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MVTMVHVDEVGTARRWAMLAIALGSTAGANVFINGVAFLIPALHAERGLDLANAGLLSAMPSFGMVLTLI AWGALIDKFGERIALVSGLALTAVAAFAAAESPSLTVTGAFLLLGGAAAAACNSASGRVVVGWFPPHQRG TVMGIRQMAQPLGVAAGALVIPRIAEGHGVATALLFPAIVCAVSSAVCLVGIIDPPRPPRSEAPEEHLAN PYRGSRVLWLIHGVSVLLVVPQVVVWTFTLVWLVTDRGWSIGAASVMVTVAQLVGALGRVAAGMWSDRWG SRMRPIRAIAAAASATMALLAVTNQLDWSVSVVVMLVASVITVSDNGLAYTSIAEIAGPFWSGRALGAQN TGQLLAAAVAPPIFGAIAAAAGFSAAFAVCALFPLAAVGLVPVKLERPAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3302 | - | - | 100% (400) | major facilitator transporter |
| M. abscessus ATCC 19977 | MAB_3449c | - | 7e-12 | 23.60% (394) | putative transporter |
| M. abscessus ATCC 19977 | MAB_2706c | - | 3e-11 | 27.64% (322) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3018 | - | 1e-127 | 56.78% (391) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4231 | - | 1e-142 | 62.94% (394) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2994 | - | 1e-127 | 56.78% (391) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1717 | - | 1e-124 | 55.64% (390) | integral membrane transport protein |
| M. avium 104 | MAV_3846 | - | 1e-122 | 53.81% (394) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_2380 | - | 1e-152 | 68.81% (388) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_2039 | - | 1e-150 | 66.07% (392) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4170 | - | 3e-07 | 23.02% (417) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_2131 | - | 1e-142 | 63.80% (395) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3018|M.bovis_AF2122/97 -----------------------------MSRDPTG-----VGARWAIMI
Rv2994|M.tuberculosis_H37Rv -----------------------------MSRDPTG-----VGARWAIMI
MMAR_1717|M.marinum_M -----------------------------MPDESSATQELSLSARWWIVI
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
Mflv_4231|M.gilvum_PYR-GCK ----------------------------------MAPSSIGPTRRWLMLA
Mvan_2131|M.vanbaalenii_PYR-1 --------------MSHIMRIWFSIVRRLCNHGAMPATAISSMRRWSMLA
MSMEG_2380|M.smegmatis_MC2_155 ------------------MELRFDILRSRDSMERMAAPVIGTLRRWSMLV
TH_2039|M.thermoresistible__bu ----------------------------------MPVSSISPARRWSMLV
MAB_3302|M.abscessus_ATCC_1997 ------------------------------MVTMVHVDEVGTARRWAMLA
MUL_4170|M.ulcerans_Agy99 -------------------------------------MNRGNVRPKLVLG
::
Mb3018|M.bovis_AF2122/97 VSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMF
Rv2994|M.tuberculosis_H37Rv VSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMF
MMAR_1717|M.marinum_M VSLIVTASSFLFINGVAFLIPRLENARDTPLAEAGLLASMPSWGMVVTLV
MAV_3846|M.avium_104 VSLLATASSFLFINGVAFLIPSLQGARGIRLDEAGLLASMPSWGMVVTLV
Mflv_4231|M.gilvum_PYR-GCK IGLLTTLCANVFINGVAFLIPTLHDERGLDLAGAALMSSLPSLGMVVTLI
Mvan_2131|M.vanbaalenii_PYR-1 IGLLATLCANVFINGVAFLIPTLHDERGLDLAAAGLMSSLPSLGMVVTLI
MSMEG_2380|M.smegmatis_MC2_155 IALTSTMCANVFINGAAFLIPTLHAERGLDLARSGLLSSMPSFGMVTTLI
TH_2039|M.thermoresistible__bu IALAATLFSVVFINGVAFVIPTLHREHGLSLAQAGLLSALPSFGMVATLI
MAB_3302|M.abscessus_ATCC_1997 IALGSTAGANVFINGVAFLIPALHAERGLDLANAGLLSAMPSFGMVLTLI
MUL_4170|M.ulcerans_Agy99 VIVLGSFIASIDLTIVNVALPTLSRALQASNAELQWIVDSYAIAAAGLLL
: : : : : :. . . :* * : : . . :.
