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MHPQANGKSLPLSGITVLSLEHAVAAPFATRQLADLGARVIKVERPGSGDFARQYDDSVNGESSYFVWLN RSKESIALDVKSEHGHRVLHELADRADVVVQNLGPGAAARLGLAAEDIRAKDPRKIVVSVTGWGSTGPWA DRKAYDLLVQCETGLVSLTGTPDEVAKVGVSIADIAAGMYAFSGILAALYRREITGEGAVIEVSLFEALA EWVGQPAHFTAGAGRQPGRFGAQHATIAPYGPFEAADGHTLLIAIQNEPEWARFCTTVLGRPEVAEDPRF ASNTQRVANRADVNALISEVFSSHPTDELESRLTEARIAFAGVNTVSEFLDHPVLAARDRWRSVETENGP VRALLPPLDLGTEVRMDPVPALGAHTAAILAELGHGDD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1992 | - | - | 100% (388) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_4834 | - | 3e-89 | 45.83% (384) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_4046 | - | 1e-78 | 42.19% (384) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 6e-43 | 31.71% (391) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2443 | - | 2e-86 | 43.83% (381) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 5e-43 | 31.71% (391) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 1e-51 | 37.38% (321) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 2e-46 | 35.15% (330) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_1892 | - | 1e-122 | 58.58% (379) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_2496 | - | 1e-91 | 44.94% (385) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_4811 | - | 1e-46 | 34.11% (387) | hypothetical protein MUL_4811 |
| M. vanbaalenii PYR-1 | Mvan_4208 | - | 4e-87 | 44.09% (381) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1992|M.smegmatis_MC2_155 MHPQANGKSLPLSGITVLSLEHAVAAPFATRQLADLGARVIKVERPGSGD
MAV_1892|M.avium_104 MG--------PLSGVTVVSLEQAVAAPYATRQLADLGARVIKVERPDGGD
Mflv_2443|M.gilvum_PYR-GCK -MTASQ-SAGPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
Mvan_4208|M.vanbaalenii_PYR-1 -MSSSQPSAAPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
TH_2496|M.thermoresistible__bu MAESEHADPAPLAGITVVALEQAVSAPMCTRVLADFGARVIKVENPDGGD
MAB_0824|M.abscessus_ATCC_1997 ------MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGD
MMAR_1494|M.marinum_M -----MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPD
Mb3300|M.bovis_AF2122/97 --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEA
Rv3272|M.tuberculosis_H37Rv --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEA
MUL_4811|M.ulcerans_Agy99 MGAGAGNRTGPLSGVRVVDLTAMVMGPYCTQIMADMGADVIKIEPPQGDD
.* *. *: : : .* . : *:** :**:* *
MSMEG_1992|M.smegmatis_MC2_155 FARQYDDSVNG---ESSYFVWLNRSKESIALDVKSEHGHRVLHELADRAD
MAV_1892|M.avium_104 FARGYDHSVHG---DSSYFVWLNRGKESLTLDLKTLEGQRILRQLLANSD
Mflv_2443|M.gilvum_PYR-GCK FARAYDDVVNGPGGLAAHFVWSNRGKESVTLNTKSPAGLEVLHRLLDRAD
Mvan_4208|M.vanbaalenii_PYR-1 FARDYDDVVNGPGGLAAHFVWSNRGKESVTLNTKTAGGLDLLHRLLDRAD
TH_2496|M.thermoresistible__bu FARHYDDVVKG---QAAHFVWANRGKESVTLNLKSEAGMAVLHRLLDEAD
MAB_0824|M.abscessus_ATCC_1997 DTRQWGPPYDSDG-QATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRAD
MMAR_1494|M.marinum_M PLRTWG-QAEVDG-HHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSD
Mb3300|M.bovis_AF2122/97 ARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
Rv3272|M.tuberculosis_H37Rv ARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
MUL_4811|M.ulcerans_Agy99 TRYVSVGPAAG---MSGVFVNVNRGKRSAVIDLKSDSGQAAVRALIEGAD
: *.*.: .:: . * :*
MSMEG_1992|M.smegmatis_MC2_155 VVVQNLGPGAAARLGLAAEDIRAKDPRKIVVSVTGWGSTGPWADRKAYDL
MAV_1892|M.avium_104 VLVQNLGPGATTRLSLDATTLTPEYPRLIVCDITGYGGTGPWRDRKAYDL
Mflv_2443|M.gilvum_PYR-GCK AFVSNLAPGATARLGLSPADLAERHPQVIPVEIDGYGPGGPISHKRAYDL
Mvan_4208|M.vanbaalenii_PYR-1 AFVSNLAPGATARLGVAPADLAARHPRVIPVEIDGYGPGGPLSHKRAYDL
TH_2496|M.thermoresistible__bu VLVSNLAPGALARMGLAADDLKTSHPRVLPVQIDGYGAGGPISHKRAYDL
MAB_0824|M.abscessus_ATCC_1997 VVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLPGYDL
MMAR_1494|M.marinum_M IVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYAS
Mb3300|M.bovis_AF2122/97 VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
Rv3272|M.tuberculosis_H37Rv VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
MUL_4811|M.ulcerans_Agy99 VFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRRGPNRDLPAYDD
.: : . : : .: : * : .:* *. .
