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QPVPEASKAGSSSQRRAGRREELVAVASKLFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIY FKAAEETLACLQDDPRWSARESLYQCTSRMLALIFSNREQGAVYFQENPFLSEWLSPEQVAEIRTREDMV QERVQNIIERGIASGEFVECDSHVMALGYIGMVLGSYRWLNPSGRRSAQEIAVEFSTTLLRGLIRDEATR INDPLGVASATSLDGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4574c | - | - | 100% (228) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0599 | - | 1e-15 | 30.20% (202) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 7e-12 | 25.73% (206) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0163 | - | 6e-81 | 68.10% (210) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0719 | - | 4e-75 | 68.34% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0158 | - | 7e-81 | 68.10% (210) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-10 | 26.56% (192) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0381 | - | 2e-78 | 68.14% (204) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5138 | - | 1e-78 | 68.27% (208) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0120 | - | 7e-74 | 63.29% (207) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0160 | - | 4e-74 | 65.84% (202) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4731 | - | 1e-78 | 68.14% (204) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0126 | - | 1e-74 | 65.53% (206) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0163|M.bovis_AF2122/97 ---------------------------MPSDTS-PNGLSRREELLAVATK
Rv0158|M.tuberculosis_H37Rv ---------------------------MPSDTS-PNGLSRREELLAVATK
MMAR_0381|M.marinum_M ---------------------------MPSET----GLSRREELLAVATK
MUL_4731|M.ulcerans_Agy99 ---------------------------MPSET----GLSRREELLAVATK
MAV_5138|M.avium_104 ---------------------------MPADSSTPNGQTRREELLAVATK
Mflv_0719|M.gilvum_PYR-GCK -------------------------------------MSRREELLAVATK
Mvan_0126|M.vanbaalenii_PYR-1 ---------------------------MSESTT--NGMSRREELLAVATK
MSMEG_0120|M.smegmatis_MC2_155 ---------------------------MTSAAN--NGTSRREELLNVAAK
TH_0160|M.thermoresistible__bu -------------------------------------MTRREELLAVATR
MAB_4574c|M.abscessus_ATCC_199 --------------------MQPVPEASKAGSSSQRRAGRREELVAVASK
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
** :*: **:
Mb0163|M.bovis_AF2122/97 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
Rv0158|M.tuberculosis_H37Rv LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
MMAR_0381|M.marinum_M LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MUL_4731|M.ulcerans_Agy99 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MAV_5138|M.avium_104 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILYDIYQQAAERTLA
Mflv_0719|M.gilvum_PYR-GCK LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
Mvan_0126|M.vanbaalenii_PYR-1 LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
MSMEG_0120|M.smegmatis_MC2_155 LFAARGYHGTRMDDVAEAVGLNKATVYHYYASKSLILYDIYKSAADFTVE
TH_0160|M.thermoresistible__bu LFAARGYHGTRMDDVADAIGLNKATVYHYYASKSLILYDIYRRAADSTVA
MAB_4574c|M.abscessus_ATCC_199 LFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIYFKAAEETLA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
:*. :***.: **::*: *:.*..:*::::** : : : :
