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GAGAGNRTGPLSGVRVVDLTAMVMGPYCTQIMADMGADVIKIEPPQGDDTRYVSVGPAAGMSGVFVNVNR GKRSAVIDLKSDSGQAAVRALIEGADVFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRRGPNRD LPAYDDTIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYATMMALFHRERTGQGQEVEIGMFEAVA SFMLVEHANGAMFDPPLGPAVYPRTVAPNRRPYRTSDGYLAALIYNDKHWAAFVDAVRPPWASEQYATLE GRARQIDTVYALLAETFAARTTQEWLDLLEELEIPASALSSPAELFDNQHLNAVGFFETIDTAHGPVRFP GVPTWFSRTPGRVLGPAPQLGADTSAVLEELGINAADAQPAGPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4811 | - | - | 100% (395) | hypothetical protein MUL_4811 |
| M. ulcerans Agy99 | MUL_0328 | - | 2e-43 | 32.35% (405) | acyl-CoA transferase |
| M. ulcerans Agy99 | MUL_1046 | - | 2e-43 | 32.81% (381) | acyl-CoA transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 6e-38 | 30.43% (322) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_1791 | - | 0.0 | 79.58% (382) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 6e-38 | 30.43% (322) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 3e-46 | 33.96% (374) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_0311 | - | 0.0 | 99.49% (395) | hypothetical protein MMAR_0311 |
| M. avium 104 | MAV_5204 | - | 0.0 | 80.38% (372) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_5623 | - | 1e-177 | 79.09% (373) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_3725 | - | 1e-178 | 78.80% (382) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. vanbaalenii PYR-1 | Mvan_4959 | - | 0.0 | 79.47% (375) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4811|M.ulcerans_Agy99 -----------MGAGAGNRTGPLSGVRVVDLTAMVMGPYCTQIMADMGAD
MMAR_0311|M.marinum_M MSNCGSDCDSSLGAGAGKRTGPLSGVRVVDLTAMVMGPYCTQIMADMGAD
MSMEG_5623|M.smegmatis_MC2_155 -----------------MTGGPLQGVRVIDLTAMVMGPYCTQIMADMGAD
TH_3725|M.thermoresistible__bu -------------------------VRVVDLTAMVMGPYCTQIMADMGAE
Mflv_1791|M.gilvum_PYR-GCK ----------------MADSGPLAGIRVVDLTAMVMGPYCTQIMADMGAD
Mvan_4959|M.vanbaalenii_PYR-1 ----------------MAENGPLAGIRVVDLTAMVMGPYCTQIMADMGAE
MAV_5204|M.avium_104 ----------------------MAGVRVIDLTAMVMGPYCTQIMADMGAD
Mb3300|M.bovis_AF2122/97 -------------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAE
Rv3272|M.tuberculosis_H37Rv -------------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAE
MAB_0824|M.abscessus_ATCC_1997 -----------------MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAE
. *:*:: : ** . :: *:**:
MUL_4811|M.ulcerans_Agy99 VIKIEPPQGDDTRYVSVGP--AAGMSGVFVNVNRGKRSAVIDLKSDSGQA
MMAR_0311|M.marinum_M VIKIEPPQGDDTRYVSVGP--AAGMSGVFVNVNRGKRSAVIDLKSDSGQA
MSMEG_5623|M.smegmatis_MC2_155 VIKVEPPQGDDTRYVSVGP--APGLSGVFVNVNRGKRSIVLDLRTASGKA
TH_3725|M.thermoresistible__bu VIKVEPPAGDNTRFISVGP--RSGMSGVFVNVNRGKRSVVLDLRSEDGAG
Mflv_1791|M.gilvum_PYR-GCK VIKVEPPQGDNTRYISVGP--VSGMSGVFVNVNRGKRSIVLDLRSVEGKA
Mvan_4959|M.vanbaalenii_PYR-1 VIKVEPPEGDNTRFISVGP--VPGMSGVFVNVNRGKRSVVLDLRSDEGRA
MAV_5204|M.avium_104 VIKVEPPQGDNTRYISVGP--APGMSGVFVNVNRGKRSVVLDLQTDAGAR
Mb3300|M.bovis_AF2122/97 VIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQ
Rv3272|M.tuberculosis_H37Rv VIKVEAPGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQ
MAB_0824|M.abscessus_ATCC_1997 VIKIERPVLGDDTRQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQH
***:* * : * **.*:* .:** : .
MUL_4811|M.ulcerans_Agy99 AVRALIEGADVFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRRG
MMAR_0311|M.marinum_M AVRALIEGADVFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRRG
MSMEG_5623|M.smegmatis_MC2_155 DLRDLIADADVFIHSMRAKAIAKLGFGYDDVAAINPRIVYTNCYGYGRRG
TH_3725|M.thermoresistible__bu ALRALIARADVFIHSMRAKAIAKLGFGYPDVAAINPAIVYTNCYGYGRRG
Mflv_1791|M.gilvum_PYR-GCK ALRALIERADVFIHSMRSKAIAKLGFGYDDVAAVNPTIIYTNCYGYGRRG
Mvan_4959|M.vanbaalenii_PYR-1 AVRALVGRADVFIHSMRAKAITKLGLGYDDVAAVNPSIVYTNCYGYGRRG
MAV_5204|M.avium_104 ALRGLVETADVFIHSMRAKAIARLGFGYDDVAAINPAVVYTNCYGYGRRG
Mb3300|M.bovis_AF2122/97 QMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNG
Rv3272|M.tuberculosis_H37Rv QMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNG
MAB_0824|M.abscessus_ATCC_1997 RARELAGRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFG-RG
* ***.:. :*. :: ::*:. .: ** ::* .:* .*
MUL_4811|M.ulcerans_Agy99 PNRDLPAYDDTIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYATM
MMAR_0311|M.marinum_M PNRDLPAYDDTIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYATM
MSMEG_5623|M.smegmatis_MC2_155 PDADRPAYDDTIQAECGLPAVQKQLTGEAAYVGTIMADKVAGLTALYSTM
TH_3725|M.thermoresistible__bu PDADRPAYDDTIQAECGLPAVQEQLTGEANYVGTIMADKVAGLTALYATM
Mflv_1791|M.gilvum_PYR-GCK PERDRPAYDDTIQAECGLPAVQKQLTGEADYVGTIMADKVAGLTALYATM
Mvan_4959|M.vanbaalenii_PYR-1 PERDRPAYDDTIQAECGIPAVQQQLTGEPDYVGTIMADKVAGLTALYATT
MAV_5204|M.avium_104 PDRDRPAYDDTIQAECGLPAVQQQLTGQADYVGTIMADKIAGLTALYATT
Mb3300|M.bovis_AF2122/97 PHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVL
Rv3272|M.tuberculosis_H37Rv PHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVL
MAB_0824|M.abscessus_ATCC_1997 AGADLPGYDLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGIL
. . *. * : * *: : ... : :.* :. .
MUL_4811|M.ulcerans_Agy99 MALFHRERTGQGQEVEIGMFEAVASFMLVEHANGAMFDPPLGPAVYPRT-
MMAR_0311|M.marinum_M MALFHRERTGQGQEVEIGMFEAVASFMLVEHANGAMFDPPLGPAVYPRT-
MSMEG_5623|M.smegmatis_MC2_155 MALFHRERTGEGQEVEVSMFETMAAFMLVEHANGAMFDPPLGPAVYPRT-
TH_3725|M.thermoresistible__bu MALFHRERTGEGQEVEVAMFETMASFMLVEHANGAMFDPPLGPAVYPRT-
Mflv_1791|M.gilvum_PYR-GCK MALFHRERTGEGQEVEVAMFETMASFMLVEHANGAMFDPPLGPAVYPRT-
Mvan_4959|M.vanbaalenii_PYR-1 MALFHRQRTGEGQEVEVAMFETMASFMLVEHANGAMFDPPLGPAVYPRT-
MAV_5204|M.avium_104 MALFHRERTGQGQEVEVAMFETMASFMLVEHANGALFDPPLGPAVYPRT-
Mb3300|M.bovis_AF2122/97 AALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPK
Rv3272|M.tuberculosis_H37Rv AALLHRERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPK
MAB_0824|M.abscessus_ATCC_1997 AALSYRDRTGQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEALGNRHP-
** :*:*.* .: *: : .. . : . .
MUL_4811|M.ulcerans_Agy99 ---------VAPNRRPYRTSDGYLAALIYNDKHWAAFVDAVRPPWA---S
MMAR_0311|M.marinum_M ---------VAPNRRPYRTSDGYLAALIYNDKHWAAFVDAVRPPWA---S
MSMEG_5623|M.smegmatis_MC2_155 ---------VAPNRRPYETKDGHIAALIYNDKHWNAFIDAVQPPWN---R
TH_3725|M.thermoresistible__bu ---------VAPNRRPYETKDGHIAALIYNDKHWQAFVDAVAPAWYEENR
Mflv_1791|M.gilvum_PYR-GCK ---------VAPNRRPYRTKDGHIAALIYNDKHWNAFIAAVRPPWA---S
Mvan_4959|M.vanbaalenii_PYR-1 ---------VAPNRRPYRTKDGYIAVLIYNDKHWNAFIDAVQPPWS---S
MAV_5204|M.avium_104 ---------VAPNRRPYRTSDGYIAALIYNDKHWNAFMNAVRPPWA---S
Mb3300|M.bovis_AF2122/97 AKRRKGVGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVE-D
Rv3272|M.tuberculosis_H37Rv AKRRKGVGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVE-D
MAB_0824|M.abscessus_ATCC_1997 ---------SIAPYQTFETADRPIAIAVGNDKQFRLLVQALEMPRLAR-D
.:.* * :. *:: : : .
