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VCSADLTAKARIRNAAVARFARDGFQKVNLRAIATSAGVSEALIFHHFGSKDGLRAACDEYVLNVLVGRA RTAGRPTAMADLLGVYLSNPEEYRLQVQYMARAIEDDAPAAGTFVDTMVEESEAIFRAGAADGSMRPSSD PRALAVLNLLVALGLLTMAPPMARALGHEHFGPEVLQRMAVPALELYTRGLYTDDTLAKAAQDAWVARRA PQQEG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2316 | - | - | 100% (215) | transcriptional regulator |
| M. marinum M | MMAR_4219 | - | 2e-27 | 37.32% (209) | transcriptional regulator |
| M. marinum M | MMAR_2297 | - | 4e-18 | 31.19% (202) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1251c | - | 1e-25 | 35.92% (206) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2198 | - | 6e-27 | 36.89% (206) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1219c | - | 1e-25 | 35.92% (206) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 7e-05 | 37.78% (45) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1360c | - | 8e-24 | 32.66% (199) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1363 | - | 2e-26 | 37.75% (204) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5074 | - | 1e-25 | 36.68% (199) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0547 | - | 8e-25 | 34.88% (215) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1500 | - | 1e-18 | 31.82% (198) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4498 | - | 7e-30 | 39.15% (212) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1251c|M.bovis_AF2122/97 ----MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAALVI
Rv1219c|M.tuberculosis_H37Rv ----MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAALVI
MAV_1363|M.avium_104 -MLNMR-SADLTAAARIRDAAIEQFGEHGFG-VGLRRIAEAAGVSAALVI
MSMEG_5074|M.smegmatis_MC2_155 -------MDDRTAMARIRDTAIEQFGQHGFN-VGLRSIAEAAGVSAALVI
TH_0547|M.thermoresistible__bu ----MRSADDRTAAARIRDAAIDQFGRHGFD-VSVRAIAEAAGVSPALVI
Mflv_2198|M.gilvum_PYR-GCK ----MRSVDDLTAAARIRDAAVELFGAEGFA-VSVRTIAAAAGVSPGLVI
Mvan_4498|M.vanbaalenii_PYR-1 ----MRSADDLTAAARIRDAAIDLFGRDGFA-VGVRSIASAAGVSPGLVI
MAB_1360c|M.abscessus_ATCC_199 ----MRSADDLTAAARIRDAAIKLWGEQGNG-ASVRAIADAAGVSPALVI
MMAR_2316|M.marinum_M -----MCSADLTAKARIRNAAVARFARDGFQKVNLRAIATSAGVSEALIF
MUL_1500|M.ulcerans_Agy99 ---MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPALLI
MLBr_02568|M.leprae_Br4923 MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQISKPMLY
. :: : *: :. * . : ** * :* ::
Mb1251c|M.bovis_AF2122/97 HHFGSKEGLRKACDDFVAEEIR-SSKAAALKSNDPTTWLAQMA-------
Rv1219c|M.tuberculosis_H37Rv HHFGSKEGLRKACDDFVAEEIR-SSKAAALKSNDPTTWLAQMA-------
MAV_1363|M.avium_104 HHFGSKEGLRKACDDHIAEQIR-ESKTEALQTNDPAVWFGQLA-------
MSMEG_5074|M.smegmatis_MC2_155 HHFGSKEGLRKACDDHVAEVIL-ELKTESMHASDPATWLAYVA-------
TH_0547|M.thermoresistible__bu HHFGSKDNLRKACDDHIAEEIR-SGKSAAIRSNDPATWFAQIA-------
Mflv_2198|M.gilvum_PYR-GCK HHFGSKDQLHKACDAYVAETVR-AAKSESIQTSDPATWLAQMA-------
Mvan_4498|M.vanbaalenii_PYR-1 HHFGSKDGLRKACDDFVAETVR-ASKSEAIQSSDPATWLAQIA-------
