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PKDTPEKSGPLAGFTVVALEQAVSAPMCTRVLADFGARVIKVENPKGGDFARDYDDVVLGPGGLAAHFVW ANRGKESITLDLKTPGGMDVLHKLLDTADALVSNLAPGAMARMGLAPADLAERHPQVIPVEIDGYGSGGP LSHKRAYDLLVQAESGACAVTGHPDMPAKPGPPVADISTGLYAALSIMALLIGRLRRPENGAAPAVAVSL FDTMTDIMGYPLTYTQHSGVDQQPLGMSSPAVAPYGAFSTRDGQTVVLGTTNDREWQRLAREIIDRPDLA DDPRFATNSDRCAHRDVLNEAIGTWCAQHDLAEIQQIADEAGIGNSRFNRPSEVIAHQHLKDRDRWRQVA TPKGEIAALLPPPVIAGYEMPMGAVPGLGEHTDHILADIGLSAEEIASLREQGAVGPAMQTRSEQSHA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4834 | - | - | 100% (419) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_1992 | - | 3e-89 | 45.83% (384) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_4046 | - | 2e-75 | 40.05% (387) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 4e-42 | 31.59% (402) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2443 | - | 0.0 | 78.41% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 4e-42 | 31.59% (402) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 4e-40 | 29.48% (407) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1267 | - | 3e-42 | 31.44% (404) | acyl-CoA transferase |
| M. avium 104 | MAV_2651 | - | 2e-93 | 47.03% (387) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_2496 | - | 0.0 | 78.86% (402) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_2621 | - | 1e-41 | 31.19% (404) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_4208 | - | 0.0 | 78.30% (401) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4834|M.smegmatis_MC2_155 MPKDTPEKSGPLAGFTVVALEQAVSAPMCTRVLADFGARVIKVENPKGGD
TH_2496|M.thermoresistible__bu MAESEHADPAPLAGITVVALEQAVSAPMCTRVLADFGARVIKVENPDGGD
Mflv_2443|M.gilvum_PYR-GCK MTASQ--SAGPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
Mvan_4208|M.vanbaalenii_PYR-1 MSSSQP-SAAPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
MAV_2651|M.avium_104 -----------------MSLEQAVAAPYATRQLADLGARVIKVERPQGGD
Mb3300|M.bovis_AF2122/97 --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAP-GGE
Rv3272|M.tuberculosis_H37Rv --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAP-GGE
MMAR_1267|M.marinum_M --MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEAP-GGE
MUL_2621|M.ulcerans_Agy99 --MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEAP-GGE
MAB_4651c|M.abscessus_ATCC_199 -------MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPD
: : ::.* . : * *:**.::*:* * . :
MSMEG_4834|M.smegmatis_MC2_155 FARDYDDVVLGPGGLAAHFVWANRGKESITLDLKTPGGMDVLHKLLDTAD
TH_2496|M.thermoresistible__bu FARHYDDVVKG---QAAHFVWANRGKESVTLNLKSEAGMAVLHRLLDEAD
Mflv_2443|M.gilvum_PYR-GCK FARAYDDVVNGPGGLAAHFVWSNRGKESVTLNTKSPAGLEVLHRLLDRAD
Mvan_4208|M.vanbaalenii_PYR-1 FARDYDDVVNGPGGLAAHFVWSNRGKESVTLNTKTAGGLDLLHRLLDRAD
MAV_2651|M.avium_104 FARGYDRTVHG---ESSYFVWLNRGKESLTVDLKQPEGRRIVERLLEGAD
Mb3300|M.bovis_AF2122/97 AARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
Rv3272|M.tuberculosis_H37Rv AARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
MMAR_1267|M.marinum_M AARHITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILRLADTAD
MUL_2621|M.ulcerans_Agy99 AARHITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILRLADTAD
MAB_4651c|M.abscessus_ATCC_199 PLRTWGQAEVDG--HHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKSD
* . .: *.*:::::: . . * : :*
MSMEG_4834|M.smegmatis_MC2_155 ALVSNLAPGAMARMGLAPADLAERHPQVIPVEIDGYGSGGPLSHKRAYDL
TH_2496|M.thermoresistible__bu VLVSNLAPGALARMGLAADDLKTSHPRVLPVQIDGYGAGGPISHKRAYDL
Mflv_2443|M.gilvum_PYR-GCK AFVSNLAPGATARLGLSPADLAERHPQVIPVEIDGYGPGGPISHKRAYDL
Mvan_4208|M.vanbaalenii_PYR-1 AFVSNLAPGATARLGVAPADLAARHPRVIPVEIDGYGPGGPLSHKRAYDL
MAV_2651|M.avium_104 VLVQNLAPGAAARMGLDTESVARAHPRTITATISGYGQDGPWRDRKAYDL
Mb3300|M.bovis_AF2122/97 VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
Rv3272|M.tuberculosis_H37Rv VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
MMAR_1267|M.marinum_M VVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGTRPGVDL
MUL_2621|M.ulcerans_Agy99 VVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGTRPGVDL
MAB_4651c|M.abscessus_ATCC_199 VIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYAS
..:. : **. : *: : : : . : .:* ** : .
