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ELRFDILRSRDSMERMAAPVIGTLRRWSMLVIALTSTMCANVFINGAAFLIPTLHAERGLDLARSGLLSS MPSFGMVTTLIAWGYVVDRFGERLVLGLGSALTAAAALAAASVQSLFAVGLFLLLGGMAAASSNSASGRL VVGWFPPEQRGLVMGIRQTATPLGVGLGALVIPRLAESHGVSAALLFPAVVCGIAAVVSAVFVLDPPRPP RAEAPAEHLANPYRGSSVLWRIHAVSVLLVVPQGVLWTFALVWLITDRGWSAASAGILVTVTQLLGAGGR IAAGKWSDVIGYRLRPIRTIALAAAVTMAALALTDWLSSPVSIALMVAASVITVSDNGLAFTGIAEIAGP FWSGRALGTQNTSQHLATAVSSPVFGGLIGVAGYPVAFAVCALLPALAIPLVPVEPARES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2380 | - | - | 100% (411) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_6718 | - | 2e-11 | 23.56% (433) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_1169 | - | 4e-10 | 24.40% (414) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3018 | - | 1e-129 | 58.87% (389) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4231 | - | 1e-157 | 70.60% (398) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2994 | - | 1e-129 | 58.87% (389) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3302 | - | 1e-152 | 68.81% (388) | major facilitator transporter |
| M. marinum M | MMAR_1717 | - | 1e-127 | 59.23% (390) | integral membrane transport protein |
| M. avium 104 | MAV_3846 | - | 1e-125 | 57.73% (388) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_2039 | - | 1e-168 | 73.72% (392) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0354 | - | 9e-09 | 24.49% (392) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2131 | - | 1e-160 | 70.36% (415) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3018|M.bovis_AF2122/97 --------------------------------------------------
Rv2994|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1717|M.marinum_M --------------------------------------------------
MAV_3846|M.avium_104 --------------------------------------------------
Mflv_4231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2380|M.smegmatis_MC2_155 --------------------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------------------
MAB_3302|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_0354|M.ulcerans_Agy99 MLTSGSMTTTATIAAGEAMRVSSSSSPDLPDAGDTTKFLRPRNAALRSKA
Mb3018|M.bovis_AF2122/97 -------------------------------------MSRDPTG-----V
Rv2994|M.tuberculosis_H37Rv -------------------------------------MSRDPTG-----V
MMAR_1717|M.marinum_M -------------------------------------MPDESSATQELSL
MAV_3846|M.avium_104 --------MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGA
Mflv_4231|M.gilvum_PYR-GCK ------------------------------------------MAPSSIGP
Mvan_2131|M.vanbaalenii_PYR-1 ----------------------MSHIMRIWFSIVRRLCNHGAMPATAISS
MSMEG_2380|M.smegmatis_MC2_155 --------------------------MELRFDILRSRDSMERMAAPVIGT
