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VTETPVRRRRADAQRNRDAILRAAREAFETDGIFAPLDSIATAAGVGNATLYRNFPTRDDLLRAVLEDGV AEMVAESEAYERHSDAEEALRDWLFRVTWALRIWHDLPNCIATAHDDAESPVRPVTDRMTDRTARLLDNY RAGKGPSPVTAEELFQLVTAVSWAVDRFGDDRDRARRRLEFATSGLFDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1596 | - | - | 100% (189) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 1e-17 | 37.75% (151) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1380 | - | 9e-15 | 29.57% (186) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 9e-14 | 41.67% (84) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 5e-12 | 50.00% (64) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 9e-14 | 41.67% (84) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 4e-15 | 44.44% (90) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 7e-15 | 40.22% (92) | transcriptional regulator TetR |
| M. marinum M | MMAR_1637 | - | 2e-07 | 43.48% (69) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2463 | - | 2e-15 | 34.59% (159) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2712 | - | 4e-07 | 44.12% (68) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 2e-07 | 43.48% (69) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1059 | - | 1e-17 | 39.66% (116) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRARVLE
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRARVLE
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
MAB_0647|M.abscessus_ATCC_1997 -----------------------------MDQPARPLRADAARNRARVLE
Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRARVLE
MMAR_1637|M.marinum_M --------------------MSGVEGLGELPVSARQERGDAARNRELLLQ
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNRELLLQ
TH_2712|M.thermoresistible__bu ----VSLMSADELLP----ARPATDVAAPTATTAPPEREDAARNRALLLD
MAV_2463|M.avium_104 ----------------------------MTAVEDRPLRSDAARNVERILR
Mvan_1059|M.vanbaalenii_PYR-1 ----------------------------MIDKPCRGLRKDAERNRQRVLT
MSMEG_1596|M.smegmatis_MC2_155 ----------------------------MTETPVRRRRADAQRNRDAILR
* ** ** :*
Mb0068c|M.bovis_AF2122/97 VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
Rv0067c|M.tuberculosis_H37Rv VAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH
MLBr_00316|M.leprae_Br4923 VAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
MAB_0647|M.abscessus_ATCC_1997 VAYQTFAEEG-LGVPIDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDRMG
Mflv_0142|M.gilvum_PYR-GCK VAYDTFAAEG-LTVPIDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVR
MMAR_1637|M.marinum_M AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
MUL_3399|M.ulcerans_Agy99 AARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMVLLDEDER
TH_2712|M.thermoresistible__bu AARRLIAERGAEAVTMDDIAAAAGVGKGTLFRRFGSRAGLMLELLHDDET
MAV_2463|M.avium_104 AAREVYAELG-PDAPVEAVARRAGVGERTLYRRFPAKADLVRAALDQSIA
Mvan_1059|M.vanbaalenii_PYR-1 AARELFAVEG-MEASLNDVARHAGVGVGTVYRRFATKEELVEAIFESGVD
MSMEG_1596|M.smegmatis_MC2_155 AAREAFETDG-IFAPLDSIATAAGVGNATLYRNFPTRDDLLRAVLEDGVA
.* * .. : :* **** *::*.* :: * .
