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M. thermoresistible (build 8) TH_2496 (-)

annotation: L-carnitine dehydratase/bile acid-inducible protein F
coordinates: 558302 - 559537
length: 412

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2496--100% (412)L-carnitine dehydratase/bile acid-inducible protein F
M. thermoresistible (build 8)TH_3339-7e-5131.25% (400) PUTATIVE putative L-carnitine dehydratase/bile acid-inducible
M. thermoresistible (build 8)TH_3905-5e-4933.74% (412) PUTATIVE Formyl-CoA transferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3300-5e-3830.02% (403) hypothetical protein Mb3300
M. gilvum PYR-GCKMflv_2443-1e-17975.43% (403) L-carnitine dehydratase/bile acid-inducible protein F
M. tuberculosis H37RvRv3272-4e-3830.02% (403) hypothetical protein Rv3272
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4651c-1e-4230.79% (406) putative L-carnitine dehydratase
M. marinum MMMAR_1494-1e-4231.20% (407) hypothetical protein MMAR_1494
M. avium 104MAV_2651-1e-9245.97% (385) L-carnitine dehydratase/bile acid-inducible protein F
M. smegmatis MC2 155MSMEG_4834-0.078.86% (402) L-carnitine dehydratase/bile acid-inducible protein F
M. ulcerans Agy99MUL_2446-3e-4231.11% (405) hypothetical protein MUL_2446
M. vanbaalenii PYR-1Mvan_4208-0.074.63% (410) L-carnitine dehydratase/bile acid-inducible protein F

CLUSTAL 2.0.9 multiple sequence alignment


TH_2496|M.thermoresistible__bu      MAESEHADPAPLAGITVVALEQAVSAPMCTRVLADFGARVIKVENPDGGD
MSMEG_4834|M.smegmatis_MC2_155      MPKDTPEKSGPLAGFTVVALEQAVSAPMCTRVLADFGARVIKVENPKGGD
Mflv_2443|M.gilvum_PYR-GCK          MTASQ--SAGPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
Mvan_4208|M.vanbaalenii_PYR-1       MSSSQP-SAAPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
MAV_2651|M.avium_104                -----------------MSLEQAVAAPYATRQLADLGARVIKVERPQGGD
Mb3300|M.bovis_AF2122/97            --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAP-GGE
Rv3272|M.tuberculosis_H37Rv         --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAP-GGE
MMAR_1494|M.marinum_M               -----MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAP-GAP
MUL_2446|M.ulcerans_Agy99           -----MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAP-GAP
MAB_4651c|M.abscessus_ATCC_199      -------MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPP-GAP
                                                     : :   ::.* . : * *:** ::*:* * *. 

TH_2496|M.thermoresistible__bu      FARHYDDVVKG---QAAHFVWANRGKESVTLNLKSEAGMAVLHRLLDEAD
MSMEG_4834|M.smegmatis_MC2_155      FARDYDDVVLGPGGLAAHFVWANRGKESITLDLKTPGGMDVLHKLLDTAD
Mflv_2443|M.gilvum_PYR-GCK          FARAYDDVVNGPGGLAAHFVWSNRGKESVTLNTKSPAGLEVLHRLLDRAD
Mvan_4208|M.vanbaalenii_PYR-1       FARDYDDVVNGPGGLAAHFVWSNRGKESVTLNTKTAGGLDLLHRLLDRAD
MAV_2651|M.avium_104                FARGYDRTVHG---ESSYFVWLNRGKESLTVDLKQPEGRRIVERLLEGAD
Mb3300|M.bovis_AF2122/97            AARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
Rv3272|M.tuberculosis_H37Rv         AARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
MMAR_1494|M.marinum_M               DPLRTWGQAEVDG-HHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSD
MUL_2446|M.ulcerans_Agy99           DPLRTWGQAEVDG-HHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSD
MAB_4651c|M.abscessus_ATCC_199      DPLRTWGQAEVDG-HHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKSD
                                     .               .:    *.*.::*::     .   .  * : :*