TH_2039|M.thermoresistible__bu ------------------------------------------MPVSSISP
MAB_3302|M.abscessus_ATCC_1997 --------------------------------------MVTMVHVDEVGT
MUL_0354|M.ulcerans_Agy99 RGGSRSAARMANTKTNRKPRSARALCARAVAAPLGGARPLGERAGGRHRP
Mb3018|M.bovis_AF2122/97 GARWAIMIVSLGVTASSFLFINGVAFLIPRLENA-RGTPLSHAGLLASMP
Rv2994|M.tuberculosis_H37Rv GARWAIMIVSLGVTASSFLFINGVAFLIPRLENA-RGTPLSHAGLLASMP
MMAR_1717|M.marinum_M SARWWIVIVSLIVTASSFLFINGVAFLIPRLENA-RDTPLAEAGLLASMP
MAV_3846|M.avium_104 GTRWSIMVVSLLATASSFLFINGVAFLIPSLQGA-RGIRLDEAGLLASMP
Mflv_4231|M.gilvum_PYR-GCK TRRWLMLAIGLLTTLCANVFINGVAFLIPTLHDE-RGLDLAGAALMSSLP
Mvan_2131|M.vanbaalenii_PYR-1 MRRWSMLAIGLLATLCANVFINGVAFLIPTLHDE-RGLDLAAAGLMSSLP
MSMEG_2380|M.smegmatis_MC2_155 LRRWSMLVIALTSTMCANVFINGAAFLIPTLHAE-RGLDLARSGLLSSMP
TH_2039|M.thermoresistible__bu ARRWSMLVIALAATLFSVVFINGVAFVIPTLHRE-HGLSLAQAGLLSALP
MAB_3302|M.abscessus_ATCC_1997 ARRWAMLAIALGSTAGANVFINGVAFLIPALHAE-RGLDLANAGLLSAMP
MUL_0354|M.ulcerans_Agy99 AREGYPAVIWLLLGGNLVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLAAF
. : * : * *: : :. :. . : :
Mb3018|M.bovis_AF2122/97 SWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVF
Rv2994|M.tuberculosis_H37Rv SWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVF
MMAR_1717|M.marinum_M SWGMVVTLVAWGYVLDHVGEQIVMTVGSALTAIAAYAAASVDSLLLMGIY
MAV_3846|M.avium_104 SWGMVVTLVAWGYVLDRVGERVVMTTGSALTALAAYAASSAHSMVLIAVY
Mflv_4231|M.gilvum_PYR-GCK SLGMVVTLIAWGYVVDRIGERAVLTAGSALTAAASFAAASMDTLLTTGIF
Mvan_2131|M.vanbaalenii_PYR-1 SLGMVVTLIAWGYVVDRVGERVVLTLGSALTAAAAFAAAAADTLLTTGVF
MSMEG_2380|M.smegmatis_MC2_155 SFGMVTTLIAWGYVVDRFGERLVLGLGSALTAAAALAAASVQSLFAVGLF
TH_2039|M.thermoresistible__bu SFGMVATLIAWGYLVDRIGERIVLTVGSALTAASAFAAAAVDSLLLVGVF
MAB_3302|M.abscessus_ATCC_1997 SFGMVLTLIAWGALIDKFGERIALVSGLALTAVAAFAAAESPSLTVTGAF
MUL_0354|M.ulcerans_Agy99 GVGWAVGQLVCGWLVDSLGPRATLAWTMTIAAGVLVGMAEARSVAALLVG
. * . .. * ::* .* : .: :::* . : ::
Mb3018|M.bovis_AF2122/97 LFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQT--AQPLGIASGAL
Rv2994|M.tuberculosis_H37Rv LFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQT--AQPLGIASGAL
MMAR_1717|M.marinum_M LFLGGMAAASCNSAGGRLVSGWFPPHQRGLAMGIRQT--AQPLGIALGAL
MAV_3846|M.avium_104 LFLGGMAAASCNTAGGRLVSAWFPPHQRGLAMGIRQT--AQPLGIALGAM
Mflv_4231|M.gilvum_PYR-GCK LFLGGMAAASSNTASARLVVGWFDAERRGLVMGIRQT--AQPLGVGVGAL
Mvan_2131|M.vanbaalenii_PYR-1 LFLGGMAAASSNTASGRLVVGWFDAERRGLVMGIRQT--AQPLGVGVGAL
MSMEG_2380|M.smegmatis_MC2_155 LLLGGMAAASSNSASGRLVVGWFPPEQRGLVMGIRQT--ATPLGVGLGAL
TH_2039|M.thermoresistible__bu LLLGGMAAASSNTASARVVVGWFPPHQRGLVMGIRQT--AQPLGVALGAL
MAB_3302|M.abscessus_ATCC_1997 LLLGGAAAAACNSASGRVVVGWFPPHQRGTVMGIRQM--AQPLGVAAGAL
MUL_0354|M.ulcerans_Agy99 AMITGVVYDAPRPVMGAAIAELIPEPSRRAKLDAWRFGWIVSIGRAITGG
:: * . . ... . : : * :. : .:* . .
