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VTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDTRQWGPPYDSDGQATYFNSVNRNKQ SVVLDLTSPDGQHRARELAGRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGRGAGADLPGY DLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRTGQGQRVDTDLMSVLLSSLV NQASGYLGAGVVPEALGNRHPSIAPYQTFETADRPIAIAVGNDKQFRLLVQALEMPRLARDDRFATNPLR VRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFRFAERLGLDVAVTVPGSPEPQVANPI SMSKTPVVYRNGPPRLGQSRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0824 | - | - | 100% (371) | putative L-carnitine dehydratase |
| M. abscessus ATCC 19977 | MAB_4651c | - | 7e-54 | 36.32% (380) | putative L-carnitine dehydratase |
| M. abscessus ATCC 19977 | MAB_0845 | - | 7e-21 | 25.47% (373) | fatty-acid-CoA racemase Far |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 4e-40 | 35.87% (329) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 3e-54 | 37.65% (324) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv3272 | - | 3e-40 | 33.16% (389) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1494 | - | 3e-58 | 39.32% (323) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_4024 | - | 5e-54 | 37.20% (336) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_6689 | - | 1e-151 | 71.04% (366) | CAIB/BAIF family protein |
| M. thermoresistible (build 8) | TH_3339 | - | 2e-60 | 40.57% (318) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_2446 | - | 4e-58 | 39.32% (323) | hypothetical protein MUL_2446 |
| M. vanbaalenii PYR-1 | Mvan_1855 | - | 1e-154 | 72.33% (365) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6689|M.smegmatis_MC2_155 MSAA-----------ALEGVVVADFSRVLAGPYATMMLADFGAEVIKIER
Mvan_1855|M.vanbaalenii_PYR-1 -MTG-----------ALDGVVVVDFSRVLAGPYATMMLGDFGAEVIKVER
MAB_0824|M.abscessus_ATCC_1997 MTAA-----------ALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIER
MMAR_1494|M.marinum_M MTEP----------GALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEA
MUL_2446|M.ulcerans_Agy99 MTEP----------GALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEA
MAV_4024|M.avium_104 MSAAGAA-------GPLDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEL
Mflv_4465|M.gilvum_PYR-GCK MTTG-----------PLDGIRVIEVGTLISGPFAGRLLGDMGAEVIKVEP
TH_3339|M.thermoresistible__bu MTTEVETTATQPTTGPLHGIRVVEMGSLLAGPIVGQMMGDLGADVVKIED
Mb3300|M.bovis_AF2122/97 MPTSN-------PAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
Rv3272|M.tuberculosis_H37Rv MPTSN-------PAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
.*.*. * :. ::** . :: *:**:*:*:*
MSMEG_6689|M.smegmatis_MC2_155 PGTGDDTRQWGPPYDSTGVATYFNSVNRNKRSVALDLGSTEGREQARELI
Mvan_1855|M.vanbaalenii_PYR-1 PGVGDDTRQWGPPYDSSGVATYFNAVNRNKRSVVLDLSTPDGRQQARDLV
MAB_0824|M.abscessus_ATCC_1997 PVLGDDTRQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELA
MMAR_1494|M.marinum_M PGAPDPLRTWGQ-AEVDGHHVFWTVHARNKRAITLDLRRPQGRELFLELV
MUL_2446|M.ulcerans_Agy99 PGAPDPLRTWGQ-AEVDGHHVFWTVHARNKRAITLDLRRPQGRELFLELV
MAV_4024|M.avium_104 PRAPDPLRTWGQ-AEVDGHHVFWTVHARNKRAITLDLRHPRGRELFCELV
Mflv_4465|M.gilvum_PYR-GCK PGAPDPLRTWGQ-AELDGHHFFWTVHARNKKAVTLNLRVPEGRDLFLDLV
TH_3339|M.thermoresistible__bu PGKGDPLRQWGQ-NRPKGQSLWFSIVGRNKRSVTINLREPRGQELVRQLV
Mb3300|M.bovis_AF2122/97 PGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLA
Rv3272|M.tuberculosis_H37Rv PGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLA
* : . :: *.*:::.::* .:. *
MSMEG_6689|M.smegmatis_MC2_155 RRADIVVENFRPGTMEKLGLGYDDVRAIRPDVIYCSITGFGH-GGGAALP
Mvan_1855|M.vanbaalenii_PYR-1 AGADIVVENFRPGTMERLGLGYEDLRAVRPDVIYCSITGFGR-GGGAALP
MAB_0824|M.abscessus_ATCC_1997 GRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLP
MMAR_1494|M.marinum_M DKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKA
MUL_2446|M.ulcerans_Agy99 DKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKA
MAV_4024|M.avium_104 EKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQTGPDAAKA
Mflv_4465|M.gilvum_PYR-GCK ERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQTGPDAHKA
TH_3339|M.thermoresistible__bu AEADVLVENFRPGTMERWGLGYSDLAEINPRLVIVRVSGFGQDGPYASRP
Mb3300|M.bovis_AF2122/97 DTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRP
Rv3272|M.tuberculosis_H37Rv DTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRP
:*:::* **.**:*: .** . : . :: ::.:* * . .
