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MSRDPTGVGARWAIMIVSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMFAWGY LLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMG IRQTAQPLGIASGALVIPELAERGVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGS SILWRIHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGALGRVAVGRWSDHVGSRMRP VRLIAAAAAATLFLLAAVDNEGSRYDVLLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRL MAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSVRRHRWWQAVRCHAWPN GPRRPGPPGQPRRVRQGGTAITPPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2994 | - | - | 100% (445) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv1737c | narK2 | 3e-05 | 22.86% (280) | nitrate/nitrite transporter NarK2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3018 | - | 0.0 | 100.00% (445) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_4231 | - | 1e-123 | 54.41% (397) | major facilitator transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3302 | - | 1e-127 | 56.78% (391) | major facilitator transporter |
| M. marinum M | MMAR_1717 | - | 0.0 | 80.57% (422) | integral membrane transport protein |
| M. avium 104 | MAV_3846 | - | 0.0 | 74.88% (434) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_2380 | - | 1e-129 | 58.87% (389) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_2039 | - | 1e-128 | 54.69% (426) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2131 | - | 1e-125 | 56.78% (391) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4231|M.gilvum_PYR-GCK ----------------------------------MAPSSIGPTRRWLMLA
Mvan_2131|M.vanbaalenii_PYR-1 --------------MSHIMRIWFSIVRRLCNHGAMPATAISSMRRWSMLA
MSMEG_2380|M.smegmatis_MC2_155 ------------------MELRFDILRSRDSMERMAAPVIGTLRRWSMLV
TH_2039|M.thermoresistible__bu ----------------------------------MPVSSISPARRWSMLV
MAB_3302|M.abscessus_ATCC_1997 ------------------------------MVTMVHVDEVGTARRWAMLA
Rv2994|M.tuberculosis_H37Rv -----------------------------MSRDPTG-----VGARWAIMI
Mb3018|M.bovis_AF2122/97 -----------------------------MSRDPTG-----VGARWAIMI
MMAR_1717|M.marinum_M -----------------------------MPDESSATQELSLSARWWIVI
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
** ::
Mflv_4231|M.gilvum_PYR-GCK IGLLTTLCANVFINGVAFLIPTLHDERGLDLAGAALMSSLPSLGMVVTLI
Mvan_2131|M.vanbaalenii_PYR-1 IGLLATLCANVFINGVAFLIPTLHDERGLDLAAAGLMSSLPSLGMVVTLI
MSMEG_2380|M.smegmatis_MC2_155 IALTSTMCANVFINGAAFLIPTLHAERGLDLARSGLLSSMPSFGMVTTLI
TH_2039|M.thermoresistible__bu IALAATLFSVVFINGVAFVIPTLHREHGLSLAQAGLLSALPSFGMVATLI
MAB_3302|M.abscessus_ATCC_1997 IALGSTAGANVFINGVAFLIPALHAERGLDLANAGLLSAMPSFGMVLTLI
Rv2994|M.tuberculosis_H37Rv VSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMF
Mb3018|M.bovis_AF2122/97 VSLGVTASSFLFINGVAFLIPRLENARGTPLSHAGLLASMPSWGLVVTMF
MMAR_1717|M.marinum_M VSLIVTASSFLFINGVAFLIPRLENARDTPLAEAGLLASMPSWGMVVTLV
MAV_3846|M.avium_104 VSLLATASSFLFINGVAFLIPSLQGARGIRLDEAGLLASMPSWGMVVTLV
:.* * : :****.**:** *. :. * :.*::::** *:* *:.
Mflv_4231|M.gilvum_PYR-GCK AWGYVVDRIGERAVLTAGSALTAAASFAAASMDTLLTTGIFLFLGGMAAA
Mvan_2131|M.vanbaalenii_PYR-1 AWGYVVDRVGERVVLTLGSALTAAAAFAAAAADTLLTTGVFLFLGGMAAA
MSMEG_2380|M.smegmatis_MC2_155 AWGYVVDRFGERLVLGLGSALTAAAALAAASVQSLFAVGLFLLLGGMAAA
TH_2039|M.thermoresistible__bu AWGYLVDRIGERIVLTVGSALTAASAFAAAAVDSLLLVGVFLLLGGMAAA
MAB_3302|M.abscessus_ATCC_1997 AWGALIDKFGERIALVSGLALTAVAAFAAAESPSLTVTGAFLLLGGAAAA
Rv2994|M.tuberculosis_H37Rv AWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMAAG
Mb3018|M.bovis_AF2122/97 AWGYLLDHVGERMVMAVGSALTAAAAYAAASVHSLLWIGVFLFLGGMAAG
MMAR_1717|M.marinum_M AWGYVLDHVGEQIVMTVGSALTAIAAYAAASVDSLLLMGIYLFLGGMAAA
MAV_3846|M.avium_104 AWGYVLDRVGERVVMTTGSALTALAAYAASSAHSMVLIAVYLFLGGMAAA
*** ::*:.**: .: * **** :: **: :: . :*:*** **.
Mflv_4231|M.gilvum_PYR-GCK SSNTASARLVVGWFDAERRGLVMGIRQTAQPLGVGVGALVIPRLAESHGL
Mvan_2131|M.vanbaalenii_PYR-1 SSNTASGRLVVGWFDAERRGLVMGIRQTAQPLGVGVGALVIPRLAQAEGV
MSMEG_2380|M.smegmatis_MC2_155 SSNSASGRLVVGWFPPEQRGLVMGIRQTATPLGVGLGALVIPRLAESHGV
TH_2039|M.thermoresistible__bu SSNTASARVVVGWFPPHQRGLVMGIRQTAQPLGVALGALVIPRLAQSHGI
MAB_3302|M.abscessus_ATCC_1997 ACNSASGRVVVGWFPPHQRGTVMGIRQMAQPLGVAAGALVIPRIAEGHGV
Rv2994|M.tuberculosis_H37Rv GCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAE-RGV
Mb3018|M.bovis_AF2122/97 GCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPELAE-RGV
MMAR_1717|M.marinum_M SCNSAGGRLVSGWFPPHQRGLAMGIRQTAQPLGIALGALVIPELAE-HSI
MAV_3846|M.avium_104 SCNTAGGRLVSAWFPPHQRGLAMGIRQTAQPLGIALGAMVIPELAE-HGP
..*:*..*:* .** ..:** .***** * ***:. **:***.:*: ..
Mflv_4231|M.gilvum_PYR-GCK SAALLFPAVVCAVSAVLCLAAVIDPPRPARADAARTDLANPYRNSAMLWR
Mvan_2131|M.vanbaalenii_PYR-1 SAALLFPAIVCAAAAVLCAIAVVDPPRPARAEADDTDLANPYRGSPMLWR
MSMEG_2380|M.smegmatis_MC2_155 SAALLFPAVVCGIAAVVSAVFVLDPPRPPRAEAPAEHLANPYRGSSVLWR
TH_2039|M.thermoresistible__bu SAALLFPAAVCAVAAVICLIGVLDPPRPPRASADGRHPQNPYRGSGLLWR
MAB_3302|M.abscessus_ATCC_1997 ATALLFPAIVCAVSSAVCLVGIIDPPRPPRSEAPEEHLANPYRGSRVLWL
Rv2994|M.tuberculosis_H37Rv HAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWR
Mb3018|M.bovis_AF2122/97 HAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWR
MMAR_1717|M.marinum_M HNALMFPAAFCTIAAVASLVGVVDPPRKSRKVASKEELASPYRGSAVLWR
MAV_3846|M.avium_104 QAGLRFTALACVFGAVASVIGIVDPPRKPRASASDQELASPYRGSLTLWR
.* *.* * .:. . ::**** .* * . .***.* **
Mflv_4231|M.gilvum_PYR-GCK IHLTSVLLVIPQVVVWTFTLVWMISEHGWSPESAGVLVMVAQIMGAAGRI
Mvan_2131|M.vanbaalenii_PYR-1 IHLTSVLLVVPQVMVWTFTLVWLISEHRWSPESAGLLVMTAQILGAAGRI
MSMEG_2380|M.smegmatis_MC2_155 IHAVSVLLVVPQGVLWTFALVWLITDRGWSAASAGILVTVTQLLGAGGRI
TH_2039|M.thermoresistible__bu IHAVSVLLVVPQGVIWTFTLVWLMTERSWSAGSAGTMVMIAQVLGAGGRV
MAB_3302|M.abscessus_ATCC_1997 IHGVSVLLVVPQVVVWTFTLVWLVTDRGWSIGAASVMVTVAQLVGALGRV
Rv2994|M.tuberculosis_H37Rv IHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGALGRV
Mb3018|M.bovis_AF2122/97 IHAASALLMMPQTVTVTFMLVWLINHHGWSVAQAGVLVTISQLLGALGRV
MMAR_1717|M.marinum_M IHASSALLMMPQTVTVTFMLVWLMNHHGWPVATAGILVTVSQLLGALGRI
MAV_3846|M.avium_104 IHAVAGLMMMPQTVTVTFMLVWLIRNLHWSVAAAGALVTLSQLLGALGRV
** : *:::** : ** ***:: . *. *. :* :*::** **:
Mflv_4231|M.gilvum_PYR-GCK GAGRWSDHYVRRSGDLLASRLRPIRIIAAAAAASMALLALTDLVNSPLSI
Mvan_2131|M.vanbaalenii_PYR-1 GAGRWSDTFVRRSGDVIASRLRPIRMIAAAAAAAMALLAVTDWLDSPVSI
MSMEG_2380|M.smegmatis_MC2_155 AAGKWS--------DVIGYRLRPIRTIALAAAVTMAALALTDWLSSPVSI
TH_2039|M.thermoresistible__bu AAGRWS--------DLVGSRLRPIRTIALAAAAAMALLALTDALDSPVSV
MAB_3302|M.abscessus_ATCC_1997 AAGMWS--------DRWGSRMRPIRAIAAAASATMALLAVTNQLDWSVSV
Rv2994|M.tuberculosis_H37Rv AVGRWS--------DHVGSRMRPVRLIAAAAAATLFLLAAVDNEGSRYDV
Mb3018|M.bovis_AF2122/97 AVGRWS--------DHVGSRMRPVRLIAAAAAATLFLLAAVDNEGSRYDV
MMAR_1717|M.marinum_M AVGRWS--------DRVGSRMRPVRVIAIASAAALFLLALVDDEGSRYDV
MAV_3846|M.avium_104 AVGRWS--------DRLGSRMRPVRYIAAAAVLVLLLLAWADYLNSRWQA
..* ** * . *:**:* ** *: : ** .: . .