TH_2496|M.thermoresistible__bu      VLVSNLAPGALARMGLAADDLKTSHPRVLPVQIDGYGAGGPISHKRAYDL
MSMEG_4834|M.smegmatis_MC2_155      ALVSNLAPGAMARMGLAPADLAERHPQVIPVEIDGYGSGGPLSHKRAYDL
Mflv_2443|M.gilvum_PYR-GCK          AFVSNLAPGATARLGLSPADLAERHPQVIPVEIDGYGPGGPISHKRAYDL
Mvan_4208|M.vanbaalenii_PYR-1       AFVSNLAPGATARLGVAPADLAARHPRVIPVEIDGYGPGGPLSHKRAYDL
MAV_2651|M.avium_104                VLVQNLAPGAAARMGLDTESVARAHPRTITATISGYGQDGPWRDRKAYDL
Mb3300|M.bovis_AF2122/97            VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
Rv3272|M.tuberculosis_H37Rv         VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
MMAR_1494|M.marinum_M               IVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYAS
MUL_2446|M.ulcerans_Agy99           IVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYAS
MAB_4651c|M.abscessus_ATCC_199      VIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYAS
                                     .:. : **:  : .:    :   :   : . : .**  **   : .   

TH_2496|M.thermoresistible__bu      LIQAESGACAVTGYP-GMPAKPGPPVADISTGLYAALSVMALLYGRDRRD
MSMEG_4834|M.smegmatis_MC2_155      LVQAESGACAVTGHP-DMPAKPGPPVADISTGLYAALSIMALLIGRLRR-
Mflv_2443|M.gilvum_PYR-GCK          LVQAESGSCAVTGYP-GMPAKPGPAVADFTSGLYAAMSIVSLLYGRATR-
Mvan_4208|M.vanbaalenii_PYR-1       LVQAESGSCAVTGYP-GMPAKPGPAVADFSTGLYAAISILALLYGRARH-
MAV_2651|M.avium_104                LVQAEAGLLSVTGSP-AEVARTGVSIADIAAGMFAFSGILTALYTRATT-
Mb3300|M.bovis_AF2122/97            VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
Rv3272|M.tuberculosis_H37Rv         VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
MMAR_1494|M.marinum_M               VAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRRSVT-
MUL_2446|M.ulcerans_Agy99           VAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGPQGALAALYRRSVT-
MAB_4651c|M.abscessus_ATCC_199      VAEAASGLRHLNGFPGGPPPRMALSIGDTLAGMFAAQGALAALYRRTVT-
                                    :  * :*       *          : *  :*     . :: *  *    

TH_2496|M.thermoresistible__bu      RATPGPVPAVAVSLFDTMTDIMGYQLTYTQHSGVDQ------QPLGMSSP
MSMEG_4834|M.smegmatis_MC2_155      -PENGAAPAVAVSLFDTMTDIMGYPLTYTQHSGVDQ------QPLGMSSP
Mflv_2443|M.gilvum_PYR-GCK          -PEPGPAPHVELSLFDVMTDVMGYALTYTQHSGIDQ------EPLGVGSP
Mvan_4208|M.vanbaalenii_PYR-1       -PGSAPAPSVELSLFDVMTDVMGYALTYTQHSGIDQ------EPLGVGSP
MAV_2651|M.avium_104                ----GAVRPVSVSLFDALVEWMSQPLYYGRYGGKAP------PRTGARHP
Mb3300|M.bovis_AF2122/97            ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
Rv3272|M.tuberculosis_H37Rv         ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
MMAR_1494|M.marinum_M               ----GTGQVVDVALTESCLALQESTISDYDVGGVVR------GPSGTRLE
MUL_2446|M.ulcerans_Agy99           ----GTGQVVDVALTESCLALQESTISDYDVGGVVR------GPSGTRLK
MAB_4651c|M.abscessus_ATCC_199      ----GRGQVVDAALTESCLAVQESTIPDYDVGRVVR------GPSGTRLE
                                        .    *  :: :         :                   .    

TH_2496|M.thermoresistible__bu      AV----APYGAFRTRDGQTVVLGTTNDREWQRLARDIIERPDLADDPAYA
MSMEG_4834|M.smegmatis_MC2_155      AV----APYGAFSTRDGQTVVLGTTNDREWQRLAREIIDRPDLADDPRFA
Mflv_2443|M.gilvum_PYR-GCK          AV----APYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
Mvan_4208|M.vanbaalenii_PYR-1       AV----APYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
MAV_2651|M.avium_104                TI----APYGPVTAGDGGTVLLGVQNSAEWLRFCEIVLERRDLVDEPRFA
Mb3300|M.bovis_AF2122/97            GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
Rv3272|M.tuberculosis_H37Rv         GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
MMAR_1494|M.marinum_M               GI----APSNIYRSADESWVVIAANQDTVFTRLCQAMG-CPELATDDRFA
MUL_2446|M.ulcerans_Agy99           GI----APSNIYRSADESWVVIAANQDTVFTRLCQAMG-CPELATDDRFA
MAB_4651c|M.abscessus_ATCC_199      GI----APSNIYQSADGSWVVIAANQDTVFRRLCEAMG-RPELSSDARFA
                                     :     * .   : *   :::..     : :..  :    :*  :  :*