MSMEG_4834|M.smegmatis_MC2_155 LVQAESGACAVTGHP-DMPAKPGPPVADISTGLYAALSIMALLIGRLRR-
TH_2496|M.thermoresistible__bu LIQAESGACAVTGYP-GMPAKPGPPVADISTGLYAALSVMALLYGRDRRD
Mflv_2443|M.gilvum_PYR-GCK LVQAESGSCAVTGYP-GMPAKPGPAVADFTSGLYAAMSIVSLLYGRATR-
Mvan_4208|M.vanbaalenii_PYR-1 LVQAESGSCAVTGYP-GMPAKPGPAVADFSTGLYAAISILALLYGRARH-
MAV_2651|M.avium_104 LVQAEAGLLSVTGSP-AEVARTGVSIADIAAGMFAFSGILTALYTRATT-
Mb3300|M.bovis_AF2122/97 VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
Rv3272|M.tuberculosis_H37Rv VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
MMAR_1267|M.marinum_M MVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHVLAQAVLAALLNRERH-
MUL_2621|M.ulcerans_Agy99 MVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHVLAQAVLAALLNRERH-
MAB_4651c|M.abscessus_ATCC_199 VAEAASGLRHLNGFPGGPPPRMALSIGDTLAGMFAAQGALAALYRRTVT-
: * :* * : * :* . :: * *
MSMEG_4834|M.smegmatis_MC2_155 -PENGAAPAVAVSLFDTMTDIMGYPLTYTQHSGVDQQPLGMSSP------
TH_2496|M.thermoresistible__bu RATPGPVPAVAVSLFDTMTDIMGYQLTYTQHSGVDQQPLGMSSP------
Mflv_2443|M.gilvum_PYR-GCK -PEPGPAPHVELSLFDVMTDVMGYALTYTQHSGIDQEPLGVGSP------
Mvan_4208|M.vanbaalenii_PYR-1 -PGSAPAPSVELSLFDVMTDVMGYALTYTQHSGIDQEPLGVGSP------
MAV_2651|M.avium_104 ----GAVRPVSVSLFDALVEWMSQPLYYGRYGGKAPPRTGARHP------
Mb3300|M.bovis_AF2122/97 ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK-PEPAPKAKRR
Rv3272|M.tuberculosis_H37Rv ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK-PEPAPKAKRR
MMAR_1267|M.marinum_M ----GVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAGARR
MUL_2621|M.ulcerans_Agy99 ----GVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAGARR
MAB_4651c|M.abscessus_ATCC_199 ----GRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEG-----
. * :: : :
MSMEG_4834|M.smegmatis_MC2_155 -----AVAPYGAFSTRDGQTVVLGTTNDREWQRLAREIIDRPDLADDPRF
TH_2496|M.thermoresistible__bu -----AVAPYGAFRTRDGQTVVLGTTNDREWQRLARDIIERPDLADDPAY
Mflv_2443|M.gilvum_PYR-GCK -----AVAPYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRF
Mvan_4208|M.vanbaalenii_PYR-1 -----AVAPYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRF
MAV_2651|M.avium_104 -----TIAPYGPVTAGDGGTVLLGVQNSAEWLRFCEIVLERRDLVDEPRF
Mb3300|M.bovis_AF2122/97 KGVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRF
Rv3272|M.tuberculosis_H37Rv KGVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRF
MMAR_1267|M.marinum_M KRVAFATQPSDAFRAADG-YLLISAYVPKHWQRLCEIIG-RPDLLDDERF
MUL_2621|M.ulcerans_Agy99 KRVAFATQPSDAFRAADG-YLLISAYVPKHWQRLCEIIG-QPDLLDDERF