Mflv_4231|M.gilvum_PYR-GCK ALMMVASVITVSDNGLAFTLIAEYAGPFWSGRALGTQNTSQLFAQGVAPP
Mvan_2131|M.vanbaalenii_PYR-1 VVMIAASVITVSDNGLAFTLIAEYAGPFWSGRALGTQNTSQLFAQGVAPP
MSMEG_2380|M.smegmatis_MC2_155 ALMVAASVITVSDNGLAFTGIAEIAGPFWSGRALGTQNTSQHLATAVSSP
TH_2039|M.thermoresistible__bu AFMVIAAVVTVSDNSLAFTAIAEIAGPYWTGRALGTQNTSQLLTTAITPP
MAB_3302|M.abscessus_ATCC_1997 VVMLVASVITVSDNGLAYTSIAEIAGPFWSGRALGAQNTGQLLAAAVAPP
Rv2994|M.tuberculosis_H37Rv LLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRLMAAAGPP
Mb3018|M.bovis_AF2122/97 LLMIAISVIAVLDNGLEATAITEYAGPYWSGRALGIQNTTQRLMAAAGPP
MMAR_1717|M.marinum_M LLMITITVIAVLDNGLQATAITEYAGPYWSGRALGVQNTTQRLMAAAGPP
MAV_3846|M.avium_104 GLMVAISVIAVLDNGLEATAITEFAGPYWSGRALGIQNTTQRMMAAAGPP
.*: :*::* **.* * *:* ***:*:***** *** * : . .*
Mflv_4231|M.gilvum_PYR-GCK LFGGLIAVAGYPVAFAVCALLPVLAIPAVPLKVTVDR-------------
Mvan_2131|M.vanbaalenii_PYR-1 LFGGLIAIAGYPVAFAVCALFPLLAIPSVPLTVKPDR-------------
MSMEG_2380|M.smegmatis_MC2_155 VFGGLIGVAGYPVAFAVCALLPALAIPLVPVEPARES-------------
TH_2039|M.thermoresistible__bu LFGGLIGVAGYPVAFALCAVLPLAAVPLVPADPATPQIRPSSPESPRRVR
MAB_3302|M.abscessus_ATCC_1997 IFGAIAAAAGFSAAFAVCALFPLAAVGLVPVKLERPAP------------
Rv2994|M.tuberculosis_H37Rv LFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSVRRH
Mb3018|M.bovis_AF2122/97 LFGSLITTAAYPTAWALCGVFPLAAVPLVPVRLLPPGLETRARRQSVRRH
MMAR_1717|M.marinum_M IFGALITTAAYPLAWGLCGLFPLAAIPLVPTRLRPPGLEPRERPQSARRL
MAV_3846|M.avium_104 LFGALISAAKYPPAWLLCALFPLAAMPLVPTRLLPPGLETRARRQSVRRL
:**.: * :. *: :*.::* *: **
Mflv_4231|M.gilvum_PYR-GCK --------------------------------------
Mvan_2131|M.vanbaalenii_PYR-1 --------------------------------------
MSMEG_2380|M.smegmatis_MC2_155 --------------------------------------
TH_2039|M.thermoresistible__bu --------------------------------------
MAB_3302|M.abscessus_ATCC_1997 --------------------------------------
Rv2994|M.tuberculosis_H37Rv RWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT
Mb3018|M.bovis_AF2122/97 RWWQAVRCHAWPNGPRRPGPPGQPRRVRQGGTAITPPT
MMAR_1717|M.marinum_M RRWQAVRSRELPSNPRPPDPPG----------------
MAV_3846|M.avium_104 RWWRAVRSHALPDIVRRPGQPG----------------