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RHSRAEKKLHTRRTLLDGTLELLKVRGFAAVSLREVAKSAGLVPTAFYRHFESMEDLGTVLAEESVHALR DTFRQARREAGSDNPAKILRLMVDRVNEHANNFRFLVRERHGGSPQIRRAINNEMRMLTNDVVVELARNP ATNHHTTEDLEIAAELIASSILNTIGMLVDTDHPTKADADAALNRALRQLDLVTSGLAHTRTMTTIIAEP AARPSESSATTAAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1424c | - | - | 100% (225) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1589 | - | 5e-34 | 40.33% (181) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2061c | - | 7e-07 | 27.48% (131) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3084c | - | 2e-06 | 24.32% (185) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4816 | - | 6e-37 | 41.18% (204) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3058c | - | 2e-06 | 24.32% (185) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0334 | - | 5e-35 | 41.79% (201) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5169 | - | 8e-35 | 39.02% (205) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1741 | - | 3e-35 | 40.50% (200) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0865 | - | 9e-08 | 25.79% (159) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4787 | - | 1e-34 | 40.80% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1626 | - | 1e-34 | 40.49% (205) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
Mvan_1626|M.vanbaalenii_PYR-1 ----------------MNSRTPSSRSGRS-RSREKD-----TLSREERKE
MSMEG_1741|M.smegmatis_MC2_155 ----------------MNRRTPSTRTRRSETSRSRD-----TLTREERKE
MMAR_0334|M.marinum_M ----------------MNERTPSSRPHRSGRSRDSP-------SREERKE
MUL_4787|M.ulcerans_Agy99 ----------------MNERTPSSRPHRSSRSRDSP-------SREERKE
MAV_5169|M.avium_104 -----------------------MRGSGRERSRESQ-------SREERKE
MAB_1424c|M.abscessus_ATCC_199 -----------------------MR-----------------HSRAEKKL
Mb3084c|M.bovis_AF2122/97 -----------------------MTSHAADEKQAAP-------PMRRRGD
Rv3058c|M.tuberculosis_H37Rv -----------------------MTSHAADEKQAAP-------PMRRRGD
TH_0865|M.thermoresistible__bu --------------------VGQQTPPAAVKMDGRK------RRWHQHKV
.:
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
Mvan_1626|M.vanbaalenii_PYR-1 ATRRAIVAAALSLLAERSFSGLSLREVTREAGIVPAAFYRHFESMEALGL
MSMEG_1741|M.smegmatis_MC2_155 ATRRALIAAALKLLKDHSFSALSLREVTREAGIVPAAFYRHFDSMDALGL
MMAR_0334|M.marinum_M ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MUL_4787|M.ulcerans_Agy99 ATRRAIIAAALKLVHDRSFSALSLREVTREAGIVPAAFYRHFESMEALGL
MAV_5169|M.avium_104 ATRRAIIAAALKLLQDRSFSSLSLREVTREVGIVPAAFYRHFESMESLGL
MAB_1424c|M.abscessus_ATCC_199 HTRRTLLDGTLELLKVRGFAAVSLREVAKSAGLVPTAFYRHFESMEDLGT
Mb3084c|M.bovis_AF2122/97 RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLA
Rv3058c|M.tuberculosis_H37Rv RHRQAILRAARELLEETPFAELSVRAISLRAGVARSGFYFYFDSKYSVLA
TH_0865|M.thermoresistible__bu ERRNELVDGTLEAIRRRG-SNVSMDEIAAEIGVSKTVLYRYFVDKNDLTT
*. :: .: : : :*: :: *: : :* :* . :
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRGAR--AGKLDPNRVIESSVDILIDGVQQRREHWRF
Mvan_1626|M.vanbaalenii_PYR-1 VLIDESFRALREMLRGAR--AGKLDPNRVIESSVDILIDSVQQRREHWRF
MSMEG_1741|M.smegmatis_MC2_155 VLIDESFRSLRDMLRGAR--AGKLDPHHVIESSAEILVSSFNERREHWRF
MMAR_0334|M.marinum_M VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWRF
MUL_4787|M.ulcerans_Agy99 VLIDESFRTLRDTLRGAR--AGRLDPNRVIESSVEILIGSVAERREHWRF
MAV_5169|M.avium_104 VLIDESFRSLRDTLRDAR--AGKLDPNRVIESSVEILVASVADRREHWRL
MAB_1424c|M.abscessus_ATCC_199 VLAEESVHALRDTFRQARREAGSDNPAKILR----LMVDRVNEHANNFRF
Mb3084c|M.bovis_AF2122/97 QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
Rv3058c|M.tuberculosis_H37Rv QILAEATEELEEASQHFSARQPGESPEQFVNRMIGSVAAVYANNDPVLRA
TH_0865|M.thermoresistible__bu AVMMR-FAQTTLIPNMAAALSTDLDGYDLTREIIRVYVETVAAEPEPYRF
: . . . . . . *
Mflv_4816|M.gilvum_PYR-GCK IGRERSTGVT-VLRYAIRTEIRLITSELAIDLAR----------------
Mvan_1626|M.vanbaalenii_PYR-1 IGRERSTGVT-VLRYAIRTEIRLITSELAIDLAR----------------
MSMEG_1741|M.smegmatis_MC2_155 IARERSGGAS-ALRYAIRTEIRLITSELAIDLAR----------------
MMAR_0334|M.marinum_M IVRERSTGLS-VLRYAIRTEIRLITSELATDLAR----------------
MUL_4787|M.ulcerans_Agy99 IVRERSTGLS-VLRYAIRTDIRLITSELATDLAR----------------
MAV_5169|M.avium_104 IARERNSGLS-VLRYAIRTEIRLITSELATDLAR----------------
MAB_1424c|M.abscessus_ATCC_199 LVRERHGGSP-QIRRAINNEMRMLTNDVVVELAR----------------
Mb3084c|M.bovis_AF2122/97 CNAARQSDME-IRDILERQFQVLLRETIGVFEAE----------------
Rv3058c|M.tuberculosis_H37Rv CNAARQSDME-IRDILERQFQVLLRETIGVFEAE----------------
TH_0865|M.thermoresistible__bu VMANNSAGKSKVVADSERIIARMLGVMLRRRMAEAGMDTRGVEPWSNLIV
. . . :: : *.