MAB_4651c|M.abscessus_ATCC_199 ------IAPSNIYQSADGSWVVIAANQDTVFRRLCEAMG-RPELSSDARF
* . : ** :::.. : :.. : : :* .: :
MSMEG_4834|M.smegmatis_MC2_155 ATNSDRCAHRDVLNEAIGTWCAQHDLAEIQQIADEAGIGNSRFNRPSEVI
TH_2496|M.thermoresistible__bu ATNSDRVRHRDVLNEAIAAWCARHDLAHIQKTADDAGIGNSRYNLPSEVV
Mflv_2443|M.gilvum_PYR-GCK ATNPGRCANRDVLEEAIGAWCARHDLAEIQDKADRAGIGNSRYNLPSEVI
Mvan_4208|M.vanbaalenii_PYR-1 ATNSDRCAHRQILEEAIGSWCAQHDLAEIQKTADAAGIGNSRYNLPSEVV
MAV_2651|M.avium_104 ATNPDRVAHRDELESIITTVAARLSAEELEARLQSAGVAHARMNGVDHLW
Mb3300|M.bovis_AF2122/97 AEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVV
Rv3272|M.tuberculosis_H37Rv AEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVV
MMAR_1267|M.marinum_M IDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYTWKQVV
MUL_2621|M.ulcerans_Agy99 IDQRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYTWKQVV
MAB_4651c|M.abscessus_ATCC_199 ANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADVV
: * : * : * . *: .:
MSMEG_4834|M.smegmatis_MC2_155 AHQHLKDRDRWRQVATPKGEIAALLP---PPVIAGYEMPMGAVP-GLGEH
TH_2496|M.thermoresistible__bu AHPHLSARDRWRPVDTPNGQITALRP---PPVIEGFEQPMGPVP-GLGQH
Mflv_2443|M.gilvum_PYR-GCK AHPHLVARDRWRTVATPKGDIQALRP---PPVISDFEQPMGAIP-GLGEH
Mvan_4208|M.vanbaalenii_PYR-1 VHPHLAARDRWRTVATPKGDIQALRP---PPVISDFEQPMGAIP-GLGEH
MAV_2651|M.avium_104 LHPVLVGRDRWHEIQTPGGPAAALPP---PAGLAGVDPVIGDVP-ALGEH
Mb3300|M.bovis_AF2122/97 DTPLFAESDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEH
Rv3272|M.tuberculosis_H37Rv DTPLFAENDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEH
MMAR_1267|M.marinum_M TTPLFAENELALQVGSGDDAVTVIRT---PARYSSFSAVLAEPPAATGEH
MUL_2621|M.ulcerans_Agy99 TTPLFAENELALQVDSGDDAVTVIRT---PARYSSFSAVLADPPPATGEH
MAB_4651c|M.abscessus_ATCC_199 QDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQD
: : .: . * . * *:.
MSMEG_4834|M.smegmatis_MC2_155 TDHILAD-IGLSAEEIASLREQGAVGPAMQTRSEQSHA
TH_2496|M.thermoresistible__bu TDAVLSGLLGMTDDEIAALREQGAIGPAYN--------
Mflv_2443|M.gilvum_PYR-GCK TDAVLTE-FGVSAEELAQLRAEGAIGPAYRG-------
Mvan_4208|M.vanbaalenii_PYR-1 TDAVLTE-IGVTPDELRQLRADGAIGPAYRG-------
MAV_2651|M.avium_104 SRKILHE-LGYSAQATDELIAAGVTTA-----------
Mb3300|M.bovis_AF2122/97 NAVFLARP------------------------------
Rv3272|M.tuberculosis_H37Rv NAVFLARP------------------------------
MMAR_1267|M.marinum_M NETLLGES------------------------------
MUL_2621|M.ulcerans_Agy99 NETLLGES------------------------------
MAB_4651c|M.abscessus_ATCC_199 NDDVYVGLLGKSAQDIERLRAEGVL-------------
. .