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M. gilvum PYR-GCK Mflv_0719 (-)

annotation: TetR family transcriptional regulator
coordinates: 738769 - 739398
length: 209

SRREELLAVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTA
SARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDYIREKEAQVYEHVRDVIDRGIASGEF
NDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEFSSALLRGLIRDETVRATSPLGVGIDVTAKQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0719--100% (209)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_1483-5e-1425.79% (190) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0013-7e-1047.27% (55) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0163-3e-8878.00% (200) TetR family transcriptional regulator
M. tuberculosis H37RvRv0158-3e-8878.00% (200) TetR family transcriptional regulator
M. leprae Br4923MLBr_00717-5e-0834.78% (69) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4574c-3e-7568.34% (199) TetR family transcriptional regulator
M. marinum MMMAR_0381-2e-8878.00% (200) TetR family transcriptional regulator
M. avium 104MAV_5138-6e-8777.39% (199) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_0120-1e-10385.10% (208) transcriptional regulatory protein
M. thermoresistible (build 8)TH_0160-9e-9886.14% (202) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY
M. ulcerans Agy99MUL_4731-2e-8878.00% (200) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0126-1e-11294.23% (208) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0719|M.gilvum_PYR-GCK          -----------------MSRREELLAVATKLFAARGYHGTRMDDVADAVG
Mvan_0126|M.vanbaalenii_PYR-1       -------MSESTT--NGMSRREELLAVATKLFAARGYHGTRMDDVADAVG
MSMEG_0120|M.smegmatis_MC2_155      -------MTSAAN--NGTSRREELLNVAAKLFAARGYHGTRMDDVAEAVG
TH_0160|M.thermoresistible__bu      -----------------MTRREELLAVATRLFAARGYHGTRMDDVADAIG
Mb0163|M.bovis_AF2122/97            -------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIG
Rv0158|M.tuberculosis_H37Rv         -------MPSDTS-PNGLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MMAR_0381|M.marinum_M               -------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MUL_4731|M.ulcerans_Agy99           -------MPSET----GLSRREELLAVATKLFAARGYHGTRMDDVADVIG
MAV_5138|M.avium_104                -------MPADSSTPNGQTRREELLAVATKLFAARGYHGTRMDDVADVIG
MAB_4574c|M.abscessus_ATCC_199      MQPVPEASKAGSSSQRRAGRREELVAVASKLFAARGYHGTRMDDIADVAG
MLBr_00717|M.leprae_Br4923          -------MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAG
                                                       ** **: :.:.:*. * *. .*:*::*:  *

Mflv_0719|M.gilvum_PYR-GCK          LNKATVYHYYASKSLILYDIYKGAADFTVDALHDDP--TASARETIYHFT
Mvan_0126|M.vanbaalenii_PYR-1       LNKATVYHYYASKSLILYDIYKGAADFTVDALHDDP--TATARETIYHFT
MSMEG_0120|M.smegmatis_MC2_155      LNKATVYHYYASKSLILYDIYKSAADFTVEALHDDP--TSSARETIYHFT
TH_0160|M.thermoresistible__bu      LNKATVYHYYASKSLILYDIYRRAADSTVAALHDDP--NASAREMIYEFT
Mb0163|M.bovis_AF2122/97            LNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDP--SWTAREALYQYT
Rv0158|M.tuberculosis_H37Rv         LNKATVYHYYASKSLILFDIYRQAAEGTLAAVHDDP--SWTAREALYQYT
MMAR_0381|M.marinum_M               LNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEP--SWTAREALYQYT
MUL_4731|M.ulcerans_Agy99           LNKATVYHYYASKSLILFDIYRQAAEGTLGALHAEP--SWTAREALYQYT
MAV_5138|M.avium_104                LNKATVYHYYASKSLILYDIYQQAAERTLAAVHDDP--SMTAREALYQYT
MAB_4574c|M.abscessus_ATCC_199      LNKATVYHYFASKALILYEIYFKAAEETLACLQDDP--RWSARESLYQCT
MLBr_00717|M.leprae_Br4923          VSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGV
                                    :.:* :***:..*  ::  :    *:    . :  *    :  * :   .