MSMEG_1992|M.smegmatis_MC2_155 LVQCETGLVSLTGTP-DEVAKVGVSIADIAAGMYAFSGILAALYRREIT-
MAV_1892|M.avium_104 LVQAEAGLLSVTGSG-DEVARTGVSIADIAAGMFAFSGILTALYVRATT-
Mflv_2443|M.gilvum_PYR-GCK LVQAESGSCAVTGYP-GMPAKPGPAVADFTSGLYAAMSIVSLLYGRATR-
Mvan_4208|M.vanbaalenii_PYR-1 LVQAESGSCAVTGYP-GMPAKPGPAVADFSTGLYAAISILALLYGRARH-
TH_2496|M.thermoresistible__bu LIQAESGACAVTGYP-GMPAKPGPPVADISTGLYAALSVMALLYGRDRRD
MAB_0824|M.abscessus_ATCC_1997 LVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRT-
MMAR_1494|M.marinum_M VAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRRSVT-
Mb3300|M.bovis_AF2122/97 VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
Rv3272|M.tuberculosis_H37Rv VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
MUL_4811|M.ulcerans_Agy99 TIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYATMMALFHRERT-
. * : * :. . : * *
MSMEG_1992|M.smegmatis_MC2_155 ----GEGAVIEVSLFEALAEWVGQPAHFTAGAGRQPGRFGAQHAT-----
MAV_1892|M.avium_104 ----GDVRPVSVSLFESLVELVSQPAYYAHYGGTAPPRTGARHAT-----
Mflv_2443|M.gilvum_PYR-GCK -PEPGPAPHVELSLFDVMTDVMGYALTYTQHSGIDQEPLGVGSPA-----
Mvan_4208|M.vanbaalenii_PYR-1 -PGSAPAPSVELSLFDVMTDVMGYALTYTQHSGIDQEPLGVGSPA-----
TH_2496|M.thermoresistible__bu RATPGPVPAVAVSLFDTMTDIMGYQLTYTQHSGVDQQPLGMSSPA-----
MAB_0824|M.abscessus_ATCC_1997 ----GQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEALGNRHPS-----
MMAR_1494|M.marinum_M ----GTGQVVDVALTESCLALQESTISDYDVGGVVRGPSGTRLEG-----
Mb3300|M.bovis_AF2122/97 ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
Rv3272|M.tuberculosis_H37Rv ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
MUL_4811|M.ulcerans_Agy99 ----GQGQEVEIGMFEAVASFMLVEHANGAMFDPPLGPAVYPRTV-----
. : : .
MSMEG_1992|M.smegmatis_MC2_155 -----IAPYGPFEAADGHTLLIAIQNEPEWARFCTTVLGRPEVAEDPRFA
MAV_1892|M.avium_104 -----IAPYGPFTAGDGGTVLLAVQNQREWRRLCDEVLATPGLCEDPRFV
Mflv_2443|M.gilvum_PYR-GCK -----VAPYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
Mvan_4208|M.vanbaalenii_PYR-1 -----VAPYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
TH_2496|M.thermoresistible__bu -----VAPYGAFRTRDGQTVVLGTTNDREWQRLARDIIERPDLADDPAYA
MAB_0824|M.abscessus_ATCC_1997 -----IAPYQTFETADR-PIAIAVGNDKQFRLLVQALE-MPRLARDDRFA
MMAR_1494|M.marinum_M -----IAPSNIYRSADESWVVIAANQDTVFTRLCQAMG-CPELATDDRFA
Mb3300|M.bovis_AF2122/97 GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
Rv3272|M.tuberculosis_H37Rv GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
MUL_4811|M.ulcerans_Agy99 -----APNRRPYRTSDG-YLAALIYNDKHWAAFVDAVR---PPWASEQYA
: : * : : . : . :.
