For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GPLSGVTVVSLEQAVAAPYATRQLADLGARVIKVERPDGGDFARGYDHSVHGDSSYFVWLNRGKESLTLD LKTLEGQRILRQLLANSDVLVQNLGPGATTRLSLDATTLTPEYPRLIVCDITGYGGTGPWRDRKAYDLLV QAEAGLLSVTGSGDEVARTGVSIADIAAGMFAFSGILTALYVRATTGDVRPVSVSLFESLVELVSQPAYY AHYGGTAPPRTGARHATIAPYGPFTAGDGGTVLLAVQNQREWRRLCDEVLATPGLCEDPRFVTNPDRVTH RDELEAIIHAAIASMTADELAHRLEAAGIANARMNDVETLWSHPVLAGRDRWREVRAPGGAIEALLPPAT LRDVEPQLGDVPGLAAHSRMILRELGYTNEAIADLVRSGVTTVASDH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1892 | - | - | 100% (398) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_2651 | - | e-156 | 70.83% (384) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_4024 | - | 1e-43 | 32.24% (397) | caib/baif family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 1e-35 | 30.49% (387) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2443 | - | 6e-92 | 44.81% (395) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 8e-36 | 30.49% (387) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 2e-51 | 36.96% (368) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 6e-43 | 34.17% (319) | hypothetical protein MMAR_1494 |
| M. smegmatis MC2 155 | MSMEG_1992 | - | 1e-122 | 58.58% (379) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_2496 | - | 2e-92 | 45.43% (394) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_2446 | - | 7e-43 | 34.17% (319) | hypothetical protein MUL_2446 |
| M. vanbaalenii PYR-1 | Mvan_4208 | - | 4e-90 | 44.92% (394) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1494|M.marinum_M -----MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPD
MUL_2446|M.ulcerans_Agy99 -----MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPD
MAB_0824|M.abscessus_ATCC_1997 ------MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGD
Mb3300|M.bovis_AF2122/97 --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEA
Rv3272|M.tuberculosis_H37Rv --MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEA
MAV_1892|M.avium_104 MG--------PLSGVTVVSLEQAVAAPYATRQLADLGARVIKVERPDGGD
MSMEG_1992|M.smegmatis_MC2_155 MHPQANGKSLPLSGITVLSLEHAVAAPFATRQLADLGARVIKVERPGSGD
Mflv_2443|M.gilvum_PYR-GCK -MTASQ-SAGPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
Mvan_4208|M.vanbaalenii_PYR-1 -MSSSQPSAAPLAGVTVVAMEQAVAAPMCTRVLADFGARIIKVENPNGGD
TH_2496|M.thermoresistible__bu MAESEHADPAPLAGITVVALEQAVSAPMCTRVLADFGARVIKVENPDGGD
.* *. *: : ::.* . * *:** :**:* *
MMAR_1494|M.marinum_M PLRTWG-QAEVDG-HHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSD
MUL_2446|M.ulcerans_Agy99 PLRTWG-QAEVDG-HHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSD
MAB_0824|M.abscessus_ATCC_1997 DTRQWGPPYDSDG-QATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRAD
Mb3300|M.bovis_AF2122/97 ARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
Rv3272|M.tuberculosis_H37Rv ARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTAD
MAV_1892|M.avium_104 FARGYDHSVHG---DSSYFVWLNRGKESLTLDLKTLEGQRILRQLLANSD
MSMEG_1992|M.smegmatis_MC2_155 FARQYDDSVNG---ESSYFVWLNRSKESIALDVKSEHGHRVLHELADRAD
Mflv_2443|M.gilvum_PYR-GCK FARAYDDVVNGPGGLAAHFVWSNRGKESVTLNTKSPAGLEVLHRLLDRAD
Mvan_4208|M.vanbaalenii_PYR-1 FARDYDDVVNGPGGLAAHFVWSNRGKESVTLNTKTAGGLDLLHRLLDRAD
TH_2496|M.thermoresistible__bu FARHYDDVVKG---QAAHFVWANRGKESVTLNLKSEAGMAVLHRLLDEAD
: . .: *.*.::.:: . .* :*
MMAR_1494|M.marinum_M IVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYAS
MUL_2446|M.ulcerans_Agy99 IVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYAS
MAB_0824|M.abscessus_ATCC_1997 VVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLPGYDL
Mb3300|M.bovis_AF2122/97 VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
Rv3272|M.tuberculosis_H37Rv VVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDL
MAV_1892|M.avium_104 VLVQNLGPGATTRLSLDATTLTPEYPRLIVCDITGYGGTGPWRDRKAYDL
MSMEG_1992|M.smegmatis_MC2_155 VVVQNLGPGAAARLGLAAEDIRAKDPRKIVVSVTGWGSTGPWADRKAYDL
Mflv_2443|M.gilvum_PYR-GCK AFVSNLAPGATARLGLSPADLAERHPQVIPVEIDGYGPGGPISHKRAYDL
Mvan_4208|M.vanbaalenii_PYR-1 AFVSNLAPGATARLGVAPADLAARHPRVIPVEIDGYGPGGPLSHKRAYDL
TH_2496|M.thermoresistible__bu VLVSNLAPGALARMGLAADDLKTSHPRVLPVQIDGYGAGGPISHKRAYDL
.:. : .*: : .: : * : : .:* *. .