Mb0068c|M.bovis_AF2122/97 RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
Rv0067c|M.tuberculosis_H37Rv RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALAGVG-IEIS
MLBr_00316|M.leprae_Br4923 HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDIL
MAB_0647|M.abscessus_ATCC_1997 SVIDKGRELLAAVDPGEALFEFLRSM-MDWGGTDQGLVDALSGAG-IDVQ
Mflv_0142|M.gilvum_PYR-GCK RIAERARTLLAVEGPGQALFVFFRDM-VRSAAVDHGLVDALMNQG-LDLE
MMAR_1637|M.marinum_M ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
MUL_3399|M.ulcerans_Agy99 ASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSEAN-RNPL
TH_2712|M.thermoresistible__bu AFQQAFMFGPPPLGPGAEPLERLLAYGRRRLQFVCDHHALLTDVS-REPQ
MAV_2463|M.avium_104 EDLTPVIDSARHAKDPLHGLTRLVEAAISLGAREQNLLAAAHRAG-----
Mvan_1059|M.vanbaalenii_PYR-1 EVVCLAEAALRHQDS-WEGFVWFVERQCLLTATDRGLREMVYSKA--YGG
MSMEG_1596|M.smegmatis_MC2_155 EMVAESEAYERHSDAEEALRDWLFRVTWALRIWHDLPNCIATAHD--DAE
:
Mb0068c|M.bovis_AF2122/97 SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQS--
Rv0067c|M.tuberculosis_H37Rv SAAPEAEADFLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVGCQAMQS--
MLBr_00316|M.leprae_Br4923 GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEA--
MAB_0647|M.abscessus_ATCC_1997 ALIPHIEESFYAVLGDLLRAAQQAGTVRSDVGVHEVKALLVGCQAMQS--
Mflv_0142|M.gilvum_PYR-GCK AVAPGVEAAFLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVVCKVPQV--
MMAR_1637|M.marinum_M TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLN--
MUL_3399|M.ulcerans_Agy99 TRYGAAASVHRRHVRVLLESADTTGDLDVQTDALLALLDVDYVEHQLN--
TH_2712|M.thermoresistible__bu TRFGPPMTLHHTHIRSLLAAADADGDLDVQADALLALTDPDYVRHQVT--
MAV_2463|M.avium_104 SLTSDISVSLNEALGELVREGQRAGRIRADLVADDLPRLVAMLYSVLSTM
Mvan_1059|M.vanbaalenii_PYR-1 NRVERVRERLAPLMKELVERARRDGYLRPDVESTDMPVIGLLAGTVGEWA
MSMEG_1596|M.smegmatis_MC2_155 SPVRPVTDRMTDRTARLLDN-YRAGKGPSPVTAEELFQLVTAVSWAVDRF
*: *
Mb0068c|M.bovis_AF2122/97 ------YNAELAAKVTDVALDGLRANRK----------------------
Rv0067c|M.tuberculosis_H37Rv ------YNAELAAKVTDVALDGLRANRK----------------------
MLBr_00316|M.leprae_Br4923 ------YNSALAERVTDVVVDGLRAAR-----------------------
MAB_0647|M.abscessus_ATCC_1997 ------YNKDVSRQVTDVVFDGLRPRP-----------------------
Mflv_0142|M.gilvum_PYR-GCK ------FDSEVTERVTRVIEDGLRPLR-----------------------
MMAR_1637|M.marinum_M ------DRGHTLRTLGDAWEDLARKLCGR---------------------
MUL_3399|M.ulcerans_Agy99 ------DRGHTLRTLGDAWEDLARKLCGR---------------------
TH_2712|M.thermoresistible__bu ------DRGVALDALADSWGDVARKLCRR---------------------
MAV_2463|M.avium_104 DAGSEGWRRYVALVVDAISVDERRPLPPAAALRYASQPNSWPL-------
Mvan_1059|M.vanbaalenii_PYR-1 G----DVDPELWRRYVELLLEGMRCRPDQKPLDVDALGEEQMHAAMHGWD
MSMEG_1596|M.smegmatis_MC2_155 G-----DDRDRARRRLEFATSGLFDS------------------------
.
Mb0068c|M.bovis_AF2122/97 ---
Rv0067c|M.tuberculosis_H37Rv ---
MLBr_00316|M.leprae_Br4923 ---
MAB_0647|M.abscessus_ATCC_1997 ---
Mflv_0142|M.gilvum_PYR-GCK ---
MMAR_1637|M.marinum_M ---
MUL_3399|M.ulcerans_Agy99 ---
TH_2712|M.thermoresistible__bu ---
MAV_2463|M.avium_104 ---
Mvan_1059|M.vanbaalenii_PYR-1 PSG
MSMEG_1596|M.smegmatis_MC2_155 ---