Mb3018|M.bovis_AF2122/97 VIPELAE-RGVHAGLMFPAVVCTLAAVASVLGIVD----PPRKSRTKASE
Rv2994|M.tuberculosis_H37Rv VIPELAE-RGVHAGLMFPAVVCTLAAVASVLGIVD----PPRKSRTKASE
MMAR_1717|M.marinum_M VIPELAE-HSIHNALMFPAAFCTIAAVASLVGVVD----PPRKSRKVASK
MAV_3846|M.avium_104 VIPELAE-HGPQAGLRFTALACVFGAVASVIGIVD----PPRKPRASASD
Mflv_4231|M.gilvum_PYR-GCK VIPRLAESHGLSAALLFPAVVCAVSAVLCLAAVID----PPRPARADAAR
Mvan_2131|M.vanbaalenii_PYR-1 VIPRLAQAEGVSAALLFPAIVCAAAAVLCAIAVVD----PPRPARAEADD
MSMEG_2380|M.smegmatis_MC2_155 VIPRLAESHGVSAALLFPAVVCGIAAVVSAVFVLD----PPRPPRAEAPA
TH_2039|M.thermoresistible__bu VIPRLAQSHGISAALLFPAAVCAVAAVICLIGVLD----PPRPPRASADG
MAB_3302|M.abscessus_ATCC_1997 VIPRIAEGHGVATALLFPAIVCAVSSAVCLVGIID----PPRPPRSEAPE
MUL_0354|M.ulcerans_Agy99 VGGLLAAWSGVPVLFWINAVACALLALVAARCIPATAHRPPVAPAVHVRA
* :* . : : * * : . : ** . .
Mb3018|M.bovis_AF2122/97 QELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAG
Rv2994|M.tuberculosis_H37Rv QELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAG
MMAR_1717|M.marinum_M EELASPYRGSAVLWRIHASSALLMMPQTVTVTFMLVWLMNHHGWPVATAG
MAV_3846|M.avium_104 QELASPYRGSLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRNLHWSVAAAG
Mflv_4231|M.gilvum_PYR-GCK TDLANPYRNSAMLWRIHLTSVLLVIPQVVVWTFTLVWMISEHGWSPESAG
Mvan_2131|M.vanbaalenii_PYR-1 TDLANPYRGSPMLWRIHLTSVLLVVPQVMVWTFTLVWLISEHRWSPESAG
MSMEG_2380|M.smegmatis_MC2_155 EHLANPYRGSSVLWRIHAVSVLLVVPQGVLWTFALVWLITDRGWSAASAG
TH_2039|M.thermoresistible__bu RHPQNPYRGSGLLWRIHAVSVLLVVPQGVIWTFTLVWLMTERSWSAGSAG
MAB_3302|M.abscessus_ATCC_1997 EHLANPYRGSRVLWLIHGVSVLLVVPQVVVWTFTLVWLVTDRGWSIGAAS
MUL_0354|M.ulcerans_Agy99 AHNSYRRAFSDGRLVLLFASSLATLTAVRGLYATVPMLMADSGLGAGEFG
. * : : * :. : :: . .
Mb3018|M.bovis_AF2122/97 VLVTISQLLGALGRVAVGRWS--------DHVGSRMRP-VRLIAAAAAAT
Rv2994|M.tuberculosis_H37Rv VLVTISQLLGALGRVAVGRWS--------DHVGSRMRP-VRLIAAAAAAT
MMAR_1717|M.marinum_M ILVTVSQLLGALGRIAVGRWS--------DRVGSRMRP-VRVIAIASAAA
MAV_3846|M.avium_104 ALVTLSQLLGALGRVAVGRWS--------DRLGSRMRP-VRYIAAAAVLV
Mflv_4231|M.gilvum_PYR-GCK VLVMVAQIMGAAGRIGAGRWSDHYVRRSGDLLASRLRP-IRIIAAAAAAS
Mvan_2131|M.vanbaalenii_PYR-1 LLVMTAQILGAAGRIGAGRWSDTFVRRSGDVIASRLRP-IRMIAAAAAAA
MSMEG_2380|M.smegmatis_MC2_155 ILVTVTQLLGAGGRIAAGKWS--------DVIGYRLRP-IRTIALAAAVT
TH_2039|M.thermoresistible__bu TMVMIAQVLGAGGRVAAGRWS--------DLVGSRLRP-IRTIALAAAAA
MAB_3302|M.abscessus_ATCC_1997 VMVTVAQLVGALGRVAAGMWS--------DRWGSRMRP-IRAIAAAASAT
MUL_0354|M.ulcerans_Agy99 WAQVANAAAGIGLTPVITPWLG-------RKVAARINPRLDILAIAGGWT
* * . *:.* : :* *.