Mb0163|M.bovis_AF2122/97 AVHDDP--SWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
Rv0158|M.tuberculosis_H37Rv AVHDDP--SWTAREALYQYTVRLLTAIASNPERAAVYFQEQPYITEWFTS
MMAR_0381|M.marinum_M ALHAEP--SWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTP
MUL_4731|M.ulcerans_Agy99 ALHAEP--SWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTP
MAV_5138|M.avium_104 AVHDDP--SMTAREALYQYTVRLLDQIAANPEGAAVYFQEQPYITEWFTK
Mflv_0719|M.gilvum_PYR-GCK ALHDDP--TASARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTE
Mvan_0126|M.vanbaalenii_PYR-1 ALHDDP--TATARETIYHFTRRLLVGIANDIERAAVYFQEGPYITEWFTE
MSMEG_0120|M.smegmatis_MC2_155 ALHDDP--TSSARETIYHFTRRLMVGIANDLERAAVYFQEGPYIAEWFTE
TH_0160|M.thermoresistible__bu ALHDDP--NASAREMIYEFTRRLLVGIAGDIERAAVYFQEAPYITEWFTE
MAB_4574c|M.abscessus_ATCC_199 CLQDDP--RWSARESLYQCTSRMLALIFSNREQGAVYFQENPFLSEWLSP
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEND----NITEP
.:: . *: :: . :: * : : : *:: :
Mb0163|M.bovis_AF2122/97 EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
Rv0158|M.tuberculosis_H37Rv EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
MMAR_0381|M.marinum_M EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
MUL_4731|M.ulcerans_Agy99 EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSY
MAV_5138|M.avium_104 EQVAAVREKETQVYEHVHGLIDRGIASGEFYECDSHVLALGYIGMTLGAY
Mflv_0719|M.gilvum_PYR-GCK EQVDYIREKEAQVYEHVRDVIDRGIASGEFNDCDSHVLALGYIGMTLGSY
Mvan_0126|M.vanbaalenii_PYR-1 EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGSY
MSMEG_0120|M.smegmatis_MC2_155 EQVEYIRHSEAQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMVLGAY
TH_0160|M.thermoresistible__bu EQVAYIRESEAKVYEHVRDVIDRGIASGEFYECDSHVLALGYIGMTLGSY
MAB_4574c|M.abscessus_ATCC_199 EQVAEIRTREDMVQERVQNIIERGIASGEFVECDSHVMALGYIGMVLGSY
MLBr_00815|M.leprae_Br4923 RVAAQVRVATESCIDAVFALIS---ADSRLDPHRARMVAVGLVGISVDCA
. . :* : * :*. *...: ::::*:* :*: :..
Mb0163|M.bovis_AF2122/97 RWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET------
Rv0158|M.tuberculosis_H37Rv RWLRPSGRRTAKEIAAEFSTALLRGLIRDESIRNQSPLGTRKET------
MMAR_0381|M.marinum_M RWLRPHGRRTAREIAAEFSTALLRGLIRDESIRNQSPLGS----------
MUL_4731|M.ulcerans_Agy99 RWLRPHGRRTAREIAAEFSTALLRGLIRDESIRNQSPLGS----------
MAV_5138|M.avium_104 RWLRPSGRRSAKEIAAEFSTALLRGLIRDEEIRTTSPLGP----------
Mflv_0719|M.gilvum_PYR-GCK RWLRPHGRRTAQEIAVEFSSALLRGLIRDETVRATSPLGVGIDVTAKQ--
Mvan_0126|M.vanbaalenii_PYR-1 RWLRPHGRRTAQEIAVEFSTALLRGLIRDETVRTLSPLGVGIDAPVKTRI
MSMEG_0120|M.smegmatis_MC2_155 RWLRPHGRRTAKEIAVEFSTALLRGLIRDENIRVESPLGIDVQAGSEEQR
TH_0160|M.thermoresistible__bu RWLRPDGRRTAEEIAEEFSTALLRGLIRDEKIRADFPHGTGESEAEPANP
MAB_4574c|M.abscessus_ATCC_199 RWLNPSGRRSAQEIAVEFSTTLLRGLIRDEATRINDPLGVASATSLDGAR
MLBr_00815|M.leprae_Br4923 RYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL---------------
*: .* :.. * * : : * : .
Mb0163|M.bovis_AF2122/97 -----
Rv0158|M.tuberculosis_H37Rv -----
MMAR_0381|M.marinum_M -----
MUL_4731|M.ulcerans_Agy99 -----
MAV_5138|M.avium_104 -----
Mflv_0719|M.gilvum_PYR-GCK -----
Mvan_0126|M.vanbaalenii_PYR-1 LEEPS
MSMEG_0120|M.smegmatis_MC2_155 -----
TH_0160|M.thermoresistible__bu AG---
MAB_4574c|M.abscessus_ATCC_199 -----
MLBr_00815|M.leprae_Br4923 -----