MSMEG_1992|M.smegmatis_MC2_155 SNTQRVANRADVNALISEVFSSHPTDELESRLTEARIAFAGVNTVSEFLD
MAV_1892|M.avium_104 TNPDRVTHRDELEAIIHAAIASMTADELAHRLEAAGIANARMNDVETLWS
Mflv_2443|M.gilvum_PYR-GCK TNPGRCANRDVLEEAIGAWCARHDLAEIQDKADRAGIGNSRYNLPSEVIA
Mvan_4208|M.vanbaalenii_PYR-1 TNSDRCAHRQILEEAIGSWCAQHDLAEIQKTADAAGIGNSRYNLPSEVVV
TH_2496|M.thermoresistible__bu TNSDRVRHRDVLNEAIAAWCARHDLAHIQKTADDAGIGNSRYNLPSEVVA
MAB_0824|M.abscessus_ATCC_1997 TNPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFR
MMAR_1494|M.marinum_M THRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVK
Mb3300|M.bovis_AF2122/97 EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
Rv3272|M.tuberculosis_H37Rv EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
MUL_4811|M.ulcerans_Agy99 TLEGRARQIDTVYALLAETFAARTTQEWLDLLEELEIPASALSSPAELFD
* : : : . :
MSMEG_1992|M.smegmatis_MC2_155 HPVLAARDRWRSVETENGPVRALLP----PLDLG-TEVRMDPVPALGAHT
MAV_1892|M.avium_104 HPVLAGRDRWREVRAPGGAIEALLP----PATLRDVEPQLGDVPGLAAHS
Mflv_2443|M.gilvum_PYR-GCK HPHLVARDRWRTVATPKGDIQALRP----PPVISDFEQPMGAIPGLGEHT
Mvan_4208|M.vanbaalenii_PYR-1 HPHLAARDRWRTVATPKGDIQALRP----PPVISDFEQPMGAIPGLGEHT
TH_2496|M.thermoresistible__bu HPHLSARDRWRPVDTPNGQITALRP----PPVIEGFEQPMGPVPGLGQHT
MAB_0824|M.abscessus_ATCC_1997 FAERLGLDVAVTVPGSPE-PQVANP---ISMSKTP-VVYRNGPPRLGQSR
MMAR_1494|M.marinum_M DRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHN
Mb3300|M.bovis_AF2122/97 TPLFAESDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEHN
Rv3272|M.tuberculosis_H37Rv TPLFAENDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEHN
MUL_4811|M.ulcerans_Agy99 NQHLNAVGFFETIDTAHGPVRFPGVP---TWFSRTPGRVLGPAPQLGADT
. . . .
MSMEG_1992|M.smegmatis_MC2_155 AAILA-ELGHGDD-----------------
MAV_1892|M.avium_104 RMILR-ELGYTNEAIADLVRSGVTTVASDH
Mflv_2443|M.gilvum_PYR-GCK DAVLT-EFGVSAEELAQLRAEGAIGPAYRG
Mvan_4208|M.vanbaalenii_PYR-1 DAVLT-EIGVTPDELRQLRADGAIGPAYRG
TH_2496|M.thermoresistible__bu DAVLSGLLGMTDDEIAALREQGAIGPAYN-
MAB_0824|M.abscessus_ATCC_1997 A-----------------------------
MMAR_1494|M.marinum_M DDVYIGLLGKSIEELEQLRAEEVL------
Mb3300|M.bovis_AF2122/97 AVFLARP-----------------------
Rv3272|M.tuberculosis_H37Rv AVFLARP-----------------------
MUL_4811|M.ulcerans_Agy99 SAVLEELGINAADAQPAGPA----------