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MGRKGWAGAPPRDDEEARTRIVEAALTCIERHGPSQTSLSDVADTLGITRRTVYRYFATTEDLFTAAAEV ALGGFVRRIETITADIDDVAGQLVEVVAFIVERLPEEPLLTLLLENDRTNQFSRRMLSAPVIDRCRVILR HSRIDWEGLGYVSDADIDELIEFLLRMIQSMVIAPPEPPRDSAALRSYLHRWVGPALTAGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4096 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4113 | - | 4e-59 | 54.00% (200) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1606 | - | 6e-34 | 41.97% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 2e-07 | 26.86% (175) | TetR/ACRR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-09 | 24.24% (198) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4765 | - | 3e-29 | 38.07% (197) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 1e-29 | 35.53% (197) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_1115 | - | 8e-36 | 40.20% (199) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 1e-39 | 44.16% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 4e-41 | 45.27% (201) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 3e-21 | 32.12% (165) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_2232 | - | 6e-59 | 54.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4096|M.gilvum_PYR-GCK -MGRKGWAGAPPRDDEEARTRIVEAALTCIERHGPSQTSLSDVADTLGIT
Mvan_2232|M.vanbaalenii_PYR-1 -MGRKGWRGAPPADDREARQRILDAALASIERRGPRLTTLTEVAADLGIT
MSMEG_5854|M.smegmatis_MC2_155 -MRTHGWSGSAPATDEEAIARILAAAGKAIDERGA-DFSIADVARTLGVT
TH_1262|M.thermoresistible__bu -MRTHGWGGSAPASDEEAIARILEAAKRTIEERGA-EFSIADVARAVGVT
MAV_1115|M.avium_104 -MRRHGWSGDIPADDEEAVARILTATRRAIDERG--TVSVSQVASTLGVT
MMAR_0226|M.marinum_M MARRRGWNGAPPASDEEASRRIVDTAVRLIAETGS-DVSLAQVAASLGVI
MUL_4888|M.ulcerans_Agy99 MVSRPKRRGVSRIG------RGVRRHRRGIAETGS-DVSLAQVAASLGVI
MAB_4765|M.abscessus_ATCC_1997 MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETGS-AVSLADVAAELGVI
Rv1255c|M.tuberculosis_H37Rv -MAGTDWLS--ARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCS
Mb0237|M.bovis_AF2122/97 -MPTVTWARVDPAR----RAAVVEAAEAEFGAHGFSRGSLNVIARRAGVA
: : . : :* *
Mflv_4096|M.gilvum_PYR-GCK RRTVYRYFATTEDLFTAAAEVALGGFVRRIETITADID------DVAGQL
Mvan_2232|M.vanbaalenii_PYR-1 RPTIYRHFTSSEDLLAAAAEIALDHWTARIGEMSGHFT------DATDLL
MSMEG_5854|M.smegmatis_MC2_155 RQTVYRYFPSTDALLVAAAVHAASGFLDRLAAHLSGIT------DPVEAV
TH_1262|M.thermoresistible__bu RQTVYRYFPSTDALLVAAAMHAAGDFLDRLAVHLQGIT------DPVEAV
MAV_1115|M.avium_104 RQTIYRYFPTHEALLGATALSAVEGFLDRLAAHLGSIT------DPTEAV
MMAR_0226|M.marinum_M RQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMR------DPAEAM
MUL_4888|M.ulcerans_Agy99 RQTVYRYYPTADALMRAAAIASVDGFLDRLTEAVRGMR------DPAEAM