MUL_4811|M.ulcerans_Agy99 EQYATLEGRARQIDTVYALLAETFAARTTQEWLDLLEELEIPASALSSPA
MMAR_0311|M.marinum_M EQYATLEGRARQIDTVYALLAETFAARTTQEWLDLLEELEIPASALSSPA
MSMEG_5623|M.smegmatis_MC2_155 PEYATLEARARQIDTVYGLLAQTLKERTTAEWLDLFDDLEIPAAPIHTPD
TH_3725|M.thermoresistible__bu TRYATLENRARHIDTVYSLIAETLKERTTDEWLTLFRELEIPAAPINTPD
Mflv_1791|M.gilvum_PYR-GCK ELYSTLESRAHQIDTVYGLVAETLAERTTEEWLNLFRELEIPAAPLNTPD
Mvan_4959|M.vanbaalenii_PYR-1 DLYSTLEARAHRIDTVYGLVAETLAERTTADWLDLFRELEIPAAPLNTPD
MAV_5204|M.avium_104 ELYATLEQRAAQIDTVYGLVAETMKERSTAEWLELLGELEIPAAPLNSPG
Mb3300|M.bovis_AF2122/97 QRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWK
Rv3272|M.tuberculosis_H37Rv QRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWK
MAB_0824|M.abscessus_ATCC_1997 DRFATNPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIA
:: * . : : : :.: :* : : *
MUL_4811|M.ulcerans_Agy99 ELFDNQHLNAVGFFETIDTAHGPVRFPGVPTWFSRTPGRVLGPAPQLGAD
MMAR_0311|M.marinum_M ELFDNQHLNAVGFFETIDTAHGPVRFPGVPTWFSRTPGRVSGPAPQLGAD
MSMEG_5623|M.smegmatis_MC2_155 ALFDNPHLNAVGLFETVDTQYGPVRFPGVPTWFSKTPGRVRGFAPELGAD
TH_3725|M.thermoresistible__bu ALFDNEHLNAVGLFETVDTPHGPVRFPGVPTWFSRTPGRVGGTAPELGAD
Mflv_1791|M.gilvum_PYR-GCK ALFDDPHLNAVGLFETVDTPHGPVKFPGVPTWFSRTPGKVRGPAPELGAD
Mvan_4959|M.vanbaalenii_PYR-1 ALFDDPHLNAVGLFETVDTPHGPVRFPGVPTWFSRTPGKVRGPAPELGAD
MAV_5204|M.avium_104 ALFDDPHLNAVGMFQTVDTPHGPVRFPGVPTWFSQTPGRVAGPAPELGAH
Mb3300|M.bovis_AF2122/97 QVVDTPLFAESDLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEH
Rv3272|M.tuberculosis_H37Rv QVVDTPLFAENDLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEH
MAB_0824|M.abscessus_ATCC_1997 EAFRFAERLGLDVAVTVPGSPE--PQVANPISMSKTPVVYRNGPPRLGQS
. .. : * : . .* *
MUL_4811|M.ulcerans_Agy99 TSAVLEELGINAADAQPAGPA--
MMAR_0311|M.marinum_M TSAVLEELGINAADAQPAGPA--
MSMEG_5623|M.smegmatis_MC2_155 TDDVLAEVRPQNKAG--------
TH_3725|M.thermoresistible__bu TEAVLAELGLTPQAGREPAQGMS
Mflv_1791|M.gilvum_PYR-GCK TAAVLAELGLDTVAAEQVS----
Mvan_4959|M.vanbaalenii_PYR-1 TAAVLDELGLGG-----------
MAV_5204|M.avium_104 TDEVLAEIGAREGKEL-------
Mb3300|M.bovis_AF2122/97 NAVFLARP---------------
Rv3272|M.tuberculosis_H37Rv NAVFLARP---------------
MAB_0824|M.abscessus_ATCC_1997 RA---------------------