Mb3018|M.bovis_AF2122/97 LFLLAAVDNEGSRYDVLLMIAISVI-AVLDNGLEATAITEYAGPYWSGRA
Rv2994|M.tuberculosis_H37Rv LFLLAAVDNEGSRYDVLLMIAISVI-AVLDNGLEATAITEYAGPYWSGRA
MMAR_1717|M.marinum_M LFLLALVDDEGSRYDVLLMITITVI-AVLDNGLQATAITEYAGPYWSGRA
MAV_3846|M.avium_104 LLLLAWADYLNSRWQAGLMVAISVI-AVLDNGLEATAITEFAGPYWSGRA
Mflv_4231|M.gilvum_PYR-GCK MALLALTDLVNSPLSIALMMVASVI-TVSDNGLAFTLIAEYAGPFWSGRA
Mvan_2131|M.vanbaalenii_PYR-1 MALLAVTDWLDSPVSIVVMIAASVI-TVSDNGLAFTLIAEYAGPFWSGRA
MSMEG_2380|M.smegmatis_MC2_155 MAALALTDWLSSPVSIALMVAASVI-TVSDNGLAFTGIAEIAGPFWSGRA
TH_2039|M.thermoresistible__bu MALLALTDALDSPVSVAFMVIAAVV-TVSDNSLAFTAIAEIAGPYWTGRA
MAB_3302|M.abscessus_ATCC_1997 MALLAVTNQLDWSVSVVVMLVASVI-TVSDNGLAYTSIAEIAGPFWSGRA
MUL_0354|M.ulcerans_Agy99 ALTMAGAALAHTTFGFAIAVAASAAGEIAWFVIAVGTVHRIAPPASGGRY
:* . . : :. : : : . * * **
Mb3018|M.bovis_AF2122/97 LGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRL
Rv2994|M.tuberculosis_H37Rv LGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRL
MMAR_1717|M.marinum_M LGVQNTTQRLMAAAGPPIFGALITTAAYPLAWGLCGLFPLAAIPLVPTRL
MAV_3846|M.avium_104 LGIQNTTQRMMAAAGPPLFGALISAAKYPPAWLLCALFPLAAMPLVPTRL
Mflv_4231|M.gilvum_PYR-GCK LGTQNTSQLFAQGVAPPLFGGLIAVAGYPVAFAVCALLPVLAIPAVPLKV
Mvan_2131|M.vanbaalenii_PYR-1 LGTQNTSQLFAQGVAPPLFGGLIAIAGYPVAFAVCALFPLLAIPSVPLTV
MSMEG_2380|M.smegmatis_MC2_155 LGTQNTSQHLATAVSSPVFGGLIGVAGYPVAFAVCALLPALAIPLVPVEP
TH_2039|M.thermoresistible__bu LGTQNTSQLLTTAITPPLFGGLIGVAGYPVAFALCAVLPLAAVPLVPADP
MAB_3302|M.abscessus_ATCC_1997 LGAQNTGQLLAAAVAPPIFGAIAAAAGFSAAFAVCALFPLAAVGLVPVKL
MUL_0354|M.ulcerans_Agy99 HGIWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALCLPLN
* . : . : . . . . : . .
Mb3018|M.bovis_AF2122/97 LPPGLETRARRQSVRRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTA
Rv2994|M.tuberculosis_H37Rv LPPGLETRARRQSVRRHRWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTA
MMAR_1717|M.marinum_M RPPGLEPRERPQSARRLRRWQAVRSRELPSNPRPPDPPG-----------
MAV_3846|M.avium_104 LPPGLETRARRQSVRRLRWWRAVRSHALPDIVRRPGQPG-----------
Mflv_4231|M.gilvum_PYR-GCK TVDR----------------------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 KPDR----------------------------------------------
MSMEG_2380|M.smegmatis_MC2_155 ARES----------------------------------------------
TH_2039|M.thermoresistible__bu ATPQIRPSSPESPRRVR---------------------------------
MAB_3302|M.abscessus_ATCC_1997 ERPAP---------------------------------------------
MUL_0354|M.ulcerans_Agy99 RSGDVGVRDSQYTAVAAAA-------------------------------
Mb3018|M.bovis_AF2122/97 ITPPT
Rv2994|M.tuberculosis_H37Rv ITPPT
MMAR_1717|M.marinum_M -----
MAV_3846|M.avium_104 -----
Mflv_4231|M.gilvum_PYR-GCK -----
Mvan_2131|M.vanbaalenii_PYR-1 -----
MSMEG_2380|M.smegmatis_MC2_155 -----
TH_2039|M.thermoresistible__bu -----
MAB_3302|M.abscessus_ATCC_1997 -----
MUL_0354|M.ulcerans_Agy99 -----