MAB_1360c|M.abscessus_ATCC_199 HHYGSKDGLRQAVDDYLLAYIR-SEKSRTITSNDPQVWLDAID-------
MMAR_2316|M.marinum_M HHFGSKDGLRAACDEYVLNVLVGRARTAGRPTAMADLLGVYLS-------
MUL_1500|M.ulcerans_Agy99 RHYGSKDGLIEAVDNHVIAIFEVLLTEATRETEAVGLGQAAVGGLLDGLA
MLBr_02568|M.leprae_Br4923 LYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTIVS-----
::***: * * . :
Mb1251c|M.bovis_AF2122/97 -EIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKP
Rv1219c|M.tuberculosis_H37Rv -EIESYAPLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKP
MAV_1363|M.avium_104 -EIEEFAPLIAYVLRSMQTGGDLAKMLWRQMIENAEGYLEEGVRAGTIKP
MSMEG_5074|M.smegmatis_MC2_155 -EIESYAPLMAYLVRSMQSGSELAKKFWRRMVDNAEQYLEEGVRTGMLKP
TH_0547|M.thermoresistible__bu -ELESYAPIMAYLVRSMQSGSDLAKMLWQKMIDDTRWYLDEGERAGTVKP
Mflv_2198|M.gilvum_PYR-GCK -EIEEYAPLMAYLVRSLQAGGELGKMLWRTMTNDVEQYLEDGVRAGTVKP
Mvan_4498|M.vanbaalenii_PYR-1 -EIEEYAPLMAYLVRTLQTGGELAKMLWQNMIDNAEQYIEEGVRAGTVKP
MAB_1360c|M.abscessus_ATCC_199 -EIETFAPMVRYLLHSVQSGGEPGRAFLRRSIDDAEQYLEDGVRAGTIKP
MMAR_2316|M.marinum_M -NPEEYRLQVQYMARAIEDDAPAAGTFVDTMVEESEAIFRAGAADGSMRP
MUL_1500|M.ulcerans_Agy99 THLPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTASP
MLBr_02568|M.leprae_Br4923 FLRYIDANRASWIVMYIQAMSLPA---FAQTVREARDQITELVAGLMRVG
:: : . . . :
Mb1251c|M.bovis_AF2122/97 SRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEV
Rv1219c|M.tuberculosis_H37Rv SRDPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEV
MAV_1363|M.avium_104 SRDPRARAKYLGITGGGGLLLYLQMHDNPTDLRAVLRDYSRDMILPALEI
MSMEG_5074|M.smegmatis_MC2_155 SRDPRARARFLAICGGGGFLLYLQMHDNPTDLRAVLRDYGEDMMLPALEI
TH_0547|M.thermoresistible__bu SRDPKARARFLAISGGGSFLLYLQLHDNPTDLAAVLRDYSRDMMLPALEI
Mflv_2198|M.gilvum_PYR-GCK SADPRARAFFLSMASGGGFLLYLQLHES-TDIRVVLRDYSEAMVLPALEL
Mvan_4498|M.vanbaalenii_PYR-1 SADPRGRARFLAMAGGGGFLLYLQMHDNPTDLRAVLRDYSEEMVLPALEL
MAB_1360c|M.abscessus_ATCC_199 SRDPKGRALWVSLNSVGSLIIYVQMHAN-EDLREILRRYADELIFPAIEV
MMAR_2316|M.marinum_M SSDPRALAVLNLLVALG-LLTMAPPMARALGHEHFGPEVLQRMAVPALEL
MUL_1500|M.ulcerans_Agy99 GADPAVRAAFLLVNDLAVLTLRPRLIEV-LGVDPLTDAGMRRWAGEVFAV
MLBr_02568|M.leprae_Br4923 TRSSRPDHEYEIM--AGALVGAGEAMATRLTTGDIAVDEAAELMINLFWH
.. : . : :
Mb1251c|M.bovis_AF2122/97 YTEGLLADRAMYEAFLAEA-----QQGEAHVG-------
Rv1219c|M.tuberculosis_H37Rv YTEGLLADRAMYEAFLAEA-----QQGEAHVG-------
MAV_1363|M.avium_104 YTEGLMADRTMYDAFLAAE-----DQGDSHGN-------
MSMEG_5074|M.smegmatis_MC2_155 YSHGLMADTTMYETFLHQR-----EAGVPFTGTSEEAT-
TH_0547|M.thermoresistible__bu YTHGLMADSTMFDAFVARETQQLSDQGGAHDDDVAAV--
Mflv_2198|M.gilvum_PYR-GCK YTHGLLTDSTMYDAFVAER-----AHDHSSPSTG-ARDA
Mvan_4498|M.vanbaalenii_PYR-1 YTNGLMTDSTMYDAFVARR-----AQGIPFTSTEGAHDD
MAB_1360c|M.abscessus_ATCC_199 YTEGLMTDSTMLDAFAVQQ-----DKSHSKGDPK-----
MMAR_2316|M.marinum_M YTRGLYTDDTLAKAAQDAW----VARRAPQQEG------
MUL_1500|M.ulcerans_Agy99 YRDGLVSD-------------------------------
MLBr_02568|M.leprae_Br4923 GLKGAPADRDFGPSIVAG---------------------
* :*