MSMEG_6689|M.smegmatis_MC2_155 GYDLLVQAVGGLMSVTGTEPGDPTKAGVALVDVLAGMHALSGILVALAHR
Mvan_1855|M.vanbaalenii_PYR-1 GYDLLVQAVGGLMSVTGTEPGDPTKAGVALVDVLAGLHALSGILAALHHR
MAB_0824|M.abscessus_ATCC_1997 GYDLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYR
MMAR_1494|M.marinum_M GYASVAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRR
MUL_2446|M.ulcerans_Agy99 GYASVAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGPQGALAALYRR
MAV_4024|M.avium_104 GYASVAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRR
Mflv_4465|M.gilvum_PYR-GCK GYASVAEAASGLRHMNGFPGGPPPRLALSLGDSLAGMFAAQGALAALYRR
TH_3339|M.thermoresistible__bu GYGAIGEAMGGLRYVVGDPSTPPSRVGISIGDTLAALFATIGALAALRER
Mb3300|M.bovis_AF2122/97 GIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHR
Rv3272|M.tuberculosis_H37Rv GIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHR
* : * .*: * . : * :. . *.** *
MSMEG_6689|M.smegmatis_MC2_155 DRTGEGQRVDTNLFSVLLSSMVNQASGYLGAGVVPGIMGNRHPS------
Mvan_1855|M.vanbaalenii_PYR-1 GRTGEGQRVDTDLLSVLLSSMVNQASGFLGAGVVPAMMGNRHPS------
MAB_0824|M.abscessus_ATCC_1997 DRTGQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEALGNRHPS------
MMAR_1494|M.marinum_M SVTGTGQVVDVALTESCLALQESTISDYDVGGVVRGPSGTRLEG------
MUL_2446|M.ulcerans_Agy99 SVTGTGQVVDVALTESCLALQESTISDYDVGGVVRGPSGTRLKG------
MAV_4024|M.avium_104 SVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRGPSGTRLEG------
Mflv_4465|M.gilvum_PYR-GCK SVTGEGQIVDAALTESCLAVQESTIPDYDVGGVVRGPSGTRLEG------
TH_3339|M.thermoresistible__bu EISGRGQMVDSAIYEAVLGVMESLVPEWTVSGYQRERTGAILPK------
Mb3300|M.bovis_AF2122/97 ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
Rv3272|M.tuberculosis_H37Rv ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
.* .: *: : . :. . .