MMAR_1494|M.marinum_M VAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRRSVT-
MUL_2446|M.ulcerans_Agy99 VAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGPQGALAALYRRSVT-
MAB_0824|M.abscessus_ATCC_1997 LVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRT-
Mb3300|M.bovis_AF2122/97 VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
Rv3272|M.tuberculosis_H37Rv VVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERN-
MAV_1892|M.avium_104 LVQAEAGLLSVTGSG-DEVARTGVSIADIAAGMFAFSGILTALYVRATT-
MSMEG_1992|M.smegmatis_MC2_155 LVQCETGLVSLTGTP-DEVAKVGVSIADIAAGMYAFSGILAALYRREIT-
Mflv_2443|M.gilvum_PYR-GCK LVQAESGSCAVTGYP-GMPAKPGPAVADFTSGLYAAMSIVSLLYGRATR-
Mvan_4208|M.vanbaalenii_PYR-1 LVQAESGSCAVTGYP-GMPAKPGPAVADFSTGLYAAISILALLYGRARH-
TH_2496|M.thermoresistible__bu LIQAESGACAVTGYP-GMPAKPGPPVADISTGLYAALSVMALLYGRDRRD
: . * : * :. . :: * *
MMAR_1494|M.marinum_M ----GTGQVVDVALTESCLALQESTISDYDVGGVVRGPS------GTRLE
MUL_2446|M.ulcerans_Agy99 ----GTGQVVDVALTESCLALQESTISDYDVGGVVRGPS------GTRLK
MAB_0824|M.abscessus_ATCC_1997 ----GQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEAL------GNRHP
Mb3300|M.bovis_AF2122/97 ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
Rv3272|M.tuberculosis_H37Rv ----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRK
MAV_1892|M.avium_104 ----GDVRPVSVSLFESLVELVSQPAYYAHYGGTAPPRT------GARHA
MSMEG_1992|M.smegmatis_MC2_155 ----GEGAVIEVSLFEALAEWVGQPAHFTAGAGRQPGRF------GAQHA
Mflv_2443|M.gilvum_PYR-GCK -PEPGPAPHVELSLFDVMTDVMGYALTYTQHSGIDQEPL------GVGSP
Mvan_4208|M.vanbaalenii_PYR-1 -PGSAPAPSVELSLFDVMTDVMGYALTYTQHSGIDQEPL------GVGSP
TH_2496|M.thermoresistible__bu RATPGPVPAVAVSLFDTMTDIMGYQLTYTQHSGVDQQPL------GMSSP
. : : . . .