MAB_4765|M.abscessus_ATCC_1997 RQTVYRYFPTADALMHAASLASVDGFLDRLTHVVRGIT------DPAEAL
Rv1255c|M.tuberculosis_H37Rv RATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVV------EPAERL
Mb0237|M.bovis_AF2122/97 KGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPNRPFFEFLTDL
: :::::: * : . : :
Mflv_4096|M.gilvum_PYR-GCK VEVVAFIVERLPEEPLLTLLLENDRTNQFSRRMLSAPVIDRCRVILRHSR
Mvan_2232|M.vanbaalenii_PYR-1 VEAVAYLIERLPDEPLLGLLLETDRMRVMSRKMVMPAAVARSRTMLEHTG
MSMEG_5854|M.smegmatis_MC2_155 TEAIATALEWVPQDKHLGLLISPGRADAHTESVTSDVAVDFARAMLRKFD
TH_1262|M.thermoresistible__bu AEAIATTLEWLPEDTHIGLLVAPGRPTAHTESVTSDVAIDFANRMLRRFD
MAV_1115|M.avium_104 VEGIAYTFEQLAHDRYLSLVFQPGKASAFTAGVTSDIAISFGRSILQRFE
MMAR_0226|M.marinum_M AEAVMFTLRDVVRTPHLGILIAQPYAHTHPENLTSEEAQVFGVRMLERFD
MUL_4888|M.ulcerans_Agy99 AEAVMFTLRDVVRTPHLGILIAQPYAHTHPENLTSEEAQVFGVRMLERFD
MAB_4765|M.abscessus_ATCC_1997 TEGVLYTLEEVTRTPHLGIMMSEPYAHSHTSDMTSDEAQAFGLRMLDRFD
Rv1255c|M.tuberculosis_H37Rv LVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLN--
Mb0237|M.bovis_AF2122/97 LDGWVAYFAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVLRPLVR
. :
Mflv_4096|M.gilvum_PYR-GCK IDWEGLGYVSDADIDELIEFLLRMIQSMVIAPPE------------PPRD
Mvan_2232|M.vanbaalenii_PYR-1 IDWSAMGFTG-RRMDDLVEFLLRMIQSMVIAPSN------------PARS
MSMEG_5854|M.smegmatis_MC2_155 VDWAGLGFGDDDLD-ELAEHLLRIIQSFIIDPGR------------PPRT
TH_1262|M.thermoresistible__bu VDWAAVGYSDADLD-ELAEHLLRVIQSFVIDPGR------------PPRD
MAV_1115|M.avium_104 VDWGAAGFADAGLD-ELVEVMLRTLQSLIVDPGR------------PPRT
MMAR_0226|M.marinum_M VDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV------------PSRS
MUL_4888|M.ulcerans_Agy99 VDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV------------PSRS
MAB_4765|M.abscessus_ATCC_1997 VDWVQYGY-DDAAKRELVEFALRIMLSFFVSPNE------------ATRS
Rv1255c|M.tuberculosis_H37Rv ----SLGPDDPTTVERRARWVVRMLTSLLMFPGRD-----------EADE
Mb0237|M.bovis_AF2122/97 DAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQ
. : : : : * .
Mflv_4096|M.gilvum_PYR-GCK SAALRSYLHRWVGPALTAGR--------------
Mvan_2232|M.vanbaalenii_PYR-1 AAALRGYLRQWIGPVMSAGAGDLS----------
MSMEG_5854|M.smegmatis_MC2_155 GATLRSYLRRWVGAAVKPAQASVQSPRV------
TH_1262|M.thermoresistible__bu GQSLRAYLRRWVGAAVTGAR--------------
MAV_1115|M.avium_104 GAELRRFLQDWVAPAVRAHAISR-----------
MMAR_0226|M.marinum_M DDELKSFIKRWVGGAILAQKR-------------
MUL_4888|M.ulcerans_Agy99 DDELKSFIRRWVGGAIVAQKR-------------
MAB_4765|M.abscessus_ATCC_1997 RDELRGFLKRWLGGAVLAQGR-------------
Rv1255c|M.tuberculosis_H37Rv RAMIAEFVVPIVTPASAAARKAGHPGPE------
Mb0237|M.bovis_AF2122/97 PALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT
: : .