRGAGPERSSAGDPVRTLKLLWRTPGEARTSRGPRQR
MMAR_3679|M.marinum_M ------------------------MFTLRTMYLSTVWEGDVR------AR
MUL_3622|M.ulcerans_Agy99 ----------------MISIRTSYVFTLRTMYLSTVWEGDVR------AR
MSMEG_3332|M.smegmatis_MC2_155 ---------------MTQPPAGPSGPGDSAPSADATENGQNR-------P
MAV_5055|M.avium_104 ----------------------------------MRRAGLKR--------
MAB_2957c|M.abscessus_ATCC_199 -------------------------------------MTDPR--------
TH_3256|M.thermoresistible__bu --------------------------------------------------
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
Mvan_4078|M.vanbaalenii_PYR-1 TTVDAVVAAAIEIADADGLGAVTIRAVATRLGIATMATYTYVPGKAELLD
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MSMEG_3332|M.smegmatis_MC2_155 ITREAVLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHVPNKAAVLD
MAV_5055|M.avium_104 ---EAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
MAB_2957c|M.abscessus_ATCC_199 LTLESIVGKAIEIADSDGLSGVSMRKIADALGVGAMSLYRHVADKDALLV
TH_3256|M.thermoresistible__bu -------------------------MVAAAVGPPPQ--------------
:. :* .
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGD--LSGLPWRHRVTAIADENRALLDEHPWVTQLATTR
Mvan_4078|M.vanbaalenii_PYR-1 LMLDTVYRQMPRRD--LSGMAWRDRVSAIAGENRELLEQHPWVAQLATTR
MMAR_3679|M.marinum_M LVADAVVADVKVP---APTDDWRADVHAIATAMWETMRQHPNAIPLVLTR
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVP---APIDDWRADVHAIATAMWETMRQHPNAIPLVLTR
MSMEG_3332|M.smegmatis_MC2_155 GVVEMIFEQLSLD---TTTPDWIAALRRLGHDFRNLARAHPNVVPLLVTR
MAV_5055|M.avium_104 VVVDESLAVVPVPD--PSGSVTAELLRCFGG-LYDLLLDHPGLARAAGER
MAB_2957c|M.abscessus_ATCC_199 EMTAEVTRRFAYPDEMMGVPDWRARVRVAVEHDFDLYSTHPWVLLAYAVP
TH_3256|M.thermoresistible__bu ----------------LDPTDWVAALRHWSTALWEVYHRHPWILQAAAAG
: **
Mflv_2560|M.gilvum_PYR-GCK PPLG------PGTAAKYDHELRAFDGLGLSDLDMDSALTYVLGFVTSVAR
Mvan_4078|M.vanbaalenii_PYR-1 PPLG------PGMIAKYEHELCAFDGLGLSDLDMDSALTYVLGFVMSVAR
MMAR_3679|M.marinum_M RTVS------ASSYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
MUL_3622|M.ulcerans_Agy99 RTVW------ASSYMVADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
MSMEG_3332|M.smegmatis_MC2_155 PLATPLGMRPPGILRHLEQILALLTRCGFTGPDALHVYRTLFGFLYGHVL
MAV_5055|M.avium_104 PLEG------PFATRLGNNVLTLLQHNKIDEADAANLLVSAFSLTLGCAL
MAB_2957c|M.abscessus_ATCC_199 RNGMQ-----PETLVCFDWLLEAFSHLGVAAPEAAELTFQVWSYSQGVGL
TH_3256|M.thermoresistible__bu PPAD------PQQLAWLDTALAALQGTGLAERDKLAAVTALMHLVRGAAA
. : : : . : .
Mflv_2560|M.gilvum_PYR-GCK IADDAREARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQAF
Mvan_4078|M.vanbaalenii_PYR-1 IAIDTNAARADSGVTDDTWWEQAGPVLATVFDADEFPLAARVGEAAGRAL
MMAR_3679|M.marinum_M AELAGPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQASQRST
MUL_3622|M.ulcerans_Agy99 AELAGPLAGTGREKEQVAVAARIG-----GLAGAEHPHIAALAQASQRST
MSMEG_3332|M.smegmatis_MC2_155 TELQEIVERP----EETDHVMRLG---LHRLPIGEFPHVRDLAPTWAAYD
MAV_5055|M.avium_104 YRTSR------SGRTASSRLSQVG---------DEAPAVRRLRGRLTVAS
MAB_2957c|M.abscessus_ATCC_199 GAVGGQLVSPGARTDFSGLSELIAG-------NAEVPESPRLAALLGLGD
TH_3256|M.thermoresistible__bu LHIDAG------RLDWPEYPVLLRR----LIDADRFPALTAALDAGAFDP
. *
Mflv_2560|M.gilvum_PYR-GCK GSAYDADHAYRFGLARVLDGLEPVINRTAR---------
Mvan_4078|M.vanbaalenii_PYR-1 GGAYNAEHAYRFGLARVLDGLAPVIGDRARGSGRSPAN-
MMAR_3679|M.marinum_M -----PAADFERALDILLAGIESFERRRDRR--------
MUL_3622|M.ulcerans_Agy99 -----PAADFERALDILLAGIESFERRRDRR--------
MSMEG_3332|M.smegmatis_MC2_155 G-----LAELDRGLDILLTGLATRLDMPGGMPTRAPEPG
MAV_5055|M.avium_104 AD----DTVFRDALTRLIAGYVTTAAKTGGRRR------
MAB_2957c|M.abscessus_ATCC_199 ------LPEVTNPREVIAKGVEILCDGIARRYHKL----
TH_3256|M.thermoresistible__bu VD-ADPLTDLHSAVDYLLDGIAAKL--------------
: *