Mb3018|M.bovis_AF2122/97 AWGYLLDHVGERMVMAVGSALT-AAAAYAAASVHSLLWIGVFLFLGGMAA
Rv2994|M.tuberculosis_H37Rv AWGYLLDHVGERMVMAVGSALT-AAAAYAAASVHSLLWIGVFLFLGGMAA
MMAR_1717|M.marinum_M AWGYVLDHVGEQIVMTVGSALT-AIAAYAAASVDSLLLMGIYLFLGGMAA
MAV_3846|M.avium_104 AWGYVLDRVGERVVMTTGSALT-ALAAYAASSAHSMVLIAVYLFLGGMAA
Mflv_4231|M.gilvum_PYR-GCK AWGYVVDRIGERAVLTAGSALT-AAASFAAASMDTLLTTGIFLFLGGMAA
Mvan_2131|M.vanbaalenii_PYR-1 AWGYVVDRVGERVVLTLGSALT-AAAAFAAAAADTLLTTGVFLFLGGMAA
MSMEG_2380|M.smegmatis_MC2_155 AWGYVVDRFGERLVLGLGSALT-AAAALAAASVQSLFAVGLFLLLGGMAA
TH_2039|M.thermoresistible__bu AWGYLVDRIGERIVLTVGSALT-AASAFAAAAVDSLLLVGVFLLLGGMAA
MAB_3302|M.abscessus_ATCC_1997 AWGALIDKFGERIALVSGLALT-AVAAFAAAESPSLTVTGAFLLLGGAAA
MUL_4170|M.ulcerans_Agy99 AAGNLGDRYGRRGWLTIGLVIVGASSAVAASAGSAQAVIGARAVMGVGAA
* * : *: *.: : * .:. * :: **: : . .:* **
Mb3018|M.bovis_AF2122/97 GGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAE-RG
Rv2994|M.tuberculosis_H37Rv GGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAE-RG
MMAR_1717|M.marinum_M ASCNSAGGRLVSGWFPPHQRGLAMGIRQTAQPLGIALGALVIPELAE-HS
MAV_3846|M.avium_104 ASCNTAGGRLVSAWFPPHQRGLAMGIRQTAQPLGIALGAMVIPELAE-HG
Mflv_4231|M.gilvum_PYR-GCK ASSNTASARLVVGWFDAERRGLVMGIRQTAQPLGVGVGALVIPRLAESHG
Mvan_2131|M.vanbaalenii_PYR-1 ASSNTASGRLVVGWFDAERRGLVMGIRQTAQPLGVGVGALVIPRLAQAEG
MSMEG_2380|M.smegmatis_MC2_155 ASSNSASGRLVVGWFPPEQRGLVMGIRQTATPLGVGLGALVIPRLAESHG
TH_2039|M.thermoresistible__bu ASSNTASARVVVGWFPPHQRGLVMGIRQTAQPLGVALGALVIPRLAQSHG
MAB_3302|M.abscessus_ATCC_1997 AACNSASGRVVVGWFPPHQRGTVMGIRQMAQPLGVAAGALVIPRIAEGHG
MUL_4170|M.ulcerans_Agy99 IIFPTSLALVTNVFVDSTHRARAIGVWSAVTGIAVVIGPILGGWLIEHFS
:: . :. :. . :*. .:*: . . :.: *.:: : : .
Mb3018|M.bovis_AF2122/97 VHAGLMFPAVVCTLAAVASVLGIVDPPRKSRT------------------
Rv2994|M.tuberculosis_H37Rv VHAGLMFPAVVCTLAAVASVLGIVDPPRKSRT------------------
MMAR_1717|M.marinum_M IHNALMFPAAFCTIAAVASLVGVVDPPRKSRK------------------
MAV_3846|M.avium_104 PQAGLRFTALACVFGAVASVIGIVDPPRKPRA------------------
Mflv_4231|M.gilvum_PYR-GCK LSAALLFPAVVCAVSAVLCLAAVIDPPRPARA------------------
Mvan_2131|M.vanbaalenii_PYR-1 VSAALLFPAIVCAAAAVLCAIAVVDPPRPARA------------------
MSMEG_2380|M.smegmatis_MC2_155 VSAALLFPAVVCGIAAVVSAVFVLDPPRPPRA------------------
TH_2039|M.thermoresistible__bu ISAALLFPAAVCAVAAVICLIGVLDPPRPPRA------------------
MAB_3302|M.abscessus_ATCC_1997 VATALLFPAIVCAVSSAVCLVGIIDPPRPPRS------------------
MUL_4170|M.ulcerans_Agy99 VGSVFWVNVPIAVVAIVSVNMFVPTSRNPDRPPLDLPGLLVSTVGVTVLT
: . . . . . : . . *
Mb3018|M.bovis_AF2122/97 ----KASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHH
Rv2994|M.tuberculosis_H37Rv ----KASEQELASPYRGSSILWRIHAASALLMMPQTVTVTFMLVWLINHH
MMAR_1717|M.marinum_M ----VASKEELASPYRGSAVLWRIHASSALLMMPQTVTVTFMLVWLMNHH
MAV_3846|M.avium_104 ----SASDQELASPYRGSLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRNL
Mflv_4231|M.gilvum_PYR-GCK ----DAARTDLANPYRNSAMLWRIHLTSVLLVIPQVVVWTFTLVWMISEH
Mvan_2131|M.vanbaalenii_PYR-1 ----EADDTDLANPYRGSPMLWRIHLTSVLLVVPQVMVWTFTLVWLISEH
MSMEG_2380|M.smegmatis_MC2_155 ----EAPAEHLANPYRGSSVLWRIHAVSVLLVVPQGVLWTFALVWLITDR
TH_2039|M.thermoresistible__bu ----SADGRHPQNPYRGSGLLWRIHAVSVLLVVPQGVIWTFTLVWLMTER
MAB_3302|M.abscessus_ATCC_1997 ----EAPEEHLANPYRGSRVLWLIHGVSVLLVVPQVVVWTFTLVWLVTDR
MUL_4170|M.ulcerans_Agy99 YTLIETPNIGWASARTAAGFALAVVLLAVFLWLERRTWHPILDLSIFANR
: .. : : : :: : : .: : :. .
Mb3018|M.bovis_AF2122/97 GWSVAQAGVLVTISQLLGALGRVAVGRWS--------DHVGSRMRPVRLI
Rv2994|M.tuberculosis_H37Rv GWSVAQAGVLVTISQLLGALGRVAVGRWS--------DHVGSRMRPVRLI
MMAR_1717|M.marinum_M GWPVATAGILVTVSQLLGALGRIAVGRWS--------DRVGSRMRPVRVI
MAV_3846|M.avium_104 HWSVAAAGALVTLSQLLGALGRVAVGRWS--------DRLGSRMRPVRYI
Mflv_4231|M.gilvum_PYR-GCK GWSPESAGVLVMVAQIMGAAGRIGAGRWSDHYVRRSGDLLASRLRPIRII
Mvan_2131|M.vanbaalenii_PYR-1 RWSPESAGLLVMTAQILGAAGRIGAGRWSDTFVRRSGDVIASRLRPIRMI
MSMEG_2380|M.smegmatis_MC2_155 GWSAASAGILVTVTQLLGAGGRIAAGKWS--------DVIGYRLRPIRTI
TH_2039|M.thermoresistible__bu SWSAGSAGTMVMIAQVLGAGGRVAAGRWS--------DLVGSRLRPIRTI
MAB_3302|M.abscessus_ATCC_1997 GWSIGAASVMVTVAQLVGALGRVAAGMWS--------DRWGSRMRPIRAI
MUL_4170|M.ulcerans_Agy99 RFSGGTA--AVTTAYLVMCGFIFVATQYLQFVAAYRAFDTGVRLVPLAFS
:. * * : :: . . . : . *: *:
Mb3018|M.bovis_AF2122/97 AAAAAATLFLLAAVDNEGSRYDVLLMIAISVIAVL---DNGLEATAITEY
Rv2994|M.tuberculosis_H37Rv AAAAAATLFLLAAVDNEGSRYDVLLMIAISVIAVL---DNGLEATAITEY
MMAR_1717|M.marinum_M AIASAAALFLLALVDDEGSRYDVLLMITITVIAVL---DNGLQATAITEY
MAV_3846|M.avium_104 AAAAVLVLLLLAWADYLNSRWQAGLMVAISVIAVL---DNGLEATAITEF
Mflv_4231|M.gilvum_PYR-GCK AAAAAASMALLALTDLVNSPLSIALMMVASVITVS---DNGLAFTLIAEY
Mvan_2131|M.vanbaalenii_PYR-1 AAAAAAAMALLAVTDWLDSPVSIVVMIAASVITVS---DNGLAFTLIAEY
MSMEG_2380|M.smegmatis_MC2_155 ALAAAVTMAALALTDWLSSPVSIALMVAASVITVS---DNGLAFTGIAEI
TH_2039|M.thermoresistible__bu ALAAAAAMALLALTDALDSPVSVAFMVIAAVVTVS---DNSLAFTAIAEI
MAB_3302|M.abscessus_ATCC_1997 AAAASATMALLAVTNQLDWSVSVVVMLVASVITVS---DNGLAYTSIAEI
MUL_4170|M.ulcerans_Agy99 YAGLSVIAPRIVERVGTTAVVTSGLVMVAVSVACAGGFDAGTPYWLIAAV
. :. .:: :: * . *:
Mb3018|M.bovis_AF2122/97 AGPYWSGRALGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCG-----