TH_2496|M.thermoresistible__bu      TNSDRVRHRDVLNEAIAAWCARHDLAHIQKTADDAGIGNSRYNLPSEVVA
MSMEG_4834|M.smegmatis_MC2_155      TNSDRCAHRDVLNEAIGTWCAQHDLAEIQQIADEAGIGNSRFNRPSEVIA
Mflv_2443|M.gilvum_PYR-GCK          TNPGRCANRDVLEEAIGAWCARHDLAEIQDKADRAGIGNSRYNLPSEVIA
Mvan_4208|M.vanbaalenii_PYR-1       TNSDRCAHRQILEEAIGSWCAQHDLAEIQKTADAAGIGNSRYNLPSEVVV
MAV_2651|M.avium_104                TNPDRVAHRDELESIITTVAARLSAEELEARLQSAGVAHARMNGVDHLWL
Mb3300|M.bovis_AF2122/97            EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
Rv3272|M.tuberculosis_H37Rv         EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
MMAR_1494|M.marinum_M               THRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVK
MUL_2446|M.ulcerans_Agy99           THRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVK
MAB_4651c|M.abscessus_ATCC_199      NHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADVVQ
                                     :  *  :   *   :    *     .     .  *:     :   .:  

TH_2496|M.thermoresistible__bu      HPHLSARDRWRPVDTPNGQITALRP---PPVIEGFEQPMGPVPG-LGQHT
MSMEG_4834|M.smegmatis_MC2_155      HQHLKDRDRWRQVATPKGEIAALLP---PPVIAGYEMPMGAVPG-LGEHT
Mflv_2443|M.gilvum_PYR-GCK          HPHLVARDRWRTVATPKGDIQALRP---PPVISDFEQPMGAIPG-LGEHT
Mvan_4208|M.vanbaalenii_PYR-1       HPHLAARDRWRTVATPKGDIQALRP---PPVISDFEQPMGAIPG-LGEHT
MAV_2651|M.avium_104                HPVLVGRDRWHEIQTPGGPAAALPP---PAGLAGVDPVIGDVPA-LGEHS
Mb3300|M.bovis_AF2122/97            TPLFAESDLTLEVGRGADTITVIR---TPARYASFRAVVTDPPPTAGEHN
Rv3272|M.tuberculosis_H37Rv         TPLFAENDLTLEVGRGADTITVIR---TPARYASFRAVVTDPPPTAGEHN
MMAR_1494|M.marinum_M               DRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHN
MUL_2446|M.ulcerans_Agy99           DRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHN
MAB_4651c|M.abscessus_ATCC_199      DPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQDN
                                       :                 .:     *    .        *   *:..

TH_2496|M.thermoresistible__bu      DAVLSGLLGMTDDEIAALREQGAIGPAYN--------
MSMEG_4834|M.smegmatis_MC2_155      DHILAD-IGLSAEEIASLREQGAVGPAMQTRSEQSHA
Mflv_2443|M.gilvum_PYR-GCK          DAVLTE-FGVSAEELAQLRAEGAIGPAYRG-------
Mvan_4208|M.vanbaalenii_PYR-1       DAVLTE-IGVTPDELRQLRADGAIGPAYRG-------
MAV_2651|M.avium_104                RKILHE-LGYSAQATDELIAAGVTTA-----------
Mb3300|M.bovis_AF2122/97            -AVFLARP-----------------------------
Rv3272|M.tuberculosis_H37Rv         -AVFLARP-----------------------------
MMAR_1494|M.marinum_M               DDVYIGLLGKSIEELEQLRAEEVL-------------
MUL_2446|M.ulcerans_Agy99           DDVYIGLLGKSIEELEQLRAVEVL-------------
MAB_4651c|M.abscessus_ATCC_199      DDVYVGLLGKSAQDIERLRAEGVL-------------
                                      :