Mflv_0719|M.gilvum_PYR-GCK          RRLLVGIASDIERAAVYFQEGPYISEWFTEEQVDYIREKEAQVYEHVRDV
Mvan_0126|M.vanbaalenii_PYR-1       RRLLVGIANDIERAAVYFQEGPYITEWFTEEQVEYIREKETQVYEHVRDV
MSMEG_0120|M.smegmatis_MC2_155      RRLMVGIANDLERAAVYFQEGPYIAEWFTEEQVEYIRHSEAQVYEHVRDV
TH_0160|M.thermoresistible__bu      RRLLVGIAGDIERAAVYFQEAPYITEWFTEEQVAYIRESEAKVYEHVRDV
Mb0163|M.bovis_AF2122/97            VRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGL
Rv0158|M.tuberculosis_H37Rv         VRLLTAIASNPERAAVYFQEQPYITEWFTSEQVAEVREKEQQVYEHVHGL
MMAR_0381|M.marinum_M               VRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHVHGL
MUL_4731|M.ulcerans_Agy99           VRLLTGIADNPERAAVYFQEQPYIAEWFTPEQVAEVREKEAQVHEHVHGL
MAV_5138|M.avium_104                VRLLDQIAANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQVYEHVHGL
MAB_4574c|M.abscessus_ATCC_199      SRMLALIFSNREQGAVYFQENPFLSEWLSPEQVAEIRTREDMVQERVQNI
MLBr_00717|M.leprae_Br4923          LAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDV
                                       :     : * . . :         :   :    .     : .:: .:

Mflv_0719|M.gilvum_PYR-GCK          IDRGIAS--GEFNDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEF
Mvan_0126|M.vanbaalenii_PYR-1       IDRGIAS--GEFYDCDSHVLALGYIGMTLGSYRWLRPHGRRTAQEIAVEF
MSMEG_0120|M.smegmatis_MC2_155      IDRGIAS--GEFYDCDSHVLALGYIGMVLGAYRWLRPHGRRTAKEIAVEF
TH_0160|M.thermoresistible__bu      IDRGIAS--GEFYECDSHVLALGYIGMTLGSYRWLRPDGRRTAEEIAEEF
Mb0163|M.bovis_AF2122/97            IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF
Rv0158|M.tuberculosis_H37Rv         IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKEIAAEF
MMAR_0381|M.marinum_M               IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAEF
MUL_4731|M.ulcerans_Agy99           IDRGIAS--GEFYECDSHVVALGYIGMTLGSYRWLRPHGRRTAREIAAEF
MAV_5138|M.avium_104                IDRGIAS--GEFYECDSHVLALGYIGMTLGAYRWLRPSGRRSAKEIAAEF
MAB_4574c|M.abscessus_ATCC_199      IERGIAS--GEFVECDSHVMALGYIGMVLGSYRWLNPSGRRSAQEIAVEF
MLBr_00717|M.leprae_Br4923          VSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSC
                                    :.    *      : * :*:. *::.:.:   *         * .:* . 

Mflv_0719|M.gilvum_PYR-GCK          SSALLRGLIRDETVRATSPLGVGIDVTAKQ-------
Mvan_0126|M.vanbaalenii_PYR-1       STALLRGLIRDETVRTLSPLGVGIDAPVKTRILEEPS
MSMEG_0120|M.smegmatis_MC2_155      STALLRGLIRDENIRVESPLGIDVQAGSEEQR-----
TH_0160|M.thermoresistible__bu      STALLRGLIRDEKIRADFPHGTGESEAEPANPAG---
Mb0163|M.bovis_AF2122/97            STALLRGLIRDESIRNQSPLGTRKET-----------
Rv0158|M.tuberculosis_H37Rv         STALLRGLIRDESIRNQSPLGTRKET-----------
MMAR_0381|M.marinum_M               STALLRGLIRDESIRNQSPLGS---------------
MUL_4731|M.ulcerans_Agy99           STALLRGLIRDESIRNQSPLGS---------------
MAV_5138|M.avium_104                STALLRGLIRDEEIRTTSPLGP---------------
MAB_4574c|M.abscessus_ATCC_199      STTLLRGLIRDEATRINDPLGVASATSLDGAR-----
MLBr_00717|M.leprae_Br4923          AHALLDAIARVPEISKELADAMAIARQPPQ-------
                                    : :** .: *        . .