Rv2994|M.tuberculosis_H37Rv AGPYWSGRALGIQNTTQRLMAAAGPPLFGSLITTAAYPTAWALCG-----
MMAR_1717|M.marinum_M AGPYWSGRALGVQNTTQRLMAAAGPPIFGALITTAAYPLAWGLCG-----
MAV_3846|M.avium_104 AGPYWSGRALGIQNTTQRMMAAAGPPLFGALISAAKYPPAWLLCA-----
Mflv_4231|M.gilvum_PYR-GCK AGPFWSGRALGTQNTSQLFAQGVAPPLFGGLIAVAGYPVAFAVCA-----
Mvan_2131|M.vanbaalenii_PYR-1 AGPFWSGRALGTQNTSQLFAQGVAPPLFGGLIAIAGYPVAFAVCA-----
MSMEG_2380|M.smegmatis_MC2_155 AGPFWSGRALGTQNTSQHLATAVSSPVFGGLIGVAGYPVAFAVCA-----
TH_2039|M.thermoresistible__bu AGPYWTGRALGTQNTSQLLTTAITPPLFGGLIGVAGYPVAFALCA-----
MAB_3302|M.abscessus_ATCC_1997 AGPFWSGRALGAQNTGQLLAAAVAPPIFGAIAAAAGFSAAFAVCA-----
MUL_4170|M.ulcerans_Agy99 MAALGSGLGLTMAPASEAIMGSLSPTAAGVGSAVTGVARQLGACLGVAIV
.. :* .* : : : . .. * : . *
Mb3018|M.bovis_AF2122/97 --VFPLAAVPLVPVRLLPPGLETRARRQSVRRHRWWQAVRCHAWPNGPRR
Rv2994|M.tuberculosis_H37Rv --VFPLAAVPLVPVRLLPPGLETRARRQSVRRHRWWQAVRCHAWPNGPRR
MMAR_1717|M.marinum_M --LFPLAAIPLVPTRLRPPGLEPRERPQSARRLRRWQAVRSRELPSNPRP
MAV_3846|M.avium_104 --LFPLAAMPLVPTRLLPPGLETRARRQSVRRLRWWRAVRSHALPDIVRR
Mflv_4231|M.gilvum_PYR-GCK --LLPVLAIPAVPLKVTVDR------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 --LFPLLAIPSVPLTVKPDR------------------------------
MSMEG_2380|M.smegmatis_MC2_155 --LLPALAIPLVPVEPARES------------------------------
TH_2039|M.thermoresistible__bu --VLPLAAVPLVPADPATPQIRPSSPESPRRVR-----------------
MAB_3302|M.abscessus_ATCC_1997 --LFPLAAVGLVPVKLERPAP-----------------------------
MUL_4170|M.ulcerans_Agy99 GSVFASVYLRSMSSNAALHGLDPAARAAMRQSMAAAKQVLDQLPVGEAPA
::. : :.
Mb3018|M.bovis_AF2122/97 PGPPGQPRRVRQGGTAITPPT-----------------------------
Rv2994|M.tuberculosis_H37Rv PGPPGQPRRVRQGGTAITPPT-----------------------------
MMAR_1717|M.marinum_M PDPPG---------------------------------------------
MAV_3846|M.avium_104 PGQPG---------------------------------------------
Mflv_4231|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2380|M.smegmatis_MC2_155 --------------------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------------------
MAB_3302|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4170|M.ulcerans_Agy99 IRHAVESAFLESFGVGCLACAVFAAVGAVVVAFLLPARGEVRDDVAVSVA
Mb3018|M.bovis_AF2122/97 -----------
Rv2994|M.tuberculosis_H37Rv -----------
MMAR_1717|M.marinum_M -----------
MAV_3846|M.avium_104 -----------
Mflv_4231|M.gilvum_PYR-GCK -----------
Mvan_2131|M.vanbaalenii_PYR-1 -----------
MSMEG_2380|M.smegmatis_MC2_155 -----------
TH_2039|M.thermoresistible__bu -----------
MAB_3302|M.abscessus_ATCC_1997 -----------
MUL_4170|M.ulcerans_Agy99 ASAIGPAEGGK