MSMEG_6689|M.smegmatis_MC2_155 ----ITPYQTFDTADR-PIAIAVGNDKQFRAFAAVIGSPELADDPRFSTN
Mvan_1855|M.vanbaalenii_PYR-1 ----IAPYQTFDTADR-PIAVAVGNDKQFRAFSTAIGQPELADDPRFVTN
MAB_0824|M.abscessus_ATCC_1997 ----IAPYQTFETADR-PIAIAVGNDKQFRLLVQALEMPRLARDDRFATN
MMAR_1494|M.marinum_M ----IAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDRFATH
MUL_2446|M.ulcerans_Agy99 ----IAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDRFATH
MAV_4024|M.avium_104 ----IAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRAELATDERFATH
Mflv_4465|M.gilvum_PYR-GCK ----IAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDERFADH
TH_3339|M.thermoresistible__bu ----IAPSNVYPTSDDTWILIAANQDTVFRRLAEAMGRPELAEDERYATH
Mb3300|M.bovis_AF2122/97 VGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQ
Rv3272|M.tuberculosis_H37Rv VGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQ
* : : ::* : ::. . : : : . *. * *: :
MSMEG_6689|M.smegmatis_MC2_155 PQRVAHRDVLCPLIEAALKAKGADHWYHELTAVGVPAGPINDLSEAFAFA
Mvan_1855|M.vanbaalenii_PYR-1 PARVANRDALCALIVPALKAHGADHWYAKLTTVGVPAGPINDLSEAFAFA
MAB_0824|M.abscessus_ATCC_1997 PLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFRFA
MMAR_1494|M.marinum_M RARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVKDR
MUL_2446|M.ulcerans_Agy99 RARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVKDR
MAV_4024|M.avium_104 VARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGPINTVAEVVNDP
Mflv_4465|M.gilvum_PYR-GCK VARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEVVEDP
TH_3339|M.thermoresistible__bu VARGEHQAELDEIVAEFTRRHTAAEVEALMHKHNVPVGKIYRPKEMLADP
Mb3300|M.bovis_AF2122/97 RSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTP
Rv3272|M.tuberculosis_H37Rv RSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTP
* : : : . . : .: : .
MSMEG_6689|M.smegmatis_MC2_155 EELGIEAVVQMPDGPTPQVANP----ITLSATPVTYRNSPPPLS------
Mvan_1855|M.vanbaalenii_PYR-1 RGLGIDAAVQVPGSPAPQVANP----VTMSATPVSYRSGPPALGDSPIAE
MAB_0824|M.abscessus_ATCC_1997 ERLGLDVAVTVPGSPEPQVANP----ISMSKTPVVYRNGPPRLGQSRA--
MMAR_1494|M.marinum_M QLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHNDD
MUL_2446|M.ulcerans_Agy99 QLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHNDD
MAV_4024|M.avium_104 QLRARDMLVEHYDERLRRNVLGPGIVPVLSESPGRVRNAGPARPGQHNDE
Mflv_4465|M.gilvum_PYR-GCK QLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSARPGQHNDE
TH_3339|M.thermoresistible__bu QFRARESITSVDHPVLG-EIQMQNVFPRLSRTRGSIRWPGPG-LGEHTDE
Mb3300|M.bovis_AF2122/97 LFAESDLTLEVGRGADTITVIR---TPARYASFRAVVTDPPPTAGEHNAV
Rv3272|M.tuberculosis_H37Rv LFAENDLTLEVGRGADTITVIR---TPARYASFRAVVTDPPPTAGEHNAV
: .
MSMEG_6689|M.smegmatis_MC2_155 ----------------------
Mvan_1855|M.vanbaalenii_PYR-1 KP--------------------
MAB_0824|M.abscessus_ATCC_1997 ----------------------
MMAR_1494|M.marinum_M VYIGLLGKSIEELEQLRAEEVL
MUL_2446|M.ulcerans_Agy99 VYIGLLGKSIEELEQLRAVEVL
MAV_4024|M.avium_104 VYRGLLGKTAEELEELRAQEVL
Mflv_4465|M.gilvum_PYR-GCK IYRDLLGRSAAELDKLQEEGVL
TH_3339|M.thermoresistible__bu VLR-QLGLSDEELQKLHDAGVV
Mb3300|M.bovis_AF2122/97 FLARP-----------------
Rv3272|M.tuberculosis_H37Rv FLARP-----------------