MMAR_1494|M.marinum_M GI----APSNIYRSADESWVVIAANQDTVFTRLCQAMG-CPELATDDRFA
MUL_2446|M.ulcerans_Agy99 GI----APSNIYRSADESWVVIAANQDTVFTRLCQAMG-CPELATDDRFA
MAB_0824|M.abscessus_ATCC_1997 SI----APYQTFETADR-PIAIAVGNDKQFRLLVQALE-MPRLARDDRFA
Mb3300|M.bovis_AF2122/97 GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
Rv3272|M.tuberculosis_H37Rv GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIG-RPDLVEDQRFA
MAV_1892|M.avium_104 TI----APYGPFTAGDGGTVLLAVQNQREWRRLCDEVLATPGLCEDPRFV
MSMEG_1992|M.smegmatis_MC2_155 TI----APYGPFEAADGHTLLIAIQNEPEWARFCTTVLGRPEVAEDPRFA
Mflv_2443|M.gilvum_PYR-GCK AV----APYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
Mvan_4208|M.vanbaalenii_PYR-1 AV----APYGAFPTRDGQTVVLGTTNDREWQRVAREIIDRPDLADDPRFA
TH_2496|M.thermoresistible__bu AV----APYGAFRTRDGQTVVLGTTNDREWQRLARDIIERPDLADDPAYA
: * : : * : :. : . : * : * :.
MMAR_1494|M.marinum_M THRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVK
MUL_2446|M.ulcerans_Agy99 THRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVK
MAB_0824|M.abscessus_ATCC_1997 TNPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFR
Mb3300|M.bovis_AF2122/97 EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
Rv3272|M.tuberculosis_H37Rv EQRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVD
MAV_1892|M.avium_104 TNPDRVTHRDELEAIIHAAIASMTADELAHRLEAAGIANARMNDVETLWS
MSMEG_1992|M.smegmatis_MC2_155 SNTQRVANRADVNALISEVFSSHPTDELESRLTEARIAFAGVNTVSEFLD
Mflv_2443|M.gilvum_PYR-GCK TNPGRCANRDVLEEAIGAWCARHDLAEIQDKADRAGIGNSRYNLPSEVIA
Mvan_4208|M.vanbaalenii_PYR-1 TNSDRCAHRQILEEAIGSWCAQHDLAEIQKTADAAGIGNSRYNLPSEVVV
TH_2496|M.thermoresistible__bu TNSDRVRHRDVLNEAIAAWCARHDLAHIQKTADDAGIGNSRYNLPSEVVA
: * : : : . : :
MMAR_1494|M.marinum_M DRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHN
MUL_2446|M.ulcerans_Agy99 DRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHN
MAB_0824|M.abscessus_ATCC_1997 FAERLGLDVAVTVPGSPE-PQVANP---ISMSKTP-VVYRNGPPRLGQSR
Mb3300|M.bovis_AF2122/97 TPLFAESDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEHN
Rv3272|M.tuberculosis_H37Rv TPLFAENDLTLEVGRGADTITVIRT---PARYASFRAVVTDPPPTAGEHN
MAV_1892|M.avium_104 HPVLAGRDRWREVRAPGGAIEALLP----PATLRDVEPQLGDVPGLAAHS
MSMEG_1992|M.smegmatis_MC2_155 HPVLAARDRWRSVETENGPVRALLP----PLDLG-TEVRMDPVPALGAHT
Mflv_2443|M.gilvum_PYR-GCK HPHLVARDRWRTVATPKGDIQALRP----PPVISDFEQPMGAIPGLGEHT
Mvan_4208|M.vanbaalenii_PYR-1 HPHLAARDRWRTVATPKGDIQALRP----PPVISDFEQPMGAIPGLGEHT
TH_2496|M.thermoresistible__bu HPHLSARDRWRPVDTPNGQITALRP----PPVIEGFEQPMGPVPGLGQHT
. . . . . .
MMAR_1494|M.marinum_M DDVYIGLLGKSIEELEQLRAEEVL------
MUL_2446|M.ulcerans_Agy99 DDVYIGLLGKSIEELEQLRAVEVL------
MAB_0824|M.abscessus_ATCC_1997 A-----------------------------
Mb3300|M.bovis_AF2122/97 AVFLARP-----------------------
Rv3272|M.tuberculosis_H37Rv AVFLARP-----------------------
MAV_1892|M.avium_104 RMILR-ELGYTNEAIADLVRSGVTTVASDH
MSMEG_1992|M.smegmatis_MC2_155 AAILA-ELGHGDD-----------------
Mflv_2443|M.gilvum_PYR-GCK DAVLT-EFGVSAEELAQLRAEGAIGPAYRG
Mvan_4208|M.vanbaalenii_PYR-1 DAVLT-EIGVTPDELRQLRADGAIGPAYRG
TH_2496|M.thermoresistible__bu DAVLSGLLGMTDDEIAALREQGAIGPAYN-