Mflv_4816|M.gilvum_PYR-GCK ------------FPA-LNTWSSEDLNILASVFVNSMIAIAEQLE---DVT
Mvan_1626|M.vanbaalenii_PYR-1 ------------FPN-LNTWSSEDLNILASVFVNSMIVIAESLE---DAT
MSMEG_1741|M.smegmatis_MC2_155 ------------FPA-LKDWSSEDLNILANLFVNSMISLAEALE---DAA
MMAR_0334|M.marinum_M ------------FPG-LNEWSTEDLNILATLFVNAMIVTAEAIE---DAQ
MUL_4787|M.ulcerans_Agy99 ------------FPG-LNEWSTEDLNILATMFVNAMIVTAEAIE---DAQ
MAV_5169|M.avium_104 ------------FPG-LHEWTTEDLNVLATLFVNAMIVIAEAIE---DSQ
MAB_1424c|M.abscessus_ATCC_199 ------------NPA-TNHHTTEDLEIAAELIASSILNTIGMLV---DTD
Mb3084c|M.bovis_AF2122/97 ------------VKAGTAHPISEDLPTLVRTLAATTALMLTGDA---LLV
Rv3058c|M.tuberculosis_H37Rv ------------VKAGTAHPISEDLPTLVRTLAATTALMLTGDA---LLV
TH_0865|M.thermoresistible__bu GGVQLATHSWMSHPRMTSDELIDYLTMLSWSALCGIVEVGGSLEKFREMP
: *
Mflv_4816|M.gilvum_PYR-GCK DT------------------ASVDEIRRTAVKQLRMITVGVAGWRSG---
Mvan_1626|M.vanbaalenii_PYR-1 DP------------------ASIAEIRRIAIKQLRMITVGVAGWRSS---
MSMEG_1741|M.smegmatis_MC2_155 DA------------------ESIEAIHRTAVKQMRMIAVGVNGWRSTD--
MMAR_0334|M.marinum_M SS------------------EALEEIRRIAVKQLRMVAIGVAGWKSRP--
MUL_4787|M.ulcerans_Agy99 SS------------------EALEEIRRIAVKQLRMVAIGVAGWKSRP--
MAV_5169|M.avium_104 SA------------------EAREDIRRLAVKQLRMIATGIAGWRSTP--
MAB_1424c|M.abscessus_ATCC_199 HPTK----------------ADADAALNRALRQLDLVTSGLAHTRTMTTI
Mb3084c|M.bovis_AF2122/97 GP-------------------DSDAARRVRVLEQMWLNALWGGGKAP---
Rv3058c|M.tuberculosis_H37Rv GP-------------------DSDAARRVRVLEQMWLNALWGGGKAP---
TH_0865|M.thermoresistible__bu HPSXXSSSLSGNGLNSPQPWGPSISMPSRTAAPPDIPTVGIANSGAVSKS
. :
Mflv_4816|M.gilvum_PYR-GCK -------------------------------
Mvan_1626|M.vanbaalenii_PYR-1 -------------------------------
MSMEG_1741|M.smegmatis_MC2_155 -------------------------------
MMAR_0334|M.marinum_M -------------------------------
MUL_4787|M.ulcerans_Agy99 -------------------------------
MAV_5169|M.avium_104 -------------------------------
MAB_1424c|M.abscessus_ATCC_199 IAEPAARPSESSATTAAP-------------
Mb3084c|M.bovis_AF2122/97 -------------------------------
Rv3058c|M.tuberculosis_H37Rv -------------------------------
TH_0865|M.thermoresistible__bu ISVCTERKLADRARKRPEPGIRPGTRNRRRS